Reference on EC 6.1.1.15 - proline-tRNA ligase
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Ogata, K.; Kurahashi, A.; Tanaka, S.; Ohsue, H.; Terao, K.
Occurence of 5SrRNA in high molecular weight complexes of aminoacyl-tRNA synthetases in a rat liver supernatant
J. Biochem.
110
1030-1036
1991
Rattus norvegicus
Walker, E.J.; Treacy, G.B.; Jeffrey, P.D.
Molecular weights of mitochondrial and cytoplasmic aminoacyl-tRNA synthetases of beef liver and their complexes
Biochemistry
22
1934-1941
1983
Bos taurus
Norcum, M.T.
Isolation and electron microscopic characterization of the high molecular mass aminoacyl-tRNA synthetase complex from murine erythroleukemia cells
J. Biol. Chem.
264
15043-15051
1989
Mus musculus
Heacock, D.; Forsyth, C.J.; Shiba, K.; Musier-Forsyth, K.
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of prolyl adenylate analogs
Bioorg. Chem.
24
273-289
1996
Escherichia coli
-
Kerjan, P.; Triconnet, M.; Waller, J.P.
Mammalian prolyl-tRNA synthetase corresponds to the approximately 150 kDa subunit of the high-Mr aminoacyl-tRNA synthetase complex
Biochimie
74
195-205
1992
Homo sapiens, Mammalia, Ovis aries
Ting, S.M.; Bogner, P.; Dignam, J.D.
Isolation of prolyl-tRNA synthetase as a free form and as a form associated with glutamyl-tRNA synthetase
J. Biol. Chem.
267
17701-17709
1992
Rattus norvegicus
Stehlin, C.; Heacock, D.H.; Liu, H.; Musier-Forsyth, K.
Chemical modification and site-directed mutagenesis of the single cysteine in motif 3 of class II Escherichia coli prolyl-tRNA synthetase
Biochemistry
36
2932-2938
1997
Escherichia coli
Bianchi, C.; Perego R.; Del Monte, U.
Polypeptide composition of the 8S form of prolyl-tRNA synthetase from rat liver
Biochem. Biophys. Res. Commun.
187
1071-1076
1992
Rattus norvegicus
Rivera, J.A.; Wang, Q.S.; Wong, J.T.F.
A highly thermostable proline:tRNA ligase from Thermus aquaticus. Purification and enzyme-tRNA recognition at elevated temperatures
Can. J. Biochem. Cell Biol.
62
507-515
1984
Thermus aquaticus
Busiello, V.; Di Girolamo, M.; Cini, C.; De Marco, C.
beta-Selenaproline as competitive inhibitor of proline activation
Biochim. Biophys. Acta
606
347-352
1980
Escherichia coli, Rattus norvegicus
Arbeeny, C.M.; Briden, K.L.; Stirewalt, W.S.
The activity and sedimentation properties of the aminoacyl-tRNA synthetases of rat skeletal muscle
Biochim. Biophys. Acta
564
191-201
1979
Rattus norvegicus
Jeannin, G.; Burkard, G.; Weil, J.H.
Aminoacylation of Phaseolus vulgaris cytoplasmic, chloroplastic and mitochondrial tRNAsPro and tRNAsLys by homologous and heterologous enzymes
Biochim. Biophys. Acta
442
24-31
1976
Escherichia coli, Phaseolus vulgaris
Norris, R.D.; Fowden, L.
Cold-lability of prolyl-tRNA synthetase from higher plants
Phytochemistry
13
1677-1687
1974
Delonix regia, Phaseolus vulgaris
-
Norris, R.D.; Fowden, L.
Pro-tRNA synthetase from Phaseolus aureus and Delonix regia
Phytochemistry
12
2829-2841
1973
Delonix regia, Phaseolus vulgaris
-
Norris, R.D.; Fowden, L.
A Comparison of the thermal stability and substrate binding constants of prolyl-tRNA synthetase from Phaseolus aureus and Delonix regia
Phytochemistry
12
2109-2121
1973
Delonix regia, Phaseolus vulgaris
-
Norris, R.D.; Fowden, L.
Substrate discrimination by prolyl-tRNA synthetase from various higher plants
Phytochemistry
11
2921-2935
1972
Beta vulgaris, Convallaria majalis, Delonix regia, Hemerocallis fulva, Parkinsonia aculeata, Phaseolus vulgaris, Polygonatum multiflorum, Ranunculus bulbosus
-
Papas, T.S.; Mehler, A.H.
Kinetic studies of the prolyl transfer ribonucleic acid synthetase of Escherichia coli. Order of addition of substrates and release of products
J. Biol. Chem.
246
5924-5928
1971
Escherichia coli
Norton, S.J.
Purification and properties of the prolyl RNA synthetase of Escherichia coli
Arch. Biochem. Biophys.
106
147-152
1964
Escherichia coli, Escherichia coli 9723
Peterson, P.J.; Fowden, L.
Purification, properties and comparative specificities of the enzyme prolyl-transfer ribonucleic acid synthetase from Phaseolus aureus and Polygonatum multiflorum
Biochem. J.
97
112-124
1965
Asparagus officinalis, Convallaria majalis, Phaseolus vulgaris, Pisum sativum, Polygonatum multiflorum
Yaremchuk, A.; Kriklivyi, I.; Cusack, S.; Tukalo, M.
Improved crystals of Thermus thermophilus prolyl-tRNA synthetase complexed with cognate tRNA obtained by crystallization from precipitate
Acta Crystallogr. Sect. D
56
197-199
2000
Thermus thermophilus
Stathopoulos, C.; Jacquin-Becker, C.; Becker, H.D.; Li, T.; Ambrogelly, A.; Longman, R.; Soll, D.
Methanococcus jannaschii prolyl-cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites
Biochemistry
40
46-52
2001
Methanocaldococcus jannaschii (Q58635), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58635)
Wong, F.C.; Beuning, P.J.; Nagan, M.; Shiba, K.; Musier-Forsyth, K.
Functional role of the prokaryotic proline-tRNA synthetase insertion domain in amino acid editing
Biochemistry
41
7108-7115
2002
Escherichia coli
Yu, X.Y.; Hill, J.M.; Yu, G.; Yang, Y.; Kluge, A.F.; Keith, D.; Finn, J.; Gallant, P.; Silverman, J.; Lim, A.
A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase
Bioorg. Med. Chem. Lett.
11
541-544
2001
Candida albicans, Homo sapiens
Yaremchuk, A.; Cusack, S.; Tukalo, M.
Crystal structure of a eukaryote/archaeon-like protyl-tRNA synthetase and its complex with tRNAPro(CGG)
EMBO J.
19
4745-4758
2000
Thermus thermophilus
Jacquin-Becker, C.; Ahel, I.; Ambrogelly, A.; Ruan, B.; Soll, D.; Stathopoulos, C.
Cysteinyl-tRNA formation and prolyl-tRNA synthetase
FEBS Lett.
514
34-36
2002
Thermus thermophilus, Giardia intestinalis, Methanocaldococcus jannaschii, Methanococcus maripaludis
Norcum, M.T.; Dignam, J.D.
Immunoelectron microscopic localization of glutamyl-/prolyl-tRNA synthetase within the eukaryotic multisynthetase complex
J. Biol. Chem.
274
12205-12208
1999
Oryctolagus cuniculus
Nathanson, L.; Deutscher, M.P.
Active aminoacyl-tRNA synthetases are present in nuclei as a high molecular weight multienzyme complex
J. Biol. Chem.
275
31559-31562
2000
Cricetulus griseus
Burke, B.; Lipman, R.S.A.; Shiba, K.; Musier-Forsyth, K.; Hou, Y.M.
Divergent adaptation of tRNA recognition by Methanococcus jannaschii prolyl-tRNA synthetase
J. Biol. Chem.
276
20286-20291
2001
Methanocaldococcus jannaschii (Q58635), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58635)
Beuning, P.J.; Musier-Forsyth, K.
Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase
J. Biol. Chem.
276
30779-30785
2001
Escherichia coli, Homo sapiens, Methanocaldococcus jannaschii
Ahel, I.; Stathopoulos, C.; Ambrogelly, A.; Sauerwald, A.; Toogood, H.; Hartsch, T.; Soll, D.
Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases
J. Biol. Chem.
277
34743-34748
2002
Acetoanaerobium sticklandii, Aquifex aeolicus, Borreliella burgdorferi, Cytophaga hutchinsonii, Deinococcus radiodurans, Escherichia coli, Magnetospirillum magnetotacticum, Methanocaldococcus jannaschii, Methanothermobacter thermautotrophicus, Novosphingobium aromaticivorans, Rhodopseudomonas palustris, Saccharomyces cerevisiae, Thermus thermophilus
Ambrogelly, A.; Ahel, I.; Polycarpo, C.; Bunjun-Srihari, S.; Krett, B.; Jacquin-Becker, C.; Ruan, B.; Kohrer, C.; Stathopoulos, C.; RajBhandary, U.L.; Soll, D.
Methanocaldococcus jannaschii prolyl-tRNA synthetase charges tRNA(Pro) with cysteine
J. Biol. Chem.
277
34749-34754
2002
Methanocaldococcus jannaschii
Yaremchuk, A.; Tukalo, M.; Grotli, M.; Cusack, S.
A succession of substrate induced conformational changes ensures the amino acid specificity of Thermus thermophilus prolyl-tRNA synthetase: comparison with histidyl-tRNA synthetase
J. Mol. Biol.
309
989-1002
2001
Thermus thermophilus
Kamtekar, S.; Kennedy, W.D.; Wang, J.; Stathopoulos, C.; Soll, D.; Steitz, T.A.
The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc. Natl. Acad. Sci. USA
100
1673-1678
2003
Methanocaldococcus jannaschii, Methanothermobacter thermautotrophicus
Stathopoulos, C.; Kim, W.; Li, T.; Anderson, I.; Deutsch, B.; Palioura, S.; Whitman, W.; Soll, D.
Cysteinyl-tRNA synthetase is not essential for viability of the archaeon Methanococcus maripaludis
Proc. Natl. Acad. Sci. USA
98
14292-14297
2001
Methanococcus maripaludis (Q6LZD3), Methanococcus maripaludis
Cusack, S.; Yaremchuk, A.; Krikliviy, I.; Tukalo, M.
tRNAPro anticodon recognition by Thermus thermophilus prolyl-tRNA synthetase
Structure
6
101-108
1998
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Murayama, K.; Kato-Murayama, M.; Katsura, K.; Uchikubo-Kamo, T.; Yamaguchi-Hirafuji, M.; Kawazoe, M.; Akasaka, R.; Hanawa-Suetsugu, K.; Hori-Takemoto, C.; Terada, T.; Shirouzu, M.; Yokoyama, S.
Structure of a putative trans-editing enzyme for prolyl-tRNA synthetase from Aeropyrum pernix K1 at 1.7 A resolution
Acta Crystallogr. Sect. F
61
26-29
2005
Aeropyrum pernix
Sampath, P.; Mazumder, B.; Seshadri, V.; Gerber, C.A.; Chavatte, L.; Kinter, M.; Ting, S.M.; Dignam, J.D.; Kim, S.; Driscoll, D.M.; Fox, P.L.
Noncanonical function of glutamyl-prolyl-tRNA synthetase: Gene-specific silencing of translation
Cell
119
195-208
2004
Homo sapiens
Ambrogelly, A.; Kamtekar, S.; Stathopoulos, C.; Kennedy, D.; Soll, D.
Asymmetric behavior of archaeal prolyl-tRNA synthetase
FEBS Lett.
579
6017-6022
2005
Methanothermobacter thermautotrophicus, Methanocaldococcus jannaschii
Praetorius-Ibba, M.; Rogers, T.E.; Samson, R.; Kelman, Z.; Ibba, M.
Association between Archaeal prolyl- and leucyl-tRNA synthetases enhances tRNA(Pro) aminoacylation
J. Biol. Chem.
280
26099-26104
2005
Methanothermobacter thermautotrophicus
An, S.; Musier-Forsyth, K.
Cys-tRNA(Pro) editing by Haemophilus influenzae YbaK via a novel synthetase.YbaK.tRNA ternary complex
J. Biol. Chem.
280
34465-34472
2005
Haemophilus influenzae
Hati, S.; Ziervogel, B.; Sternjohn, J.; Wong, F.C.; Nagan, M.C.; Rosen, A.E.; Siliciano, P.G.; Chihade, J.W.; Musier-Forsyth, K.
Pre-transfer editing by class II prolyl-tRNA synthetase: role of aminoacylation active site in 'selective release' of noncognate amino acids
J. Biol. Chem.
281
27862-27872
2006
Saccharomyces cerevisiae, Escherichia coli, Methanothermobacter thermautotrophicus, Methanocaldococcus jannaschii, Methanococcus maripaludis
Praetorius-Ibba, M.; Hausmann, C.D.; Paras, M.; Rogers, T.E.; Ibba, M.
Functional association between three archaeal aminoacyl-tRNA synthetases
J. Biol. Chem.
282
3680-3687
2007
Methanothermobacter thermautotrophicus
Zhang, C.M.; Perona, J.J.; Ryu, K.; Francklyn, C.; Hou, Y.M.
Distinct kinetic mechanisms of the two classes of aminoacyl-tRNA synthetases
J. Mol. Biol.
361
300-311
2006
Deinococcus radiodurans
Crepin, T.; Yaremchuk, A.; Tukalo, M.; Cusack, S.
Structures of two bacterial prolyl-tRNA synthetases with and without a cis-editing domain
Structure
14
1511-1525
2006
Rhodopseudomonas palustris (Q6N5P6), Rhodopseudomonas palustris, Enterococcus faecalis (Q831W7), Enterococcus faecalis
Burke, B.; An, S.; Musier-Forsyth, K.
Functional guanine-arginine interaction between tRNAPro and prolyl-tRNA synthetase that couples binding and catalysis
Biochim. Biophys. Acta
1784
1222-1225
2008
Escherichia coli
Splan, K.E.; Ignatov, M.E.; Musier-Forsyth, K.
Transfer RNA modulates the editing mechanism used by class II prolyl-tRNA synthetase
J. Biol. Chem.
283
7128-7134
2008
Escherichia coli, Homo sapiens, Methanocaldococcus jannaschii
Wei, M.; Yang, Y.; Niu, M.; Desfosse, L.; Kennedy, R.; Musier-Forsyth, K.; Kleiman, L.
Inability of HIV-1 produced in murine cells to selectively incorporate primer tRNALys3
J. Virol.
82
12049-12059
2008
Moloney murine leukemia virus
Koehrer, C.; Rajbhandary, U.L.
The many applications of acid urea polyacrylamide gel electrophoresis to studies of tRNAs and aminoacyl-tRNA synthetases
Methods
44
129-138
2008
Methanothermobacter thermautotrophicus, Methanocaldococcus jannaschii, Methanopyrus kandleri
Jia, J.; Arif, A.; Ray, P.S.; Fox, P.L.
WHEP domains direct noncanonical function of glutamyl-prolyl tRNA synthetase in translational control of gene expression
Mol. Cell
29
679-690
2008
Homo sapiens
An, S.; Barany, G.; Musier-Forsyth, K.
Evolution of acceptor stem tRNA recognition by class II prolyl-tRNA synthetase
Nucleic Acids Res.
36
2514-2521
2008
Homo sapiens
Chatterjee, A.; Xiao, H.; Schultz, P.G.
Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli
Proc. Natl. Acad. Sci. USA
109
14841-14846
2012
Pyrococcus horikoshii
Larson, E.T.; Kim, J.E.; Napuli, A.J.; Verlinde, C.L.; Fan, E.; Zucker, F.H.; Van Voorhis, W.C.; Buckner, F.S.; Hol, W.G.; Merritt, E.A.
Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia
Acta Crystallogr. Sect. D
68
1194-1200
2012
Giardia intestinalis (A8BR89), Giardia intestinalis, Giardia intestinalis WB / CC 30957 (A8BR89)
Son, J.; Lee, E.H.; Park, M.; Kim, J.H.; Kim, J.; Kim, S.; Jeon, Y.H.; Hwang, K.Y.
Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone
Acta Crystallogr. Sect. D
69
2136-2145
2013
Homo sapiens (P07814), Homo sapiens
Sanford, B.; Cao, B.; Johnson, J.M.; Zimmerman, K.; Strom, A.M.; Mueller, R.M.; Bhattacharyya, S.; Musier-Forsyth, K.; Hati, S.
Role of coupled dynamics in the catalytic activity of prokaryotic-like prolyl-tRNA synthetases
Biochemistry
51
2146-2156
2012
Escherichia coli (P16659), Escherichia coli
Johnson, J.M.; Sanford, B.L.; Strom, A.M.; Tadayon, S.N.; Lehman, B.P.; Zirbes, A.M.; Bhattacharyya, S.; Musier-Forsyth, K.; Hati, S.
Multiple pathways promote dynamical coupling between catalytic domains in Escherichia coli prolyl-tRNA synthetase
Biochemistry
52
4399-4412
2013
Escherichia coli
Bartholow, T.G.; Sanford, B.L.; Cao, B.; Schmit, H.L.; Johnson, J.M.; Meitzner, J.; Bhattacharyya, S.; Musier-Forsyth, K.; Hati, S.
Strictly conserved lysine of prolyl-tRNA synthetase editing domain facilitates binding and positioning of misacylated tRNAPro
Biochemistry
53
1059-1068
2014
Escherichia coli
Feng, L.; Stathopoulos, C.; Ahel, I.; Mitra, A.; Tumbula-Hansen, D., Hartsch, T.; Sll, D.
Aminoacyl-tRNA formation in the extreme thermophile Thermus thermophilus
Extremophiles
6
167-174
2002
Thermus thermophilus (Q5SM28), Thermus thermophilus, Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 (Q5SM28)
Kumar, S.; Das, M.; Hadad, C.M.; Musier-Forsyth, K.
Substrate specificity of bacterial prolyl-tRNA synthetase editing domain is controlled by a tunable hydrophobic pocket
J. Biol. Chem.
287
3175-3184
2012
Escherichia coli
Lipman, R.S.; Wang, J.; Sowers, K.R.; Hou, Y.M.
Prevention of mis-aminoacylation of a dual-specificity aminoacyl-tRNA synthetase
J. Mol. Biol.
315
943-999
2002
Methanocaldococcus jannaschii (Q58635), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58635)
Lipman, R.S.; Beuning, P.J.; Musier-Forsyth, K.; Hou, Y.M.
Amino acid activation of a dual-specificity tRNA synthetase is independent of tRNA
J. Mol. Biol.
316
421-427
2002
Methanocaldococcus jannaschii (Q58635), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58635)
Saravanan Prabhu, N.; Ayyadurai, N.; Deepankumar, K.; Chung, T.; Lim, D.; Yun, H.
Reassignment of sense codons: Designing and docking of proline analogs for Escherichia coli prolyl-tRNA synthetase to expand the genetic code
J. Mol. Catal. B
78
57-64
2012
Escherichia coli
-
Keller, T.L.; Zocco, D.; Sundrud, M.S.; Hendrick, M.; Edenius, M.; Yum, J.; Kim, Y.J.; Lee, H.K.; Cortese, J.F.; Wirth, D.F.; Dignam, J.D.; Rao, A.; Yeo, C.Y.; Mazitschek, R.; Whitman, M.
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase
Nat. Chem. Biol.
8
311-317
2012
Homo sapiens
Yokozawa, J.; Okamoto, K.; Kawarabayasi, Y.; Kuno, A.; Hasegawa, T.
Molecular recognition of proline tRNA by prolyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1
Nucleic Acids Res. Suppl.
2003
247-248
2003
Aeropyrum pernix (Q9Y9G0), Aeropyrum pernix, Aeropyrum pernix DSM 11879 (Q9Y9G0)
Bunjun, S.; Stathopoulos, C.; Graham, D.; Min, B.; Kitabatake, M.; Wang, A.L.; Wang, C.C.; Vivars, C.P.; Weiss, L.M.; Sll, D.
A dual-specificity aminoacyl-tRNA synthetase in the deep-rooted eukaryote Giardia lamblia
Proc. Natl. Acad. Sci. USA
97
12997-13002
2000
Giardia intestinalis (Q9GQI4), Giardia intestinalis
Hewitt, S.N.; Dranow, D.M.; Horst, B.G.; Abendroth, J.A.; Forte, B.; Hallyburton, I.; Jansen, C.; Baragana, B.; Choi, R.; Rivas, K.L.; Hulverson, M.A.; Dumais, M.; Edwards, T.E.; Lorimer, D.D.; Fairlamb, A.H.; Gray, D.W.; Read, K.D.; Lehane, A.M.; Kirk, K.; Myler, P.J.; Wernimont, A.; Walpole, C.; Stacy, R.; Bar, B.a.r.r.
Biochemical and Structural characterization of selective allosteric inhibitors of the Plasmodium falciparum drug target, prolyl-tRNA-synthetase
ACS Infect. Dis.
3
34-44
2017
Plasmodium falciparum (Q8I5R7), Plasmodium falciparum
Adachi, R.; Okada, K.; Skene, R.; Ogawa, K.; Miwa, M.; Tsuchinaga, K.; Ohkubo, S.; Henta, T.; Kawamoto, T.
Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with L-proline
Biochem. Biophys. Res. Commun.
488
393-399
2017
Homo sapiens (P07814), Homo sapiens
Young, S.K.; Baird, T.D.; Wek, R.C.
Translation regulation of the glutamyl-prolyl-tRNA synthetase gene EPRS through bypass of upstream open reading frames with noncanonical initiation codons
J. Biol. Chem.
291
10824-10835
2016
Mus musculus
Boyarshin, K.S.; Priss, A.E.; Rayevskiy, A.V.; Ilchenko, M.M.; Dubey, I.Y.; Kriklivyi, I.A.; Yaremchuk, A.D.; Tukalo, M.A.
A new mechanism of post-transfer editing by aminoacyl-tRNA synthetases catalysis of hydrolytic reaction by bacterial-type prolyl-tRNA synthetase
J. Biomol. Struct. Dyn.
35
669-682
2017
Enterococcus faecalis (Q831W7), Enterococcus faecalis
Jain, V.; Kikuchi, H.; Oshima, Y.; Sharma, A.; Yogavel, M.
Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase
J. Struct. Funct. Genomics
15
181-190
2014
Plasmodium falciparum (Q8I5R7), Plasmodium falciparum
Lee, E.Y.; Lee, H.C.; Kim, H.K.; Jang, S.Y.; Park, S.J.; Kim, Y.H.; Kim, J.H.; Hwang, J.; Kim, J.H.; Kim, T.H.; Arif, A.; Kim, S.Y.; Choi, Y.K.; Lee, C.; Lee, C.H.; Jung, J.U.; Fox, P.L.; Kim, S.; Lee, J.S.; Kim, M.H.
Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity
Nat. Immunol.
17
1252-1262
2016
Homo sapiens (P07814), Mus musculus (Q8CGC7), Mus musculus C57BL/6 (Q8CGC7)
Lee, J.; Joshi, N.; Pasini, R.; Dobson, R.C.; Allison, J.; Leustek, T.
Inhibition of Arabidopsis growth by the allelopathic compound azetidine-2-carboxylate is due to the low amino acid specificity of cytosolic prolyl-tRNA synthetase
Plant J.
88
236-246
2016
Arabidopsis thaliana
Ravishankar, S.; Ambady, A.; Swetha, R.G.; Anbarasu, A.; Ramaiah, S.; Sambandamurthy, V.K.
Essentiality assessment of cysteinyl and lysyl-tRNA synthetases of Mycobacterium smegmatis
PLoS ONE
11
e0147188
2016
Mycolicibacterium smegmatis (A0QVM0), Mycolicibacterium smegmatis mc2155 / ATCC 700084 (A0QVM0)
Jain, V.; Yogavel, M.; Oshima, Y.; Kikuchi, H.; Touquet, B.; Hakimi, M.A.; Sharma, A.
Structure of prolyl-tRNA synthetase-halofuginone complex provides basis for development of drugs against malaria and toxoplasmosis
Structure
23
819-829
2015
Plasmodium falciparum (Q8I5R7), Toxoplasma gondii
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