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Information on EC 5.4.99.61 - precorrin-8X methylmutase and Organism(s) Sinorhizobium sp and UniProt Accession P21638

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.61 precorrin-8X methylmutase
IUBMB Comments
The enzyme, which participates in the aerobic (late cobalt insertion) adenosylcobalamin biosynthesis pathway, catalyses the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement. The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60, cobalt-precorrin-8 methylmutase.
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This record set is specific for:
Sinorhizobium sp
UNIPROT: P21638
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
precorrin isomerase, precorrin-8x methylmutase, hydrogenobyrinic acid-binding protein, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
GenBank AE000809-derived protein GI 2621284
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GenBank U67537-derived protein GI 1499765
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Gene cbiC precorrin-8x isomerase
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Gene cobH precorrin-8x isomerase
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Hydrogenobyrinic acid-binding protein
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Isomerase, precorrin (Methanobacterium thermoautothrophicum strain DELTAH gene MTH227)
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Isomerase, precorrin (Methanococcus jannaschii gene MJ0930)
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Mutase, precorrin 8x
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Precorrin isomerase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
isomerization
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
precorrin-8X 11,12-methylmutase
The enzyme, which participates in the aerobic (late cobalt insertion) adenosylcobalamin biosynthesis pathway, catalyses the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement. The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60, cobalt-precorrin-8 methylmutase.
CAS REGISTRY NUMBER
COMMENTARY hide
138238-71-8
gene cbiC precorrin-8x isomerase /gene cobH precorrin-8x isomerase
181967-26-0
isomerase, precorrin (Methanococcus jannaschii gene MJ0930) / genBank U67537-derived protein GI 1499765
198584-26-8
isomerase, precorrin (Methanobacterium thermoautothrophicum strain DELTAH gene MTH227) /genBank AE00809-derived protein GI 2621284
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
COBH_SINSX
Sinorhizobium sp
210
0
22064
Swiss-Prot
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