Reference on EC 4.1.2.14 - 2-dehydro-3-deoxy-phosphogluconate aldolase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Meloche, H.P.; Wood, W.A.
Crystallization and characteristics of 2-keto-3-deoxy-6-phosphogluconic aldolase
J. Biol. Chem.
239
3515-3518
1964
Pelomonas saccharophila, Pseudomonas fluorescens
Meloche, H.P.; Ingram, J.M.; Wood, W.A.
2-Keto-3-deoxy-6-phosphogluconic aldolase (crystalline)
Methods Enzymol.
9
520-524
1966
Pseudomonas fluorescens
-
Meloche, H.P.
Bromopyruvate inactivation of 2-keto-3-deoxy-6-phosphogluconic aldolase. I. Kinetic evidence for active site specificity
Biochemistry
6
2273-2280
1967
Pelomonas saccharophila, Pelomonas saccharophila A 3.12
Hammerstedt, R.H.; Mhler, H.; Decker, K.A.; Wood, W.A.
Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase. I. Physical evidence for a three-subunit molecule
J. Biol. Chem.
246
2069-2074
1971
Pseudomonas putida
Robertson, D.C.; Hammerstedt, R.H.; Wood, W.A.
Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase. II. Chemical evidence for a three-subunit molecule
J. Biol. Chem.
246
2075-2083
1971
Pseudomonas putida
Vandlen, R.L.; Ersfeld, D.L.; Tulinsky, A.; Wood, W.A.
Confirmation of a trimeric subunit arrangement for 2-keto-3-deoxy-6-phosphogluconic aldolase using X-ray crystallographic methods
J. Biol. Chem.
248
2251-2253
1973
Pseudomonas putida
Wood, W.A.
2-Keto-3-deoxy-6-phosphogluconic and related aldolases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
7
281-302
1972
Pseudomonas putida, Pelomonas saccharophila
-
Hammerstedt, R.H.; Mhler, H.; Decker, K.A.; Ehrsfeld, D.; Wood, W.A.
2-Keto-3-deoxy-6-phosphogluconic aldolase
Methods Enzymol.
42C
258-264
1975
Pseudomonas putida
-
Meloche, H.P.; Mehler, L.; Wurster, J.M.
The stereochemistry at carbon 3 of pyruvate lyase condensation products. 2-Keto-3-deoxygluconate-6-phosphate aldolase
J. Biol. Chem.
250
6870-6874
1975
Pseudomonas putida
Meloche, H.P.; Monti, C.T.
The stereochemistry, at carbon 3 of pyruvate lyase condensation products. 2-Keto-3-deoxygluconate-6-phosphate and 2-keto-3-deoxygalactonate-6-phosphate aldolase of Pseudomonas saccharophila
J. Biol. Chem.
250
6875-6879
1975
Pelomonas saccharophila
Monti, C.T.; Waterbor, J.W.; Meloche, H.P.
Interaction of the chiral pyruvate analog, 2-keto-3-bromobutyrate with pyruvate lyases. 2-Keto-3-deoxygluconate-6-phosphate aldolase of Pseudomonas putida
J. Biol. Chem.
254
5862-5865
1979
Pseudomonas putida
Suzuki, N.; Wood, W.A.
Complete primary structure of 2-keto-3-deoxy-6-phosphogluconate aldolase
J. Biol. Chem.
255
3427-3435
1980
Pseudomonas putida
Mavridis, I.M.; Hatada, M.H.; Tulinski, A.; Lebioda, L.
Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase at 2.8 A resolution
J. Mol. Biol.
162
419-444
1982
Pseudomonas putida
Scopes, R.K.
Use of differential dye-ligand chromatography with affinity elution for enzyme purification: 2-keto-3-deoxy-6-phosphogluconate aldolase from Zymomonas mobilis
Anal. Biochem.
136
525-529
1984
Zymomonas mobilis
Knappmann, B.R.; Steigel, A.; Kula, M.R.
Investigation of 2-oxo-3-deoxy-5-phosphogluconate aldolase from Zymomonas mobilis as a catalyst in organic synthesis
Biotechnol. Appl. Biochem.
22
107-120
1995
Zymomonas mobilis
-
Shuttleworth, K.L.; Unz, R.F.; Wichlacz, P.L.
Glucose catabolism in strains of acidophilic, heterotrophic bacteria
Appl. Environ. Microbiol.
50
573-579
1985
Acidiphilium cryptum
Chakrabarti, S.K.; Mishra, A.K.; Chakrabartty, P.K.
Metabolism of glucose and gluconate in fast- and slow-growing rhizobia
Phytochemistry
26
85-87
1987
Bradyrhizobium japonicum, Mesorhizobium loti, Rhizobium leguminosarum, Bradyrhizobium lupini, Sinorhizobium meliloti, Rhizobium phaseoli, Rhizobium sp., Rhizobium leguminosarum SU391, Rhizobium phaseoli CC365, Bradyrhizobium lupini RL3001, Sinorhizobium meliloti SU216, Bradyrhizobium japonicum CC409, Rhizobium leguminosarum CC224, Mesorhizobium loti NZP2213
-
Shelton, M.C.; Toone, E.J.
Differential dye-ligand chromatography as a general purification protocol for 2-keto-3-deoxy-6-phosphogluconate aldolases
Tetrahedron
6
207-211
1995
Escherichia coli, Pseudomonas putida, Pelomonas saccharophila, Zymomonas mobilis
-
Mendz, G.L.; Hazell, S.L.; Burns, B.P.
The Entner-Doudoroff pathway in Helicobacter pylori
Arch. Biochem. Biophys.
312
349-356
1994
Helicobacter pylori
Taha, T.S.; Deits, T.L.
Purification and characterization of 2-keto-3-deoxy-6-phosphogluconate aldolase from Azotobacter vinelandii: evidence that the enzyme is bifunctional towards 2-keto-4-hydroxyglutarate cleavage
Biochem. Biophys. Res. Commun.
200
459-466
1994
Azotobacter vinelandii
Conway, T.; Fliege, R.; Jones-Kilpatrick, D.; Liu, J.; Barnell, W.O.; Egan, S.E.
Cloning, characterization and expression of the Zymomonas mobilis eda gene that encodes 2-keto-3-deoxy-6-phosphogluconate aldolase of the Entner-Doudoroff pathway
Mol. Microbiol.
5
2901-2911
1991
Zymomonas mobilis
Griffiths, J.S.; Wymer, N.J.; Njolito, E.; Niranjanakumari, S.; Fierke, C.A.; Toone, E.J.
Cloning, Isolation and Characterization of the Thermotoga Maritima KDPG aldolase
Bioorg. Med. Chem.
10
545-550
2002
Thermotoga maritima
Buchanan, L.V.; Mehta, N.; Pocivavsek, L.; Niranjanakumari, S.; Toone, E.J.; Naismith, J.H.
Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli
Acta Crystallogr. Sect. D
55
1946-1948
1999
Escherichia coli
Bell, B.J.; Watanabe, L.; Rios-Steiner, J.L.; Tulinsky, A.; Lebioda, L.; Arni, R.K.
Structure of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase from Pseudomonas putida
Acta Crystallogr. Sect. D
59
1454-1458
2003
Pseudomonas putida
Fong, S.; Machajewski, T.D.; Mak, C.C.; Wong, C.
Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars
Chem. Biol.
7
873-883
2000
Escherichia coli
Allard, J.; Grochulski, P.; Sygusch, J.
Covalent intermediate trapped in 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase structure at 1.95-A resolution
Proc. Natl. Acad. Sci. USA
98
3679-3684
2001
Escherichia coli (P0A955)
Wymer, N.; Buchanan, L.V.; Henderson, D.; Mehta, N.; Botting, C.H.; Pocivavsek, L.; Fierke, C.A.; Toone, E.J.; Naismith, J.H.
Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli
Structure
9
1-9
2001
Escherichia coli (P0A955), Escherichia coli
Braga, R.; Hecquet, L.; Blonski, C.
Slow-binding inhibition of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase
Bioorg. Med. Chem.
12
2965-2972
2004
Escherichia coli
Fullerton, S.W.B.; Griffiths, J.S.; Merkel, A.B.; Cheriyan, M.; Wymer, N.J.; Hutchins, M.J.; Fierke, C.A.; Toone, E.J.; Naismith, J.H.
Mechanism of the class I KDPG aldolase
Bioorg. Med. Chem.
14
3002-3010
2006
Escherichia coli, Thermotoga maritima
Theodossis, A.; Walden, H.; Westwick, E.J.; Connaris, H.; Lamble, H.J.; Hough, D.W.; Danson, M.J.; Taylor, G.L.
The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus
J. Biol. Chem.
279
43886-43892
2004
Saccharolobus solfataricus
Voss, I.; Steinbchel, A.
Application of a KDPG-aldolase gene-dependent addiction system for enhanced production of cyanophycin in Ralstonia eutropha strain H16
Metab. Eng.
8
66-78
2006
Cupriavidus necator, Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
Walters, M.J.; Srikannathasan, V.; McEwan, A.R.; Naismith, J.H.; Fierke, C.A.; Toone, E.J.
Characterization and crystal structure of Escherichia coli KDPGal aldolase
Bioorg. Med. Chem.
16
710-720
2008
Escherichia coli
Selby, C.P.; Sancar, A.
A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity
Proc. Natl. Acad. Sci. USA
103
17696-17700
2006
Thermotoga maritima
Cheriyan, M.; Toone, E.J.; Fierke, C.A.
Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates
Protein Sci.
16
2368-2377
2007
Escherichia coli
Zhang, Q.; Gao, F.; Qi, J.; Cheng, H.; Liu, Y.; Gao, G.F.
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase from Streptococcus suis serotype 2
Acta Crystallogr. Sect. F
64
997-999
2008
Streptococcus suis (A4VVI7)
Ishikawa, K.; Gunji, Y.; Yasueda, H.; Asano, K.
Improvement of L-lysine production by Methylophilus methylotrophus from methanol via the Entner-Doudoroff pathway, originating in Escherichia coli
Biosci. Biotechnol. Biochem.
72
2535-2542
2008
Escherichia coli
Pauluhn, A.; Ahmed, H.; Lorentzen, E.; Buchinger, S.; Schomburg, D.; Siebers, B.; Pohl, E.
Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax
Proteins
72
35-43
2008
Saccharolobus solfataricus, Thermoproteus tenax (Q704D1), Thermoproteus tenax
Ryu, H.C.; Park, S.Y.; Lee, S.H.; Kim, J.S.
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of 2-keto-3-deoxy-6-phosphogluconate aldolase from Zymomonas mobilis ZM4
Acta Crystallogr. Sect. F
66
471-473
2010
Zymomonas mobilis, Zymomonas mobilis ZM4
Harada, E.; Iida, K.I.; Shiota, S.; Nakayama, H.; Yoshida, S.I.
Glucose metabolism in Legionella pneumophila: dependence on the Entner-Doudoroff pathway and connection with intracellular bacterial growth
J. Bacteriol.
192
2892-2899
2010
Legionella pneumophila
Lin, K.; Elbahloul, Y.; Steinbuechel, A.
Physiological conditions conducive to high cell density and high cyanophycin content in Ralstonia eutropha strain H16 possessing a KDPG aldolase gene-dependent addiction system
Appl. Microbiol. Biotechnol.
93
1885-1894
2012
Cupriavidus necator (Q0K1X1), Cupriavidus necator, Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1 (Q0K1X1)
Cheriyan, M.; Toone, E.J.; Fierke, C.A.
Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates
Biochemistry
51
1658-1668
2012
Escherichia coli
Schapfl, M.; Baier, S.; Fries, A.; Ferlaino, S.; Waltzer, S.; Mueller, M.; Sprenger, G.A.
Extended substrate range of thiamine diphosphate-dependent MenD enzyme by coupling of two C-C-bonding reactions
Appl. Microbiol. Biotechnol.
102
8359-8372
2018
Escherichia coli (P0A955)
Zaitsev, V.; Johnsen, U.; Reher, M.; Ortjohann, M.; Taylor, G.L.; Danson, M.J.; Schoenheit, P.; Crennell, S.J.
Insights into the substrate specificity of archaeal Entner-Doudoroff aldolases the structures of Picrophilus torridus 2-keto-3-deoxygluconate aldolase and Sulfolobus solfataricus 2-keto-3-deoxy-6-phosphogluconate aldolase in complex with 2-keto-3-deoxy-6
Biochemistry
57
3797-3806
2018
Saccharolobus solfataricus (O54288), Saccharolobus solfataricus
Sutter, J.M.; Taestensen, J.B.; Johnsen, U.; Soppa, J.; Schoenheit, P.
Key enzymes of the semiphosphorylative Entner-Doudoroff pathway in the haloarchaeon Haloferax volcanii characterization of glucose dehydrogenase, gluconate dehydratase, and 2-keto-3-deoxy-6-phosphogluconate aldolase
J. Bacteriol.
198
2251-2262
2016
Haloferax volcanii (D4GV57), Haloferax volcanii, Haloferax volcanii H26 (D4GV57)
Morita, K.; Nomura, Y.; Ishii, J.; Matsuda, F.; Kondo, A.; Shimizu, H.
Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner-Doudoroff pathway in Saccharomyces cerevisiae for improvement of isobutanol production
J. Biosci. Bioeng.
124
263-270
2017
Escherichia coli (P0A955)
Seo, P.W.; Ryu, H.C.; Gu, D.H.; Park, H.S.; Park, S.Y.; Kim, J.S.
Structures of Zymomonas 2-keto-3-deoxy-6-phosphogluconate aldolase with and without a substrate analog at the phosphate-binding loop
J. Microbiol. Biotechnol.
28
1339-1345
2018
Zymomonas mobilis subsp. mobilis (Q00384), Zymomonas mobilis subsp. mobilis ATCC 31821 (Q00384)
html completed
