A pyridoxal-phosphate protein. This enzyme is unable to decarboxylate the D-isomer of threonine O-3-phosphate. The product of this reaction, (R)-1-aminopropan-2-yl phosphate, is the substrate of EC 126.96.36.199, adenosylcobinamide-phosphate synthase, which converts adenosylcobyric acid into adenosylcobinamide phosphate in the anaerobic cobalamin biosynthesis pathway.
enzyme shows stereospecificity for the L-isomer, unable to decarboxylate the D-isomer, adenosylcobalamin biosynthesis, end product of the corrin ring biosynthetic pathway is 5'-deoxyadenosylcobinamide phosphate, not 5'-deoxyadenosylcobinamide
crystals belong to space group I222 with unit cell dimensions a : 66.6 A, b : 103.2 A, and c : 117.1 A, apo-CobD crystals belong to space group I222 with unit cell dimensions a : 76.0 A, b : 103.3 A, and c : 109.3 A