Reference on EC 5.4.2.8 - phosphomannomutase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Jaeken, J.; Pirard, M.; Adamowicz, M.; Pronicka, E.; van Schaftingen, E.
Inhibition of phosphomannose isomerase by fructose 1-phosphate: an explanation for defective N-glycosylation in hereditary fructose intolerance
Pediatr. Res.
40
764-766
1996
Homo sapiens
Small, D.M.; Matheson, N.K.
Phosphomannomutase and phosphoglucomutase in developing Cassia corymbosa seeds
Phytochemistry
18
1147-1150
1979
Cassia corymbosa
-
Glaser, L.
Phosphomannomutase from yeast
Methods Enzymol.
8
183-185
1966
Saccharomyces cerevisiae
-
Murata, T.
Purification and some properties of phosphomannomutase from corms of Amorphophallus konjac C. Koch
Plant Cell Physiol.
17
1099-1109
1976
Amorphophallus konjac
-
Guha, S.K.; Rose, Z.B.
The synthesis of mannose 1-phosphate in brain
Arch. Biochem. Biophys.
243
168-173
1985
Oryctolagus cuniculus
Padgett, P.J.; Phibbs, P.V.
Phosphomannomutase activity in wild-type and alginate-producing strains of Pseudomonas aeruginosa
Curr. Microbiol.
14
187-192
1986
Pseudomonas aeruginosa
-
Sa-Correia, I.; Darzins, A.; Wang, S.K.; Berry, A.; Chakrabarty, A.M.
Alginate biosynthetic enzymes in mucoid and nonmucoid Pseudomonas aeruginosa: overproduction of phosphomannose isomerase, phosphomannomutase, and GDP-mannose pyrophosphorylase by overexpression of the phosphomannose isomerase (pmi) gene
J. Bacteriol.
169
3224-3231
1987
Pseudomonas aeruginosa
Kepes, F.; Schekman, R.
The yeast SEC53 gene encodes phosphomannomutase
J. Biol. Chem.
263
9155-9161
1988
Saccharomyces cerevisiae
Hansen, S.H.; Frank, S.R.; Casanova, J.E.
Cloning and characterization of human phosphomannomutase, a mammalian homologue of yeast SEC53
Glycobiology
7
829-834
1997
Homo sapiens
Elling, L.; Ritter, J.E.; Verseck, S.
Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose
Glycobiology
6
591-597
1996
Salmonella enterica
Goldberg, J.B.; Hatano, K.; Pier, G.B.
Synthesis of lipopolysaccharide O side chains by Pseudomonas aeruginosa PAO1 requires the enzyme phosphomannomutase
J. Bacteriol.
175
1605-1611
1993
Pseudomonas aeruginosa
Pirard, M.; Collet, J.F.; Matthijs, G.; van Schaftingen, E.
Comparison of PMM1 with the phosphomannomutases expressed in rat liver and in human cells
FEBS Lett.
411
251-254
1997
Homo sapiens, Rattus norvegicus
Oesterhelt, C.; Schnarrenberger, C.; Gross, W.
The reaction mechanism of phosphomannomutase in plants
FEBS Lett.
401
35-37
1997
Galdieria sulphuraria, Embryophyta, Mammalia
Zielinski, N.A.; Chakrabarty, A.M.; Berry, A.
Characterization and regulation of the Pseudomonas aeruginosa algC gene encoding phosphomannomutase
J. Biol. Chem.
266
9754-9763
1991
Pseudomonas aeruginosa
Regni, C.A.; Tipton, P.A.; Beamer, L.J.
Crystallization and initial crystallographic analysis of phosphomannomutase/phosphoglucomutase from Pseudomonas aeruginosa
Acta Crystallogr. Sect. D
56
761-762
2000
Pseudomonas aeruginosa
Naught, L.E.; Tipton, P.A.
Kinetic mechanism and pH dependence of the kinetic parameters of Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase
Arch. Biochem. Biophys.
396
111-118
2001
Pseudomonas aeruginosa
Pirard, M.; Achouri, Y.; Collet, J.F.; Schollen, E.; Matthijs, G.; Van Schaftingen, E.
Kinetic properties and tissular distribution of mammalian phosphomannomutase isozymes
Biochem. J.
339
201-207
1999
Homo sapiens, Rattus norvegicus
-
Popova, T.N.; Matasova, L.V.; Lapot'ko, A.A.
Purification, separation and characterization of phosphoglucomutase and phosphomannomutase from maize leaves
Biochem. Mol. Biol. Int.
46
461-470
1998
Zea mays
Naught, L.E.; Regni, C.; Beamer, L.J.; Tipton, P.A.
Roles of active site residues in Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase
Biochemistry
42
9946-9951
2003
Pseudomonas aeruginosa (P26276)
Regni, C.; Tipton, P.A.; Beamer, L.J.
Crystal Structure of PMM/PGM: An Enzyme in the Biosynthetic Pathway of P. aeruginosa Virulence Factors
Structure
10
269-279
2002
Pseudomonas aeruginosa (P26276)
Menniti, M.; Iuliano, R.; Amato, R.; Boito, R.; Corea, M.; Le Pera, I.; Gulletta, E.; Fuiano, G.; Perrotti, N.
Serum and glucocorticoid-regulated kinase Sgk1 inhibits insulin-dependent activation of phosphomannomutase 2 in transfected COS-7 cells
Am. J. Physiol.
288
C148-155
2005
Homo sapiens
Liu, H.Y.; Wang, Z.; Regni, C.; Zou, X.; Tipton, P.A.
Detailed kinetic studies of an aggregating inhibitor; inhibition of phosphomannomutase/phosphoglucomutase by disperse blue 56
Biochemistry
43
8662-8669
2004
Pseudomonas aeruginosa
Rashid, N.; Kanai, T.; Atomi, H.; Imanaka, T.
Among multiple phosphomannomutase gene orthologues, only one gene encodes a protein with phosphoglucomutase and phosphomannomutase activities in Thermococcus kodakaraensis
J. Bacteriol.
186
6070-6076
2004
Thermococcus kodakarensis
Akutsu, J.; Zhang, Z.; Tsujimura, M.; Sasaki, M.; Yohda, M.; Kawarabayasi, Y.
Characterization of a thermostable enzyme with phosphomannomutase/phosphoglucomutase activities from the hyperthermophilic archaeon Pyrococcus horikoshii OT3
J. Biochem.
138
159-166
2005
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
Regni, C.; Shackelford, G.S.; Beamer, L.J.
Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor
Acta Crystallogr. Sect. F
F62
722-726
2006
Pseudomonas aeruginosa
Ray, W.K.; Keith, S.M.; DeSantis, A.M.; Hunt, J.P.; Larson, T.J.; Helm, R.F.; Kennelly, P.J.
A phosphohexomutase from the archaeon Sulfolobus solfataricus is covalently modified by phosphorylation on serine
J. Bacteriol.
187
4270-4275
2005
Saccharolobus solfataricus (Q980S1), Saccharolobus solfataricus P2 (Q980S1)
Silvaggi, N.R.; Zhang, C.; Lu, Z.; Dai, J.; Dunaway-Mariano, D.; Allen, K.N.
The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a
J. Biol. Chem.
281
14918-14926
2006
Homo sapiens (O15305), Homo sapiens (Q92871)
Regni, C.; Schramm, A.M.; Beamer, L.J.
The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme
J. Biol. Chem.
281
15564-15571
2006
Pseudomonas aeruginosa
Kedzierski, L.; Malby, R.L.; Smith, B.J.; Perugini, M.A.; Hodder, A.N.; Ilg, T.; Colman, P.M.; Handman, E.
Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms
J. Mol. Biol.
363
215-227
2006
Homo sapiens, Leishmania mexicana (Q95ZD7), Leishmania mexicana
Qian, W.; Yu, C.; Qin, H.; Liu, X.; Zhang, A.; Johansen, I.E.; Wang, D.
Molecular and functional analysis of phosphomannomutase (PMM) from higher plants and genetic evidence for the involvement of PMM in ascorbic acid biosynthesis in Arabidopsis and Nicotiana benthamiana
Plant J.
49
399-413
2007
Nicotiana benthamiana, Arabidopsis thaliana (O80840)
Schramm, A.M.; Mehra-Chaudhary, R.; Furdui, C.M.; Beamer, L.J.
Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa
Biochemistry
47
9154-9162
2008
Pseudomonas aeruginosa (P26276)
Yoon, S.; Park, S.; Kim, Y.; Shin, M.; Chong, C.; Choi, J.
Cloning and characterization of phosphoglucomutase and phosphomannomutase derived from Sphingomonas chungbukensis DJ77
J. Biochem.
144
507-512
2008
Sphingobium chungbukense, Sphingobium chungbukense DJ77
Veiga-da-Cunha, M.; Vleugels, W.; Maliekal, P.; Matthijs, G.; Van Schaftingen, E.
Mammalian phosphomannomutase PMM1 is the brain IMP-sensitive glucose-1,6-bisphosphatase
J. Biol. Chem.
283
33988-33993
2008
Mus musculus
Hoeberichts, F.A.; Vaeck, E.; Kiddle, G.; Coppens, E.; van de Cotte, B.; Adamantidis, A.; Ormenese, S.; Foyer, C.H.; Zabeau, M.; Inze, D.; Perilleux, C.; Van Breusegem, F.; Vuylsteke, M.
A temperature-sensitive mutation in the Arabidopsis thaliana phosphomannomutase gene disrupts protein glycosylation and triggers cell death
J. Biol. Chem.
283
5708-5718
2008
Arabidopsis thaliana
Nic Lochlainn, L.; Caffrey, P.
Phosphomannose isomerase and phosphomannomutase gene disruptions in Streptomyces nodosus: impact on amphotericin biosynthesis and implications for glycosylation engineering
Metab. Eng.
11
40-47
2009
Streptomyces nodosus (B6Z254), Streptomyces nodosus
Badejo, A.A.; Eltelib, H.A.; Fukunaga, K.; Fujikawa, Y.; Esaka, M.
Increase in ascorbate content of transgenic tobacco plants overexpressing acerola (Malpighia glabra) phosphomannomutase gene
Plant Cell Physiol.
50
423-428
2009
Malpighia glabra (C0JP35), Malpighia glabra
Siddique, S.; Endres, S.; Atkins, J.M.; Szakasits, D.; Wieczorek, K.; Hofmann, J.; Blaukopf, C.; Urwin, P.E.; Tenhaken, R.; Grundler, F.M.; Kreil, D.P.; Bohlmann, H.
Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
184
457-472
2009
Arabidopsis thaliana (O80840)
Yang, Y.H.; Song, E.; Park, S.H.; Kim, J.N.; Lee, K.; Kim, E.; Kim, Y.G.; Kim, B.G.
Loss of phosphomannomutase activity enhances actinorhodin production in Streptomyces coelicolor
Appl. Microbiol. Biotechnol.
86
1485-1492
2010
Streptomyces coelicolor (Q9KZL6), Streptomyces coelicolor
Yang, Y.; Kang, Y.; Kim, D.; Lee, T.; Park, S.; Lee, K.; Yoo, D.; Liou, K.; Lee, H.; Sohng, J.; Kim, B.
One-pot enzymatic synthesis of deoxy-thymidine-diphosphate (TDP)-2-deoxy-alpha-D-glucose using phosphomannomutase
J. Mol. Catal. B
62
282-287
2010
Escherichia coli K-12
-
Higashidani, A.; Bode, L.; Nishikawa, A.; Freeze, H.H.
Exogenous mannose does not raise steady state mannose-6-phosphate pools of normal or N-glycosylation-deficient human fibroblasts
Mol. Genet. Metab.
96
268-272
2009
Homo sapiens, Mus musculus
Yu, C.; Li, Y.; Li, B.; Liu, X.; Hao, L.; Chen, J.; Qian, W.; Li, S.; Wang, G.; Bai, S.; Ye, H.; Qin, H.; Shen, Q.; Chen, L.; Zhang, A.; Wang, D.
Molecular analysis of phosphomannomutase (PMM) genes reveals a unique PMM duplication event in diverse Triticeae species and the main PMM isozymes in bread wheat tissues
BMC Plant Biol.
10
214
2010
Hordeum vulgare, Oryza sativa, Triticum turgidum subsp. durum, Triticum turgidum subsp. durum (C8CK11), Triticum turgidum subsp. durum (C8CK12), Triticum turgidum subsp. durum (C8CK13), Triticum urartu, Brachypodium distachyon, Triticum aestivum (C8CK06), Triticum aestivum (C8CK09), Triticum aestivum (C8CK10), Triticum aestivum, Aegilops tauschii (C8CK15), Aegilops tauschii (C8CK16)
Mitra, S.; Cui, J.; Robbins, P.W.; Samuelson, J.
A deeply divergent phosphoglucomutase (PGM) of Giardia lamblia has both PGM and phosphomannomutase activities
Glycobiology
20
1233-1240
2010
Giardia intestinalis
Vega, A.I.; Perez-Cerda, C.; Abia, D.; Gamez, A.; Briones, P.; Artuch, R.; Desviat, L.R.; Ugarte, M.; Perez, B.
Expression analysis revealing destabilizing mutations in phosphomannomutase 2 deficiency (PMM2-CDG): Expression analysis of PMM2-CDG mutations
J. Inherit. Metab. Dis.
34
929-939
2011
Homo sapiens (O15305), Homo sapiens
Chu, H.Y.; Zheng, Q.C.; Li, X.; Zhao, Y.S.; Zhang, J.L.; Zhang, H.X.
DFT investigation on the reaction mechanism catalyzed by alpha-phosphomannomutase1 in protonated/deprotonated states
J. Mol. Model.
17
577-585
2011
Homo sapiens (Q92871)
Huang, H.; Li, X.; Wu, M.; Wang, S.; Li, G.; Ma, T.
Cloning, expression and characterization of a phosphoglucomutase/phosphomannomutase from sphingan-producing Sphingomonas sanxanigenens
Biotechnol. Lett.
35
1265-1270
2013
Sphingomonas sanxanigenens (M1T754), Sphingomonas sanxanigenens, Sphingomonas sanxanigenens NX02 (M1T754)
Lee, Y.; Villar, M.T.; Artigues, A.; Beamer, L.J.
Promotion of enzyme flexibility by dephosphorylation and coupling to the catalytic mechanism of a phosphohexomutase
J. Biol. Chem.
289
4674-4682
2014
Pseudomonas aeruginosa
Bandini, G.; Marino, K.; Guether, M.L.; Wernimont, A.K.; Kuettel, S.; Qiu, W.; Afzal, S.; Kelner, A.; Hui, R.; Ferguson, M.A.
Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase
Mol. Microbiol.
85
513-534
2012
Trypanosoma brucei (F4NCC2), Trypanosoma brucei, Trypanosoma brucei 427 (F4NCC2)
Ji, T.; Zhang, C.; Zheng, L.; Dunaway-Mariano, D.; Allen, K.N.
Structural basis of the molecular switch between phosphatase and mutase functions of human phosphomannomutase 1 under ischemic conditions
Biochemistry
57
3480-3492
2018
Homo sapiens (O15305), Homo sapiens
Andreotti, G.; Cabeza de Vaca, I.; Poziello, A.; Monti, M.C.; Guallar, V.; Cubellis, M.V.
Conformational response to ligand binding in phosphomannomutase2 insights into inborn glycosylation disorder
J. Biol. Chem.
289
34900-34910
2014
Homo sapiens (O15305), Homo sapiens
Oh, R.; Moon, S.; Cho, H.; Jang, W.; Kim, J.; Lee, J.; Kong, I.
Cloning and characterization of phosphomannomutase/phosphoglucomutase (pmm/pgm) gene of Vibrio anguillarum related to synthesis of LPS
Microbiol. Biotechnol. Lett.
44
355-362
2016
Vibrio anguillarum, Vibrio anguillarum O1
-
Kaur, T.; Ghosh, M.
Characterization and upregulation of bifunctional phosphoglucomutase/phosphomannomutase enzyme in an exobiopolymer overproducing strain of Acinetobacter haemolyticus
Microbiol. Res.
181
8-14
2015
Acinetobacter haemolyticus
Andreotti, G.; Monti, M.C.; Citro, V.; Cubellis, M.V.
Heterodimerization of two pathological mutants enhances the activity of human phosphomannomutase2
PLoS ONE
10
e0139882
2015
Homo sapiens (O15305), Homo sapiens
Citro, V.; Cimmaruta, C.; Liguori, L.; Viscido, G.; Cubellis, M.V.; Andreotti, G.
A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP Possible implications for the disease PMM2-CDG
PLoS ONE
12
e0189629
2017
Homo sapiens (O15305), Homo sapiens (Q92871), Homo sapiens
He, C.; Zeng, S.; Teixeira da Silva, J.A.; Yu, Z.; Tan, J.; Duan, J.
Molecular cloning and functional analysis of the phosphomannomutase (PMM) gene from Dendrobium officinale and evidence for the involvement of an abiotic stress response during germination
Protoplasma
254
1693-1704
2017
Dendrobium officinale (A0A0U1WZ18), Dendrobium officinale
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