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Synonyms
acmsd, aminocarboxymuconate-semialdehyde decarboxylase, alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, picolinic carboxylase, acmsdase, hacmsd, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, acmsd i, acms decarboxylase, alpha-amino-beta-carboxymuconic-epsilon-semialdehyde decarboxylase,
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2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
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2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
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?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
additional information
?
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key enzyme in NAD biosynthesis from tryptophan
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
important enzyme regulating tryptophan-niacin metabolism
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
tryptophan-niacine pathway
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
key enzyme in the regulation of the tryptophan-nicotinamide adenine dinucleotide pathway
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
suppression of the enzyme activity by linoleic acid in relation to its induction by glucocorticoids and dietary protein
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
expression level of EC 4.1.1.45 might by modulated by linoleic acid or its metabolites
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
effect of dietary protein and soybean oil which contains about 85% unsaturated fatty acids
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
directly related to the concentration of blood muconate
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
key enzyme of niacin synthesis from Trp
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
effect of various dietary fatty acids on enzyme activity
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
40% casein diet, nicotinic acid-free, significantly reduces enzyme activity
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
additional information
?
-
-
key enzyme in NAD biosynthesis from tryptophan
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
important enzyme regulating tryptophan-niacin metabolism
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate-6-semialdehyde + CO2
tryptophan-niacine pathway
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
-
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
2-aminomuconate semialdehyde + CO2
-
key enzyme in the regulation of the tryptophan-nicotinamide adenine dinucleotide pathway
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
suppression of the enzyme activity by linoleic acid in relation to its induction by glucocorticoids and dietary protein
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
expression level of EC 4.1.1.45 might by modulated by linoleic acid or its metabolites
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
effect of dietary protein and soybean oil which contains about 85% unsaturated fatty acids
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
directly related to the concentration of blood muconate
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
key enzyme of niacin synthesis from Trp
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
effect of various dietary fatty acids on enzyme activity
-
-
?
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
?
-
40% casein diet, nicotinic acid-free, significantly reduces enzyme activity
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Shibata, K.
Tryptophan-niacin metabolism in alloxan diabetic rats and partial prevention of alloxan diabetes by nicotinamide
Agric. Biol. Chem.
51
811-816
1987
Rattus norvegicus
-
brenda
Shibata, K.; Hayakawa, T.; Iwai, K.
Comparison of the enzyme activities in the tryptophan-NAD pathway between the Wistar and Sprague Dawley strains of rats
Agric. Biol. Chem.
50
1643-1644
1986
Rattus norvegicus
-
brenda
Shibata, K.; Murata, K.
Comparison of the activity of the tryptophan-NAD pathway between rats fed a fat-free diet and a fat diet
Agric. Biol. Chem.
49
2899-2904
1985
Rattus norvegicus
-
brenda
Egashira, Y.; Tanabe, A.; Ohta, T.; Sanada, H.
Dietary linoleic acid alters alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of niacin synthesis from tryptophan, in the process of protein expression in rat liver
J. Nutr. Sci. Vitaminol.
44
129-136
1998
Rattus norvegicus
brenda
Sanada, H.; Takahashi, T.; Miyazaki, M.
Effects of dietary fat and protein on the activity of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase and the urinary excretion of niacin metabolites in rats
J. Nutr. Sci. Vitaminol.
37
39-51
1991
Rattus norvegicus
brenda
Egashira, Y.; Ogawara, R.; Ohta, T.; Sanada, H.
Suppression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) activity by linoleic acid in relation to its induction by glucocorticoids and dietary protein
Biosci. Biotechnol. Biochem.
58
339-343
1994
Rattus norvegicus
-
brenda
Egashira, Y.; Yamamiya, Y.; Sanada, H.
Effects of various dietary fatty acids on alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity in rat liver
Biosci. Biotechnol. Biochem.
56
2015-2019
1992
Rattus norvegicus
-
brenda
Fukuoka, S.; Tanabe, A.; Egashira, Y.; Sanada, H.; Shin, M.; Shibata, K.
Identification of cDNAs encoding alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSDase)
Adv. Exp. Med. Biol.
467
615-618
1999
Caenorhabditis elegans, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
brenda
Tanabe, A.; Egashira, Y.; Fukuoka, S.; Shibata, K.; Sanada, H.
Purification and molecular cloning of rat 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
Biochem. J.
361
567-575
2002
Rattus norvegicus (Q8R5M5), Rattus norvegicus Wistar (Q8R5M5)
brenda
Fukuoka, S.; Ishiguro, K.; Yanagihara, K.; Tanabe, A.; Egashira, Y.; Sanada, H.; Shibata, K.
Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis"
J. Biol. Chem.
277
35162-35167
2002
Homo sapiens (Q8TDX5), Homo sapiens, Mus musculus (Q8R519), Mus musculus ICR (Q8R519), Rattus norvegicus (Q8R5M5), Sus scrofa
brenda
Egashira, Y.; Murotani, G.; Tanabe, A.; Saito, K.; Uehara, K.; Morise, A.; Sato, M.; Sanada, H.
Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression
Biochim. Biophys. Acta
1686
118-124
2004
Rattus norvegicus
brenda
Fukuwatari, T.; Ohsaki, S.; Fukuoka, S.; Sasaki, R.; Shibata, K.
Phthalate esters enhance quinolinate production by inhibiting alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of the tryptophan pathway
Toxicol. Sci.
81
302-308
2004
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Sasaki, N.; Egashira, Y.; Sanada, H.
Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalpha
Eur. J. Nutr.
47
80-86
2008
Rattus norvegicus
brenda
Sasaki, N.; Egashira, Y.; Sanada, H.
Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats
Eur. J. Nutr.
48
145-153
2009
Rattus norvegicus
brenda
Matsuda, H.; Gomi, R.T.; Hirai, S.; Egashira, Y.
Effect of dietary phytol on the expression of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism, in rats
Biosci. Biotechnol. Biochem.
77
1416-1419
2013
Rattus norvegicus
brenda
Matsuda, H.; Sato, M.; Yakushiji, M.; Koshiguchi, M.; Hirai, S.; Egashira, Y.
Regulation of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2
Eur. J. Nutr.
53
469-477
2014
Rattus norvegicus (Q8R5M5)
brenda