Information on EC 5.3.99.9 - neoxanthin synthase

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The expected taxonomic range for this enzyme is: asterids

EC NUMBER
COMMENTARY hide
5.3.99.9
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RECOMMENDED NAME
GeneOntology No.
neoxanthin synthase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
violaxanthin = neoxanthin
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
abscisic acid biosynthesis
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Biosynthesis of secondary metabolites
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Carotenoid biosynthesis
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Metabolic pathways
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neoxanthin biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
violaxanthin---neoxanthin isomerase (epoxide-opening)
The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].
CAS REGISTRY NUMBER
COMMENTARY hide
318960-21-3
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Uniprot
Manually annotated by BRENDA team
plants growing naturally in a forest in Oulu, Finland
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
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the gene encoding the enzyme is involved in catabolism of lycopene into different carotenoids
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
violaxanthin
neoxanthin
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
violaxanthin
neoxanthin
show the reaction diagram
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
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gene NXS expression analysis in different genotypes, overview
Manually annotated by BRENDA team
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli or transfection of Nicotiana benthamiana leaves
gene NXS, expression analysis in different genotypes, overview
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gene VmNSY, DNA and amino acid sequence determination and analysis, sequence comparisons
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plant protoplasts obtained from Arabidopsis thaliana tissue culture and Nicotiana tabacum leaves are transformed with the full length cDNA under control of the 35S CaMV promoter by electroporation and PEG
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
gene NXS is downregulated at red stage of fruit ripening in red stage genotype EC-521086
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