Information on EC 5.4.99.26 - tRNA pseudouridine65 synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Escherichia coli

EC NUMBER
COMMENTARY hide
5.4.99.26
-
RECOMMENDED NAME
GeneOntology No.
tRNA pseudouridine65 synthase
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
tRNA uridine65 = tRNA pseudouridine65
show the reaction diagram
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
tRNA-uridine65 uracil mutase
TruC specifically modifies uridines at positions 65 in tRNA.
CAS REGISTRY NUMBER
COMMENTARY hide
430429-15-5
-
61506-89-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
pseudouridine sequencing of the relevant tRNAs isolated from a strain in which yqcB is deleted shows that YqcB is the synthase specific for C65 in tRNAAsp and tRNAIle1
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
tRNA uridine65
tRNA pseudouridine65
show the reaction diagram
-
pseudouridine sequencing of the relevant tRNAs isolated from a strain in which yqcB is deleted shows that YqcB specifically forms pseudouridine65 in tRNAAsp and tRNAIle1
-
-
?
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D54T
-
inactive mutant enzyme
Show AA Sequence (282 entries)
Please use the Sequence Search for a specific query.