Information on EC 5.4.99.43 - 21S rRNA pseudouridine2819 synthase

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The expected taxonomic range for this enzyme is: Saccharomyces cerevisiae

EC NUMBER
COMMENTARY hide
5.4.99.43
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RECOMMENDED NAME
GeneOntology No.
21S rRNA pseudouridine2819 synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
21S rRNA uridine2819 = 21S rRNA pseudouridine2819
show the reaction diagram
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SYSTEMATIC NAME
IUBMB Comments
21S rRNA-uridine2819 uracil mutase
The enzyme specifically acts on uridine2819 in 21S rRNA.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
21S rRNA uridine2819
21S rRNA pseudouridine2819
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
21S rRNA uridine2819
21S rRNA pseudouridine2819
show the reaction diagram
Q06244
pseudouridine2819 in mitochondrial 21S rRNA is not essential for cell viability
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?
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
the selective uridine-pseudouridine conversion at position 2819 in mitochondrial 21S rRNA is restored when the deleted yeast strain is transformed by a plasmid expressing the wild-type YLR165c ORF
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D71A
inactive mutant enzyme