Information on EC 4.2.1.73 - Protoaphin-aglucone dehydratase (cyclizing)

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
4.2.1.73
-
RECOMMENDED NAME
GeneOntology No.
Protoaphin-aglucone dehydratase (cyclizing)
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Protoaphin aglucone = xanthoaphin + H2O
show the reaction diagram
the product is converted nonenzymatically to erythroaphin, an aphid pigment
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
elimination
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)
The product is converted non-enzymically to erythroaphin, an aphid pigment.
CAS REGISTRY NUMBER
COMMENTARY hide
64177-87-3
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
Dactynotus jaceae
-
-
-
Manually annotated by BRENDA team
Hausmann, wolly aphid, hemiptera
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Protoaphin aglucone
?
show the reaction diagram
-
protoaphins occur in the hemolymph of the insects and are responsible for the dark color of their bodies
-
-
-
Protoaphin aglucone
Xanthoaphin + H2O
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Protoaphin aglucone
?
show the reaction diagram
-
protoaphins occur in the hemolymph of the insects and are responsible for the dark color of their bodies
-
-
-
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Naphthoresorcinol
-
i.e. 1,3-dihydroxynaphthalene
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.6
-
enzyme assay at
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
20 - 22
-
enzyme assay at
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
120000
-
analytical ultracentrifugation
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
monomer
-
1 * 130000-140000, overestimation of MW in SDS-PAGE is caused by glucosamine residues
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
side-chain modification
-
14-15 glucosamine residues per mol of protein
ORGANIC SOLVENT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Butanol
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE