Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 5.3.1.1 - triose-phosphate isomerase

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma of Lung
Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors.
Triosephosphate isomerase and peroxiredoxin 6, two novel serum markers for human lung squamous cell carcinoma.
[Different proteome of human lung adenocarcinoma cells treated with NS-398 and cisplation.]
adenosine deaminase deficiency
Ultra-performance liquid chromatography-tandem mass spectrometry-based multiplex enzyme assay for six enzymes associated with hereditary hemolytic anemia.
adenylate kinase deficiency
Red cell enzymopathies as a model of inborn errors of metabolism.
Alzheimer Disease
Aging-related changes of triose phosphate isomerase in hippocampus of senescence accelerated mouse and the intervention of acupuncture.
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.
Chronic Cocaine Use Causes Changes in the Striatal Proteome Depending on the Endogenous Expression of Pleiotrophin.
Methylglyoxal Produced by Amyloid-? Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease.
The pathophysiology of triose phosphate isomerase dysfunction in Alzheimer's disease.
Anemia
Autoantibodies against triosephosphate isomerase. A possible clue to pathogenesis of hemolytic anemia in infectious mononucleosis.
Prolonged haemolytic anaemia in malaria and autoantibodies against triosephosphate isomerase.
Anemia, Hemolytic
Autoantibodies against triosephosphate isomerase. A possible clue to pathogenesis of hemolytic anemia in infectious mononucleosis.
Deficiencies of glycolytic enzymes as a possible cause of hemolytic anemia.
Hemolytic anemia and progressive neurologic impairment: think about triosephosphate isomerase deficiency.
Hereditary triosephosphate isomerase (TPI) deficiency: two severely affected brothers one with and one without neurological symptoms.
Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme.
Human triosephosphate isomerase deficiency resulting from mutation of Phe-240.
Identification of protein quality control regulators using a Drosophila model of TPI deficiency.
Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Myopathy with altered mitochondria due to a triosephosphate isomerase (TPI) deficiency.
Neurological findings in triosephosphate isomerase deficiency.
Prolonged haemolytic anaemia in malaria and autoantibodies against triosephosphate isomerase.
Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.
Triose phosphate isomerase deficiency associated with two novel mutations in TPI gene.
Triose phosphate isomerase deficiency: prenatal diagnosis.
Triose phosphate isomerase deficiency: report of a family.
Triosephosphate isomerase activity-deficient mice show haemolytic anaemia in homozygous condition.
Triosephosphate isomerase deficiency with hemolytic anemia and severe neuromuscular disease: familial and biochemical studies of a case found in Spain.
Triosephosphate isomerase deficiency. A case report with neuropathological findings.
Triosephosphate isomerase deficiency: 2 new cases.
Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease.
Triosephosphate isomerase deficiency: a patient with Val231Met mutation.
Triosephosphate isomerase deficiency: biochemical and molecular genetic analysis for prenatal diagnosis.
Triosephosphate isomerase deficiency: haemolytic anaemia, myopathy with altered mitochondria and mental retardation due to a new variant with accelerated enzyme catabolism and diminished specific activity.
Triosephosphate isomerase deficiency: predictions and facts.
[A case of congenital non-spherocytic hemolytic anemia caused by triose phosphate isomerase deficiency. Prenatal diagnosis]
Anemia, Hemolytic, Congenital
HEREDITARY HEMOLYTIC ANEMIA WITH TRIOSEPHOSPHATE ISOMERASE DEFICIENCY.
Triosephosphate isomerase deficiency in a child with congenital hemolytic anemia and severe hypotonia.
[Congenital hemolytic anemia due to triosephosphate isomerase deficiency]
Anemia, Hemolytic, Congenital Nonspherocytic
Triose phosphate isomerase deficiency: prenatal diagnosis.
Anemia, Macrocytic
Acute myeloblastic leukemia following non-Hodgkin lymphoma in an adolescent. A report of a case with preleukemic syndrome, and review of the literature.
Astrocytoma
Integrated proteomic platforms for the comparative characterization of medulloblastoma and pilocytic astrocytoma pediatric brain tumors: a preliminary study.
Bacterial Infections
Triosephosphate isomerase deficiency: a patient with Val231Met mutation.
Brain Neoplasms
Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection.
Breast Neoplasms
Detection of autoantibodies against cyclophilin A and triosephosphate isomerase in sera from breast cancer patients by proteomic analysis.
Bronchopneumonia
Glycolytic enzymes from human autoptic brain cortex: normal aged and demented cases.
Carcinogenesis
Triose-phosphate isomerase is a novel target of miR-22 and miR-28, with implications in tumorigenesis.
Carcinoma
Phenotypic analysis of ovarian carcinoma: polypeptide expression in benign, borderline and malignant tumors.
Triosephosphate isomerase and peroxiredoxin 6, two novel serum markers for human lung squamous cell carcinoma.
[Screening of differentially expressed proteins from human esophageal cancer and esophageal tissues by two-dimensional difference gel electrophoresis and mass spectrometry]
Carcinoma, Hepatocellular
Analyses of polypeptides in the liver of a novel mutant (LEC rats) to hereditary hepatitis and hepatoma by two-dimensional gel electrophoresis: identification of P29/6.8 as carbonic anhydrase III and triosephosphate isomerase.
Triosephosphate isomerase 1 suppresses growth, migration and invasion of hepatocellular carcinoma cells.
Carcinoma, Squamous Cell
Triosephosphate isomerase and peroxiredoxin 6, two novel serum markers for human lung squamous cell carcinoma.
[Screening of differentially expressed proteins from human esophageal cancer and esophageal tissues by two-dimensional difference gel electrophoresis and mass spectrometry]
Cardiomyopathies
Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
Cataract
Human lens enzyme alterations with age and cataract: glyceraldehyde-3-P dehydrogenase and triose phosphate isomerase.
Cerebellar Ataxia
Autoantibodies in postinfectious acute cerebellar ataxia.
Chagas Disease
1,2,4-thiadiazol-5(4H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition.
Highly specific inactivation of triosephosphate isomerase from Trypanosoma cruzi.
How an Inhibitor Bound to Subunit Interface Alters Triosephosphate Isomerase Dynamics.
New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: a deeper insight into the mechanism of inhibition.
On the Self-Assembly of a Highly Selective Benzothiazole-Based TIM Inhibitor in Aqueous Solution.
Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.
Selective inactivation of triosephosphate isomerase from Trypanosoma cruzi by brevifolin carboxylate derivatives isolated from Geranium bellum Rose.
Coinfection
Multilocus genotyping of Giardia duodenalis isolated from patients in Egypt.
Prevalence and mulilocus genotypes of Giardia duodenalis infecting pigs in Ogun state, Nigeria.
Colorectal Neoplasms
Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester.
Cri-du-Chat Syndrome
Studies on human triosephosphate isomerase. 3. Characterization of the enzyme from patients with the cri du chat syndrome.
Cysts
Distribution of Giardia duodenalis genotypes and subgenotypes in raw urban wastewater in Milwaukee, Wisconsin.
Disulfide bridges in the mesophilic triosephosphate isomerase from Giardia lamblia are related to oligomerization and activity.
Intestinal parasites and genotyping of Giardia duodenalis in children: first report of genotype B in isolates from human clinical samples in Mexico.
Multilocus sequence typing of canine Giardia duodenalis from South Eastern European countries.
Quantification of viable Giardia cysts and Cryptosporidium oocysts in wastewater using propidium monoazide quantitative real-time PCR.
Understanding Giardia infections among rural communities using the one health approach.
Dehydration
Dual activity of quinolinate synthase: triose phosphate isomerase and dehydration activities play together to form quinolinate.
Importance of inositols and their derivatives in cowpea under root dehydration: An omics perspective.
Water stress enhances beta-amylase activity in cucumber cotyledons.
Dementia
Glycolytic enzymes from human autoptic brain cortex: normal aged and demented cases.
Dyskinesias
Adverse effects of dopamine potentiation by long-term treatment with selegiline.
Hereditary triosephosphate isomerase (TPI) deficiency: two severely affected brothers one with and one without neurological symptoms.
Encephalomyelitis
Changes of B cell subsets in central pathological process of autoimmune encephalomyelitis in mice.
Encephalomyelitis, Autoimmune, Experimental
Changes of B cell subsets in central pathological process of autoimmune encephalomyelitis in mice.
Epstein-Barr Virus Infections
Affinity purification of antibodies from sera using polyvinylidenedifluoride (PVDF) membranes as coupling matrices for antigens presented by autoantibodies to triosephosphate isomerase.
Haemolysis in hepatitis A virus infections coinciding with the occurrence of autoantibodies against triosephosphate isomerase and the reactivation of latent persistent Epstein-Barr virus infection.
Erythema
Molecular characterization and allergenicity potential of triosephosphate isomerase from Sarcoptes scabiei.
Esophageal Achalasia
Triosephosphate isomerase, carbonic anhydrase, and creatinine kinase-brain isoform are possible antigen targets in patients with achalasia.
Esophageal Neoplasms
[Screening of differentially expressed proteins from human esophageal cancer and esophageal tissues by two-dimensional difference gel electrophoresis and mass spectrometry]
Food Hypersensitivity
Proteome mining for novel IgE-binding proteins from the German cockroach (Blattella germanica) and allergen profiling of patients.
fructose-bisphosphate aldolase deficiency
Red cell enzymopathies as a model of inborn errors of metabolism.
Genetic Diseases, Inborn
Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
Structural analysis on mutation residues and interfacial water molecules for human TIM disease understanding.
Giardiasis
First genetic characterisation of Giardia in human isolates from Jordan.
Molecular characterization of Giardia duodenalis isolates from police and farm dogs in China.
Molecular epidemiology of Giardia duodenalis infection in humans in Southern Ethiopia: a triosephosphate isomerase gene-targeted analysis.
Molecular epidemiology of giardiasis among Orang Asli in Malaysia: application of the triosephosphate isomerase gene.
Structural and functional perturbation of giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
Glioma
Quantitative proteomic analysis of global effect of LLL12 on U87 cell's proteome: An insight into the molecular mechanism of LLL12.
Heart Failure
Triose phosphate isomerase deficiency: prenatal diagnosis.
Triose phosphate isomerase deficiency: report of a family.
Hemochromatosis
Metabolic cardiomyopathies.
Hepatitis
Analyses of polypeptides in the liver of a novel mutant (LEC rats) to hereditary hepatitis and hepatoma by two-dimensional gel electrophoresis: identification of P29/6.8 as carbonic anhydrase III and triosephosphate isomerase.
Hepatitis A
Haemolysis in hepatitis A virus infections coinciding with the occurrence of autoantibodies against triosephosphate isomerase and the reactivation of latent persistent Epstein-Barr virus infection.
Hemolysis and autoantibodies to triosephosphate isomerase in a patient with acute hepatitis A virus infection.
Hepatitis, Chronic
Identification of hepatocellular-carcinoma-associated antigens and autoantibodies by serological proteome analysis combined with protein microarray.
Hypersensitivity
Identification of Major Allergens in Watermelon.
Hypoalphalipoproteinemias
Erythrocyte lipids in triose-phosphate isomerase deficiency.
Infections
cDNA cloning and functional expression of the Schistosoma mansoni protective antigen triose-phosphate isomerase.
Changes in the contents of metabolites and enzyme activities in rice plants responding to Rhizoctonia solani Kuhn infection: activation of glycolysis and connection to phenylpropanoid pathway.
Comparison of PCR methods for detection of Leishmania siamensis infection.
Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma.
Helicobacter pylori in a Korean Isolate Expressed Proteins Differentially in Human Gastric Epithelial Cells.
Hemolysis and autoantibodies to triosephosphate isomerase in a patient with acute hepatitis A virus infection.
Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila.
Mixed Giardia duodenalis assemblage A and E infections in calves.
Molecular characterisation of Giardiaduodenalis in captive non-human primates reveals mixed assemblage A and B infections and novel polymorphisms.
Molecular epidemiology of Giardia duodenalis infection in humans in Southern Ethiopia: a triosephosphate isomerase gene-targeted analysis.
Occurrence and multilocus genotyping of Giardia duodenalis from post-weaned dairy calves in Sichuan province, China.
Prevalence and genotypes of Giardia lamblia from stray dogs and cats in Guangdong, China.
Proteomic analysis of fungal host factors differentially expressed by Fusarium graminearum infected with Fusarium graminearum virus-DK21.
Schistosoma japonicum triose-phosphate isomerase plasmid DNA vaccine protects pigs against challenge infection.
Stool antigen immunodetection for diagnosis of Giardia duodenalis infection in human subjects with HIV and cancer.
The metabolism of host RNAs in cells infected by an adenovirus E4 mutant.
Therapeutic targets for the treatment of microsporidiosis in humans.
Triosephosphate isomerase (TPI) facilitates the replication of WSSV in Exopalaemon carinicauda.
Triosephosphate isomerase deficiency: biochemical and molecular genetic analysis for prenatal diagnosis.
Triosephosphate isomerase gene characterization and potential zoonotic transmission of Giardia duodenalis.
Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection.
[Protective effects of co-immunization with SjCTPI-Hsp70 and interleukin-12 DNA vaccines against Schistosoma japonicum challenge infection in water buffalo]
Infectious Mononucleosis
Autoantibodies against triosephosphate isomerase. A possible clue to pathogenesis of hemolytic anemia in infectious mononucleosis.
Haemolysis in hepatitis A virus infections coinciding with the occurrence of autoantibodies against triosephosphate isomerase and the reactivation of latent persistent Epstein-Barr virus infection.
Successful plasmapheresis in corticosteroid-resistant hemolysis in infectious mononucleosis: role of autoantibodies against triosephosphate isomerase.
[Infectious mononucleosis: hemolysis by autoantibodies against triosephosphate isomerase]
Infertility
Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene.
Intellectual Disability
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Myopathy with altered mitochondria due to a triosephosphate isomerase (TPI) deficiency.
Triosephosphate isomerase deficiency: haemolytic anaemia, myopathy with altered mitochondria and mental retardation due to a new variant with accelerated enzyme catabolism and diminished specific activity.
Iron Overload
Synergistic Interaction of Light Alcohol Administration in the Presence of Mild Iron Overload in a Mouse Model of Liver Injury: Involvement of Triosephosphate Isomerase Nitration and Inactivation.
l-lactate dehydrogenase deficiency
Implications of the mitochondrial interactome of mammalian thioredoxin 2 for normal cellular function and disease.
Leishmaniasis, Visceral
Leishmania donovani triose phosphate isomerase: a potential vaccine target against visceral leishmaniasis.
Leukemia, Erythroblastic, Acute
Regulation of triosephosphate isomerase (TPI) gene expression in TPI deficient lymphoblastoid cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Acute myeloblastic leukemia following non-Hodgkin lymphoma in an adolescent. A report of a case with preleukemic syndrome, and review of the literature.
Lung Diseases
Triosephosphate isomerase and peroxiredoxin 6, two novel serum markers for human lung squamous cell carcinoma.
Lung Neoplasms
Association between Growth Differentiation Factor-15 (GDF-15) Serum Levels, Anorexia and Low Muscle Mass among Cancer Patients.
Secretomic analysis of large cell lung cancer cell lines using two-dimensional gel electrophoresis coupled to mass spectrometry.
Lupus Vasculitis, Central Nervous System
Association of anti-triosephosphate isomerase antibodies with aseptic meningitis in patients with neuropsychiatric systemic lupus erythematosus.
Lymphoma
Proteomics of canine lymphoma identifies potential cancer-specific protein markers.
Malaria
Prolonged haemolytic anaemia in malaria and autoantibodies against triosephosphate isomerase.
Structure-based inhibitor screening: a family of sulfonated dye inhibitors for malaria parasite triosephosphate isomerase.
Triosephosphate isomerase gene promoter variation: -5G/A and -8G/A polymorphisms in clinical malaria groups in two African populations.
Medulloblastoma
Integrated proteomic platforms for the comparative characterization of medulloblastoma and pilocytic astrocytoma pediatric brain tumors: a preliminary study.
Melanoma
Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
Rapid mass spectrometric peptide sequencing and mass matching for characterization of human melanoma proteins isolated by two-dimensional PAGE.
Metabolic Diseases
In silico prediction of the effects of mutations in the human triose phosphate isomerase gene: Towards a predictive framework for TPI deficiency.
Microsporidiosis
Sparse Evidence for Giardia intestinalis, Cryptosporidium spp. and Microsporidia Infections in Humans, Domesticated Animals and Wild Nonhuman Primates Sharing a Farm-Forest Mosaic Landscape in Western Uganda.
Therapeutic targets for the treatment of microsporidiosis in humans.
Mitochondrial Diseases
Implications of the mitochondrial interactome of mammalian thioredoxin 2 for normal cellular function and disease.
Muscle Hypotonia
Triosephosphate isomerase deficiency in a child with congenital hemolytic anemia and severe hypotonia.
Muscular Diseases
Myopathy with altered mitochondria due to a triosephosphate isomerase (TPI) deficiency.
Triosephosphate isomerase deficiency: haemolytic anaemia, myopathy with altered mitochondria and mental retardation due to a new variant with accelerated enzyme catabolism and diminished specific activity.
Neoplasm Metastasis
Novel cationic antimicrobial peptide GW-H1 induced caspase-dependent apoptosis of hepatocellular carcinoma cell lines.
Protein pattern difference in the colon cancer cell lines examined by two-dimensional differential in-gel electrophoresis and mass spectrometry.
Triosephosphate isomerase and peroxiredoxin 6, two novel serum markers for human lung squamous cell carcinoma.
Neoplasms
Clinical significance and prognostic value of Triosephosphate isomerase expression in gastric cancer.
Completion pneumonectomy for lung metastases.
Differential protein expression in primary breast cancer and matched axillary node metastasis.
Effects of 5'-azacytidine and alendronate on a hepatocellular carcinoma cell line: a proteomics perspective.
Enzymes in cancer. III. Triosephosphate isomerase activity of human blood serum in normal individuals and in individuals with various pathological conditions.
Identification and applications of repetitive probes for gene mapping in the mouse.
Identification of diagnostic upper gastrointestinal cancer tissue type-specific urinary biomarkers.
Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model.
Immunoproteomics reveals that cancer of the tongue and the gingivobuccal complex exhibit differential autoantibody response.
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis.
Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
New strategies for targeting glucose metabolism-mediated acidosis for colorectal cancer therapy.
Nuclear translocation of ?-catenin during mesenchymal stem cells differentiation into hepatocytes is associated with a tumoral phenotype.
Off-target effects related to the phosphorothioate modification of nucleic acids.
Overexpression of triosephosphate isomerase inhibits proliferation of chicken embryonal fibroblast cells.
Polypeptide expression in prostate hyperplasia and prostate adenocarcinoma.
Protein expression profiling in the spectrum of renal cell carcinomas.
Protein profile of MCF-7 breast cancer cell line treated with lectin delivered by CaCO3NPs revealed changes in molecular chaperones, cytoskeleton, and membrane-associated proteins.
Proteomic analysis of differential protein expression by brain metastases of gynecological malignancies.
Proteomic profiling reveals that resveratrol inhibits HSP27 expression and sensitizes breast cancer cells to doxorubicin therapy.
Proteomics analysis of the proliferative effect of low-dose ouabain on human endothelial cells.
Proteomics detection of S100A6 in tumor tissue interstitial fluid and evaluation of its potential as a biomarker of cholangiocarcinoma.
Role of triosephosphate isomerase and downstream functional genes on gastric cancer.
Serological proteome analysis of dogs with breast cancer unveils common serum biomarkers with human counterparts.
Structure-based inhibitor screening: a family of sulfonated dye inhibitors for malaria parasite triosephosphate isomerase.
Therapeutic Targeting of Cancer Metabolism with Triosephosphate Isomerase.
Three-dimensional neuroblastoma cell culture: proteomic analysis between monolayer and multicellular tumor spheroids.
Triose-phosphate isomerase is a novel target of miR-22 and miR-28, with implications in tumorigenesis.
[Proteomic analysis on portal vein tumor thrombus-associated proteins for hepatocellular carcinoma]
Nervous System Diseases
Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease.
Neuroblastoma
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.
Neurodegenerative Diseases
Chronic Cocaine Use Causes Changes in the Striatal Proteome Depending on the Endogenous Expression of Pleiotrophin.
Phenotyping of tianma-stimulated differentiated rat neuronal b104 cells by quantitative proteomics.
Neurologic Manifestations
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.
Triosephosphate isomerase deficiency: predictions and facts.
Neuromuscular Diseases
Triosephosphate isomerase deficiency with hemolytic anemia and severe neuromuscular disease: familial and biochemical studies of a case found in Spain.
Obesity
Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle.
Osteoarthritis
Proteomic surveillance of autoimmunity in osteoarthritis: identification of triosephosphate isomerase as an autoantigen in patients with osteoarthritis.
Ovarian Neoplasms
Glycoproteomics of paclitaxel resistance in human epithelial ovarian cancer cell lines: towards the identification of putative biomarkers.
Proteomic analysis of differential protein expression by brain metastases of gynecological malignancies.
Paralysis
wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death.
Parasitic Diseases
Structural and functional perturbation of giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
Parkinson Disease
Chronic Cocaine Use Causes Changes in the Striatal Proteome Depending on the Endogenous Expression of Pleiotrophin.
Implications of the mitochondrial interactome of mammalian thioredoxin 2 for normal cellular function and disease.
Peripheral Nervous System Diseases
Chronic axonal neuropathy with triosephosphate isomerase deficiency.
phosphoglycerate kinase deficiency
Deficiencies of glycolytic enzymes as a possible cause of hemolytic anemia.
Red cell enzymopathies as a model of inborn errors of metabolism.
Progeria
Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts.
Prostatic Neoplasms
Characterization of a New Allelic Variant of Triosephosphate Isomerase from the LNCaP Human Prostate Cancer Cell Line: Enzyme Inhibition and Spectroscopic Studies.
Pseudorabies
Minimal sequence and factor requirements for the initiation of transcription from an atypical, TATATAA box-containing housekeeping promoter.
pyruvate kinase deficiency
Increased erythrocyte deformability in fetal erythropoiesis and in erythrocytes deficient in glucose-6-phosphate dehydrogenase and other glycolytic enzymes.
Sarcoma
A putative homoeolog of human chromosome 12 in the owl monkey.
Sheep gene mapping: additional DNA markers included (CASB, CASK, LALBA, IGF-1 and AMH).
Sarcoma, Ewing
Glycolysis- and immune-related novel prognostic biomarkers of Ewing's sarcoma: glucuronic acid epimerase and triosephosphate isomerase 1.
Schistosomiasis
Human immune responses to Schistosoma mansoni vaccine candidate antigens.
The functional and immunological significance of some schistosome surface molecules.
Seizures
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Starvation
Genetic diversity and population structure of food-borne Staphylococcus carnosus strains.
Stomach Neoplasms
Clinical significance and prognostic value of Triosephosphate isomerase expression in gastric cancer.
Global gene expression analysis of knockdown Triosephosphate isomerase (TPI) gene in human gastric cancer cell line MGC-803.
Identification of diagnostic upper gastrointestinal cancer tissue type-specific urinary biomarkers.
Identification of triosephosphate isomerase as an anti-drug resistance agent in human gastric cancer cells using functional proteomic analysis.
Role of triosephosphate isomerase and downstream functional genes on gastric cancer.
Thrombosis
[Proteomic analysis on portal vein tumor thrombus-associated proteins for hepatocellular carcinoma]
Tongue Neoplasms
Immunoproteomics reveals that cancer of the tongue and the gingivobuccal complex exhibit differential autoantibody response.
Tremor
Neurological findings in triosephosphate isomerase deficiency.
Trichomonas Infections
Developing a new drug against trichomoniasis, new inhibitory compounds of the protein triosephosphate isomerase.
Triosephosphate isomerase as a therapeutic target against trichomoniasis.
triose-phosphate isomerase deficiency
A High-Content Screening Assay for Small Molecules That Stabilize Mutant Triose Phosphate Isomerase (TPI) as Treatments for TPI Deficiency.
Child Neurology: Triosephosphate isomerase deficiency.
Chronic axonal neuropathy with triosephosphate isomerase deficiency.
Differential effects on enzyme stability and kinetic parameters of mutants related to human triosephosphate isomerase deficiency.
Drosophila model of human inherited triosephosphate isomerase deficiency glycolytic enzymopathy.
Electrophoretic abnormality in triosephosphate isomerase deficiency.
Elevated frequency of carriers for triosephosphate isomerase deficiency in newborn infants.
Erythrocyte lipids in triose-phosphate isomerase deficiency.
Evidence for founder effect of the Glu104Asp substitution and identification of new mutations in triosephosphate isomerase deficiency.
First trimester studies of a fetus at risk for triose phosphate isomerase deficiency.
Hemolytic anemia and progressive neurologic impairment: think about triosephosphate isomerase deficiency.
Hereditary deficiency of triosephosphate isomerase in four unrelated families.
HEREDITARY HEMOLYTIC ANEMIA WITH TRIOSEPHOSPHATE ISOMERASE DEFICIENCY.
Hereditary triose phosphate isomerase deficiency: seven new homozygous cases.
Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme.
Human triosephosphate isomerase cDNA and protein structure. Studies of triosephosphate isomerase deficiency in man.
Human triosephosphate isomerase deficiency resulting from mutation of Phe-240.
Implications of the mitochondrial interactome of mammalian thioredoxin 2 for normal cellular function and disease.
In vitro nonenzymatic glycation of guanosine 5'-triphosphate by dihydroxyacetone phosphate.
Increased erythrocyte deformability in fetal erythropoiesis and in erythrocytes deficient in glucose-6-phosphate dehydrogenase and other glycolytic enzymes.
Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
Medical and Veterinary Importance of the Moonlighting Functions of Triosephosphate Isomerase.
Metabolic cardiomyopathies.
Metabolic correction of triose phosphate isomerase deficiency in vitro by complementation.
Modification in a screening test for triosephosphate isomerase deficiency.
Neurological findings in triosephosphate isomerase deficiency.
New haplotype for the Glu104Asp mutation in triose-phosphate isomerase deficiency and prenatal diagnosis in a Spanish family.
Novel human pathological mutations. Gene symbol: TPI1. Disease: triosephosphate isomerase deficiency.
Platelet function defect in triosephosphate isomerase deficiency.
Possibility of prenatal diagnosis of hereditary triose phosphate isomerase deficiency.
Prenatal diagnosis of a red-cell enzymopathy: triose phosphate isomerase deficiency.
Prenatal diagnosis of triose phosphate isomerase deficiency.
Prenatal diagnosis of triosephosphate isomerase deficiency.
Prevalence of partial deficiency of red cell triosephosphate isomerase in Germany--a study of 3000 people.
Reappraisal of triosephosphate isomerase deficiency.
Search for the pathogenesis of the differing phenotype in two compound heterozygote Hungarian brothers with the same genotypic triosephosphate isomerase deficiency.
Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.
Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface.
The feasibility of replacement therapy for inherited disorder of glycolysis: triosephosphate isomerase deficiency (review).
The rapid detection of triose phosphate isomerase deficiency.
Towards enzyme-replacement treatment in triosephosphate isomerase deficiency.
Triose phosphate isomerase deficiency associated with two novel mutations in TPI gene.
Triose phosphate isomerase deficiency in 3 French families: two novel null alleles, a frameshift mutation (TPI Alfortville) and an alteration in the initiation codon (TPI Paris).
Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes.
Triose phosphate isomerase deficiency.
Triose phosphate isomerase deficiency: prenatal diagnosis.
Triose phosphate isomerase deficiency: report of a family.
Triosephosphate isomerase deficiency in a child with congenital hemolytic anemia and severe hypotonia.
Triosephosphate isomerase deficiency with elevated sweat chloride test: report of a case.
Triosephosphate isomerase deficiency with hemolytic anemia and severe neuromuscular disease: familial and biochemical studies of a case found in Spain.
Triosephosphate isomerase deficiency. A case report with neuropathological findings.
Triosephosphate isomerase deficiency: 2 new cases.
Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease.
Triosephosphate isomerase deficiency: a patient with Val231Met mutation.
Triosephosphate isomerase deficiency: biochemical and molecular genetic analysis for prenatal diagnosis.
Triosephosphate isomerase deficiency: consequences of an inherited mutation at mRNA, protein and metabolic levels.
Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure.
Triosephosphate isomerase deficiency: facts and doubts.
Triosephosphate isomerase deficiency: haemolytic anaemia, myopathy with altered mitochondria and mental retardation due to a new variant with accelerated enzyme catabolism and diminished specific activity.
Triosephosphate isomerase deficiency: historical perspectives and molecular aspects.
Triosephosphate isomerase deficiency: New insights into an enigmatic disease.
Triosephosphate isomerase deficiency: predictions and facts.
Triosephosphate isomerase deficiency: repetitive occurrence of point mutation in amino acid 104 in multiple apparently unrelated families.
[A case of congenital non-spherocytic hemolytic anemia caused by triose phosphate isomerase deficiency. Prenatal diagnosis]
[Congenital hemolytic anemia due to triosephosphate isomerase deficiency]
[Deficiency of triosephosphate isomerase. Apropos of 2 new cases]
[Triosephosphate isomerase deficiency. Apropos of a new case]
[Triosephosphate isomerase deficiency. Familial survey and prenatal detection]
Tuberculosis
Biochemical and functional characterization of triosephosphate isomerase from Mycobacterium tuberculosis H37Rv.
Structural and functional characterization of Mycobacterium tuberculosis triosephosphate isomerase.
Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection.
Virus Diseases
Dynamics of the Interaction between Cotton Bollworm Helicoverpa armigera and Nucleopolyhedrovirus as Revealed by Integrated Transcriptomic and Proteomic Analyses.
Haemolysis in hepatitis A virus infections coinciding with the occurrence of autoantibodies against triosephosphate isomerase and the reactivation of latent persistent Epstein-Barr virus infection.
Hemolysis and autoantibodies to triosephosphate isomerase in a patient with acute hepatitis A virus infection.
The compound packaged in virions is the key to trigger host glycolysis machinery for virus life cycle in the cytoplasm.
Werner Syndrome
Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts.