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Acute Kidney Injury
D-dopachrome tautomerase predicts outcome but not the development of acute kidney injury after orthotopic liver transplantation.
Acute Lung Injury
Astilbin alleviates sepsis-induced acute lung injury by inhibiting the expression of macrophage inhibitory factor in rats.
Adenocarcinoma
D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth.
Adenocarcinoma
The MIF homologue D-dopachrome tautomerase promotes COX-2 expression through ?-catenin-dependent and -independent mechanisms.
Adenoma
Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation.
Adenomyosis
m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis.
Albinism
White mutants in mice shedding light on humans.
Albinism, Oculocutaneous
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration.
Albinism, Oculocutaneous
Dopachrome tautomerase variants in patients with oculocutaneous albinism.
Albinism, Oculocutaneous
Reduced glutathione disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization.
Angiomyolipoma
Protein Expression Analysis of Melanocyte Differentiation Antigen TRP-2.
Arthritis, Rheumatoid
Changes in macrophage inhibitory factor correlate with changes in bone mineral density in glucocorticoid-treated patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.
Arthritis, Rheumatoid
Salivary and serum concentrations of monocyte chemoattractant protein-1, macrophage inhibitory factor, and fractalkine in relation to rheumatoid arthritis and periodontitis.
Atherosclerosis
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.
Atherosclerosis
MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde.
Atherosclerosis
Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.
Atherosclerosis
[MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde (German version)].
Autoimmune Diseases
Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.
Autoimmune Diseases
MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde.
Autoimmune Diseases
[MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde (German version)].
Blister
UVB-induced inflammation gives increased d-dopachrome tautomerase activity in blister fluid which correlates with macrophage migration inhibitory factor.
Breast Neoplasms
Hypoxia-induced secretion of macrophage migration-inhibitory factor from MCF-7 breast cancer cells is regulated in a hypoxia-inducible factor-independent manner.
Breast Neoplasms
Regulation of macrophage inhibitory factor (MIF) by epidermal growth factor receptor (EGFR) in the MCF10AT model of breast cancer progression.
Carcinogenesis
Dysregulated D-dopachrome tautomerase, a hypoxia-inducible factor-dependent gene, cooperates with macrophage migration inhibitory factor in renal tumorigenesis.
Carcinogenesis
Overexpression of D-dopachrome tautomerase increases ultraviolet B irradiation-induced skin tumorigenesis in mice.
Carcinogenesis
The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors.
Carcinoma
Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells.
Carcinoma
Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase.
Carcinoma
Expression of macrophage migration-inhibitory factor is correlated with progression in oral cavity carcinomas.
Carcinoma
Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy.
Carcinoma, Non-Small-Cell Lung
Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase.
Carcinoma, Ovarian Epithelial
Serum levels of macrophage migration-inhibitory factor (MIF) have diagnostic, predictive and prognostic roles in epithelial ovarian cancer patients.
Central Nervous System Neoplasms
The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors.
Cholera
Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes.
Coccidioidomycosis
In vitro lymphocyte responses of coccidioidin skin test-positive and -negative persons to coccidioidin, spherulin, and a coccidioides cell wall antigen.
Colitis
Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production.
Colonic Neoplasms
GSK-3?-mediated fatty acid synthesis enhances epithelial to mesenchymal transition of TLR4-activated colorectal cancer cells through regulation of TAp63.
Colonic Neoplasms
Stromal cell-derived factor-1? and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells.
Coronary Artery Disease
When the Myocardium Gets MIFfed: Macrophage Inhibitory Factor as a Biomarker in Acute Coronary Artery Disease.
Cystic Fibrosis
Cystic Fibrosis Sputum DNA Has NETosis Characteristics and Neutrophil Extracellular Trap Release Is Regulated by Macrophage Migration-Inhibitory Factor.
Dementia
Polymorphisms of the macrophage inhibitory factor and C-reactive protein genes in subjects with Alzheimer's dementia.
Diabetes, Gestational
Macrophage migration-inhibitory factor is elevated in pregnant women with gestational diabetes mellitus.
Diabetic Nephropathies
Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy.
Diabetic Nephropathies
TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells.
Duodenal Ulcer
Expression of macrophage migration-inhibitory factor in duodenal ulcer and its relation to Helicobacter pylori infection.
Encephalomyelitis
Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis.
Endometriosis
Decreased levels of the potent regulator of monocyte/macrophage activation, interleukin-13, in the peritoneal fluid of patients with endometriosis.
Endotoxemia
Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF-2 in adipose tissue during endotoxemia.
Enterocolitis, Necrotizing
Up-regulation of macrophage inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
Esophageal Squamous Cell Carcinoma
Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy.
Eye Diseases
Studies of immunoreactivity to human lacrimal gland fractions in patients with ophthalmic Graves' disease.
Eye Diseases
Thyroid binding antibodies and other immunological abnormalities in patients with Graves' ophthalmopathy: effect of treatment with cyclophosphamide.
Fatty Liver
Liver proteomics in progressive alcoholic steatosis.
Glioblastoma
A DNA vaccine expressing tyrosinase-related protein-2 induces T-cell-mediated protection against mouse glioblastoma.
Glioblastoma
Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy.
Glioblastoma
Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma.
Glioblastoma
Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas.
Glioblastoma
Role of neurofibromin in modulation of expression of the tyrosinase-related protein 2 gene.
Glioblastoma
Variation in cytotoxic T-lymphocyte responses to peptides derived from tyrosinase-related protein-2.
Glioma
Cancer-testis and melanocyte-differentiation antigen expression in malignant glioma and meningioma.
Glioma
Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
Glioma
In vivo visualization of GL261-luc2 mouse glioma cells by use of Alexa Fluor-labeled TRP-2 antibodies.
Glioma
Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP downregulates stemness phenotype and mesenchymal trans-differentiation after irradiation in glioblastoma multiforme.
Glioma
Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma.
Glioma
Optimal epitope composition after antigen screening using a live bacterial delivery vector: Application to TRP-2.
Glomerulonephritis
MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde.
Glomerulonephritis
[MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde (German version)].
Graves Disease
Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2).
Heart Failure
Cardiomyocyte d-dopachrome tautomerase protects against heart failure.
Hepatitis C, Chronic
Association of macrophage inhibitory factor -1 polymorphisms with antiviral efficacy of type 1b chronic hepatitis C.
Hermanski-Pudlak Syndrome
Iron upregulates melanogenesis in cultured retinal pigment epithelial cells.
Hyperpigmentation
N-(3,5-dimethylphenyl)-3-methoxybenzamide (A(3)B(5)) targets TRP-2 and inhibits melanogenesis and melanoma growth.
Hyperpigmentation
Phenolic-rich Pomegranate Peel Extract: In Vitro, Cellular, and In Vivo Activities for Skin Hyperpigmentation Treatment.
Hypersensitivity
Cellular hypersensitivity: the production of antibody by cultures of lymphocytes producing macrophage inhibitory factor.
Hypersensitivity
Macrophage inhibitory factor (MIF): properties and role in delayed-type hypersensitivity.
Hypersensitivity, Delayed
[Delayed hypersensitivity in vitro. 4. Production of macrophage inhibitory factor by the cells of tuberculin sensitive animals cultivated in vitro with the antigen]
Hypopigmentation
Anti-tyrosinase-related protein-2 immune response in vitiligo patients and melanoma patients receiving active-specific immunotherapy.
Hypothyroidism
Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2).
Infections
Expression of macrophage migration-inhibitory factor in duodenal ulcer and its relation to Helicobacter pylori infection.
Infections
Mumps virus inhibits migration of primary human macrophages toward a chemokine gradient through a TNF-alpha dependent mechanism.
Infections
Phage-displayed peptide targeting on the Puumala hantavirus neutralization site.
Keratitis
Role of cytokines and chemokines in pseudomonal keratitis.
Leishmaniasis, Cutaneous
Candidate gene case-control and functional study shows macrophage inhibitory factor (MIF) polymorphism is associated with cutaneous leishmaniasis.
Leprosy
Production of macrophage inhibitory factor by patients with leprosy.
Leukemia
Serum and cerebrospinal fluid cytokines in children with acute encephalopathy.
Liver Diseases
[The expression of macrophage migration-inhibitory factor in HBV-infection-related liver diseases]
Lupus Erythematosus, Discoid
Macrophage Migration Inhibitory Factor (MIF) and Its Homologue d-Dopachrome Tautomerase (DDT) Inversely Correlate with Inflammation in Discoid Lupus Erythematosus.
Lupus Nephritis
Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.
Measles
Measles Vaccines Designed for Enhanced CD8+ T Cell Activation.
Melanoma
A bioinformatic approach to the identification of candidate genes for the development of new cancer diagnostics.
Melanoma
A novel form of melanoma apoptosis resistance: melanogenesis up-regulation in apoptotic B16-F0 cells delays ursolic acid-triggered cell death.
Melanoma
Activation of MITF by Argan Oil Leads to the Inhibition of the Tyrosinase and Dopachrome Tautomerase Expressions in B16 Murine Melanoma Cells.
Melanoma
Alpha-MSH and other melanogenic activators mediate opposite effects on tyrosinase and dopachrome tautomerase in B16/F10 mouse melanoma cells.
Melanoma
Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity.
Melanoma
Altered N-glycosylation in macrophage x melanoma fusion hybrids.
Melanoma
Altering Antigen Charge to Control Self-Assembly and Processing of Immune Signals During Cancer Vaccination.
Melanoma
An Aggressive Hypoxia Related Subpopulation of Melanoma Cells is TRP-2 Negative.
Melanoma
An autologous oral DNA vaccine protects against murine melanoma.
Melanoma
Anti-tyrosinase-related protein-2 immune response in vitiligo patients and melanoma patients receiving active-specific immunotherapy.
Melanoma
Antibacterial, Antioxidant and Melanogenesis Inhibitory Activity of Auraptene, a Coumarin from Ferula szowitsiana Root.
Melanoma
Characterization of anti-self CD8 T-cell responses stimulated by recombinant Listeria monocytogenes expressing the melanoma antigen TRP-2.
Melanoma
Combined vaccination and immunostimulatory antibodies provides durable cure of murine melanoma and induces transcriptional changes associated with positive outcome in human melanoma patients.
Melanoma
Comparative decreases in tyrosinase, TRP-1, TRP-2, and Pmel 17/silver antigenic proteins from melanotic to amelanotic stages of syngeneic mouse cutaneous melanomas and metastases.
Melanoma
Comparison of tyrosinase-related protein-2, S-100, and Melan A immunoreactivity in canine amelanotic melanomas.
Melanoma
Dendritic cells, loaded with recombinant bacteria expressing tumor antigens, induce a protective tumor-specific response.
Melanoma
Detection of circulating melanoma cells by RT-PCR amplification of three different melanocyte-specific mRNAs in a mouse model.
Melanoma
Detection of spontaneous CD4+ T-cell responses in melanoma patients against a tyrosinase-related protein-2-derived epitope identified in HLA-DRB1*0301 transgenic mice.
Melanoma
Development of a multiple-marker polymerase chain reaction assay for detection of metastatic melanoma in lymph node aspirates of dogs.
Melanoma
Down-regulation of tyrosinase, TRP-1, TRP-2 and MITF expressions by citrus press-cakes in murine B16 F10 melanoma.
Melanoma
Effect of amphotericin B on dopachrome tautomerase activity and other melanogenic parameters in cultured B16/F10 melanoma cells.
Melanoma
Effect of penicillin-streptomycin and other antibiotics on melanogenic parameters in cultured B16/F10 melanoma cells.
Melanoma
Elevated frequencies of self-reactive CD8+ T cells following immunization with a xenoantigen are due to the presence of a heteroclitic CD4+ T-cell helper epitope.
Melanoma
Establishment of a melanogenesis regulation assay system using a fluorescent protein reporter combined with the promoters for the melanogenesis-related genes in human melanoma cells.
Melanoma
Expression of tyrosinase, TRP-1 and TRP-2 in ultraviolet-irradiated human melanomas and melanocytes: TRP-2 protects melanoma cells from ultraviolet B induced apoptosis.
Melanoma
Expression of tyrosinase-related protein 2/DOPAchrome tautomerase in the retinoblastoma.
Melanoma
Expression studies of pigmentation and POU-domain genes in human melanoma cells.
Melanoma
Function of dopachrome oxidoreductase and metal ions in dopachrome conversion in the eumelanin pathway.
Melanoma
Functionality study of santalin as tyrosinase inhibitor: A potential depigmentation agent.
Melanoma
Genetic vaccination with "self" tyrosinase-related protein 2 causes melanoma eradication but not vitiligo.
Melanoma
Glycine hydroxamate inhibits tyrosinase activity and melanin contents through downregulating cAMP/PKA signaling pathways.
Melanoma
High-dose chemotherapy augments the efficacy of recombinant adenovirus vaccines and improves the therapeutic outcome.
Melanoma
HLA-independent heterogeneity of CD8+ T cell responses to MAGE-3, Melan-A/MART-1, gp100, tyrosinase, MC1R, and TRP-2 in vaccine-treated melanoma patients.
Melanoma
Human uveal melanoma cells produce macrophage migration-inhibitory factor to prevent lysis by NK cells.
Melanoma
Identification of multiple antigens recognized by tumor-infiltrating lymphocytes from a single patient: tumor escape by antigen loss and loss of MHC expression.
Melanoma
Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes.
Melanoma
Immunosensitization with a Bcl-2 small molecule inhibitor.
Melanoma
Immunostimulatory effects of CpG-ODN upon dendritic cell-based immunotherapy in a murine melanoma model.
Melanoma
In vitro and cellular activities of the selected fruits residues for skin aging treatment.
Melanoma
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
Melanoma
Incomplete expression of the tyrosinase gene family (tyrosinase, TRP-1, and TRP-2) in human malignant melanoma cells in vitro.
Melanoma
Induction of a systemic immune response by a polyvalent melanoma-associated antigen DNA vaccine for prevention and treatment of malignant melanoma.
Melanoma
Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice.
Melanoma
Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression.
Melanoma
Inhibitory effect of Gastrodia elata extract on melanogenesis in HM3KO melanoma cells.
Melanoma
Internal binding sites for MSH: analyses in wild-type and variant Cloudman melanoma cells.
Melanoma
Isoaspartyl post-translational modification triggers anti-tumor T and B lymphocyte immunity.
Melanoma
Langerhans-type dendritic cells electroporated with TRP-2 mRNA stimulate cellular immunity against melanoma: Results of a phase I vaccine trial.
Melanoma
Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells.
Melanoma
Levels of dopachrome tautomerase in human melanocytes cultured in vitro.
Melanoma
Melanization stimulating activity in the skin of the gilthead porgy, Sparus auratus.
Melanoma
Melanoma genomics reveals signatures of sensitivity to bio- and targeted therapies.
Melanoma
Melanoma patients respond to a new HLA-A*01-presented antigenic ligand derived from a multi-epitope region of melanoma antigen TRP-2.
Melanoma
Melanoma x macrophage fusion hybrids acquire increased melanogenesis and metastatic potential: altered N-glycosylation as an underlying mechanism.
Melanoma
Melatonin antagonizes alpha-melanocyte-stimulating hormone enhancement of melanogenesis in mouse melanoma cells by blocking the hormone-induced accumulation of the c locus tyrosinase.
Melanoma
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma.
Melanoma
Metastatic potential of human melanoma cells in nude mice--characterisation of phenotype, cytokine secretion and tumour-associated antigens.
Melanoma
Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas.
Melanoma
Morin Induces Melanogenesis via Activation of MAPK Signaling Pathways in B16F10 Mouse Melanoma Cells.
Melanoma
N-(3,5-dimethylphenyl)-3-methoxybenzamide (A(3)B(5)) targets TRP-2 and inhibits melanogenesis and melanoma growth.
Melanoma
Naturally processed and concealed HLA-A2.1-restricted epitopes from tumor-associated antigen tyrosinase-related protein-2.
Melanoma
Neutrophil mediated postoperative photoimmunotherapy against melanoma skin cancer.
Melanoma
Novel calreticulin-nanoparticle in combination with focused ultrasound induces immunogenic cell death in melanoma to enhance antitumor immunity.
Melanoma
Novel HLA-Cw8-restricted T cell epitopes derived from tyrosinase-related protein-2 and gp100 melanoma antigens.
Melanoma
Novel Quercetin Derivative of 3,7-Dioleylquercetin Shows Less Toxicity and Highly Potent Tyrosinase Inhibition Activity.
Melanoma
Phenolic-rich Pomegranate Peel Extract: In Vitro, Cellular, and In Vivo Activities for Skin Hyperpigmentation Treatment.
Melanoma
Phlorotannins with Potential Anti-tyrosinase and Antioxidant Activity Isolated from the Marine Seaweed Ecklonia stolonifera.
Melanoma
Pigment production in murine melanoma cells is regulated by tyrosinase, tyrosinase-related protein 1 (TRP1), DOPAchrome tautomerase (TRP2), and a melanogenic inhibitor.
Melanoma
Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus protein.
Melanoma
Pre-existing immunity to tyrosinase-related protein (TRP)-2, a new TRP-2 isoform, and the NY-ESO-1 melanoma antigen in a patient with a dramatic response to immunotherapy.
Melanoma
Preparation of purified tyrosinase devoid of dopachrome tautomerase from mammalian malignant melanocytes.
Melanoma
Processing of Tumor Antigen Differentially Impacts the Development of Helper and Effector CD4(+) T-cell Responses.
Melanoma
Protein Expression Analysis of Melanocyte Differentiation Antigen TRP-2.
Melanoma
Purification and N-glycosylation analysis of melanoma antigen dopachrome tautomerase.
Melanoma
Quantitative analysis of tyrosinase and tyrosinase-related protein-2 mRNA from melanoma cells in blood by real-time polymerase chain reaction.
Melanoma
Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase.
Melanoma
Regulation of mammalian melanogenesis. I: Partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase.
Melanoma
Role of microphthalmia transcription factor in regulation of melanocyte differentiation marker TRP-1.
Melanoma
RT in situ PCR detection of MART-1 and TRP-2 mRNA in formalin-fixed, paraffin-embedded tissues of melanoma and nevi.
Melanoma
RT-PCR detection of tyrosinase, gp100, MART1/Melan-A, and TRP-2 gene transcripts in peripheral blood of melanoma patients.
Melanoma
Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA.
Melanoma
Synthesis in vitro of 5,6-dihydroxyindole-2-carboxylic acid by dopachrome conversion factor from Cloudman S91 melanoma cells.
Melanoma
T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma.
Melanoma
Targeted co-delivery of Trp-2 polypeptide and monophosphoryl lipid A by pH-sensitive poly (?-amino ester) nano-vaccines for melanoma.
Melanoma
The amphibian melanization inhibiting factor (MIF) blocks the alpha-MSH effect on mouse malignant melanocytes.
Melanoma
The depigmenting effect of alpha-tocopheryl ferulate on human melanoma cells.
Melanoma
The expression of tyrosinase, tyrosinase-related proteins 1 and 2 (TRP1 and TRP2), the silver protein, and a melanogenic inhibitor in human melanoma cells of differing melanogenic activities.
Melanoma
The functional property of egg yolk phosvitin as a melanogenesis inhibitor.
Melanoma
The functional property of royal jelly 10-hydroxy-2-decenoic acid as a melanogenesis inhibitor.
Melanoma
The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells.
Melanoma
The inhibitory effect of DL-alpha-tocopheryl ferulate in lecithin on melanogenesis.
Melanoma
The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model.
Melanoma
Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2.
Melanoma
Therapeutic vaccine generated by electrofusion of dendritic cells and tumour cells.
Melanoma
Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax.
Melanoma
Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes.
Melanoma
Traditional herbal prescription LASAP-C inhibits melanin synthesis in B16F10 melanoma cells and zebrafish.
Melanoma
Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage.
Melanoma
TRP-2 expression protects HEK cells from dopamine- and hydroquinone-induced toxicity.
Melanoma
TRP-2 specifically decreases WM35 cell sensitivity to oxidative stress.
Melanoma
Tumor-Specific Regulatory T Cells from the Bone Marrow Orchestrate Antitumor Immunity in Breast Cancer.
Melanoma
Tyrosinase-related proteins suppress tyrosinase-mediated cell death of melanocytes and melanoma cells.
Melanoma
Upregulation of mRNA for the melanocortin-1 receptor but not for melanogenic proteins in macrophage x melanoma fusion hybrids exhibiting increased melanogenic and metastatic potential.
Melanoma
Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus.
Melanoma, Amelanotic
Comparison of tyrosinase-related protein-2, S-100, and Melan A immunoreactivity in canine amelanotic melanomas.
Melanoma, Amelanotic
Enhanced melanogenesis induced by tyrosinase gene-transfer increases boron-uptake and killing effect of boron neutron capture therapy for amelanotic melanoma.
Melanoma, Experimental
Acanthoic acid inhibits melanogenesis through tyrosinase downregulation and melanogenic gene expression in B16 melanoma cells.
Melanoma, Experimental
Antioxidative and melanogenesis-inhibitory activities of caffeoylquinic acids and other compounds from moxa.
Melanoma, Experimental
Augmented induction of CD8+ cytotoxic T-cell response and antitumour resistance by T helper type 1-inducing peptide.
Melanoma, Experimental
Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.
Melanoma, Experimental
Characterization of anti-self CD8 T-cell responses stimulated by recombinant Listeria monocytogenes expressing the melanoma antigen TRP-2.
Melanoma, Experimental
Genetic vaccination with "self" tyrosinase-related protein 2 causes melanoma eradication but not vitiligo.
Melanoma, Experimental
Glycosidic inhibitors of melanogenesis from leaves of Momordica charantia.
Melanoma, Experimental
Glycosidic inhibitors of melanogenesis from leaves of Passiflora edulis.
Melanoma, Experimental
Immunogene therapy for murine melanoma using recombinant adenoviral vectors expressing melanoma-associated antigens.
Melanoma, Experimental
Kaliziri extract upregulates tyrosinase, TRP-1, TRP-2 and MITF expression in murine B16 melanoma cells.
Melanoma, Experimental
Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells.
Melanoma, Experimental
Limonoids from Azadirachta indica var. siamensis Extracts and Their Cytotoxic and Melanogenesis-Inhibitory Activities.
Melanoma, Experimental
Mechanism of pigmentation by minocycline in murine B16 melanoma cells.
Melanoma, Experimental
Melanogenesis Inhibitory Activity of Sesquiterpenes from Canarium ovatum Resin in Mouse B16 Melanoma Cells.
Melanoma, Experimental
Melanogenesis-inhibitory activities of limonoids and tricyclic diterpenoids from Azadirachta indica.
Melanoma, Experimental
Melanogenesis-inhibitory activity of aromatic glycosides from the stem bark of Acer buergerianum.
Melanoma, Experimental
Melanogenesis-Inhibitory and Cytotoxic Activities of Limonoids, Alkaloids, and Phenolic Compounds from Phellodendron amurense Bark.
Melanoma, Experimental
Over-expression of MSG1 transcriptional co-activator increases melanin in B16 melanoma cells: a possible role for MSG1 in melanogenesis.
Melanoma, Experimental
Simultaneous targeting of tumor antigens and the tumor vasculature using T lymphocyte transfer synergize to induce regression of established tumors in mice.
Melanoma, Experimental
Synthesis in vitro of 5,6-dihydroxyindole-2-carboxylic acid by dopachrome conversion factor from Cloudman S91 melanoma cells.
Melanoma, Experimental
The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells.
Melanoma, Experimental
Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2.
Melanoma, Experimental
Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma.
Melanoma, Experimental
Two new lignans and melanogenesis inhibitors from Schisandra nigra.
Melanosis
Histopathological study of the treatment of melasma lesions using a low-fluence Q-switched 1064-nm neodymium:yttrium-aluminium-garnet laser.
Meningioma
Cancer-testis and melanocyte-differentiation antigen expression in malignant glioma and meningioma.
Microphthalmos
Agouti signal protein regulation in human melanoma cells.
Microphthalmos
Coordinate extinction of melanocyte-specific gene expression in hybrid cells.
Microphthalmos
Melanoma genomics reveals signatures of sensitivity to bio- and targeted therapies.
Microphthalmos
Touchtone promotes survival of embryonic melanophores in zebrafish.
Microphthalmos
Tyrosine levels regulate the melanogenic response to alpha-melanocyte-stimulating hormone in human melanocytes: implications for pigmentation and proliferation.
Multiple Sclerosis
Genetic Variant rs755622 Regulates Expression of the Multiple Sclerosis Severity Modifier D-Dopachrome Tautomerase in a Sex-Specific Way.
Multiple Sclerosis
Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.
Multiple Sclerosis
MIF and D-DT are potential disease severity modifiers in male MS subjects.
Multiple Sclerosis
Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple Sclerosis.
Muscle Spasticity
Diethylcarbamazine activates TRP channels including TRP-2 in filaria, Brugia malayi.
Myocardial Infarction
Is insulin an antiinflammatory molecule?
Myocardial Ischemia
Compartmentalized Protective and Detrimental Effects of Endogenous Macrophage Migration-Inhibitory Factor Mediated by CXCR2 in a Mouse Model of Myocardial Ischemia/Reperfusion.
Neoplasm Metastasis
An Aggressive Hypoxia Related Subpopulation of Melanoma Cells is TRP-2 Negative.
Neoplasm Metastasis
Comparative decreases in tyrosinase, TRP-1, TRP-2, and Pmel 17/silver antigenic proteins from melanotic to amelanotic stages of syngeneic mouse cutaneous melanomas and metastases.
Neoplasm Metastasis
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
Neoplasm, Residual
Xenogeneic DNA immunization in melanoma models for minimal residual disease.
Neoplasms
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration.
Neoplasms
A Novel Brain Injury Biomarker Correlates with Cyanosis in Infants with Congenital Heart Disease.
Neoplasms
A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation.
Neoplasms
Acute alcohol intake impairs lung inflammation by changing pro- and anti-inflammatory mediator balance.
Neoplasms
Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor.
Neoplasms
Adipose tissue-derived adiponectin expression is significantly associated with increased post operative mortality in horses undergoing emergency abdominal surgery.
Neoplasms
Altering Antigen Charge to Control Self-Assembly and Processing of Immune Signals During Cancer Vaccination.
Neoplasms
Alternative roles for interferon-gamma in the immune response to DNA vaccines encoding related melanosomal antigens.
Neoplasms
An Aggressive Hypoxia Related Subpopulation of Melanoma Cells is TRP-2 Negative.
Neoplasms
Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study.
Neoplasms
Cell cycle dysregulation in pituitary oncogenesis.
Neoplasms
Comparative decreases in tyrosinase, TRP-1, TRP-2, and Pmel 17/silver antigenic proteins from melanotic to amelanotic stages of syngeneic mouse cutaneous melanomas and metastases.
Neoplasms
Comparison of tyrosinase-related protein-2, S-100, and Melan A immunoreactivity in canine amelanotic melanomas.
Neoplasms
Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes.
Neoplasms
Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
Neoplasms
D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth.
Neoplasms
Detection of a polyoma virus-induced tumor-associated membrane antigen in mouse cells by the macrophage migration inhibition test.
Neoplasms
Development of a multiple-marker polymerase chain reaction assay for detection of metastatic melanoma in lymph node aspirates of dogs.
Neoplasms
Differences in the hepatic signal transcription pathway and cytokine expression between thermal injury and sepsis.
Neoplasms
Efficacy and Therapeutic Potential of Curcumin Against Sepsis-Induced Chronic Lung Injury in Male Albino Rats.
Neoplasms
Enhancing Immune Responses to Cancer Vaccines Using Multi-Site Injections.
Neoplasms
Estradiol selectively regulates innate immune function by polarized human uterine epithelial cells in culture.
Neoplasms
Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy.
Neoplasms
Fat cell-derived modulators of vascular cell pathophysiology: the list keeps growing.
Neoplasms
Genetic vaccination with "self" tyrosinase-related protein 2 causes melanoma eradication but not vitiligo.
Neoplasms
Human uveal melanoma cells produce macrophage migration-inhibitory factor to prevent lysis by NK cells.
Neoplasms
Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes.
Neoplasms
Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma.
Neoplasms
Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model.
Neoplasms
Immunogene therapy for murine melanoma using recombinant adenoviral vectors expressing melanoma-associated antigens.
Neoplasms
Immunohistochemical diagnosis of canine oral amelanotic melanocytic neoplasms.
Neoplasms
Immunostimulatory effects of CpG-ODN upon dendritic cell-based immunotherapy in a murine melanoma model.
Neoplasms
Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model.
Neoplasms
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
Neoplasms
Inflammatory cytokine expression on the ocular surface in the Botulium toxin B induced murine dry eye model.
Neoplasms
Is insulin an antiinflammatory molecule?
Neoplasms
Knockdown of D-dopachrome Tautomerase Inhibits Cell Proliferation in Human HepG2 Cell Line.
Neoplasms
L-lysine ameliorates sepsis-induced acute lung injury in a lipopolysaccharide-induced mouse model.
Neoplasms
L-Lysine protects against sepsis-induced chronic lung injury in male albino rats.
Neoplasms
Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy.
Neoplasms
Macrophage migration inhibitory factor and hypothalamo-pituitary-adrenal function during critical illness.
Neoplasms
Macrophage migration-inhibitory factor levels in serum of patients with ovarian cancer correlates with poor prognosis.
Neoplasms
Matrix metalloproteinases-7, -8, -9 and TIMP-1 in the follow-up of diisocyanate-induced asthma.
Neoplasms
Mechanistic Evaluation of the Protective Effect of Carnosine on Acute Lung Injury in Sepsis Rats.
Neoplasms
Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.
Neoplasms
Melanoma patients respond to a new HLA-A*01-presented antigenic ligand derived from a multi-epitope region of melanoma antigen TRP-2.
Neoplasms
Melanoma progression despite infiltration by in vivo-primed TRP-2-specific T cells.
Neoplasms
Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma.
Neoplasms
Novel HLA-Cw8-restricted T cell epitopes derived from tyrosinase-related protein-2 and gp100 melanoma antigens.
Neoplasms
Optimal epitope composition after antigen screening using a live bacterial delivery vector: Application to TRP-2.
Neoplasms
Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer.
Neoplasms
Pre-existing immunity to tyrosinase-related protein (TRP)-2, a new TRP-2 isoform, and the NY-ESO-1 melanoma antigen in a patient with a dramatic response to immunotherapy.
Neoplasms
Processing of Tumor Antigen Differentially Impacts the Development of Helper and Effector CD4(+) T-cell Responses.
Neoplasms
Production of a serine-protease with macrophage migration-inhibitory factor activity by virus-transformed cells and human tumor cell lines.
Neoplasms
Proliferation of NS0 cells in protein-free medium: the role of cell-derived proteins, known growth factors and cellular receptors.
Neoplasms
Provision of granulocyte-macrophage colony-stimulating factor converts an autoimmune response to a self-antigen into an antitumor response.
Neoplasms
Recognition of an antigenic peptide derived from tyrosinase-related protein-2 by CTL in the context of HLA-A31 and -A33.
Neoplasms
Role of cytokines and chemokines in pseudomonal keratitis.
Neoplasms
SCIB2, an antibody DNA vaccine encoding NY-ESO-1 epitopes, induces potent antitumor immunity which is further enhanced by checkpoint blockade.
Neoplasms
Serum levels of macrophage migration-inhibitory factor (MIF) have diagnostic, predictive and prognostic roles in epithelial ovarian cancer patients.
Neoplasms
Simultaneous targeting of tumor antigens and the tumor vasculature using T lymphocyte transfer synergize to induce regression of established tumors in mice.
Neoplasms
Stromal-dependent tumor promotion by MIF family members.
Neoplasms
Suppression of T-cell mediated lymphokine production but not cytotoxic activity by macrophages.
Neoplasms
T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma.
Neoplasms
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy.
Neoplasms
The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors.
Neoplasms
The Role of Mast Cells in Aspirin-Exacerbated Respiratory Disease (AERD) Pathogenesis: Implications for Future Therapeutics.
Neoplasms
Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2.
Neoplasms
Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax.
Neoplasms
Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes.
Neoplasms
Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model.
Neoplasms
Tumor microenvironment MIF directs the accumulation of IL-17-producing tumor-infiltrating lymphocytes and predicts favorable survival in nasopharyngeal carcinoma patients.
Neoplasms
Tumor-Specific Regulatory T Cells from the Bone Marrow Orchestrate Antitumor Immunity in Breast Cancer.
Neoplasms
Tyrosinase-related proteins suppress tyrosinase-mediated cell death of melanocytes and melanoma cells.
Neoplasms
Value of dopachrome tautomerase detection in the assessment of melanocytic tumors.
Neoplasms
Xenogeneic DNA immunization in melanoma models for minimal residual disease.
Neoplasms
[Immune-testicular regulation and cytokines]
Neuroblastoma
Basic Gene Expression Characteristics of Glioma Stem Cells and Human Glioblastoma.
Neuroblastoma
Overexpression of Macrophage Migration Inhibitory Factor and Its Homologue D-Dopachrome Tautomerase as Negative Prognostic Factor in Neuroblastoma.
Nevus
Protein Expression Analysis of Melanocyte Differentiation Antigen TRP-2.
Nevus
RT in situ PCR detection of MART-1 and TRP-2 mRNA in formalin-fixed, paraffin-embedded tissues of melanoma and nevi.
Ovarian Neoplasms
Macrophage migration-inhibitory factor levels in serum of patients with ovarian cancer correlates with poor prognosis.
Ovarian Neoplasms
The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells.
Papillomavirus Infections
The Role of DCT in HPV16 Infection of HaCaTs.
Periodontitis
Salivary and serum concentrations of monocyte chemoattractant protein-1, macrophage inhibitory factor, and fractalkine in relation to rheumatoid arthritis and periodontitis.
Prostatic Neoplasms
Association of macrophage inhibitory factor -173 gene polymorphism with biological behavior of prostate cancer.
Pseudomonas Infections
Suppression of the delayed-type hypersensitivity and cell-mediated immune responses to Listeria monocytogenes induced by Pseudomonas aeruginosa.
Retinal Diseases
Transcriptome analysis and molecular signature of human retinal pigment epithelium.
Retinoblastoma
Comparative linkage mapping of human chromosome 13 and bovine chromosome 12.
Retinoblastoma
Expression of tyrosinase-related protein 2/DOPAchrome tautomerase in the retinoblastoma.
Scleroderma, Systemic
Analysis of serum macrophage migration inhibitory factor and D-dopachrome tautomerase in systemic sclerosis.
Sepsis
Differences in the hepatic signal transcription pathway and cytokine expression between thermal injury and sepsis.
Sepsis
Is insulin an antiinflammatory molecule?
Sepsis
MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde.
Sepsis
The immunoneuroendocrine axis in critical illness: beneficial adaptation or neuroendocrine exhaustion?
Sepsis
[MIF in kidney diseases : A story of Dr. Jekyll and Mr. Hyde (German version)].
Shock, Septic
Is insulin an antiinflammatory molecule?
Shock, Septic
Macrophage migration inhibitory factor and hypothalamo-pituitary-adrenal function during critical illness.
Spinal Cord Injuries
D-dopachrome tautomerase activates COX2/PGE2 pathway of astrocytes to mediate inflammation following spinal cord injury.
Spinal Cord Injuries
Up-regulation of macrophage migration-inhibitory factor expression after compression-induced spinal cord injury in rats.
Stomach Neoplasms
Macrophage migration inhibitory factor and DJ-1 in gastric cancer: differences between high-incidence and low-incidence areas.
Stomach Neoplasms
Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer.
Urinary Bladder Neoplasms
Enhanced Mortality to Metastatic Bladder Cancer Cell Line MB49 in Vasoactive Intestinal Peptide Gene Knockout Mice.
Urogenital Neoplasms
MIF family proteins in genitourinary cancer: tumorigenic roles and therapeutic potential.
Urticaria
Immunohistochemical demonstration of migration inhibitory factor in different types of urticaria.
Uterine Cervical Neoplasms
Combined Knockdown of D-dopachrome Tautomerase and Migration Inhibitory Factor Inhibits the Proliferation, Migration, and Invasion in Human Cervical Cancer.
Vaccinia
Genetic vaccination with "self" tyrosinase-related protein 2 causes melanoma eradication but not vitiligo.
Vaccinia
Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.
Vascular Diseases
Fat cell-derived modulators of vascular cell pathophysiology: the list keeps growing.
Vascular System Injuries
Fat cell-derived modulators of vascular cell pathophysiology: the list keeps growing.
Vitiligo
A Newly Authenticated Compound from Traditional Chinese Medicine Decoction Induces Melanogenesis in B16-F10 Cells by Increasing Tyrosinase Activity.
Vitiligo
Absence of tyrosinase-related protein-2/dopachrome tautomerase transcripts in PBMCs from vitiligo patients.
Vitiligo
Anti-tyrosinase-related protein-2 immune response in vitiligo patients and melanoma patients receiving active-specific immunotherapy.
Vitiligo
Identification of pathogenic genes and transcription factors in vitiligo.
Vitiligo
Identification of TYR, TYRP1, DCT and LARP7 as related biomarkers and immune infiltration characteristics of vitiligo via comprehensive strategies.
Vitiligo
Immune-modulatory effects of lenalidomide inhibited the progression of lesions in a vitiligo mouse model.
Vitiligo
Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2).
Vitiligo
Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients.
Vitiligo
Macrophage inhibitory factor (MIF) gene polymorphisms are associated with disease susceptibility and with circulating MIF levels in active non-segmental vitiligo in patients from western Mexico.
Vitiligo
Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin.
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Udono, T.; Takahashi, K.; Yasumoto, K.; Yoshizawa, M.; Takeda, K.; Abe, T.; Tamai, M.; Shibahara, S.
Expression of tyrosinase-related protein 2/DOPAchrome tautomerase in the retinoblastoma
Exp. Eye Res.
72
225-234
2001
Homo sapiens
brenda
Pisarra, P.; Lupetti, R.; Palumbo, A.; Napolitano, A.; Prota, G.; Parmiani, G.; Anichini, A.; Sensi, M.
Human melanocytes and melanomas express novel mRNA isoforms of the tyrosinase-related protein-2/DOPAchrome tautomerase gene: molecular and functional characterization
J. Invest. Dermatol.
115
48-56
2000
Homo sapiens
brenda
Suzuki, H.; Takahashi, K.; Yasumoto, K.I.; Amae, S.; Yoshizawa, M.; Fuse, N.; Shibahara, S.
Role of neurofibromin in modulation of expression of the tyrosinase-related protein 2 gene
J. Biochem.
124
992-998
1998
Homo sapiens
brenda
Pennock, J.L.; Behnke, J.M.; Bickle, Q.D.; Devaney, E.; Grencis, R.K.; Isaac, R.E.; Joshua, G.W.; Selkirk, M.E.; Zhang, Y.; Meyer, D.J.
Rapid purification and characterization of L-dopachrome-methyl ester tautomerase (macrophage-migration-inhibitory factor) from Trichinella spiralis, Trichuris muris and Brugia pahangi
Biochem. J.
335
495-498
1998
Brugia pahangi, Homo sapiens, no activity in Caenorhabditis elegans, no activity in Heligmosomoides polygyrus, no activity in Hymenolepis diminuta, no activity in Nippostrongylus brasiliensis, no activity in Schistosoma haematobium, no activity in Schistosoma japonicum, no activity in Schistosoma mansoni, Trichinella spiralis, Trichuris muris
brenda
Pak, B.J.; Lee, J.; Thai, B.L.; Fuchs, S.Y.; Shaked, Y.; Ronai, Z.; Kerbel, R.S.; Ben-David, Y.
Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase
Oncogene
23
30-38
2004
Homo sapiens
brenda
Michard, Q.; Commo, S.; Belaidi, J.P.; Alleaume, A.M.; Michelet, J.F.; Daronnat, E.; Eilstein, J.; Duche, D.; Marrot, L.; Bernard, B.A.
TRP-2 specifically decreases WM35 cell sensitivity to oxidative stress
Free Radic. Biol. Med.
44
1023-1031
2008
Homo sapiens
brenda
Cross, J.V.; Rady, J.M.; Foss, F.W.; Lyons, C.E.; Macdonald, T.L.; Templeton, D.J.
Nutrient isothiocyanates covalently modify and inhibit the inflammatory cytokine macrophage migration inhibitory factor (MIF)
Biochem. J.
423
315-321
2009
Homo sapiens
brenda
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Roger, T.; Le Roy, D.; Karpinar, D.P.; Leng, L.; Bucala, R.; Zweckstetter, M.; Calandra, T.; Lashuel, H.A.
A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor
Biochemistry
48
9858-9870
2009
Homo sapiens
brenda
Garai, J.; Lorand, T.
Macrophage migration inhibitory factor (MIF) tautomerase inhibitors as potential novel anti-inflammatory agents: current developments
Curr. Med. Chem.
16
1091-1114
2009
Homo sapiens
brenda
Vavricka, C.J.; Ray, K.W.; Christensen, B.M.; Li, J.
Purification and N-glycosylation analysis of melanoma antigen dopachrome tautomerase
Protein J.
29
204-212
2010
Homo sapiens
brenda
Bam, M.; Bagchi, T.
Absence of tyrosinase-related protein-2/dopachrome tautomerase transcripts in PBMCs from vitiligo patients
Scand. J. Immunol.
69
366-373
2009
Homo sapiens
brenda
Merk, M.; Mitchell, R.A.; Endres, S.; Bucala, R.
D-dopachrome tautomerase (D-DT or MIF-2): doubling the MIF cytokine family
Cytokine
59
10-17
2012
Homo sapiens (P14174), Homo sapiens
brenda
Ishimoto, K.; Iwata, T.; Taniguchi, H.; Mizusawa, N.; Tanaka, E.; Yoshimoto, K.
D-dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytes
Cytokine
60
772-777
2012
Homo sapiens
brenda
Pasupuleti, V.; Du, W.; Gupta, Y.; Yeh, I.J.; Montano, M.; Magi-Galuzzi, C.; Welford, S.M.
Dysregulated D-dopachrome tautomerase, a hypoxia-inducible factor-dependent gene, cooperates with macrophage migration inhibitory factor in renal tumorigenesis
J. Biol. Chem.
289
3713-3723
2014
Homo sapiens
brenda
Iwata, T.; Taniguchi, H.; Kuwajima, M.; Taniguchi, T.; Okuda, Y.; Sukeno, A.; Ishimoto, K.; Mizusawa, N.; Yoshimoto, K.
The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism
PLoS ONE
7
e33402
2012
Homo sapiens
brenda
Merk, M.; Zierow, S.; Leng, L.; Das, R.; Du, X.; Schulte, W.; Fan, J.; Lue, H.; Chen, Y.; Xiong, H.; Chagnon, F.; Bernhagen, J.; Lolis, E.; Mor, G.; Lesur, O.; Bucala, R.
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)
Proc. Natl. Acad. Sci. USA
108
E577-E585
2011
Homo sapiens
brenda
Roger, T.; Schlapbach, L.J.; Schneider, A.; Weier, M.; Wellmann, S.; Marquis, P.; Vermijlen, D.; Sweep, F.C.; Leng, L.; Bucala, R.; Calandra, T.; Giannoni, E.
Plasma levels of macrophage migration inhibitory factor and D-dopachrome tautomerase show a highly specific profile in early life
Front. Immunol.
8
26
2017
Homo sapiens
brenda
Guo, D.; Guo, J.; Yao, J.; Jiang, K.; Hu, J.; Wang, B.; Liu, H.; Lin, L.; Sun, W.; Jiang, X.
D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth
Int. J. Cancer
139
2056-2067
2016
Homo sapiens
brenda
Kim, B.S.; Tilstam, P.V.; Hwang, S.S.; Simons, D.; Schulte, W.; Leng, L.; Sauler, M.; Ganse, B.; Averdunk, L.; Kopp, R.; Stoppe, C.; Bernhagen, J.; Pallua, N.; Bucala, R.
D-dopachrome tautomerase in adipose tissue inflammation and wound repair
J. Cell. Mol. Med.
21
35-45
2017
Homo sapiens
brenda
5.3.3.12 L-dopachrome isomerase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
