Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 5.3.3.8 - DELTA3-DELTA2-enoyl-CoA isomerase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Pawar, S.; Schulz, H.
The structure of the multienzyme complex of fatty acid oxidation from Escherichia coli
J. Biol. Chem.
256
3894-3899
1981
Escherichia coli
Manually annotated by BRENDA team
Yang, S.Y.; Li, J.; He, X.Y.; Cosloy, S.D.; Schulz, H.
Evidence that the fadB gene of the fadAB operon of Escherichia coli encodes 3-hydroxyacyl-coenzyme A (CoA) epimerase, DELTA3-cis-DELTA2-trans-enoyl-CoA isomerase, and enoyl-CoA hydratase in addition to 3-hydroxyacyl-CoA dehydrogenase
J. Bacteriol.
170
2543-2548
1988
Escherichia coli
Manually annotated by BRENDA team
Yokota, S.; Tomioka, Y.; Suzuki, H.; Mizugaki, M.
Immunocytochemical localization of DELTA3,DELTA2-enoyl-CoA isomerase and NADPH-dependent-2,4-dienoyl-CoA reductase in rat kidney
Histochemistry
99
463-469
1993
Rattus norvegicus
Manually annotated by BRENDA team
Stoffel, W.; Ecker, W.
DELTA3-cis,DELTA2-trans-Enoyl-CoA isomerase from rat liver mitochondria
Methods Enzymol.
14
99-105
1979
Rattus norvegicus
-
Manually annotated by BRENDA team
Miscowicz, F.M.; Bloch, K.
Purification of hog liver isomerase. Mechanism of isomerization of 3-alkenyl and 3-alkynyl thioesters
J. Biol. Chem.
254
5868-5877
1979
Sus scrofa
Manually annotated by BRENDA team
Stoffel, W.; Grol, M.
Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenyl-CoA DELTA-isomerase) from rat liver mitochondria
Hoppe-Seyler's Z. Physiol. Chem.
359
1777-1782
1978
Rattus norvegicus
Manually annotated by BRENDA team
Lawson, L.D.; Holman, R.T.
beta-Oxidation of the geometric and positional isomers of octadecenoic acid by rat heart and liver mitochondria
Biochim. Biophys. Acta
665
60-65
1981
Rattus norvegicus
Manually annotated by BRENDA team
Miernyk, J.A.; Trelease, R.N.
Control of enzyme activities in cotton cotyledons during maturation and germination
Plant Physiol.
67
341-346
1981
Gossypium hirsutum
Manually annotated by BRENDA team
Spratt, S.K.; Black, P.N.; Ragozzino, M.M.; Nunn, W.D.
Cloning, mapping, and expression of genes involved in the fatty acid-degradative multienzyme complex of Escherichia coli
J. Bacteriol.
158
535-542
1984
Escherichia coli
Manually annotated by BRENDA team
Krki,T.; Hakkola, E.; Hassinen, I.E.; Hiltunen, J.K.
beta-Oxidation of polyunsaturated fatty acids in peroxisomes. Subcellular distribution of delta3,delta2-enoyl-CoA isomerase activity in rat liver
FEBS Lett.
215
228-232
1987
Rattus norvegicus
Manually annotated by BRENDA team
Behrends, W.; Thieringer, R.; Engeland, K.; Kunau, W.H.; Kindl, H.
The glycosomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids
Arch. Biochem. Biophys.
263
170-177
1988
Cucumis sativus
Manually annotated by BRENDA team
Tomioka, Y.; Aihara, K.; Hirose, A.; Hishinuma, T.; Mizugaki, M.
Detection of heat-stable DELTA3,DELTA2-enoyl-CoA isomerase in rat liver mitochondria and peroxisomes by immunochemical study using specific antibody
J. Biochem.
109
394-398
1991
Rattus norvegicus
Manually annotated by BRENDA team
Muller-Newen, G.; Stoffel, W.
Mitochondrial 3-2trans-enoyl-CoA isomerase. Purification, cloning, expression, and mitochondrial import of the key enzyme of unsaturated fatty acid beta-oxidation
Biol. Chem. Hoppe-Seyler
372
613-624
1991
Rattus norvegicus
Manually annotated by BRENDA team
Euler-Bertram, S.; Stoffel, W.
Purification and characterization of bovine liver 3-cis-2-trans-enoyl-CoA isomerase
Biol. Chem. Hoppe-Seyler
371
603-610
1990
Bos taurus, Sus scrofa
Manually annotated by BRENDA team
Stark, A.; Meijer, J.
Purification and characterization of a multifunctional enzyme from mouse liver peroxisomes
Comp. Biochem. Physiol. B
108
471-480
1994
Mus musculus
Manually annotated by BRENDA team
Yang, S.Y.; He, X.Y.; Schulz, H.
Glutamate 139 of the large alpha-subunit is the catalytic base in the dehydration of both D- and L-3-hydroxyacyl-coenzyme A but not in the isomerization of DELTA3,DELTA2-enoyl-coenzyme A catalyzed by the multienzyme complex of fatty acid oxidation from Escherichia coli
Biochemistry
34
6441-6447
1995
Escherichia coli
Manually annotated by BRENDA team
Tomioka, Y.; Hirose, A.; Moritani, H.; Hishinuma, T.; Hashimoto, T.; Mizugaki, M.
cDNA cloning of mitochondrial delta3,delta2-enoyl-CoA isomerase of rat liver
Biochim. Biophys. Acta
1130
109-112
1992
Rattus norvegicus
Manually annotated by BRENDA team
Palossari, P.M.; Kilponen, J.M.; Sormunen, R.T.; Hassinen, I.E.; Hiltunen, J.K.
DELTA3,DELTA2-Enoyl-CoA isomerases. Characterization of the mitochondrial isoenzyme in the rat
J. Biol. Chem.
265
3347-3353
1990
Bos taurus, Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Palossari, P.M.; Hiltunen, J.K.
Peroxisomal bifunctional protein from rat liver is a trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and DELTA3,DELTA2-enoyl-CoA isomerase activities
J. Biol. Chem.
265
2446-2449
1990
Rattus norvegicus
Manually annotated by BRENDA team
Kilponen, J.M.; Hyrinen, H.M.; Rehn, M.; Hiltunen, J.K.
cDNA cloning and amino acid sequence of human mitochondrial DELTA3DELTA2-enoyl-CoA isomerase: comparison of the human enzyme with its rat counterpart, mitochondrial short-chain isomerase
Biochem. J.
300
1-5
1994
Homo sapiens
Manually annotated by BRENDA team
Takahashi, Y.; Hirata, Y.; Burstein, Y.; Listowsky, I.
DELTA3,DELTA2-enoyl-CoA isomerase is the protein that copurifies with human glutathione S-transferase from S-hexylglutathione affinity matrices
Biochem. J.
304
849-852
1994
Homo sapiens
Manually annotated by BRENDA team
Kilponen, J.M.; Palosaari, P.M.; Hiltunen, J.K.
Occurence of a long-chain DELTA3,DELTA2-enoyl-CoA isomerase in rat liver
Biochem. J.
269
223-226
1990
Rattus norvegicus
Manually annotated by BRENDA team
Kilponen, J.M.; Hiltunen, J.K.
beta-Oxidation of unsaturated fatty acids in humans. Isoforms of DELTA3,DELTA2-enoyl-CoA isomerase
FEBS Lett.
322
299-303
1993
Homo sapiens
Manually annotated by BRENDA team
Engeland, K.; Kindl, H.
Purification and characterization of a plant peroxisomal DELTA2,DELTA3-enoyl-CoA isomerase acting on 3-cis-enoyl-CoA and 3-trans-enoyl-CoA
Eur. J. Biochem.
196
699-705
1991
Cucumis sativus
Manually annotated by BRENDA team
Zeelen, J.P.; Pauptit, R.A.; Wierenga, R.A.; Kunau, W.H.; Hiltunen, J.K.
Crystallization and preliminary X-ray diffraction studies of mitochondrial short-chain delta3,delta2-enoyl-CoA isomerase from rat liver
J. Mol. Biol.
224
273-275
1992
Rattus norvegicus
Manually annotated by BRENDA team
Palossari, P.M.; Vihinen, M.; Mntsl.P.I.; Alexson, S.E.H.; Pihlajaniemi, T.; Hiltunen, J.K.
Amino acid sequence similarities of the mitochondrial short chain DELTA3,DELTA2-enoyl-CoA isomerase and peroxisomal multifunctional DELTA3,DELTA2-enoyl-CoA isomerase, 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase enzyme in rat liver. The proposed occurence of isomerization and hydratation in the same catalytic domain of the multifunctional enzyme
J. Biol. Chem.
266
10750-10753
1991
Rattus norvegicus
Manually annotated by BRENDA team
Stoffel, W.; Duker, M.; Hofmann, K.
Molecular cloning and gene organization of the mouse mitochondrial 3,2-trans-enoyl-CoA isomerase
FEBS Lett.
333
119-122
1993
Mus musculus
Manually annotated by BRENDA team
Yokota, S.; Hirose, A.; Mizugaki, M.
Immunocytochemical localization of DELTA3,DELTA2-enoyl-CoA isomerase in rat liver. The effects of di-(2-ethylhexyl)phthalate, a peroxisome proliferator
Biol. Cell.
66
327-334
1989
Rattus norvegicus
Manually annotated by BRENDA team
Kilponen, J.M.; Palosaari, P.M.; Sormunen, R.T.; Vihinen, M.; Hiltunen, J.K.
Isoenzymes of DELTA3,DELTA2-enoyl-CoA isomerase in rat liver
Prog. Clin. Biol. Res.
375
33-40
1992
Rattus norvegicus
Manually annotated by BRENDA team
Muller-Newen, G.; Stoffel, W.
Site-directed mutagenesis of putative active-site amino acid residues of 3,2-trans-enoyl-CoA isomerase, conserved within the low-homology isomerase/hydratase enzyme family
Biochemistry
32
11405-11412
1993
Rattus norvegicus
Manually annotated by BRENDA team
Mursula, A.M.; van Aalten, D.M.; Modis, Y.; Hiltunen, J.K.; Wierenga, R.K.
Crystallization and X-ray diffraction analysis of peroxisomal DELTA3-DELTA2-enoyl-CoA isomerase from Saccharomyces cerevisiae
Acta Crystallogr. Sect. D
56
1020-1023
2000
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Gurvitz, A.; Wabnegger, L.; Yagi, A.I.; Binder, M.; Hartig, A.; Ruis, H.; Hamilton, B.; Dawes, I.W.; Hiltunen, J.K.; Rottensteiner, H.
Function of human mitochondrial 2,4-dienoyl-CoA reductase and rat monofunctional DELTA3-DELTA2-enoyl-CoA isomerase in beta-oxidation of unsaturated fatty acids
Biochem. J.
344
903-914
1999
Rattus norvegicus (P23965)
-
Manually annotated by BRENDA team
Mursula, A.M.; Hiltunen, J.K.; Wierenga, R.K.
Structural studies on DELTA3-DELTA2-enoyl-CoA isomerase: the variable mode of assembly of the trimeric disks of the crotonase superfamily
FEBS Lett.
557
81-87
2004
Saccharomyces cerevisiae (Q05871), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Geisbrecht, B.V.; Zhu, D.; Schulz, K.; Nau, K.; Morrell, J.C.; Geraghty, M.; Schulz, H.; Erdmann, R.; Gould, S.J.
Molecular characterization of Saccharomyces cerevisiae DELTA3, DELTA2-enoyl-CoA isomerase
J. Biol. Chem.
273
33184-33191
1998
Saccharomyces cerevisiae (Q05871), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Geisbrecht, B.V.; Zhang, D.; Schulz, H.; Gould, S.J.
Characterization of PECI, a novel monofunctional DELTA(3),DELTA(2)-enoyl-CoA isomerase of mammalian peroxisomes
J. Biol. Chem.
274
21797-21803
1999
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Zhang, D.; Yu, W.; Geisbrecht, B.V.; Gould, S.J.; Sprecher, H.; Schulz, H.
Functional characterization of DELTA3,DELTA2-enoyl-CoA isomerases from rat liver
J. Biol. Chem.
277
9127-9132
2002
Rattus norvegicus
Manually annotated by BRENDA team
Ren, Y.; Schulz, H.
Metabolic functions of the two pathways of oleate beta-oxidation double bond metabolism during the beta-oxidation of oleic acid in rat heart mitochondria
J. Biol. Chem.
278
111-116
2003
Rattus norvegicus
Manually annotated by BRENDA team
Mursula, A.M.; van Aalten, D.M.; Hiltunen, J.K.; Wierenga, R.K.
The crystal structure of DELTA3-DELTA2-enoyl-CoA isomerase
J. Mol. Biol.
309
845-853
2001
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Li, D.; Wong, C.K.; Yu, W.H.; Li, P.
Cloning, expression, and purification of the functional DELTA3-DELTA2-enoyl-CoA isomerase fusion protein
Protein Expr. Purif.
26
35-41
2002
Rattus norvegicus
Manually annotated by BRENDA team
Robert, J.; Marchesini, S.; Delessert, S.; Poirier, Y.
Analysis of the beta-oxidation of trans-unsaturated fatty acid in recombinant Saccharomyces cerevisiae expressing a peroxisomal PHA synthase reveals the involvement of a reductase-dependent pathway
BIOCHIM. BIOPHYS. ACTA
1734
169-177
2005
Saccharomyces cerevisiae, Saccharomyces cerevisiae BJ1991
Manually annotated by BRENDA team
Bogdawa, H.; Delessert, S.; Poirier, Y.
Analysis of the contribution of the beta-oxidation auxiliary enzymes in the degradation of the dietary conjugated linoleic acid 9-cis-11-trans-octadecadienoic acid in the peroxisomes of Saccharomyces cerevisiae
BIOCHIM. BIOPHYS. ACTA
1735
204-213
2005
Saccharomyces cerevisiae, Saccharomyces cerevisiae BJ1991
Manually annotated by BRENDA team
Ren, Y.; Aguirre, J.; Ntamack, A.G.; Chu, C.; Schulz, H.
An alternative pathway of oleate beta-oxidation in Escherichia coli involving the hydrolysis of a dead end intermediate by a thioesterase
J. Biol. Chem.
279
11042-11050
2004
Escherichia coli, Escherichia coli B / ATCC 11303
Manually annotated by BRENDA team
Partanen, S.T.; Novikov, D.K.; Popov, A.N.; Mursula, A.M.; Hiltunen, J.K.; Wierenga, R.K.
The 1.3 A crystal structure of human mitochondrial DELTA3-DELTA2-enoyl-CoA isomerase shows a novel mode of binding for the fatty acyl group
J. Mol. Biol.
342
1197-1208
2004
Homo sapiens (P42126), Homo sapiens
Manually annotated by BRENDA team
Hubbard, P.A.; Yu, W.; Schulz, H.; Kim, J.J.
Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial DELTA3, DELTA2-enoyl-CoA isomerase
Protein Sci.
14
1545-1555
2005
Rattus sp.
Manually annotated by BRENDA team
Yu, W.; Chu, X.; Deng, G.; Liu, X.; Chen, G.; Li, D.
Mutation of Lys242 allows DELTA3-DELTA2-enoyl-CoA isomerase to acquire enoyl-CoA hydratase activity
Biochim. Biophys. Acta
1760
1874-1883
2006
Rattus norvegicus, Rattus norvegicus (P23965)
Manually annotated by BRENDA team
Vydra, J.; Selicharova, I.; Smutna, K.; Sanda, M.; Matouskova, E.; Burskova, E.; Prchalova, M.; Velenska, Z.; Coufal, D.; Jiracek, J.
Two-dimensional electrophoretic comparison of metastatic and non-metastatic human breast tumors using in vitro cultured epithelial cells derived from the cancer tissues
BMC Cancer
8
107
2008
Homo sapiens, Homo sapiens (P42126)
Manually annotated by BRENDA team
Goepfert, S.; Vidoudez, C.; Tellgren-Roth, C.; Delessert, S.; Hiltunen, J.K.; Poirier, Y.
Peroxisomal DELTA(3),DELTA(2)-enoyl CoA isomerases and evolution of cytosolic paralogues in embryophytes
Plant J.
56
728-742
2008
Arabidopsis thaliana
Manually annotated by BRENDA team
Walewski, J.L.; Ge, F.; Gagner, M.; Inabnet, W.B.; Pomp, A.; Branch, A.D.; Berk, P.D.
Adipocyte accumulation of long-chain fatty acids in obesity is multifactorial, resulting from increased fatty acid uptake and decreased activity of genes involved in fat utilization
Obes. Surg.
20
93-107
2010
Homo sapiens (P42126), Homo sapiens
Manually annotated by BRENDA team
Rasmussen, A.L.; Diamond, D.L.; McDermott, J.E.; Gao, X.; Metz, T.O.; Matzke, M.M.; Carter, V.S.; Belisle, S.E.; Korth, M.J.; Waters, K.M.; Smith, R.D.; Katze, M.G.
Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis
J. Virol.
85
11646-11654
2011
Hepacivirus C, Homo sapiens (P42126)
Manually annotated by BRENDA team
Geisbrecht, B.; Schulz, K.; Nau, K.; Geraghty, M.; Schulz, H.; Erdmann, R.; Gould, S.
Preliminary characterization of Yor180Cp Identification of a novel peroxisomal protein of Saccharomyces cerevisiae involved in fatty acid metabolism
Biochem. Biophys. Res. Commun.
260
28-34
1999
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4733
Manually annotated by BRENDA team
Onwukwe, G.U.; Koski, M.K.; Pihko, P.; Schmitz, W.; Wierenga, R.K.
Structures of yeast peroxisomal DELTA3,DELTA2-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole
Acta Crystallogr. Sect. D
71
2178-2191
2015
Saccharomyces cerevisiae (Q05871)
Manually annotated by BRENDA team
Justus, J.; Weigand, E.
The effect of a moderate zinc deficiency and dietary fat source on the activity and expression of the DELTA3DELTA2-enoyl-CoA isomerase in the liver of growing rats
Biol. Trace Elem. Res.
158
365-375
2014
Rattus norvegicus
Manually annotated by BRENDA team
Vydra, J.; Selicharova, I.; Smutna, K.; Sanda, M.; Matouskova, E.; Burskova, E.; Prchalova, M.; Velenska, Z.; Coufal, D.; Jiracek, J.
Two-dimensional electrophoretic comparison of metastatic and non-metastatic human breast tumors using in vitro cultured epithelial cells derived from the cancer tissues
BMC Cancer
8
107
2008
Homo sapiens (P42126), Homo sapiens
Manually annotated by BRENDA team
Van Weeghel, M.; Ofman, R.; Argmann, C.; Ruiter, J.; Claessen, N.; Oussoren, S.; Wanders, R.; Aten, J.; Houten, S.
Identification and characterization of Eci3, a murine kidney-specific DELTA3,DELTA2-enoyl-CoA isomerase
FASEB J.
28
1365-1374
2014
Rattus norvegicus, Mus musculus (Q78JN3)
Manually annotated by BRENDA team
Onwukwe, G.U.; Kursula, P.; Koski, M.K.; Schmitz, W.; Wierenga, R.K.
Human DELTA3,DELTA2-enoyl-CoA isomerase, type 2 a structural enzymology study on the catalytic role of its ACBP domain and helix-10
FEBS J.
282
746-768
2015
Homo sapiens (O75521)
Manually annotated by BRENDA team