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Information on EC 5.3.1.8 - mannose-6-phosphate isomerase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9M884

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IUBMB Comments
A zinc protein.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9M884
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
phosphomannose isomerase, mannose phosphate isomerase, mannose-6-phosphate isomerase, phosphohexoisomerase, phosphomannoisomerase, phosphomannose-isomerase, phosphohexomutase, gtmpi, type i phosphomannose isomerase, type i pmi, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Phosphomannose isomerase
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D-mannose-6-phosphate ketol-isomerase
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-
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Isomerase, mannose phosphate
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Mannose phosphate isomerase
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-
-
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Phosphohexoisomerase
-
-
-
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Phosphohexomutase
-
-
-
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Phosphomannoisomerase
-
-
-
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Phosphomannose isomerase
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-
-
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Phosphphexomutase
-
-
-
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PMI
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
isomerization
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-
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intramolecular oxidoreduction
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-
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SYSTEMATIC NAME
IUBMB Comments
D-mannose-6-phosphate aldose-ketose-isomerase
A zinc protein.
CAS REGISTRY NUMBER
COMMENTARY hide
9023-88-5
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-Mannose 6-phosphate
D-Fructose 6-phosphate
show the reaction diagram
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-
-
-
r
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cd2+
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1 mM, no residual activity
dithiothreitol
L-ascorbic acid
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1 mM, 77% residual activity
p-chloromercuribenzoate
Zn2+
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1 mM, no residual activity
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0413 - 0.372
D-mannose 6-phosphate
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
syncytia induced by nematode Heterodera schachtii
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
induction of expression under continuous light. Diurnal expression pattern in parallel with the total Pmi1 activity and the total ascorbic acid content in leaf
Manually annotated by BRENDA team
additional information
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
MPI1_ARATH
432
0
48566
Swiss-Prot
other Location (Reliability: 2)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Agrobacterium tumefaciens
expression in Escherichia coli
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Maruta, T.; Yonemitsu, M.; Yabuta, Y.; Tamoi, M.; Ishikawa, T.; Shigeoka, S.
Arabidopsis phosphomannose isomerase 1, but not phosphomannose isomerase 2, is essential for ascorbic acid biosynthesis
J. Biol. Chem.
283
28842-28851
2008
Arabidopsis thaliana
Manually annotated by BRENDA team
Siddique, S.; Endres, S.; Atkins, J.M.; Szakasits, D.; Wieczorek, K.; Hofmann, J.; Blaukopf, C.; Urwin, P.E.; Tenhaken, R.; Grundler, F.M.; Kreil, D.P.; Bohlmann, H.
Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
184
457-472
2009
Arabidopsis thaliana (Q9M884)
Manually annotated by BRENDA team