Information on EC 4.2.1.132 - 2-hydroxyhexa-2,4-dienoate hydratase

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The expected taxonomic range for this enzyme is: Comamonas testosteroni

EC NUMBER
COMMENTARY hide
4.2.1.132
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RECOMMENDED NAME
GeneOntology No.
2-hydroxyhexa-2,4-dienoate hydratase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-hydroxy-2-oxohexanoate = (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H2O
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
androstenedione degradation
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Metabolic pathways
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Microbial metabolism in diverse environments
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Xylene degradation
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androgen and estrogen metabolism
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SYSTEMATIC NAME
IUBMB Comments
(2Z,4Z)-2-hydroxyhexa-2,4-dienoate hydro-lyase
This enzyme catalyses a late step in the bacterial steroid degradation pathway. The product, 4-hydroxy-2-oxohexanoate, forms a 2-hydroxy-4-hex-2-enolactone under acidic conditions.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
formerly Pseudomonas testosteroni, strain TA441, gene tesE
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Manually annotated by BRENDA team
formerly Pseudomonas testosteroni, strain TA441, gene tesE
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O
4-hydroxy-2-oxohexanoic acid
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O
4-hydroxy-2-oxohexanoic acid
show the reaction diagram
Show AA Sequence (101 entries)
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