Reference on EC 4.1.3.44 - tRNA 4-demethylwyosine synthase (AdoMet-dependent)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Noma, A.; Kirino, Y.; Ikeuchi, Y.; Suzuki, T.
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA
EMBO J.
25
2142-2154
2006
Saccharomyces cerevisiae (Q08960), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (Q08960)
Goto-Ito, S.; Ishii, R.; Ito, T.; Shibata, R.; Fusatomi, E.; Sekine, S.I.; Bessho, Y.; Yokoyama, S.
Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis
Acta Crystallogr. Sect. D
63
1059-1068
2007
Pyrococcus horikoshii (O59412), Pyrococcus horikoshii DSM 12428 (O59412)
Young, A.P.; Bandarian, V.
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine
Biochemistry
50
10573-10575
2011
Methanocaldococcus jannaschii (Q57705), Methanocaldococcus jannaschii ATCC 43067 (Q57705)
Perche-Letuvee, P.; Kathirvelu, V.; Berggren, G.; Clemancey, M.; Latour, J.M.; Maurel, V.; Douki, T.; Armengaud, J.; Mulliez, E.; Fontecave, M.; Garcia-Serres, R.; Gambarelli, S.; Atta, M.
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate
J. Biol. Chem.
287
41174-41185
2012
Pyrococcus abyssi (Q9V1F9), Pyrococcus abyssi, Pyrococcus abyssi GE5 / CNCM I-1302 / DSM 25543 (Q9V1F9)
Suzuki, Y.; Noma, A.; Suzuki, T.; Senda, M.; Senda, T.; Ishitani, R.; Nureki, O.
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA
J. Mol. Biol.
372
1204-1214
2007
Saccharomyces cerevisiae (Q08960), Methanocaldococcus jannaschii (Q57705), Methanocaldococcus jannaschii DSM 2661 (Q57705), Saccharomyces cerevisiae ATCC 204508 (Q08960)
Young, A.; Bandarian, V.
Mechanistic studies of the radical S-adenosyl-L-methionine enzyme 4-demethylwyosine synthase reveal the site of hydrogen atom abstraction
Biochemistry
54
3569-3572
2015
Methanocaldococcus jannaschii
-
Kathirvelu, V.; Perche-Letuvee, P.; Latour, J.; Atta, M.; Forouhar, F.; Gambarelli, S.; Garcia-Serres, R.
Spectroscopic evidence for cofactor-substrate interaction in the radical-SAM enzyme TYW1
Dalton Trans.
46
13211-13219
2017
Methanocaldococcus jannaschii (Q57705)
Grell, T.; Young, A.; Drennan, C.; Bandarian, V.
Biochemical and structural characterization of a Schiff Base in the radical-mediated biosynthesis of 4-demethylwyosine by TYW1
J. Am. Chem. Soc.
140
6842-6852
2018
Methanocaldococcus jannaschii (Q57705), Methanocaldococcus jannaschii DSM 2661 (Q57705)
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