Information on EC 5.1.3.10 - CDP-paratose 2-epimerase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
5.1.3.10
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RECOMMENDED NAME
GeneOntology No.
CDP-paratose 2-epimerase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CDP-alpha-D-paratose = CDP-alpha-D-tyvelose
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
epimerization
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Amino sugar and nucleotide sugar metabolism
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CDP-tyvelose biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
CDP-3,6-dideoxy-D-glucose 2-epimerase
Requires NAD+.
CAS REGISTRY NUMBER
COMMENTARY hide
37318-36-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Salmonella durban
mutant strains defective in CDP-D-abequose 2-epimerase activity
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CDP-3,6-dideoxy-D-glucose
CDP-3,6-dideoxy-D-mannose
show the reaction diagram
additional information
?
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Salmonella durban
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biosynthesis of CDP-dideoxyhexoses. The specific O-antigen factors of group A and D1 Salmonella i.e. O-2 and O-9 factors, are related to 3,6-dideoxy-D-glucose and 3,6-dideoxy-D-mannose respectively
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
Salmonella durban
-
biosynthesis of CDP-dideoxyhexoses. The specific O-antigen factors of group A and D1 Salmonella i.e. O-2 and O-9 factors, are related to 3,6-dideoxy-D-glucose and 3,6-dideoxy-D-mannose respectively
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7 - 11.8
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7.0: about 35% of maximal activity, 11.8: about 40% of maximal activity
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Show AA Sequence (118 entries)
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