Information on EC 4.2.3.137 - (E)-2-epi-beta-caryophyllene synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Selaginella moellendorffii

EC NUMBER
COMMENTARY
4.2.3.137
-
RECOMMENDED NAME
GeneOntology No.
(E)-2-epi-beta-caryophyllene synthase
-
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
(2E,6E)-farnesyl diphosphate = (E)-2-epi-beta-caryophyllene + diphosphate
show the reaction diagram
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Sesquiterpenoid and triterpenoid biosynthesis
-
SYSTEMATIC NAME
IUBMB Comments
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (E)-2-epi-beta-caryophyllene-forming)
Isolated from the plant Selaginella moellendorfii. The enzyme also gives two other sesquiterpenoids.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
2-epi-(E)-beta-caryophyllene synthase
-
-
-
-
SmMTPSL26
-
-
-
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate
(E)-2-epi-beta-caryophyllene + diphosphate
show the reaction diagram
-
enzyme shows sesquiterpene synthase activity in vitro. SmMTPSL26 produces three sesquiterpene products that are specific to this enzyme (2-epi-(E)-beta-caryophyllene and unidentified sesquiterpene). SmMTPSL26 does not show diterpene synthase activity
-
-
?
Cloned/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
expressed in Escherichia coli
-