Information on EC 4.2.1.128 - lupan-3beta,20-diol synthase

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The expected taxonomic range for this enzyme is: Arabidopsis thaliana

EC NUMBER
COMMENTARY
4.2.1.128
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RECOMMENDED NAME
GeneOntology No.
lupan-3beta,20-diol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
lupan-3beta,20-diol = (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
show the reaction diagram
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-
-
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PATHWAY
KEGG Link
MetaCyc Link
Sesquiterpenoid and triterpenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (lupan-3beta,20-diol forming)
The reaction occurs in the reverse direction. The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3beta,20-diol with small amounts of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol. See EC 5.4.99.41 (lupeol synthase).
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
At1g78970
Q9C5M3
gene name
LUP1
Q9C5M3
gene name
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
Q9C5M3
-
-
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
-
-
-
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
Q9C5M3
the recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3beta,20-diol with small amounts of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
Q9C5M3
-
-
-
?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
lupan-3beta,20-diol
show the reaction diagram
-
-
-
-
?