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Information on EC 4.1.1.17 - ornithine decarboxylase and Organism(s) Haemonchus contortus and UniProt Accession O76203

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.17 ornithine decarboxylase
IUBMB Comments
A pyridoxal-phosphate protein.
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Select one or more organisms in this record: ?
This record set is specific for:
Haemonchus contortus
UNIPROT: O76203
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Word Map
The taxonomic range for the selected organisms is: Haemonchus contortus
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
Synonyms
odc, ornithine decarboxylase, ldodc, lysine/ornithine decarboxylase, s-adenosylmethionine decarboxylase/ornithine decarboxylase, ldc/odc, odc-paralogue, xodc2, adometdc/odc, ddodc, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
bODC
-
-
-
-
Decarboxylase, ornithine
-
-
-
-
ODC
-
-
-
-
ODC-paralogue
-
-
-
-
XODC1
-
-
-
-
XODC2
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
decarboxylation
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
L-ornithine carboxy-lyase (putrescine-forming)
A pyridoxal-phosphate protein.
CAS REGISTRY NUMBER
COMMENTARY hide
9024-60-6
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-Orn
?
show the reaction diagram
primary regulatory enzyme in polyamine biosynthesis
-
-
?
L-Orn
Putrescine + CO2
show the reaction diagram
-
-
-
?
L-Orn
Putrescine + CO2
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-Orn
?
show the reaction diagram
primary regulatory enzyme in polyamine biosynthesis
-
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
Uniprot
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
O76203_HAECO
422
0
46739
TrEMBL
other Location (Reliability: 2)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli and Saccharomyces cerevisiae
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schaeffer, J.M.; Donatelli, M.R.
Characterization of a high affinity membrane-associated ornithine decarboxylase from the free-living nematode Caenorhabditis elegans
Biochem. J.
270
599-604
1990
Caenorhabditis elegans, Haemonchus contortus
Manually annotated by BRENDA team
Klein, R.D.; Favreau, M.A.; Alexander-Bowman, S.J.; Nulf, S.C.; Vanover, L.; Winterrowd, C.A.; Yarlett, N.; Martinez, M.; Keithly, J.S.; Zantello, M.R.; Thomas, E.M.; Geary, T.G.
Haemonchus contortus: cloning and functional expression of a cDNA encoding ornithine decarboxylase and development of a screen for inhibitors
Exp. Parasitol.
87
171-184
1997
Haemonchus contortus (O76203), Haemonchus contortus
Manually annotated by BRENDA team