Information on EC 4.2.1.161 - bisanhydrobacterioruberin hydratase

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The expected taxonomic range for this enzyme is: Haloarcula japonica

EC NUMBER
COMMENTARY hide
4.2.1.161
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RECOMMENDED NAME
GeneOntology No.
bisanhydrobacterioruberin hydratase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
bacterioruberin = bisanhydrobacterioruberin + 2 H2O
show the reaction diagram
bacterioruberin = monoanhydrobacterioruberin + H2O
show the reaction diagram
monoanhydrobacterioruberin = bisanhydrobacterioruberin + H2O
show the reaction diagram
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
carotenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
bacterioruberin hydro-lyase (bisanhydrobacterioruberin-forming)
The enzyme, isolated from the archaeon Haloarcula japonica, is involved in the biosynthesis of the C50 carotenoid bacterioruberin. In this pathway it catalyses the introduction of hydroxyl groups to C3'' and C3''' of bisanhydrobacterioruberin to generate bacterioruberin.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
the deletion mutant strain DELTAc0505 shows the same growth rate as wild-type strain. The main cartotenoid products of the mutant strain are monoanhydrobacterioruberin and bisanhydrobacterioruberin. When plasmid pJc0505 containing the intact c0505 gene is introduced into the DELTAc0507 strain, the transformant restores the production of bacterioruberin
metabolism
the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
bisanhydrobacterioruberin + 2 H2O
bacterioruberin
show the reaction diagram
bisanhydrobacterioruberin + H2O
monoanhydrobacterioruberin
show the reaction diagram
monoanhydrobacterioruberin + H2O
bacterioruberin
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
bisanhydrobacterioruberin + 2 H2O
bacterioruberin
show the reaction diagram
A0A0A1GNF2
the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin. It introduced hydroxyl groups to C3'' and C3''' of bisanhydrobacterioruberin to generate bacterioruberin
-
-
?
bisanhydrobacterioruberin + H2O
monoanhydrobacterioruberin
show the reaction diagram
A0A0A1GNF2
the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin
-
-
?
monoanhydrobacterioruberin + H2O
bacterioruberin
show the reaction diagram
A0A0A1GNF2
the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin
-
-
?