Information on EC 5.4.99.57 - baruol synthase

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The expected taxonomic range for this enzyme is: Arabidopsis thaliana

EC NUMBER
COMMENTARY hide
5.4.99.57
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RECOMMENDED NAME
GeneOntology No.
baruol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(3S)-2,3-epoxy-2,3-dihydrosqualene = baruol
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
baruol biosynthesis
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Sesquiterpenoid and triterpenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baruol-forming)
The enzyme from Arabidopsis thaliana also produces traces of 22 other triterpenoids.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene
baruol
show the reaction diagram
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major product baruol (90%) and 22 minor products (0.02-3% each) which are columbiol, sasanqual, dammara-20,24-dienol, podioda-7,17,21-trienol, delta-amyrin, malabarica-14(27),17,21-trienol, isomultiflorenol, achilleol A, lemmaphylladienol, taraxerol, isoturicallol, camelliol C, taraxasterol, psi-taraxasterol, lupeol, beta-amyrin, multifluorenol, alpha-amyrin, butyrospermol, tirucalla-7,24-dienol and an unidentified DELTA5 triterpene
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE