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Reference on EC 5.1.3.7 - UDP-N-acetylglucosamine 4-epimerase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nishikawa, J.; Iwawaki, H.; Takubo, Y.; Nishihara, T.; Kondo, M.
Appearance of uridine 5'-diphospho-N-acetylglucosamine-4-epimerase during sporulation of Bacillus megaterium
Microbiol. Immunol.
30
1085-1093
1986
Priestia megaterium
Manually annotated by BRENDA team
Kingsley, D.M.; Kozarsky, K.F.; Hobbie, L.; Krieger, M.
Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant
Cell
44
749-759
1986
Cricetulus griseus
Manually annotated by BRENDA team
Yamamoto, K.; Kondo, Y.; Kumagai, H.; Tochikura, T.
Purification and some properties of UDP-N-acetylglucosamine 4-epimerase from Bacillus subtilis
Agric. Biol. Chem.
49
603-609
1985
Bacillus subtilis
-
Manually annotated by BRENDA team
Piller, F.; Eckhardt, A.E.; Hill, R.L.
The preparation of UDP-N-acetylgalactosamine from UDP-N-acetylglucosamine employing UDP-N-acetylglucosamine-4-epimerase
Anal. Biochem.
127
171-177
1982
Sus scrofa
Manually annotated by BRENDA team
Yamamoto, K.; Kawai, H.; Tochikura, T.
Preparation of uridine diphosphate-N-acetylgalactosamine from uridine diphosphate-N-acetylglucosamine by using microbial enzymes
Appl. Environ. Microbiol.
41
392-395
1981
Bacillus subtilis
Manually annotated by BRENDA team
Glowacka, D.; Zwierz, K.; Gindzienski, A.; Galasinski, W.
The metabolism of UDP-N-acetyl-D-glucosamine in the human gastric mucous membrane. II. The activity of UDP-N-acetylglucosamine 4-epimerase (E.C. 5.1.3.7)
Biochem. Med.
19
202-210
1978
Homo sapiens
Manually annotated by BRENDA team
Hiatt, W.R.; Whiteley, H.R.
Activity of uridine diphosphate N-acetylglucosamine-4-epimerase during spherulation of Physarum polycephalum
J. Bacteriol.
118
761-763
1974
Physarum polycephalum
Manually annotated by BRENDA team
Davidson, E.A.
UDP-N-acetyl-D-glucosamine 4-epimerase
Methods Enzymol.
8
277-281
1966
Gallus gallus
-
Manually annotated by BRENDA team
Glaser, L.
The biosynthesis of N-acetylgalactosamine
J. Biol. Chem.
234
2801-2805
1959
Bacillus subtilis
Manually annotated by BRENDA team
Estrela, A.I.; Pooley, H.M.; de Lencastre, H.; Karamata, D.
Genetic and biochemical characterization of Bacillus subtilis 168 mutants specifically blocked in the synthesis of the teichoic acid poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate): gneA, a new locus, is associated with UDP-N-acetylglucosamine 4-epimerase activity
J. Gen. Microbiol.
137
943-950
1991
Bacillus subtilis
Manually annotated by BRENDA team
Macechko, P.T.; Steimle, P.A.; Lindmark, D.G.; Erlandsen, S.L.; Jarroll, E.L.
Galactosamine-synthesizing enzymes are induced when Giardia encysts
Mol. Biochem. Parasitol.
56
301-310
1992
Giardia intestinalis
Manually annotated by BRENDA team
Hutton, C.W.; Corfield, A.P.; Clamp, J.R.; Dieppe, P.A.
The gut in the acute response: changes in colonic and hepatic enzyme activity in response to dermal inflammation in the rat
Clin. Sci.
73
165-169
1987
Rattus norvegicus
Manually annotated by BRENDA team
Kosaka, N.; Tanaka, H.; Ishii, A.; Shuto, K.
Effect of 5-[2-(diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4-b]pyridine trihydrochloride (KW-5805) on the biosynthesis of rat gastric mucus
Nippon Yakurigaku Zasshi
104
459-468
1994
Rattus norvegicus
Manually annotated by BRENDA team
Degeest, B.; Vaningelgem, F.; Laws, A.P.; De Vuyst, L.
UDP-N-acetylglucosamine 4-epimerase activity indicates the presence of N-acetylgalactosamine in exopolysaccharides of Streptococcus thermophilus strains
Appl. Environ. Microbiol.
67
3976-3984
2001
Streptococcus thermophilus
Manually annotated by BRENDA team
Winans, K.A.; Bertozzi, C.R.
An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation
Chem. Biol.
9
113-129
2002
Homo sapiens
Manually annotated by BRENDA team
Creuzenet, C.; Belanger, M.; Wakarchuk, W.W.; Lam, J.S.
Expression, purification, and biochemical characterization of WbpP, a new UDP-GlcNAc C4 epimerase from Pseudomonas aeruginosa serotype O6
J. Biol. Chem.
275
19060-19067
2000
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Demendi, M.; Ishiyama, N.; Lam, J.S.; Berghuis, A.M.; Creuzenet, C.
Towards a better understanding of the substrate specificity of the UDP-N-acetylglucosamine C4 epimerase WbpP
Biochem. J.
389
173-180
2005
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Ishiyama, N.; Creuzenet, C.; Lam, J.S.; Berghuis, A.M.
Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aeruginosa: substrate specificity in udp-hexose 4-epimerases
J. Biol. Chem.
279
22635-22642
2004
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Bernatchez, S.; Szymanski, C.M.; Ishiyama, N.; Li, J.; Jarrell, H.C.; Lau, P.C.; Berghuis, A.M.; Young, N.M.; Wakarchuk, W.W.
A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni
J. Biol. Chem.
280
4792-4802
2005
Campylobacter jejuni
Manually annotated by BRENDA team
Lopez, A.B.; Sener, K.; Trosien, J.; Jarroll, E.L.; van Keulen, H.
UDP-N-acetylglucosamine 4-epimerase from the intestinal protozoan Giardia intestinalis lacks UDP-glucose 4-epimerase activity
J. Eukaryot. Microbiol.
54
154-160
2007
Giardia intestinalis (Q868I5), Giardia intestinalis
Manually annotated by BRENDA team
Valiente, E.; Jimenez, N.; Merino, S.; Tomas, J.M.; Amaro, C.
Vibrio vulnificus biotype 2 serovar E gne but not galE is essential for lipopolysaccharide biosynthesis and virulence
Infect. Immun.
76
1628-1638
2008
Vibrio vulnificus (Q7MH46), Vibrio vulnificus
Manually annotated by BRENDA team
Niou, Y.K.; Wu, W.L.; Lin, L.C.; Yu, M.S.; Shu, H.Y.; Yang, H.H.; Lin, G.H.
Role of galE on biofilm formation by Thermus spp.
Biochem. Biophys. Res. Commun.
390
313-318
2009
Thermus thermophilus
Manually annotated by BRENDA team
Dong, S.; Chesnokova, O.N.; Turnbough, C.L.; Pritchard, D.G.
Identification of the UDP-N-acetylglucosamine 4-epimerase involved in exosporium protein glycosylation in Bacillus anthracis
J. Bacteriol.
191
7094-7101
2009
Bacillus anthracis (Q81JK4), Bacillus anthracis
Manually annotated by BRENDA team
Bhatt, V.S.; Guo, C.Y.; Guan, W.; Zhao, G.; Yi, W.; Liu, Z.J.; Wang, P.G.
Altered architecture of substrate binding region defines the unique specificity of UDP-GalNAc 4-epimerases
Protein Sci.
20
856-866
2011
Plesiomonas shigelloides (Q7BJX9), Plesiomonas shigelloides O17 (Q7BJX9)
Manually annotated by BRENDA team
Beerens, K.; Soetaert, W.; Desmet, T.
Characterization and mutational analysis of the UDP-Glc(NAc) 4-epimerase from Marinithermus hydrothermalis
Appl. Microbiol. Biotechnol.
97
7733-7740
2013
Marinithermus hydrothermalis
Manually annotated by BRENDA team
Bhatt, V.S.; Guan, W.; Xue, M.; Yuan, H.; Wang, P.G.
Insights into role of the hydrogen bond networks in substrate recognition by UDP-GalNAc 4-epimerases
Biochem. Biophys. Res. Commun.
412
232-237
2011
Escherichia coli
Manually annotated by BRENDA team
Cunneen, M.M.; Liu, B.; Wang, L.; Reeves, P.R.
Biosynthesis of UDP-GlcNAc, UndPP-GlcNAc and UDP-GlcNAcA involves three easily distinguished 4-epimerase enzymes, Gne, Gnu and GnaB
PLoS ONE
8
e67646
2013
Escherichia coli, Yersinia pseudotuberculosis, Yersinia enterocolitica, Escherichia coli O157, Yersinia enterocolitica O:8, Escherichia coli O86, Yersinia pseudotuberculosis O6 and O7
Manually annotated by BRENDA team
Zhu, H.M.; Sun, B.; Li, Y.J.; Meng, D.H.; Zheng, S.; Wang, T.T.; Wang, F.S.; Sheng, J.Z.
KfoA, the UDP-glucose-4-epimerase of Escherichia coli strain O5 K4 H4, shows preference for acetylated substrates
Appl. Microbiol. Biotechnol.
102
751-761
2018
Escherichia coli (Q8L0V2), Escherichia coli ATCC 23502 / K4 (Q8L0V2)
Manually annotated by BRENDA team
Shin, S.; Choi, J.; Di Luccio, E.; Lee, Y.; Lee, S.; Lee, S.; Lee, S.; Lee, D.
The structural basis of substrate promiscuity in UDP-hexose 4-epimerase from the hyperthermophilic Eubacterium Thermotoga maritima
Arch. Biochem. Biophys.
585
39-51
2015
Thermotoga maritima (Q9WYX9), Thermotoga maritima DSM 3109 (Q9WYX9), Thermotoga maritima ATCC 43589 / MSB8 / DSM 3109 / JCM 10099 (Q9WYX9)
Manually annotated by BRENDA team
Wen, Y.; Qin, J.; Deng, Y.; Wang, H.; Magdalou, J.; Chen, L.
The critical role of UDP-galactose-4-epimerase in osteoarthritis modulating proteoglycans synthesis of the articular chondrocytes
Biochem. Biophys. Res. Commun.
452
906-911
2014
Homo sapiens (Q14376)
Manually annotated by BRENDA team
Chen, L.L.; Han, D.L.; Zhai, Y.F.; Wang, J.H.; Wang, Y.F.; Chen, M.
Characterization and mutational analysis of two UDP-galactose 4-epimerases in Streptococcus pneumoniae TIGR4
Biochemistry (Moscow)
83
37-44
2018
Streptococcus pneumoniae (A0A0H2URG4), Streptococcus pneumoniae ATCC BAA-334 / TIGR4 (A0A0H2URG4)
Manually annotated by BRENDA team
Beerens, K.; Soetaert, W.; Desmet, T.
UDP-hexose 4-epimerases a view on structure, mechanism and substrate specificity
Carbohydr. Res.
414
8-14
2015
Plesiomonas shigelloides (Q7BJX9), Pseudomonas aeruginosa (Q8KN66)
Manually annotated by BRENDA team
Dadashipour, M.; Iwamoto, M.; Hossain, M.M.; Akutsu, J.I.; Zhang, Z.; Kawarabayasi, Y.
Identification of a direct biosynthetic pathway for UDP-N-acetylgalactosamine from glucosamine-6-phosphate in thermophilic crenarchaeon Sulfolobus tokodaii
J. Bacteriol.
200
e00048-18
2018
no activity in Sulfolobus tokodaii
Manually annotated by BRENDA team