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Information on EC 5.3.1.6 - ribose-5-phosphate isomerase and Organism(s) Coccidioides immitis and UniProt Accession P0CL19

for references in articles please use BRENDA:EC5.3.1.6
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EC Tree
IUBMB Comments
Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate.
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This record set is specific for:
Coccidioides immitis
UNIPROT: P0CL19
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Word Map
The taxonomic range for the selected organisms is: Coccidioides immitis
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
rpi, ribose-5-phosphate isomerase, phosphoriboisomerase, ribose phosphate isomerase, ctrpi, d-ribose-5-phosphate isomerase, ribosephosphate isomerase b, ribosephosphate isomerase a, ribose-5-phosphate isomerase b, ribose 5-phosphate isomerase a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ribose-5-phosphate isomerase B
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5-Phosphoribose isomerase
-
-
-
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D-Ribose 5-phosphate isomerase
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-
-
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D-ribose-5-phosphate ketol-isomerase
-
-
-
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D-xylose ketol-isomerase
-
-
-
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Isomerase, ribose phosphate
-
-
-
-
Phosphopentoisomerase
-
-
-
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Phosphopentose isomerase
-
-
-
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Phosphoriboisomerase
-
-
-
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Ribose phosphate isomerase
-
-
-
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Ribose-5-P isomerase
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-
-
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Ribosephosphate isomerase A
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-
-
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Ribosephosphate isomerase B
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-
-
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RPI
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
isomerization
-
-
-
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intramolecular oxidoreduction
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
D-ribose-5-phosphate aldose-ketose-isomerase
Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate.
CAS REGISTRY NUMBER
COMMENTARY hide
9023-83-0
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-ribose 5-phosphate
D-ribulose 5-phosphate
show the reaction diagram
-
-
-
r
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
D-ribose 5-phosphate
D-ribulose 5-phosphate
show the reaction diagram
-
-
-
r
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
iodoacetic acid
suicide inhibitor
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
co-crystallization in the presence of 20 mM ribose-5-phosphate or 20 mM ribose-5-phosphate with 12 mM MnCl2, sitting drop vapor diffusion method, using 0.1 M Na citrate pH 5.0, 20% (w/v) PEG 6000
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Ni-NTA column chromatography and Superdex 75 gel filtration
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21 (DE3) R3 Rosetta cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Edwards, T.E.; Abramov, A.B.; Smith, E.R.; Baydo, R.O.; Leonard, J.T.; Leibly, D.J.; Thompkins, K.B.; Clifton, M.C.; Gardberg, A.S.; Staker, B.L.; Van Voorhis, W.C.; Myler, P.J.; Stewart, L.J.
Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis
BMC Struct. Biol.
11
39
2011
Coccidioides immitis (P0CL19), Coccidioides immitis
Manually annotated by BRENDA team