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EC Tree
IUBMB Comments Also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.
The taxonomic range for the selected organisms is: Schistosoma mansoni The enzyme appears in selected viruses and cellular organisms
Synonyms
aldolase, aldolase a, aldolase b, aldolase c, aldoa, fructose-1,6-bisphosphate aldolase, fructose-bisphosphate aldolase, aldob, fructose bisphosphate aldolase, fructose 1,6-bisphosphate aldolase,
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fructose 1,6 bisphosphate aldolase
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1,6-Diphosphofructose aldolase
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37 kDa major allergen
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aldolase, fructose diphosphate
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Brain-type aldolase
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Diphosphofructose aldolase
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Fructose 1,6-bisphosphate aldolase
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Fructose 1,6-diphosphate aldolase
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Fructose 1-monophosphate aldolase
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Fructose 1-phosphate aldolase
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Fructose bisphosphate aldolase
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Fructose diphosphate aldolase
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Fructose-1,6-bisphosphate triosephosphate-lyase
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IgE-binding allergen
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ketose 1-phosphate aldolase
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Liver-type aldolase
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Muscle-type aldolase
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Phosphofructoaldolase
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-, -, -, -, -, -, -, -, -, -, -, -, -, -, -, -
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D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)
Also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.
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D-fructose 1,6-bisphosphate
glycerone phosphate + D-glyceraldehyde 3-phosphate
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UniProt
brenda
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ALF_SCHMA
363
0
39645
Swiss-Prot
other Location (Reliability: 2 )
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glutathione Sepharose 4B, electro elution procedure
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expressed in Escherichia coli as a fusion protein (GST/P44)
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El-Dabaa, E.; El-Sayed, A.; Karim, A.M.; Eldesoky, H.M.; Fahim, F.A.; LoVerde, P.T.; Saber, M.A.
Cloning and characterization of Schistosoma mansoni fructose-1,6-bisphosphate aldolase isoenzyme
J. Parasitol.
84
954-960
1998
Schistosoma mansoni
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Marques, H.H.; Zouain, C.S.; Torres, C.B.; Oliveira, J.S.; Alves, J.B.; Goes, A.M.
Protective effect and granuloma down-modulation promoted by RP44 antigen a fructose 1,6 bisphosphate aldolase of Schistosoma mansoni
Immunobiology
213
437-446
2008
Schistosoma mansoni (P53442), Schistosoma mansoni
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