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Information on EC 4.1.1.39 - ribulose-bisphosphate carboxylase and Organism(s) Arabidopsis thaliana and UniProt Accession O03042
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4.1.1.39 ribulose-bisphosphate carboxylaseIUBMB Comments
Will utilize O2 instead of CO2, forming 3-phospho-D-glycerate and 2-phosphoglycolate.
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Word Map
- 4.1.1.39
- co2
- chloroplast
- chlorophyll
-
stomatal
- plastid
- mesophyll
- activase
- photosystems
- spinach
- seedling
- dioxide
- thylakoids
- phosphoenolpyruvate
- wheat
-
photorespiration
-
atmospheric
- maize
-
acclimation
- chlamydomonas
- cyanobacteria
- drought
- reinhardtii
-
autotroph
-
photochemical
- anhydrase
-
photorespiratory
-
calvin
-
climate
-
light-harvesting
-
transpiration
-
nuclear-encoded
- rubrum
- aestivum
- triticum
- rhodospirillum
- 3-phosphoglycerate
-
canopy
- synechococcus
- phosphoribulokinase
-
photoautotrophic
-
photochemistry
- analysis
-
crassulacean
- molecular biology
- lhcii
- biotechnology
-
photoinhibition
-
non-photochemical
-
carbamylation
- carboxylases
-
nadp-malic
- dikinase
-
oxygen-evolving
- biofuel production
- agriculture
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
rubisco, ribulose-1,5-bisphosphate carboxylase/oxygenase, ribulose-1,5-bisphosphate carboxylase, rubpcase, ribulose bisphosphate carboxylase, ribulose 1,5-bisphosphate carboxylase/oxygenase, ribulose 1,5-bisphosphate carboxylase, ribulose bisphosphate carboxylase/oxygenase, rubp carboxylase, rubisco small subunit, 
more
topSYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
Carboxydismutase
-
-
-
-
D-Ribulose 1,5-diphosphate carboxylase
-
-
-
-
D-Ribulose-1,5-bisphosphate carboxylase
-
-
-
-
Diphosphoribulose carboxylase
-
-
-
-
LESS17
-
-
-
-
PSS15
-
-
-
-
PSSU1
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase-oxygenase
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase/oxygenase
-
-
-
-
Ribulose 1,5-diphosphate carboxylase
-
-
-
-
Ribulose 1,5-diphosphate carboxylase/oxygenase
-
-
-
-
Ribulose bisphosphate carboxylase-oxygenase
-
-
-
-
Ribulose diphosphate carboxylase
-
-
-
-
Ribulose diphosphate carboxylase/oxygenase
-
-
-
-
ribulose-1,5-bisphosphate carboxylase/oxygenase
-
-
Rubisco
RuBP carboxylase
-
-
-
-
Water stress responsive proteins 1, 2 and 14
-
-
-
-
Rubisco
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
carboxylation
-
-
-
-
oxygenation
-
-
-
-
PATHWAY SOURCE
PATHWAYS
BRENDA
KEGG
-
-, -, -
SYSTEMATIC NAME
IUBMB Comments
3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming)
Will utilize O2 instead of CO2, forming 3-phospho-D-glycerate and 2-phosphoglycolate.
CAS REGISTRY NUMBER
COMMENTARY
9027-23-0
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate + H+
-
-
-
-
?
D-ribulose 1,5-bisphosphate + O2
3-phospho-D-glycerate + 2-phosphoglycolate
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation, as the entry point of CO2 into the biosphere, enzyme is central to life on earth
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation, CO2 fixing enzyme that enables most forms of photo-and chemoautotrophic life
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
key enzyme responsible for photosynthetic carbon assimilation and photorespiratory carbon oxidation
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate + H+
-
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation, as the entry point of CO2 into the biosphere, enzyme is central to life on earth
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation, CO2 fixing enzyme that enables most forms of photo-and chemoautotrophic life
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
key enzyme responsible for photosynthetic carbon assimilation and photorespiratory carbon oxidation
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
4.1
D-ribulose 1,5-bisphosphate
-
in 100 mM Bicine-NaOH pH 8.0, 20 mM MgCl2, at 25°C
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
417
D-ribulose 1,5-bisphosphate
-
in 100 mM Bicine-NaOH pH 8.0, 20 mM MgCl2, at 25°C
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). RBL_ARATH
479
0
52955
Swiss-Prot
other Location (Reliability: 2)
PDB
SCOP
CATH
UNIPROT
ORGANISM
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
ammonium sulfate precipitation, rate zonal centrifugation using sucrose gradients or Sephacryl S-300 gel filtration (alternatively), and Q Sepharose column chromatography
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
the rbcS cDNA is expressed in Chlamydomonas reinhardtii rbcS deletion mutant T60-3 by fusing it to a Chlamydomonas rbcS transit peptide sequence engineered to contain rbcS introns
-
APPLICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
analysis
1 pg of plant mRNA, ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, is used to determine the efficiency of RT-PCR in general, and as a external reference gene for normalization of gene expression
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Spreitzer, R.J.; Salvucci, M.E.
Rubisco: Structure, regulatory interactions, and possibilities for a better enzyme
Annu. Rev. Plant Biol.
53
449-475
2002
Cupriavidus necator, Anabaena sp., Trichormus variabilis, Synechococcus elongatus PCC 7942 = FACHB-805, Arabidopsis thaliana, Chlamydomonas reinhardtii, Chlorobaculum tepidum, Cylindrotheca sp., Flaveria bidentis, Galdieria partita, Helianthus annuus, Solanum lycopersicum, Nicotiana tabacum, Oryza sativa, Thermococcus kodakarensis, Rhodospirillum rubrum, Spinacia oleracea, Synechococcus sp., Zea mays, Amphidinium carterae, Anabaena sp. CA
John Andrews, T.; Whitney, S.M.
Manipulating ribulose bisphosphate carboxylase/oxygenase in the chloroplasts of higher plants
Arch. Biochem. Biophys.
414
159-169
2003
Synechocystis sp., Arabidopsis thaliana, Flaveria bidentis, Galdieria sulphuraria, Nicotiana tabacum, Oryza sativa, Phaeodactylum tricornutum, Rhodospirillum rubrum, Griffithsia monilis
Parry, M.A.; Andralojc, P.J.; Mitchell, R.A.; Madgwick, P.J.; Keys, A.J.
Manipulation of Rubisco: the amount, activity, function and regulation
J. Exp. Bot.
54
1321-1333
2003
Allochromatium vinosum, Arabidopsis thaliana, Avena sativa, Chlamydomonas reinhardtii, Cylindrotheca sp., Flaveria bidentis, Galdieria partita, Galdieria sulphuraria, Glycine max, Helianthus annuus, Hordeum vulgare, Solanum lycopersicum, Nicotiana tabacum, Olisthodiscus luteus, Oryza sativa, Petunia sp., Phaeodactylum tricornutum, Pisum sativum, Rhodobacter capsulatus, Cereibacter sphaeroides, Rhodospirillum rubrum, Spinacia oleracea, Triticum aestivum, Zea mays, Cylindrotheca sp. N1
Sorensen, B.; Jones, J.F.; Vernon, S.D.; Rajeevan, M.S.
Transcriptional control of complement activation in an exercise model of chronic fatigue syndrome
Mol. Med.
15
34-42
2009
Arabidopsis thaliana (O03042)
Genkov, T.; Meyer, M.; Griffiths, H.; Spreitzer, R.J.
Functional hybrid Rubisco enzymes with plant small subunits and algal large subunits: engineered rbcS cDNA for expression in Chlamydomonas
J. Biol. Chem.
285
19833-19841
2010
Arabidopsis thaliana, Chlamydomonas reinhardtii, Helianthus annuus, Spinacia oleracea
Carmo-Silva, A.E.; Barta, C.; Salvucci, M.E.
Isolation of ribulose-1,5-bisphosphate carboxylase/oxygenase from leaves
Methods Mol. Biol.
684
339-347
2011
Arabidopsis thaliana, Chlamydomonas sp., Nicotiana tabacum, Spinacia oleracea, Xanthium sp.
Walker, B.; Ariza, L.S.; Kaines, S.; Badger, M.R.; Cousins, A.B.
Temperature response of in vivo Rubisco kinetics and mesophyll conductance in Arabidopsis thaliana: comparisons to Nicotiana tabacum
Plant Cell Environ.
36
2108-2119
2013
Arabidopsis thaliana, Nicotiana tabacum
Galmes, J.; Kapralov, M.V.; Andralojc, P.J.; Conesa, M.A.; Keys, A.J.; Parry, M.A.; Flexas, J.
Expanding knowledge of the Rubisco kinetics variability in plant species: environmental and evolutionary trends
Plant Cell Environ.
37
1989-2001
2014
Arabidopsis thaliana, Atrichum undulatum, Dactylis glomerata, Drosera capensis, Marchantia polymorpha, Metasequoia glyptostroboides, Pteridium aquilinum, Triticum aestivum, Trachycarpus fortunei, Ceratophyllum demersum, Platycerium superbum, Cycas panzhihuaensis, Nymphaea alba, Agave victoriae-reginae, Carpobrotus edulis, Echeveria elegans, Drosera venusta, Sarracenia flava, Eucalyptus moorei, Eucalyptus neglecta, Iris douglasiana, Crithmum maritimum, Limonium latibracteatum, Limonium stenophyllum, Limonium virgatum, Pallenis maritima, Sideritis cretica subsp. spicata, Teucrium heterophyllum
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