Information on EC 5.4.99.53 - marneral synthase

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The expected taxonomic range for this enzyme is: Arabidopsis thaliana

EC NUMBER
COMMENTARY hide
5.4.99.53
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RECOMMENDED NAME
GeneOntology No.
marneral synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(3S)-2,3-epoxy-2,3-dihydrosqualene = marneral
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Biosynthesis of secondary metabolites
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marneral biosynthesis
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Sesquiterpenoid and triterpenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, marneral-forming)
Marneral is a triterpenoid formed by Grob fragmentation of the A ring of 2,3-epoxy-2,3-dihydrosqualene during cyclization.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
an Arabidopsis mrn1 knock-out mutant shows round-shaped leaves and late flowering is isolated under long-day conditions. The late-flowering phenotype is much more severe under short-day conditions than under longday conditions. The mrn1 mutant displays aberrant seed morphology, a low germination rate, and root growth retardation. Mrn1 mutant shows a delayed embryo development
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene
marneral
show the reaction diagram
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?
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
MRN1 gene is specifically expressed in shoot and root apical meristems and induced by osmotic stress and abscisic acid
Manually annotated by BRENDA team
MRN1 gene is specifically expressed in shoot and root apical meristems and induced by osmotic stress and abscisic acid
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
MRN1 gene is specifically expressed in shoot and root apical meristems and is induced by osmotic stress and abscisic acid