Reference on EC 6.1.1.12 - aspartate-tRNA ligase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Walker, E.J.; Treacy, G.B.; Jeffrey, P.D.
Molecular weights of mitochondrial and cytoplasmic aminoacyl-tRNA synthetases of beef liver and their complexes
Biochemistry
22
1934-1941
1983
Bos taurus
Martin, F.; Sharples, G.J.; LLoyd, R.G.; Eiler, S.; Moras, D.; Gangloff, J.; Eriani, G.
Characterization of a thermosensitive Escherichia coli aspartyl-tRNA synthetase mutant
J. Bacteriol.
179
3691-3696
1997
Escherichia coli
Eiler, S.; Boeglin, M.; Martin, F.; Eriani, G.; Gangloff, J.; Thierry, J.C.; Moras, D.
Crystallization of aspartyl-tRNA synthetase-tRNA(Asp) complex from Escherichia coli and first crystallographic results
J. Mol. Biol.
224
1171-1173
1992
Escherichia coli
Escalante, C.; Qasba, P.K.; Yang, D.C.
Expression of human aspartyl-tRNA synthetase in COS cells
Mol. Cell. Biochem.
140
55-63
1994
Homo sapiens
Escalante, C.; Yang, D.C.
Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix
J. Biol. Chem.
268
6014-6023
1993
Bacteria, Saccharomyces cerevisiae, Homo sapiens, Mammalia
Cavarelli, J.; Rees, B.; Thierry, J.C.; Moras, D.
Yeast aspartyl-tRNA synthetase: a structural view of the aminoacylation reaction
Biochimie
75
1117-1123
1993
Saccharomyces cerevisiae
Mirande, M.; Lazard, M.; Martinez, R.; Latreille, M.T.
Engineering mammalian aspartyl-tRNA synthetase to probe structural features mediating its association with the multisynthetase complex
Eur. J. Biochem.
203
459-466
1992
Ovis aries, Rattus norvegicus
Eriani, G.; Prevost, G.; Kern, D.; Vincendon, P.; Dirheimer, G.; Gangloff, J.
Cytoplasmic aspartyl-tRNA synthetase from Saccharomyces cerevisiae. Study of its functional organisation by deletion analysis
Eur. J. Biochem.
200
337-343
1991
Saccharomyces cerevisiae
Agou, F.; Waller, J.P.; Mirande, M.
Expression of rat aspartyl-tRNA synthetase in Saccharomyces cerevisiae. Role of the NH2-terminal polypeptide extension on enzyme activity and stability
J. Biol. Chem.
271
29295-29303
1996
Mammalia, Rattus norvegicus
Fujiwara, S.; Lee, S.; Haruki, M.; Kanaya, S.; Takagi, M.; Imanaka, T.
Unusual enzyme characteristics of aspartyl-tRNA synthetase from hyperthermophilic archaeon Pyrococcus sp. KOD1
FEBS Lett.
394
66-70
1996
Homo sapiens, Pyrococcus sp., Thermococcus kodakarensis (Q52428), Pyrococcus sp. KOD1
Poterszman, A.; Plateau, P.; Moras, D.; Blanquet, S.; Mazauric, M.H.; Kreutzer, R.; Kern, D.
Sequence, overproduction and crystallization of aspartyl-tRNA synthetase from Thermus thermophilus
FEBS Lett.
325
183-186
1993
Thermus thermophilus (P36419), Thermus thermophilus, Thermus thermophilus VK-1 (P36419), Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (P36419)
Becker, H.D.; Reinbolt, J.; Kreutzer, R.; Giege, R.; Kern, D.
Existence of two distinct aspartyl-tRNA synthetases in Thermus thermophilus. Structural and biochemical properties of the two enzymes
Biochemistry
36
8785-8797
1997
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Gasparini, S.; Vincendon, P.; Eriani, G.; Gangloff, J.; Boulanger, Y.; Reinbolt, J.; Kern, D.
Identification of structurally and functionally important histidine residues in cytoplasmic aspartyl-tRNA synthetase from Saccharomyces cerevisiae
Biochemistry
30
4284-4289
1991
Saccharomyces cerevisiae
Agou, F.; Mirande, M.
Aspartyl-tRNA synthetase from rat. In vitro functional analysis of its assembly into multisynthetase complex
Eur. J. Biochem.
243
259-267
1997
Rattus norvegicus
Delarue, M.; Poterszman, A.; Nikonov, S.; Garber, M.; Moras, D.; Thierry, J.C.
Crystal structure of a prokaryotic aspartyl tRNA-synthetase
EMBO J.
13
3219-3229
1994
Thermus thermophilus
Eriani, G.; Caravelli.J.; Martin, F.; Dirheimer, G.; Moras, D.
Role of dimerization in yeast aspartyl-tRNA synthetase and importance of the class II invariant proline
Proc. Natl. Acad. Sci. USA
90
10816-10820
1993
Saccharomyces cerevisiae
Norton, S.J.; Ravel, J.M.; Lee, C.; Shive, W.
Purification and properties of the aspartyl ribonucleic acid synthetase of Lactobacillus arabinosus
J. Biol. Chem.
238
269-274
1963
Lactiplantibacillus plantarum
Lea, P.J.; Fowden, L.
Amino acid substrate specificity of asparaginyl-, aspartyl- and glutaminyl-tRNA synthetase isolated from higher plants
Phytochemistry
12
1903-1916
1973
Vigna radiata var. radiata
-
Gangloff, J; Dirheimer, G.
Studies on aspartyl-tRNA synthetase from baker's yeast. I. Purification and properties of the enzyme
Biochim. Biophys. Acta
294
263-272
1973
Saccharomyces cerevisiae, Saccharomyces cerevisiae C836
Akesson, B.; Lundvik, L.
Simultaneous purification and some properties of aspartate:tRNA ligase and seven other amino-acid:tRNA ligases from Escherichia coli
Eur. J. Biochem.
83
29-36
1978
Escherichia coli, Escherichia coli B / ATCC 11303
Dietrich, A.; Giege, R.; Comarmond, M.B.; Thierry, J.C.; Moras, D.
Crystallographic studies on the aspartyl-tRNA synthetase-tRNAAsp system from yeast
J. Mol. Biol.
138
129-135
1980
Saccharomyces cerevisiae
Drocourt, J.L.; Gangloff, J.; Dirheimer, G.; Thang, M.N.
Interaction of yeast arginyl-tRNA synthetase and aspartyl-tRNA synthetase with blue-dextran Sepharose: assignement of the blue-dextran binding site on the synthetase
Biochem. Biophys. Res. Commun.
97
787-793
1980
Saccharomyces cerevisiae
Vellekamp, G.J.; Kull, F.J.
Allotropism in aspartyl-tRNA synthetase from porcine thyroid
Eur. J. Biochem.
118
261-269
1981
Sus scrofa
Vellekamp, G.J.; Coyle, C.L.; Kull, F.J.
Low molecular weight aspartyl-tRNA synthetase from porcine thyroid. Purification, characterization, and heterogeneity
J. Biol. Chem.
258
8195-8200
1983
Sus scrofa
Lorber, B.; Kern, D.; Dietrich, A.; Gangloff, J.; Ebel, J.P.; Giege, R.
Large scale purification and structural properties of yeast aspartyl-tRNA synthetase
Biochem. Biophys. Res. Commun.
117
259-267
1983
Saccharomyces cerevisiae
Lorber, B.; Mejdoub, H.; Reinbolt, J.; Boulanger, Y.; Giege, R.
Properties of N-terminal truncated yeast aspartyl synthetase and structural characteristics of the cleaved domain
Eur. J. Biochem.
174
155-161
1988
Saccharomyces cerevisiae
Ruff, M.; Cavarelli, J.; Mikol, V.; Lorber, B.; Mitschler, A.; Giege, R.; Thierry, J.C.; Moras, D.
A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase
J. Mol. Biol.
201
235-236
1988
Saccharomyces cerevisiae
Goldgur, Y.; Safro, M.
Aminoacyl-tRNA synthetases from Haloarcula marismortui: an evidence for a multienzyme complex in a procaryotic system
Biochem. Mol. Biol. Int.
32
1075-1083
1994
Haloarcula marismortui
Norcum, M.T.
Isolation and electron microscopic characterization of the high molecular mass aminoacyl-tRNA synthetase complex from murine erythroleukemia cells
J. Biol. Chem.
264
15043-15051
1989
Mus musculus
Sivaram, P.; Vellekamp, G.; Deutscher, M.P.
A role for lipids in the functional and structural properties of the rat liver aminoacyl-tRNA synthetase complex
J. Biol. Chem.
263
18891-18896
1988
Rattus norvegicus
Becker, H.D.; Roy, H.; Moulinier, L.; Mazauric, M.H.; Keith, G.; Kern, D.
Thermus thermophilus contains an eubacterial and an archaebacterial aspartyl-tRNA synthetase
Biochemistry
39
3216-3230
2000
Thermus thermophilus (P36419), Thermus thermophilus (Q5SIC2), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (P36419), Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q5SIC2)
Tumbula-Hansen, D.; Feng, L.; Toogood, H.; Stetter, K.O.; Sll, D.
Evolutionary divergence of the archaeal aspartyl-tRNA synthetases into discriminating and nondiscriminating forms
J. Biol. Chem.
277
37184-37190
2002
Ferroplasma acidarmanus, Methanothermobacter thermautotrophicus, Thermococcus kodakarensis (Q52428), Thermococcus kodakarensis
Charron, C.; Roy, H.; Lorber, B.; Kern, D.; Giege, R.
Crystallization and preliminary X-ray diffraction data of the second and archaebacterial-type aspartyl-tRNA synthetase from Thermus thermophilus
Acta Crystallogr. Sect. D
57
1177-1179
2001
Thermus thermophilus
Zhu, D.W.; Lorber, B.; Sauter, C.; Ng, J.D.; Benas, P.; Le Grimellec, C.; Giege, R.
Growth kinetics, diffraction properties and effect of agarose on the stability of a novel crystal form of Thermus thermophilus aspartyl-tRNA synthetase-1
Acta Crystallogr. Sect. D
57
552-558
2001
Thermus thermophilus
Charron, C.; Kern, D.; Giege, R.
Crystal contacts engineering of aspartyl-tRNA synthetase from Thermus thermophilus: effects on crystallizability
Acta Crystallogr. Sect. D
58
1729-1733
2002
Thermus thermophilus
Wolfson, A.D.; Khvorova, A.M.; Sauter, C.; Florentz, C.; Giege, R.
Mimics of yeast tRNAAsp and their recognition by aspartyl-tRNA synthetase
Biochemistry
38
11926-11932
1999
Saccharomyces cerevisiae
Berthet-Colominas, C.; Seignovert, L.; Hartlein, M.; Grotli, M.; Cusack, S.; Leberman, R.
The crystal structure of asparaginyl-tRNA synthetase from Thermus thermophilus and its complexes with ATP and asparaginyl-adenylate: the mechanism of discrimination between asparagine and aspartic acid
EMBO J.
17
2947-2960
1998
Thermus thermophilus
Charron, C.; Roy, H.; Blaise, M.; Giege, R.; Kern, D.
Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain
EMBO J.
22
1632-1643
2003
Thermus thermophilus, Thermococcus kodakarensis
Cheong, H.K.; Park, J.Y.; Kim, E.H.; Lee, C.; Kim, S.; Kim, Y.; Choi, B.S.; Cheong, C.
Structure of the N-terminal extension of human aspartyl-tRNA synthetase: implications for its biological function
Int. J. Biochem. Cell Biol.
35
1548-1557
2003
Homo sapiens
Ryckelynck, M.; Giege, R.; Frugier, M.
Yeast tRNA(Asp) charging accuracy is threatened by the N-terminal extension of aspartyl-tRNA synthetase
J. Biol. Chem.
278
9683-9690
2003
Saccharomyces cerevisiae
Archontis, G.; Simonson, T.; Moras, D.; Karplus, M.
Specific amino acid recognition by aspartyl-tRNA synthetase studied by free energy simulations
J. Mol. Biol.
275
823-846
1998
Saccharomyces cerevisiae, Escherichia coli, Thermus thermophilus
Eriani, G.; Gangloff, J.
Yeast aspartyl-tRNA synthetase residues interacting with tRNA(Asp) identity bases connectively contribute to tRNA(Asp) binding in the ground and transition-state complex and discriminate against non-cognate tRNAs
J. Mol. Biol.
291
761-773
1999
Saccharomyces cerevisiae
Briand, C.; Poterszman, A.; Eiler, S.; Webster, G.; Thierry, J.; Moras, D.
An intermediate step in the recognition of tRNA(Asp) by aspartyl-tRNA synthetase
J. Mol. Biol.
299
1051-1060
2000
Thermus thermophilus
Rees, B.; Webster, G.; Delarue, M.; Boeglin, M.; Moras, D.
Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates
J. Mol. Biol.
299
1157-1164
2000
Escherichia coli
Sauter, C.; Lorber, B.; Cavarelli, J.; Moras, D.; Giege, R.
The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain
J. Mol. Biol.
299
1313-1324
2000
Saccharomyces cerevisiae (P04802), Saccharomyces cerevisiae
Archontis, G.; Simonson, T.; Karplus, M.
Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition by aspartyl-tRNA synthetase
J. Mol. Biol.
306
307-327
2001
Escherichia coli
Frugier, M.; Giege, R.
Yeast aspartyl-tRNA synthetase binds specifically its own mRNA
J. Mol. Biol.
331
375-383
2003
Saccharomyces cerevisiae
Choi, H.; Gabriel, K.; Schneider, J.; Otten, S.; McClain, W.H.
Recognition of acceptor-stem structure of tRNA(Asp) by Escherichia coli aspartyl-tRNA synthetase
RNA
9
386-393
2003
Escherichia coli
Moreno, A.; Theobald-Dietrich, A.; Lorber, B.; Sauter, C.; Giege, R.
Effects of macromolecular impurities and of crystallization method on the quality of eubacterial aspartyl-tRNA synthetase crystals
Acta Crystallogr. Sect. D
61
789-792
2005
Thermus thermophilus
Bonnefond, L.; Fender, A.; Rudinger-Thirion, J.; Giege, R.; Florentz, C.; Sissler, M.
Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS
Biochemistry
44
4805-4816
2005
Homo sapiens
Bernier, S.; Akochy, P.M.; Lapointe, J.; Chenevert, R.
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of aspartyl adenylate analogs
Bioorg. Med. Chem.
13
69-75
2005
Escherichia coli
Brevet, A.; Chen, J.; Commans, S.; Lazennec, C.; Blanquet, S.; Plateau, P.
Anticodon Recognition in Evolution: Switching tRNA specificity of an aminoacyl-tRNA synthetase by site-directed
J. Biol. Chem.
278
30927-30935
2003
Escherichia coli
Ryckelynck, M.; Masquida, B.; Giege, R.; Frugier, M.
An intricate RNA structure with two tRNA-derived motifs directs complex formation between yeast aspartyl-tRNA synthetase and its mRNA
J. Mol. Biol.
354
614-629
2005
Saccharomyces cerevisiae (P04802), Saccharomyces cerevisiae
Martin, F.; Barends, S.; Eriani, G.
Single amino acid changes in AspRS reveal alternative routes for expanding its tRNA repertoire in vivo
Nucleic Acids Res.
32
4081-4089
2004
Escherichia coli
Feng, L.; Tumbula-Hansen, D.; Toogood, H.; Soll, D.
Expanding tRNA recognition of a tRNA synthetase by a single amino acid change
Proc. Natl. Acad. Sci. USA
100
5676-5681
2003
Thermococcus kodakarensis, Thermococcus kodakarensis (Q52428)
Metlitskaya, A.; Kazakov, T.; Kommer, A.; Pavlova, O.; Praetorius-Ibba, M.; Ibba, M.; Krasheninnikov, I.; Kolb, V.; Khmel, I.; Severinov, K.
Aspartyl-tRNA synthetase is the target of peptide nucleotide antibiotic Microcin C
J. Biol. Chem.
281
18033-18042
2006
Francisella tularensis
Thompson, D.; Simonson, T.
Molecular dynamics simulations show that bound Mg2+ contributes to amino acid and aminoacyl adenylate binding specificity in aspartyl-tRNA synthetase through long range electrostatic interactions
J. Biol. Chem.
281
23792-23803
2006
Escherichia coli (P21889)
Thompson, D.; Lazennec, C.; Plateau, P.; Simonson, T.
Ammonium scanning in an enzyme active site. The chiral specificity of aspartyl-tRNA synthetase
J. Biol. Chem.
282
30856-30868
2007
Escherichia coli (P21889)
Scheper, G.C.; van der Klok, T.; van Andel, R.J.; van Berkel, C.G.; Sissler, M.; Smet, J.; Muravina, T.I.; Serkov, S.V.; Uziel, G.; Bugiani, M.; Schiffmann, R.; Kraegeloh-Mann, I.; Smeitink, J.A.; Florentz, C.; Van Coster, R.; Pronk, J.C.; van der Knaap, M.S.
Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation
Nat. Genet.
39
534-539
2007
Homo sapiens
Guzzo, C.M.; Yang, D.C.
Systematic analysis of fusion and affinity tags using human aspartyl-tRNA synthetase expressed in E. coli
Protein Expr. Purif.
54
166-175
2007
Homo sapiens
Guzzo, C.M.; Yang, D.C.
Lysyl-tRNA synthetase interacts with EF1alpha, aspartyl-tRNA synthetase and p38 in vitro
Biochem. Biophys. Res. Commun.
365
718-723
2008
Homo sapiens
Petit, V.W.; Zirah, S.; Rebuffat, S.; Tabet, J.C.
Collision induced dissociation-based characterization of nucleotide peptides: fragmentation patterns of microcin C7-C51, an antimicrobial peptide produced by Escherichia coli
J. Am. Soc. Mass Spectrom.
19
1187-1198
2008
Escherichia coli, Escherichia coli TG1
Kazakov, T.; Vondenhoff, G.H.; Datsenko, K.A.; Novikova, M.; Metlitskaya, A.; Wanner, B.L.; Severinov, K.
Escherichia coli peptidase A, B, or N can process translation inhibitor microcin C
J. Bacteriol.
190
2607-2610
2008
Escherichia coli
Uluc, K.; Baskan, O.; Yildirim, K.A.; Ozsahin, S.; Koseoglu, M.; Isak, B.; Scheper, G.C.; Gunal, D.I.; van der Knaap, M.S.
Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings
J. Neurol. Sci.
273
118-122
2008
Homo sapiens
Bailly, M.; Blaise, M.; Roy, H.; Deniziak, M.; Lorber, B.; Birck, C.; Becker, H.D.; Kern, D.
tRNA-dependent asparagine formation in prokaryotes: Characterization, isolation and structural and functional analysis of a ribonucleoprotein particle generating Asn-tRNAAsn
Methods
44
146-163
2008
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Thompson, D.; Lazennec, C.; Plateau, P.; Simonson, T.
Probing electrostatic interactions and ligand binding in aspartyl-tRNA synthetase through site-directed mutagenesis and computer simulations
Proteins
71
1450-1460
2008
Escherichia coli
Ryckelynck, M.; A Paulus, C.; Frugier, M.
Post-translational modifications guard yeast from misaspartylation
Biochemistry
47
12476-12482
2008
Saccharomyces cerevisiae
Messmer, M.; Blais, S.P.; Balg, C.; Chenevert, R.; Grenier, L.; Laguee, P.; Sauter, C.; Sissler, M.; Giege, R.; Lapointe, J.; Florentz, C.
Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs
Biochimie
91
596-603
2009
Bos taurus, Escherichia coli, Homo sapiens, Pseudomonas aeruginosa
Charriere, F.; ODonoghue, P.; Helgadottir, S.; Marechal-Drouard, L.; Cristodero, M.; Horn, E.K.; Soell, D.; Schneider, A.
Dual targeting of a tRNAAsp requires two different aspartyl-tRNA synthetases in Trypanosoma brucei
J. Biol. Chem.
284
16210-16217
2009
Trypanosoma brucei (Q38CB4), Trypanosoma brucei (Q585M3), Trypanosoma brucei
Bour, T.; Akaddar, A.; Lorber, B.; Blais, S.; Balg, C.; Candolfi, E.; Frugier, M.
Plasmodial aspartyl-tRNA synthetases and peculiarities in Plasmodium falciparum
J. Biol. Chem.
284
18893-18903
2009
Homo sapiens, Plasmodium falciparum (Q8I2B1), Plasmodium falciparum, Saccharomyces cerevisiae
Ul-Haq, Z.; Khan, W.; Zarina, S.; Sattar, R.; Moin, S.T.
Template-based structure prediction and molecular dynamics simulation study of two mammalian aspartyl-tRNA synthetases
J. Mol. Graph. Model.
28
401-412
2010
Homo sapiens (P14868), Homo sapiens, Mus musculus (Q922B2), Mus musculus
Merritt, E.A.; Arakaki, T.L.; Larson, E.T.; Kelley, A.; Mueller, N.; Napuli, A.J.; Zhang, L.; Deditta, G.; Luft, J.; Verlinde, C.L.; Fan, E.; Zucker, F.; Buckner, F.S.; Van Voorhis, W.C.; Hol, W.G.
Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica
Mol. Biochem. Parasitol.
169
95-100
2010
Entamoeba histolytica (C4LZN0), Entamoeba histolytica
Messmer, M.; Florentz, C.; Schwenzer, H.; Scheper, G.C.; van der Knaap, M.S.; Marechal-Drouard, L.; Sissler, M.
A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria
Biochem. J.
433
441-446
2011
Homo sapiens (Q6PI48), Homo sapiens
Imanaka, T.; Lee, S.; Takagi, M.; Fujiwara, S.
Aspartyl-tRNA synthetase of the hyperthermophilic archaeon Pyrococcus sp. KOD1 has a chimerical structure of eukaryotic and bacterial enzymes
Gene
164
153-156
1995
Thermococcus kodakarensis (Q52428)
van Berge, L.; Kevenaar, J.; Polder, E.; Gaudry, A.; Florentz, C.; Sissler, M.; van der Knaap, M.S.; Scheper, G.C.
Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways
Biochem. J.
450
345-350
2013
Homo sapiens (Q6PI48), Homo sapiens
Kron, M.A.; Metwali, A.; Vodanovic-Jankovic, S.; Elliott, D.
Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis
Clin. Vaccine Immunol.
20
276-281
2013
Brugia malayi
Neuenfeldt, A.; Lorber, B.; Ennifar, E.; Gaudry, A.; Sauter, C.; Sissler, M.; Florentz, C.
Thermodynamic properties distinguish human mitochondrial aspartyl-tRNA synthetase from bacterial homolog with same 3D architecture
Nucleic Acids Res.
41
2698-2708
2013
Escherichia coli, Homo sapiens (Q6PI48), Homo sapiens
Fuengfuloy, P.; Chuawong, P.; Suebka, S.; Wattana-Amorn, P.; Williams, C.; Crump, M.P.; Songsiriritthigul, C.
Overproduction of the N-terminal anticodon-binding domain of the non-discriminating aspartyl-tRNA synthetase from Helicobacter pylori for crystallization and NMR measurements
Protein Expr. Purif.
89
25-32
2013
Helicobacter pylori
Kim, K.R.; Park, S.H.; Kim, H.S.; Rhee, K.H.; Kim, B.G.; Kim, D.G.; Park, M.S.; Kim, H.J.; Kim, S.; Han, B.W.
Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex
Proteins
81
1840-1846
2013
Homo sapiens (P14868), Homo sapiens
Songsiriritthigul, C.; Suebka, S.; Chen, C.J.; Fuengfuloy, P.; Chuawong, P.
Crystal structure of the N-terminal anticodon-binding domain of the nondiscriminating aspartyl-tRNA synthetase from Helicobacter pylori
Acta Crystallogr. Sect. F
73
62-69
2017
Helicobacter pylori (P56459), Helicobacter pylori ATCC 700392 (P56459)
Schwenzer, H.; Scheper, G.; Zorn, N.; Moulinier, L.; Gaudry, A.; Leize, E.; Martin, F.; Florentz, C.; Poch, O.; Sissler, M.
Released selective pressure on a structural domain gives new insights on the functional relaxation of mitochondrial aspartyl-tRNA synthetase
Biochimie
100
18-26
2014
Homo sapiens, Mus musculus
Nair, N.; Raff, H.; Islam, M.T.; Feen, M.; Garofalo, D.M.; Sheppard, K.
The Bacillus subtilis and Bacillus halodurans aspartyl-tRNA synthetases retain recognition of tRNAAsn
J. Mol. Biol.
428
618-630
2016
Mycoplasma pneumoniae
Luna, E.; van Hulten, M.; Zhang, Y.; Berkowitz, O.; Lopez, A.; Petriacq, P.; Sellwood, M.A.; Chen, B.; Burrell, M.; van de Meene, A.; Pieterse, C.M.; Flors, V.; Ton, J.
Plant perception of gamma-aminobutyric acid is mediated by an aspartyl-tRNA synthetase
Nat. Chem. Biol.
10
450-456
2014
Arabidopsis thaliana
Gurcha, S.S.; Usha, V.; Cox, J.A.; Fuetterer, K.; Abrahams, K.A.; Bhatt, A.; Alderwick, L.J.; Reynolds, R.C.; Loman, N.J.; Nataraj, V.; Alemparte, C.; Barros, D.; Lloyd, A.J.; Ballell, L.; Hobrath, J.V.; Besra, G.S.
Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target
PLoS ONE
9
e113568
2014
Mycolicibacterium smegmatis, Mycobacterium tuberculosis (P9WFW3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WFW3)
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