Information on EC 5.3.99.9 - neoxanthin synthase

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The expected taxonomic range for this enzyme is: asterids

EC NUMBER
COMMENTARY
5.3.99.9
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RECOMMENDED NAME
GeneOntology No.
neoxanthin synthase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
violaxanthin = neoxanthin
show the reaction diagram
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-
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PATHWAY
KEGG Link
MetaCyc Link
abscisic acid biosynthesis
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neoxanthin biosynthesis
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Carotenoid biosynthesis
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Metabolic pathways
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Biosynthesis of secondary metabolites
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SYSTEMATIC NAME
IUBMB Comments
violaxanthin---neoxanthin isomerase (epoxide-opening)
The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
CAS REGISTRY NUMBER
COMMENTARY
318960-21-3
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
genotypes VRT-32-1, EC-521086, and red stage genotype EC-521086
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Manually annotated by BRENDA team
L. cv. Phillippino
SwissProt
Manually annotated by BRENDA team
plants growing naturally in a forest in Oulu, Finland
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-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
metabolism
-
the gene encoding the enzyme is involved in catabolism of lycopene into different carotenoids
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
violaxanthin
neoxanthin
show the reaction diagram
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-
-
-
?
violaxanthin
neoxanthin
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
violaxanthin
neoxanthin
show the reaction diagram
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-
-
-
?
violaxanthin
neoxanthin
show the reaction diagram
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-
-
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?
SOURCE TISSUE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE
Q9LWA6, -
mature green, pink and red
Manually annotated by BRENDA team
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high expression level in berries, expression increases markedly at the onset of berry ripening along with the accumulation of abscisic acid. Quantitative real-time PCR enzyme expression analysis during fruit development
Manually annotated by BRENDA team
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gene NXS is expressed at relatively lower level at breaker and red-ripe stages in genotype EC-521086
Manually annotated by BRENDA team
additional information
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gene NXS expression analysis in different genotypes, overview
Manually annotated by BRENDA team
Cloned/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
expression in Escherichia coli or transfection of Nicotiana benthamiana leaves
Q9LWA6, -
gene NXS, expression analysis in different genotypes, overview
-
plant protoplasts obtained from Arabidopsis thaliana tissue culture and Nicotiana tabacum leaves are transformed with the full length cDNA under control of the 35S CaMV promoter by electroporation and PEG
Q9M424, -
gene VmNSY, DNA and amino acid sequence determination and analysis, sequence comparisons
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EXPRESSION
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
gene NXS is downregulated at red stage of fruit ripening in red stage genotype EC-521086
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