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Information on EC 5.3.1.28 - D-sedoheptulose 7-phosphate isomerase and Organism(s) Campylobacter jejuni and UniProt Accession Q9PNE6

for references in articles please use BRENDA:EC5.3.1.28
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IUBMB Comments
In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core. In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.
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This record set is specific for:
Campylobacter jejuni
UNIPROT: Q9PNE6
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The taxonomic range for the selected organisms is: Campylobacter jejuni
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
phosphoheptose isomerase, hp0857, sedoheptulose-7-phosphate isomerase, sedoheptulose 7-phosphate isomerase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphoheptose isomerase
-
phosphoheptose isomerase
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PATHWAY SOURCE
PATHWAYS
-
-, -
SYSTEMATIC NAME
IUBMB Comments
D-glycero-D-manno-heptose 7-phosphate aldose-ketose-isomerase
In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core. In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-sedoheptulose 7-phosphate
D-glycero-D-manno-heptose 7-phosphate
show the reaction diagram
-
-
-
?
D-sedoheptulose 7-phosphate
D-glycero-D-manno-heptose 7-phosphate
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
D-sedoheptulose 7-phosphate
D-glycero-D-manno-heptose 7-phosphate
show the reaction diagram
-
-
-
?
D-sedoheptulose 7-phosphate
D-glycero-D-manno-heptose 7-phosphate
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Valvano, M.A.; Messner, P.; Kosma, P.
Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides
Microbiology
148
1979-1989
2002
Aneurinibacillus thermoaerophilus (Q9AGY7), Burkholderia mallei (Q9AI36), Burkholderia pseudomallei (Q93UJ2), Campylobacter jejuni (Q9PMN3), Campylobacter jejuni (Q9PNE6), Clostridium acetobutylicum (Q97EQ4), Escherichia coli (P63224), Haemophilus influenzae (P45093), Helicobacter pylori J99 (Q9ZKZ1), Mycobacterium tuberculosis (P9WGG1), Mycobacterium tuberculosis H37Rv (P9WGG1), Neisseria meningitidis (P0A0Y5), Neisseria meningitidis (P0A0Y6), Pseudomonas aeruginosa (Q9HVZ0), Salmonella enterica subsp. enterica serovar Typhimurium (P63223), Vibrio cholerae (Q9KPY2), Yersinia pestis (Q8ZBY7)
Manually annotated by BRENDA team