Information on EC 4.2.1.128 - lupan-3beta,20-diol synthase

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The expected taxonomic range for this enzyme is: Arabidopsis thaliana

EC NUMBER
COMMENTARY
4.2.1.128
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RECOMMENDED NAME
GeneOntology No.
lupan-3beta,20-diol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
lupan-3beta,20-diol = (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
show the reaction diagram
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-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Sesquiterpenoid and triterpenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (lupan-3beta,20-diol forming)
The reaction occurs in the reverse direction. The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3beta,20-diol with small amounts of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol. See EC 5.4.99.41 (lupeol synthase).
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
Q9C5M3
-
-
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
-
-
-
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
Q9C5M3
the recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3beta,20-diol with small amounts of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
Q9C5M3
-
-
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
-
-
-
-
?