Information on EC 4.4.1.33 - R-phycocyanin alpha-cysteine-84 phycourobilin lyase/isomerase

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The expected taxonomic range for this enzyme is: Synechococcus

EC NUMBER
COMMENTARY hide
4.4.1.33
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RECOMMENDED NAME
GeneOntology No.
R-phycocyanin alpha-cysteine-84 phycourobilin lyase/isomerase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[R-phycocyanin alpha-subunit]-Cys84-phycourobilin = apo-[R-phycocyanin alpha-subunit] + (2R,3E)-phycoerythrobilin
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
phycourobilin biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
[R-phycocyanin alpha-subunit]-Cys84-phycourobilin:(2R,3E)-phycoerythrobilin lyase/isomerase
The enzyme, characterized from the cyanobacterium Synechococcus sp. WH8102, catalyses the covalent attachment of the phycobilin chromophore phycoerythrobilin to cysteine 84 of the alpha subunit of the phycobiliprotein R-phycocyanin and its isomerization to phycourobilin.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
apo-[R-phycocyanin alpha-subunit] + (3E)-phycoerythrobilin
[R-phycocyanin alpha-subunit]-Cys84-phycourobilin
show the reaction diagram
apo-[R-phycoerythrocyanin alpha-subunit] + phycocyanobilin
[R-phycocyanin alpha-subunit]-Cys84-phycoviolobilin
show the reaction diagram
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the enzyme does not use phycocyanobilin in natural conditions because no phycoviolobilin is observed in Synechococcus sp. WH8102 or any other rpcG-containing strain
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?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
apo-[R-phycocyanin alpha-subunit] + (3E)-phycoerythrobilin
[R-phycocyanin alpha-subunit]-Cys84-phycourobilin
show the reaction diagram
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
monomer
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE