Information on EC 3.8.1.1 - alkylhalidase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

EC NUMBER
COMMENTARY hide
3.8.1.1
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RECOMMENDED NAME
GeneOntology No.
alkylhalidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
bromochloromethane + H2O = formaldehyde + bromide + chloride
show the reaction diagram
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-
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-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C-halide hydrolysis
hydrolysis of C-halide
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SYSTEMATIC NAME
IUBMB Comments
alkyl-halide halidohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
9025-22-3
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain DSM5908, gene bhaA in the balhimycin biosynthesis gene cluster
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Manually annotated by BRENDA team
strain DSM5908, gene bhaA in the balhimycin biosynthesis gene cluster
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
BrH2CCH2Br + 2 H2O
OHCCHO + 6 H+ + 2 Br-
show the reaction diagram
-
-
-
-
?
CH2Br-CH2Cl + H2O
?
show the reaction diagram
-
-
-
-
?
CH2Br2 + H2O
HCHO + 2 H+ + 2 Br-
show the reaction diagram
-
-
-
-
?
CH2BrCl + H2O
HCHO + H+ + Br- + Cl-
show the reaction diagram
-
-
-
-
?
CH2Cl2 + H2O
HCHO + H+ + Cl-
show the reaction diagram
-
-
-
-
?
CH3Br + H2O
?
show the reaction diagram
-
-
-
-
?
CHCl3 + H2O
?
show the reaction diagram
-
-
-
-
?
ClH2CCH2Cl + 2 H2O
OHCCHO + 6 H+ + 2 Cl-
show the reaction diagram
-
-
-
-
?
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
BrH2CCH2Br + 2 H2O
OHCCHO + 6 H+ + 2 Br-
show the reaction diagram
-
-
-
-
?
CH2Br-CH2Cl + H2O
?
show the reaction diagram
-
-
-
-
?
CH2Br2 + H2O
HCHO + 2 H+ + 2 Br-
show the reaction diagram
-
-
-
-
?
CH2BrCl + H2O
HCHO + H+ + Br- + Cl-
show the reaction diagram
-
-
-
-
?
CH2Cl2 + H2O
HCHO + H+ + Cl-
show the reaction diagram
-
-
-
-
?
CH3Br + H2O
?
show the reaction diagram
-
-
-
-
?
CHCl3 + H2O
?
show the reaction diagram
-
-
-
-
?
ClH2CCH2Cl + 2 H2O
OHCCHO + 6 H+ + 2 Cl-
show the reaction diagram
-
-
-
-
?
additional information
?
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Fe2+
-
dependent on
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
cysteine
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glutathione
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
PDB
SCOP
CATH
ORGANISM
UNIPROT
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partially by ammonium sulfate fractionation
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
DNA sequence determination, genomic organiszation in the balhimycin biosynthesis gene cluster, expression of mutant enzymes in Amycolatopsis mediterranei, subcloning in Escherichia coli
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ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis