Information on EC 4.1.1.56 - 3-oxolaurate decarboxylase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
4.1.1.56
-
RECOMMENDED NAME
GeneOntology No.
3-oxolaurate decarboxylase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-oxododecanoate = 2-undecanone + CO2
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
decarboxylation
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
2-methylketone biosynthesis
-
-
SYSTEMATIC NAME
IUBMB Comments
3-oxododecanoate carboxy-lyase (2-undecanone-forming)
Also decarboxylates other C14 to C16 oxo acids.
CAS REGISTRY NUMBER
COMMENTARY hide
37290-49-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain 311
-
-
Manually annotated by BRENDA team
strain 311
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-Oxododecanoate
2-Undecanone + CO2
show the reaction diagram
3-Oxododecanoate
?
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
3-Oxododecanoate
?
show the reaction diagram
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 10
-
pH 5.0: about 25% of maximal activity, pH 10.0: about 50% of maximal activity
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
resting and germinating
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1
-
15 min, 21°C, about 40% loss of activity
4718
3
-
15 min, 21°C, about 20% loss of activity
4718
5 - 7
-
15 min, 21°C, stable
4718
8
-
15 min, 21°C, about 5% loss of activity
4718
9
-
15 min, 21°C, about 20% loss of activity
4718
10
-
15 min, 21°C, about 50% loss of activity
4718
11
-
15 min, 21°C, complete loss of activity
4718
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
half-life: 31 min
35
-
half-life: 6 min
40
-
half-life: 2.5 min
100
-
about 10% loss of activity after 30 min, about 25% loss of activity after 60 min, about 50% loss of activity after 90 min, enzyme in crude extract
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
dialysis against water, at 14°C, 30% loss of activity
-
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, stable for 2 months
-
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE