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GTP + H2O
GDP + phosphate
ATP + H2O
ADP + phosphate
-
dynamin also has ATPase activity
-
-
?
GTP + H2O
GDP + phosphate
additional information
?
-
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
-
ir
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
regulates late events in clathrin-coated vescicle formation, GTP hydrolysis is required for vesicle detachment, a concerted conformational change resulting from coordinated GTP hydrolysis by the dynamin oligomer might by sufficient to generate force
-
?
GTP + H2O
GDP + phosphate
-
dynamin 2 can act as a signal transducing GTPase affecting transcriptional regulation
-
?
GTP + H2O
GDP + phosphate
-
enzyme is involved in endocytosis
-
?
GTP + H2O
GDP + phosphate
-
enzyme is involved in endocytosis
-
?
GTP + H2O
GDP + phosphate
-
enzyme is involved in endocytosis
-
?
GTP + H2O
GDP + phosphate
-
dynamin I phosphorylation by protein kinase C and dephosphorylation by calcineurin serve as molecular switches to control nerve terminal vesicle recycling
-
?
GTP + H2O
GDP + phosphate
-
through its ability to oligomerize, dynamin appears to form a structural collar around the neck of caveolae that hydrolyzes GTP to mediate internalization via the fission of caveolae from the plasma membrane to form free transport vesicles
-
?
GTP + H2O
GDP + phosphate
-
dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity
-
-
?
GTP + H2O
GDP + phosphate
-
GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission
-
-
?
GTP + H2O
GDP + phosphate
-
the role of dynamin in the assembly and function of podosomes and invadopodia
-
-
?
additional information
?
-
-
Arp2/3-mediated actin polymerization regulates the accessibility of cortactin to dynamin 2 and implies a novel mechanism by which cortactin and dynamin drive the fission of clathrin-coated pits in an actin polymerization dependent manner
-
-
?
additional information
?
-
dynamin 2 is specifically required for clathrin-mediated endocytosis in fibroblastoid cells, p75 export from the Golgi, and PDGF-stimulated macropinocytosis and cytokinesis, but not for other endocytic pathways, clathrin-mediated endocytosis and p75 exocytosis are efficiently rescued by reintroduction of dynamin 2, but not dynamin 1, suggesting that these two isoforms function differentially in vesicular trafficking in nonneuronal cells. Both isoforms rescue macropinocytosis and cytokinesis, suggesting that dynamin function in these processes may be mechanistically distinct from its role in clathrin-mediated endocytosis. Although all four dynamin 2 splice variants can equally restore clathrin-mediated endocytosis, dynamin 2ba and dynamin 2bb are more effective at restoring p75 exocytosis.
-
-
?
additional information
?
-
dynamin 2 is specifically required for clathrin-mediated endocytosis in fibroblastoid cells, p75 export from the Golgi, and PDGF-stimulated macropinocytosis and cytokinesis, but not for other endocytic pathways, clathrin-mediated endocytosis and p75 exocytosis are efficiently rescued by reintroduction of dynamin 2, but not dynamin 1, suggesting that these two isoforms function differentially in vesicular trafficking in nonneuronal cells. Both isoforms rescue macropinocytosis and cytokinesis, suggesting that dynamin function in these processes may be mechanistically distinct from its role in clathrin-mediated endocytosis. Although all four dynamin 2 splice variants can equally restore clathrin-mediated endocytosis, dynamin 2ba and dynamin 2bb are more effective at restoring p75 exocytosis.
-
-
?
additional information
?
-
dynamin 2 is specifically required for clathrin-mediated endocytosis in fibroblastoid cells, p75 export from the Golgi, and PDGF-stimulated macropinocytosis and cytokinesis, but not for other endocytic pathways, clathrin-mediated endocytosis and p75 exocytosis are efficiently rescued by reintroduction of dynamin 2, but not dynamin 1, suggesting that these two isoforms function differentially in vesicular trafficking in nonneuronal cells. Both isoforms rescue macropinocytosis and cytokinesis, suggesting that dynamin function in these processes may be mechanistically distinct from its role in clathrin-mediated endocytosis. Although all four dynamin 2 splice variants can equally restore clathrin-mediated endocytosis, dynamin 2ba and dynamin 2bb are more effective at restoring p75 exocytosis.
-
-
?
additional information
?
-
-
dynamin is a binding partner of histamine H2 receptor, agonist-induced internalization of histamine H2 receptor and activation of extracellular signal-regulated kinases are dynamin-dependent. Dynamin is not involved in adenylate cyclase activation or desensitisation.
-
-
?
additional information
?
-
LOX-1 internalisation is regulated by dynamin-2
-
-
?
additional information
?
-
-
the PH domain binds acidic phospholipids in the cytosolic leaflet of the plasma membrane, and phosphatidylinositol-4,5-bisphosphate in particular, via a positively charged surface at the foot of the dynamin hairpin. The membrane interaction is strengthened by charge-dependent association with other negatively charged phospholipids and by avidity afforded by dynamin polymerization
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
additional information
?
-
GTP + H2O
GDP + phosphate
-
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
-
ir
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
-
-
?
GTP + H2O
GDP + phosphate
-
regulates late events in clathrin-coated vescicle formation, GTP hydrolysis is required for vesicle detachment, a concerted conformational change resulting from coordinated GTP hydrolysis by the dynamin oligomer might by sufficient to generate force
-
?
GTP + H2O
GDP + phosphate
-
dynamin 2 can act as a signal transducing GTPase affecting transcriptional regulation
-
?
GTP + H2O
GDP + phosphate
-
enzyme is involved in endocytosis
-
?
GTP + H2O
GDP + phosphate
-
enzyme is involved in endocytosis
-
?
GTP + H2O
GDP + phosphate
-
enzyme is involved in endocytosis
-
?
GTP + H2O
GDP + phosphate
-
dynamin I phosphorylation by protein kinase C and dephosphorylation by calcineurin serve as molecular switches to control nerve terminal vesicle recycling
-
?
GTP + H2O
GDP + phosphate
-
through its ability to oligomerize, dynamin appears to form a structural collar around the neck of caveolae that hydrolyzes GTP to mediate internalization via the fission of caveolae from the plasma membrane to form free transport vesicles
-
?
GTP + H2O
GDP + phosphate
-
dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity
-
-
?
GTP + H2O
GDP + phosphate
-
GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission
-
-
?
GTP + H2O
GDP + phosphate
-
the role of dynamin in the assembly and function of podosomes and invadopodia
-
-
?
additional information
?
-
-
Arp2/3-mediated actin polymerization regulates the accessibility of cortactin to dynamin 2 and implies a novel mechanism by which cortactin and dynamin drive the fission of clathrin-coated pits in an actin polymerization dependent manner
-
-
?
additional information
?
-
dynamin 2 is specifically required for clathrin-mediated endocytosis in fibroblastoid cells, p75 export from the Golgi, and PDGF-stimulated macropinocytosis and cytokinesis, but not for other endocytic pathways, clathrin-mediated endocytosis and p75 exocytosis are efficiently rescued by reintroduction of dynamin 2, but not dynamin 1, suggesting that these two isoforms function differentially in vesicular trafficking in nonneuronal cells. Both isoforms rescue macropinocytosis and cytokinesis, suggesting that dynamin function in these processes may be mechanistically distinct from its role in clathrin-mediated endocytosis. Although all four dynamin 2 splice variants can equally restore clathrin-mediated endocytosis, dynamin 2ba and dynamin 2bb are more effective at restoring p75 exocytosis.
-
-
?
additional information
?
-
dynamin 2 is specifically required for clathrin-mediated endocytosis in fibroblastoid cells, p75 export from the Golgi, and PDGF-stimulated macropinocytosis and cytokinesis, but not for other endocytic pathways, clathrin-mediated endocytosis and p75 exocytosis are efficiently rescued by reintroduction of dynamin 2, but not dynamin 1, suggesting that these two isoforms function differentially in vesicular trafficking in nonneuronal cells. Both isoforms rescue macropinocytosis and cytokinesis, suggesting that dynamin function in these processes may be mechanistically distinct from its role in clathrin-mediated endocytosis. Although all four dynamin 2 splice variants can equally restore clathrin-mediated endocytosis, dynamin 2ba and dynamin 2bb are more effective at restoring p75 exocytosis.
-
-
?
additional information
?
-
dynamin 2 is specifically required for clathrin-mediated endocytosis in fibroblastoid cells, p75 export from the Golgi, and PDGF-stimulated macropinocytosis and cytokinesis, but not for other endocytic pathways, clathrin-mediated endocytosis and p75 exocytosis are efficiently rescued by reintroduction of dynamin 2, but not dynamin 1, suggesting that these two isoforms function differentially in vesicular trafficking in nonneuronal cells. Both isoforms rescue macropinocytosis and cytokinesis, suggesting that dynamin function in these processes may be mechanistically distinct from its role in clathrin-mediated endocytosis. Although all four dynamin 2 splice variants can equally restore clathrin-mediated endocytosis, dynamin 2ba and dynamin 2bb are more effective at restoring p75 exocytosis.
-
-
?
additional information
?
-
-
dynamin is a binding partner of histamine H2 receptor, agonist-induced internalization of histamine H2 receptor and activation of extracellular signal-regulated kinases are dynamin-dependent. Dynamin is not involved in adenylate cyclase activation or desensitisation.
-
-
?
additional information
?
-
LOX-1 internalisation is regulated by dynamin-2
-
-
?
additional information
?
-
-
the PH domain binds acidic phospholipids in the cytosolic leaflet of the plasma membrane, and phosphatidylinositol-4,5-bisphosphate in particular, via a positively charged surface at the foot of the dynamin hairpin. The membrane interaction is strengthened by charge-dependent association with other negatively charged phospholipids and by avidity afforded by dynamin polymerization
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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cardiolipin
stimulates Drp1, synergistically with mitochondrial fission factor
endogenouse rat brain vesicles
-
cooperative interactions between dynamin molecules are responsible for the apparent activation of GTPase observed
-
lipid tubule
-
stimulate GTPase activity
-
Mff-proteoliposome
lipid-stimulated GTPase activity
-
mitochondrial fission factor
Mff, stimulates Drp1 independently of, but synergistically with cardiolipin
-
phosphatidylglycerol
-
stimulates
phosphatidylinositol
-
stimulates
phosphatidylserine
-
stimulates
phospholipase D
-
PLD function as a GTPase activating protein, GAP, through its phox homology domain, PX, which directly activates the GTPase domain of dynamin
-
Arc/Arg3.1
enhances dynamin polymerization and GTPase activity. The activity-regulated cytoskeleton-associated protein, Arc, is an immediate-early gene product implicated in various forms of synaptic plasticity. Arc promotes endocytosis of AMPA type glutamate receptors and regulates cytoskeletal assembly in neuronal dendrites. Bacterially-expressed His6-Arc facilitates the polymerization of Dyn2 and stimulates its GTPase activity under physiologic conditions (37°C and 100 mM NaCl). At lower ionic strength Arc also stabilizes preformed Dyn2 polymers against GTP-dependent disassembly, thereby prolonging assembly-dependent GTP hydrolysis catalyzed by Dyn2. Arc also increases the GTPase activity of Dyn3, an isoform of implicated in dendrite remodeling, but does not affect the activity of Dyn1, a neuron-specific isoform involved in synaptic vesicle recycling. Analysis of recombinant full-length mouse Arc and of His6-tagged fragments, including Arc-N (residues 1-227), Arc-C (residues 228-396), and Arc-(DELTA195-214). While residues 195-214 may contribute to dynamin binding, additional binding determinants are likely to be present in the N-terminal portion of Arc. Arc stimulates the assembly-dependent GTPase activity of isozymes Dyn2 and Dyn3. The effect of Arc on GTPase activity of dynamin mirrors its effect on dynamin assembly as measured by turbidity
-
Arc/Arg3.1
enhances dynamin polymerization and GTPase activity. The activity-regulated cytoskeleton-associated protein, Arc, is an immediate-early gene product implicated in various forms of synaptic plasticity. Arc promotes endocytosis of AMPA type glutamate receptors and regulates cytoskeletal assembly in neuronal dendrites. Bacterially-expressed His6-Arc increases the GTPase activity of Dyn3, an isoform of implicated in dendrite remodeling. Analysis of recombinant full-length mouse Arc and of His6-tagged fragments, including Arc-N (residues 1-227), Arc-C (residues 228-396), and Arc-(DELTA195-214). Arc stimulates the assembly-dependent GTPase activity of isozymes Dyn2 and Dyn3. The effect of Arc on GTPase activity of dynamin mirrors its effect on dynamin assembly as measured by turbidity
-
microtubules
-
stimulates
-
microtubules
-
cooperative interactions between dynamin molecules are responsible for the apparent activation of GTPase observed
-
microtubules
-
accelerates GTPase activity up to 150fold, about 4fold activation of ATPase activity
-
Phospholipid
-
acidic phospholipids, cooperative interactions between dynamin molecules are responsible for the apparent activation of GTPase observed
Phospholipid
-
mixed-lineage kinase 2-SH2 domain binds dynamin and greatly enhances activation of GTPase by phospholipid
SH3 domains
-
stimulates
-
SH3 domains
-
stimulation by several recombinant SH3 domains, binding through proline-rich sequence motifs
-
additional information
activity-regulated cytoskeleton-associated protein, Arc (Arc/Arg3.1) is an immediate-early gene product implicated in various forms of synaptic plasticity. Arc promotes endocytosis of AMPA type glutamate receptors and regulates cytoskeletal assembly in neuronal dendrites. Bacterially-expressed His6-Arc does not affect the activity of Dyn1, a neuron-specific isoform involved in synaptic vesicle recycling, in contrast to the other Dyn isozymes, Arc stimulates the assembly-dependent GTPase activity of Dyn2 and Dyn3. Analysis of recombinant full-length mouse Arc and of His6-tagged fragments, including Arc-N (residues 1-227), Arc-C (residues 228-396), and Arc-(DELTA195-214)
-
additional information
activity-regulated cytoskeleton-associated protein, Arc (Arc/Arg3.1) is an immediate-early gene product implicated in various forms of synaptic plasticity. Arc promotes endocytosis of AMPA type glutamate receptors and regulates cytoskeletal assembly in neuronal dendrites. Bacterially-expressed His6-Arc does not affect the activity of Dyn1, a neuron-specific isoform involved in synaptic vesicle recycling, in contrast to the other Dyn isozymes, Arc stimulates the assembly-dependent GTPase activity of Dyn2 and Dyn3. Analysis of recombinant full-length mouse Arc and of His6-tagged fragments, including Arc-N (residues 1-227), Arc-C (residues 228-396), and Arc-(DELTA195-214)
-
additional information
activity-regulated cytoskeleton-associated protein, Arc (Arc/Arg3.1) is an immediate-early gene product implicated in various forms of synaptic plasticity. Arc promotes endocytosis of AMPA type glutamate receptors and regulates cytoskeletal assembly in neuronal dendrites. Bacterially-expressed His6-Arc does not affect the activity of Dyn1, a neuron-specific isoform involved in synaptic vesicle recycling, in contrast to the other Dyn isozymes, Arc stimulates the assembly-dependent GTPase activity of Dyn2 and Dyn3. Analysis of recombinant full-length mouse Arc and of His6-tagged fragments, including Arc-N (residues 1-227), Arc-C (residues 228-396), and Arc-(DELTA195-214)
-
additional information
-
dynamin I and II are stimulated by self-assembly, dynamin II has a greater propensity for self-assembly than neuronal dynamin I
-
additional information
-
the GAP function of PLD1-PX stimulates the GTPase activity of dynamin by increasing dynamin self-assembly
-
additional information
-
robust stimulation of dynamin's GTPase activity upon polymerization
-
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Liu, J.P.; Sim, A.T.R.; Robinson, P.J.
Calcineurin inhibition of dynamin I GTPase activity coupled to nerve terminal depolarization
Science
265
970-973
1994
Rattus norvegicus
brenda
Rasmussen, R.K.; Rusak, J.; Price, G.; Robinson, P.J.; Simpson, R.J.; Dorow, D.S.
Mixed-lineage kinase 2-SH2 domain binds dynamin and greatly enhances activation of GTPase by phospholipid
Biochem. J.
335
119-124
1998
Ovis aries, Homo sapiens, Rattus norvegicus
brenda
Oh, P.; McIntosh, D.P.; Schnitzer, J.E.
Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium
J. Cell Biol.
141
101-114
1998
Rattus norvegicus
brenda
Tuma, P.L.; Stachniak, M.C.; Collins, C.A.
Activation of dynamin GTPase by acidic phospholipids and endogenous rat brain vesicles
J. Biol. Chem.
268
17240-17246
1993
Rattus norvegicus
brenda
Tuma, P.L.; Collins, C.A.
Activation of dynamin GTPase is a result of positive cooperativity
J. Biol. Chem.
269
30842-30847
1994
Rattus norvegicus
brenda
Liu, J.P.; Zhang, Q.X.; Baldwin, G.; Robinson, P.J.
Calcium binds dynamin I and inhibits its GTPase activity
J. Neurochem.
66
2074-2081
1996
Rattus norvegicus
brenda
Fish, K.N.; Schmid, S.L.; Damke, H.
Evidence that dynamin-2 functions as a signal-transducing GTPase
J. Cell Biol.
150
145-154
2000
Homo sapiens, Rattus norvegicus
brenda
Gout, I.; Dhand, R.; Hiles, I.D.; Fry, M.J.; Panayotou, G; Das, P.; Truong, O.; Totty, N.F.; Hsuan, J.; Booker, G.W.; Campbell, I.D.; Waterfield, M.D.
: The GTPase dynamin binds to and is activated by a subset of SH3 domains
Cell
75
25-36
1993
Rattus norvegicus
brenda
Maeda, K.; Nakata, T.; Noda, Y.; Sato-Yoshitake, R.; Hirokawa, N.
Interaction of dynamin with microtubules: its structure and GTPase activity investigated by using highly purified dynamin
Mol. Biol. Cell
3
1181-1194
1992
Rattus norvegicus
brenda
Warnock, D.E.; Schmid, S.L.
Dynamin GTPase, a force-generating molecular switch
Bioessays
18
885-893
1996
Drosophila sp. (in: flies), Homo sapiens, Rattus norvegicus
brenda
Warnock, D.E.; Baba, T.; Schmidt, S.L.
Ubiquitously expressed dynamin-II has a higher intrinsic GTPase activity and a greater propensity for self-assembly than neuronal dynamin-I
Mol. Biol. Cell
8
2553-2562
1997
Rattus norvegicus
brenda
Jiang, S.; Avraham, H.K.; Kim, T.A.; Rogers, R.A.; Avraham, S.
Receptor-type PTP-NP inhibition of dynamin-1 GTPase activity is associated with neuronal depolarization
Cell. Signal.
18
1439-1446
2006
Rattus norvegicus
brenda
McNiven, M.A.; Baldassarre, M.; Buccione, R.
The role of dynamin in the assembly and function of podosomes and invadopodia
Front. Biosci.
9
1944-1953
2004
Rattus norvegicus
brenda
Zanner, R.; Gratzl, M.; Prinz, C.
Expression of the endocytic proteins dynamin and amphiphysin in rat gastric enterochromaffin-like cells
J. Cell Sci.
117
2369-2376
2004
Rattus norvegicus (P21575), Rattus norvegicus (P39052)
brenda
Zhu, J.; Zhou, K.; Hao, J.J.; Liu, J.; Smith, N.; Zhan, X.
Regulation of cortactin/dynamin interaction by actin polymerization during the fission of clathrin-coated pits
J. Cell Sci.
118
807-817
2005
Rattus norvegicus
brenda
Bruzzaniti, A.; Neff, L.; Sanjay, A.; Horne, W.C.; De Camilli, P.; Baron, R.
Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity
Mol. Biol. Cell
16
3301-3313
2005
Rattus norvegicus
brenda
Roux, A.; Uyhazi, K.; Frost, A.; De Camilli, P.
GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission
Nature
441
528-531
2006
Rattus norvegicus
brenda
Reubold, T.F.; Eschenburg, S.; Becker, A.; Leonard, M.; Schmid, S.L.; Vallee, R.B.; Kull, F.J.; Manstein, D.J.
Crystal structure of the GTPase domain of rat dynamin 1
Proc. Natl. Acad. Sci. USA
102
13093-13098
2005
Rattus norvegicus
brenda
Lee, C.S.; Kim, I.S.; Park, J.B.; Lee, M.N.; Lee, H.Y.; Suh, P.G.; Ryu, S.H.
The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis
Nat. Cell Biol.
8
477-484
2006
Rattus norvegicus
brenda
Barsoum, M.J.; Yuan, H.; Gerencser, A.A.; Liot, G.; Kushnareva, Y.; Graeber, S.; Kovacs, I.; Lee, W.D.; Waggoner, J.; Cui, J.; White, A.D.; Bossy, B.; Martinou, J.C.; Youle, R.J.; Lipton, S.A.; Ellisman, M.H.; Perkins, G.A.; Bossy-Wetzel, E.
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
EMBO J.
25
3900-3911
2006
Rattus norvegicus
brenda
Sever, S.; Skoch, J.; Newmyer, S.; Ramachandran, R.; Ko, D.; McKee, M.; Bouley, R.; Ausiello, D.; Hyman, B.T.; Bacskai, B.J.
Physical and functional connection between auxilin and dynamin during endocytosis
EMBO J.
25
4163-4174
2006
Rattus norvegicus
brenda
Soulet, F.; Schmid, S.L.; Damke, H.
Domain requirements for an endocytosis-independent, isoform-specific function of dynamin-2
Exp. Cell Res.
312
3539-3545
2006
Homo sapiens, Rattus norvegicus
brenda
Taguchi, N.; Ishihara, N.; Jofuku, A.; Oka, T.; Mihara, K.
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
J. Biol. Chem.
282
11521-11529
2007
Rattus norvegicus
brenda
Newton, A.J.; Kirchhausen, T.; Murthy, V.N.
Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis
Proc. Natl. Acad. Sci. USA
103
17955-17960
2006
Rattus norvegicus
brenda
Hamao, K.; Morita, M.; Hosoya, H.
New function of the proline rich domain in dynamin-2 to negatively regulate its interaction with microtubules in mammalian cells
Exp. Cell Res.
315
1336-1345
2009
Rattus norvegicus (P39052)
brenda
Murphy, J.E.; Vohra, R.S.; Dunn, S.; Holloway, Z.G.; Monaco, A.P.; Homer-Vanniasinkam, S.; Walker, J.H.; Ponnambalam, S.
Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2
J. Cell Sci.
121
2136-2147
2008
Rattus norvegicus (P39052)
brenda
Xu, A.J.; Kuramasu, A.; Maeda, K.; Kinoshita, K.; Takayanagi, S.; Fukushima, Y.; Watanabe, T.; Yanagisawa, T.; Sukegawa, J.; Yanai, K.
Agonist-induced internalization of histamine H2 receptor and activation of extracellular signal-regulated kinases are dynamin-dependent
J. Neurochem.
107
208-217
2008
Rattus norvegicus
brenda
Liu, Y.W.; Surka, M.C.; Schroeter, T.; Lukiyanchuk, V.; Schmid, S.L.
Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells
Mol. Biol. Cell
19
5347-5359
2008
Rattus norvegicus (P21575), Rattus norvegicus (P39052), Rattus norvegicus (Q08877), Homo sapiens (Q05193)
brenda
Rappoport, J.Z.; Heyman, K.P.; Kemal, S.; Simon, S.M.
Dynamics of dynamin during clathrin mediated endocytosis in PC12 cells
PLoS ONE
3
e2416
2008
Rattus norvegicus (P21575), Rattus norvegicus (P39052)
brenda
Ishida, N.; Nakamura, Y.; Tanabe, K.; Li, S.A.; Takei, K.
Dynamin 2 associates with microtubules at mitosis and regulates cell cycle progression
Cell Struct. Funct.
36
145-154
2011
Rattus norvegicus
brenda
Ferguson, S.M.; De Camilli, P.
Dynamin, a membrane-remodelling GTPase
Nat. Rev. Mol. Cell Biol.
13
75-88
2012
Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Zhang, Y.; Nolan, M.; Yamada, H.; Watanabe, M.; Nasu, Y.; Takei, K.; Takeda, T.
Dynamin2 GTPase contributes to invadopodia formation in invasive bladder cancer cells
Biochem. Biophys. Res. Commun.
480
409-414
2016
Rattus norvegicus (P39052), Homo sapiens (P50570), Homo sapiens
brenda
Byers, C.E.; Barylko, B.; Ross, J.A.; Southworth, D.R.; James, N.G.; Taylor, C.A.; Wang, L.; Collins, K.A.; Estrada, A.; Waung, M.; Tassin, T.C.; Huber, K.M.; Jameson, D.M.; Albanesi, J.P.
Enhancement of dynamin polymerization and GTPase activity by Arc/Arg3.1
Biochim. Biophys. Acta
1850
1310-1318
2015
Rattus norvegicus (P21575), Rattus norvegicus (P39052), Rattus norvegicus (Q08877)
brenda
Macdonald, P.J.; Francy, C.A.; Stepanyants, N.; Lehman, L.; Baglio, A.; Mears, J.A.; Qi, X.; Ramachandran, R.
Distinct splice variants of dynamin-related protein 1 differentially utilize mitochondrial fission factor as an effector of cooperative GTPase activity
J. Biol. Chem.
291
493-507
2016
Homo sapiens (O00429), Rattus norvegicus (O35303)
brenda