Reference on EC 3.6.4.B10 - chaperonin ATPase (protein-folding, protecting from aggregation, protein stabilizing)
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Shin, E.J.; Lee, J.W.; Kim, J.H.; Jeon, S.J.; Kim, Y.H.; Nam, S.W.
Overexpression, purification, and characterization of beta-subunit group II chaperonin from hyperthermophilic Aeropyrum pernix K1
J. Microbiol. Biotechnol.
20
542-549
2010
Aeropyrum pernix K1
Yan, Z.; Fujiwara, S.; Kohda, K.; Takagi, M.; Imanaka, T.
In vitro stabilization and in vivo solubilization of foreign proteins by the beta subunit of a chaperonin from the hyperthermophilic archaeon Pyrococcus sp. strain KOD1
Appl. Environ. Microbiol.
63
785-789
1997
Thermococcus kodakarensis (Q52500)
Okochi, M.; Matsuzaki, H.; Nomura, T.; Ishii, N.; Yohda, M.
Molecular characterization of the group II chaperonin from the hyperthermophilic archaeum Pyrococcus horikoshii OT3
Extremophiles
9
127-134
2004
Pyrococcus horikoshii (O57762), Pyrococcus horikoshii OT-3 (O57762)
Franzetti, B.; Schoehn, G.; Ebel, C.; Gagnon, J.; Ruigrok, R.W.; Zaccai, G.
Characterization of a novel complex from halophilic archaebacteria, which displays chaperone-like activities in vitro
J. Biol. Chem.
276
29906-29914
2001
Haloarcula marismortui
Kim, J.H.; Lee, J.W.; Shin, E.J.; Nam, S.W.
Cooperativity of alpha- and beta-subunits of group II chaperonin from the hyperthermophilic archaeum Aeropyrum pernix K1
J. Microbiol. Biotechnol.
21
212-217
2011
Aeropyrum pernix (Q9YDK6 and Q9YA66), Aeropyrum pernix, Aeropyrum pernix DSM 11879 (Q9YDK6 and Q9YA66)
Lee, J.W.; Kim, S.W.; Kim, J.H.; Jeon, S.J.; Kwon, H.J.; Kim, B.W.; Nam, S.W.
Functional characterization of the alpha- and beta-subunits of a group II chaperonin from Aeropyrum pernix K1
J. Microbiol. Biotechnol.
23
818-825
2013
Aeropyrum pernix (Q9YA66), Aeropyrum pernix (Q9YDK6), Aeropyrum pernix (Q9YDK6 and Q9YA66), Aeropyrum pernix DSM 11879 (Q9YDK6 and Q9YA66)
Gao, L.; Danno, A.; Fujii, S.; Fukuda, W.; Imanaka, T.; Fujiwara, S.
Indole-3-glycerol-phosphate synthase is recognized by a cold-inducible group II chaperonin in Thermococcus kodakarensis
Appl. Environ. Microbiol.
78
3806-3815
2012
Thermococcus kodakarensis (P61111), Thermococcus kodakarensis (Q52500)
Jayasinghe, M.; Shrestha, P.; Wu, X.; Tehver, R.; Stan, G.
Weak intra-ring allosteric communications of the archaeal chaperonin thermosome revealed by normal mode analysis
Biophys. J.
103
1285-1295
2012
Thermoplasma acidophilum (P48424), Thermoplasma acidophilum (P48425), Thermoplasma acidophilum ATCC 25905 (P48424), Thermoplasma acidophilum ATCC 25905 (P48425)
Cong, Y.; Schroeder, G.; Meyer, A.; Jakana, J.; Ma, B.; Dougherty, M.; Schmid, M.; Reissmann, S.; Levitt, M.; Ludtke, S.; Frydman, J.; Chiu, W.
Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle
EMBO J.
31
720-730
2012
Bos taurus
Skjaerven, L.; Cuellar, J.; Martinez, A.; Valpuesta, J.M.
Dynamics, flexibility, and allostery in molecular chaperonins
FEBS Lett.
589
2522-2532
2015
Saccharomyces cerevisiae (P12612), Thermoplasma acidophilum (P48424), Thermoplasma acidophilum (P48425), Bos taurus (Q32L40), Methanococcus maripaludis (Q877G8), Saccharomyces cerevisiae ATCC 204508 (P12612), Thermoplasma acidophilum ATCC 25905 (P48424), Thermoplasma acidophilum ATCC 25905 (P48425)
Gao, L.; Imanaka, T.; Fujiwara, S.
A mutant chaperonin that is functional at lower temperatures enables hyperthermophilic Archaea to grow under cold-stress conditions
J. Bacteriol.
197
2642-2652
2015
Thermococcus kodakarensis (P61111), Thermococcus kodakarensis (Q52500), Thermococcus kodakarensis KU216 (Q52500)
Hongo, K.; Itai, H.; Mizobata, T.; Kawata, Y.
Varied effects of Pyrococcus furiosus prefoldin and P. furiosus chaperonin on the refolding reactions of substrate proteins
J. Biochem.
151
383-390
2012
Pyrococcus furiosus
Yamamoto, Y.Y.; Abe, Y.; Moriya, K.; Arita, M.; Noguchi, K.; Ishii, N.; Sekiguchi, H.; Sasaki, Y.C.; Yohda, M.
Inter-ring communication is dispensable in the reaction cycle of group II chaperonins
J. Mol. Biol.
426
2667-2678
2014
Thermococcus sp. (O24730), Thermococcus sp. (P61112), Thermococcus sp. KS-1 (O24730), Thermococcus sp. KS1 (P61112)
Nakagawa, A.; Moriya, K.; Arita, M.; Yamamoto, Y.; Kitamura, K.; Ishiguro, N.; Kanzaki, T.; Oka, T.; Makabe, K.; Kuwajima, K.; Yohda, M.
Dissection of the ATP-dependent conformational change cycle of a group II chaperonin
J. Mol. Biol.
426
447-459
2014
Thermococcus sp. (O24730), Thermococcus sp. (P61112), Thermococcus sp. KS-1 (O24730), Thermococcus sp. KS-1 (P61112)
Lopez, T.; Dalton, K.; Frydman, J.
The mechanism and function of group II chaperonins
J. Mol. Biol.
427
2919-2930
2015
Saccharomyces cerevisiae, Methanococcus maripaludis, Thermoplasma acidophilum
Sekiguchi, H.; Nakagawa, A.; Moriya, K.; Makabe, K.; Ichiyanagi, K.; Nozawa, S.; Sato, T.; Adachi, S.; Kuwajima, K.; Yohda, M.; Sasaki, Y.C.
ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking
PLoS ONE
8
e64176
2013
Thermococcus sp. (O24730), Thermococcus sp. (P61112), Thermococcus sp. KS-1 (O24730), Thermococcus sp. KS-1 (P61112)
Kim, J.; Shin, E.; Jeon, S.; Kim, Y.; Kim, P.; Lee, C.; Nam, S.
Overexpression, purification, and functional characterization of the group II chaperonin from the hyperthermophilic archaeum Pyrococcus horikoshii OT3
Biotechnol. Bioprocess Eng.
14
551-558
2009
Pyrococcus horikoshii (O57762)
-
Willison, K.R.
The structure and evolution of eukaryotic chaperonin-containing TCP-1 and its mechanism that folds actin into a protein spring
Biochem. J.
475
3009-3034
2018
Mus musculus (P11983 AND P80314 AND P80318 AND P80315 AND P80316 AND P80317 AND P80313 AND P42932), Saccharomyces cerevisiae (P12612 AND P39076 AND P39077 AND P39078 AND P40413 AND P39079 AND P42943 AND P47079), Drosophila melanogaster (P12613 AND Q9W392 AND P48605 AND Q9VK69 AND Q7KKI0 AND Q9VXQ5 AND Q9VHL2 AND Q7K3J0), Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990), Rattus norvegicus (P28480 AND Q5XIM9 AND Q6P502 AND Q7TPB1 AND Q68FQ0 AND Q3MHS9 AND D4AC23 AND D4ACB8), Arabidopsis thaliana (P28769 AND Q940P8 AND Q84WV1 AND Q9LV21 AND O04450 AND Q9M888 AND Q9SF16 AND Q94K05), Caenorhabditis elegans (P41988 AND P47207 AND Q9N4J8 AND P47208 AND P47209 AND P46550 AND Q9TZS5 AND Q9N358), Bos taurus (Q32L40 AND Q3ZBH0 AND Q3T0K2 AND F1N0E5 AND F1MWD3 AND Q3MHL7 AND Q2NKZ1 AND Q3ZCI9), Dictyostelium discoideum (Q55BM4 AND Q54ES9 AND Q54TH8 AND Q54CL2 AND Q54TD3 AND Q76NU3 AND Q54ER7 AND Q552J0), Candida albicans (Q59QB7 AND Q59YC4 AND Q5AK16 AND Q59Z12 AND A0A1D8PMN9 AND Q59YH4 AND P47828), Plasmodium falciparum (Q8II43 AND O97247 AND Q8I5C4 AND C0H5I7 AND O97282 AND C6KST5 AND O77323 AND O96220), Danio rerio (Q9PW76 AND Q6PBW6 AND Q7T2P2 AND Q6P123 AND Q6NVI6 AND E9QGU4 AND B3DKJ0 AND A0A0R4IJT8), Rattus norvegicus Sprague-Dawley (P28480 AND Q5XIM9 AND Q6P502 AND Q7TPB1 AND Q68FQ0 AND Q3MHS9 AND D4AC23 AND D4ACB8), Candida albicans ATCC MYA-2876 (Q59QB7 AND Q59YC4 AND Q5AK16 AND Q59Z12 AND A0A1D8PMN9 AND Q59YH4 AND P47828), Saccharomyces cerevisiae ATCC 204508 (P12612 AND P39076 AND P39077 AND P39078 AND P40413 AND P39079 AND P42943 AND P47079)
Korobko, I.; Nadler-Holly, M.; Horovitz, A.
Transient kinetic analysis of ATP hydrolysis by the CCT/TRiC chaperonin
J. Mol. Biol.
428
4520-4527
2016
Saccharomyces cerevisiae (P12612 AND P39076 AND P39077 AND P39078 AND P40413 AND P39079 AND P42943 AND P47079), Saccharomyces cerevisiae ATCC 204508 (P12612 AND P39076 AND P39077 AND P39078 AND P40413 AND P39079 AND P42943 AND P47079)
Araki, K.; Suenaga, A.; Kusano, H.; Tanaka, R.; Hatta, T.; Natsume, T.; Fukui, K.
Functional profiling of asymmetrically-organized human CCT/TRiC chaperonin
Biochem. Biophys. Res. Commun.
481
232-238
2016
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990), Homo sapiens
Roh, S.H.; Kasembeli, M.M.; Galaz-Montoya, J.G.; Chiu, W.; Tweardy, D.J.
Chaperonin TRiC/CCT recognizes fusion oncoprotein AML1-ETO through subunit-specific interactions
Biophys. J.
110
2377-2385
2016
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990)
Balchin, D.; Milicic, G.; Strauss, M.; Hayer-Hartl, M.; Hartl, F.U.
Pathway of actin folding directed by the eukaryotic chaperonin TRiC
Cell
174
1507-1521.e16
2018
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990)
Gestaut, D.; Roh, S.H.; Ma, B.; Pintilie, G.; Joachimiak, L.A.; Leitner, A.; Walzthoeni, T.; Aebersold, R.; Chiu, W.; Frydman, J.
The chaperonin TRiC/CCT associates with prefoldin through a conserved electrostatic interface essential for cellular proteostasis
Cell
177
751-765.e15
2019
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990)
Berger, J.; Berger, S.; Li, M.; Jacoby, A.S.; Arner, A.; Bavi, N.; Stewart, A.G.; Currie, P.D.
In vivo function of the chaperonin TRiC in beta-actin folding during sarcomere assembly
Cell Rep.
22
313-322
2018
Danio rerio (Q9PW76 AND Q6PBW6 AND Q7T2P2 AND Q6P123 AND Q6NVI6 AND E9QGU4 AND B3DKJ0 AND A0A0R4IJT8)
Yusof, N.A.; Kamaruddin, S.; Abu Bakar, F.D.; Mahadi, N.M.; Abdul Murad, A.M.
Structural and functional insights into TRiC chaperonin from a psychrophilic yeast, Glaciozyma antarctica
Cell Stress Chaperones
24
351-368
2019
Glaciozyma antarctica (A0A1S6LQX4 AND A0A1S6LQU3 AND A0A1S6LQU0 AND A0A1S6LQU6 AND A0A1S6LQU1 AND A0A1S6LQU9 AND A0A1S6LQW6 AND A0A1S6LQW7), Glaciozyma antarctica
Spillman, N.J.; Beck, J.R.; Ganesan, S.M.; Niles, J.C.; Goldberg, D.E.
The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol
Cell. Microbiol.
19
e12719
2017
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990), Plasmodium falciparum (Q8II43 AND O97247 AND Q8I5C4 AND C0H5I7 AND O97282 AND C6KST5 AND O77323 AND O96220), Plasmodium falciparum
Guest, S.T.; Kratche, Z.R.; Bollig-Fischer, A.; Haddad, R.; Ethier, S.P.
Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes
Exp. Cell Res.
332
223-235
2015
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990), Homo sapiens
Melkani, G.C.; Bhide, S.; Han, A.; Vyas, J.; Livelo, C.; Bodmer, R.; Bernstein, S.I.
TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and lifespan
FEBS Lett.
591
3447-3458
2017
Drosophila melanogaster (P12613 AND Q9W392 AND P48605 AND Q9VK69 AND Q7KKI0 AND Q9VXQ5 AND Q9VHL2 AND Q7K3J0)
Roh, S.H.; Kasembeli, M.; Bakthavatsalam, D.; Chiu, W.; Tweardy, D.J.
Contribution of the type II chaperonin, TRiC/CCT, to oncogenesis
Int. J. Mol. Sci.
16
26706-26720
2015
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990), Bos taurus (Q32L40 AND Q3ZBH0 AND Q3T0K2 AND F1N0E5 AND F1MWD3 AND Q3MHL7 AND Q2NKZ1 AND Q3ZCI9)
Shah, R.; Large, A.T.; Ursinus, A.; Lin, B.; Gowrinathan, P.; Martin, J.; Lund, P.A.
Replacement of GroEL in Escherichia coli by the group II chaperonin from the archaeon Methanococcus maripaludis
J. Bacteriol.
198
2692-2700
2016
Methanococcus maripaludis (Q877G8)
Roh, S.H.; Kasembeli, M.; Galaz-Montoya, J.G.; Trnka, M.; Lau, W.C.; Burlingame, A.; Chiu, W.; Tweardy, D.J.
Chaperonin TRiC/CCT modulates the folding and activity of leukemogenic fusion oncoprotein AML1-ETO
J. Biol. Chem.
291
4732-4741
2016
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990), Bos taurus (Q32L40 AND Q3ZBH0 AND Q3T0K2 AND F1N0E5 AND F1MWD3 AND Q3MHL7 AND Q2NKZ1 AND Q3ZCI9)
Zako, T.; Sahlan, M.; Fujii, S.; Yamamoto, Y.Y.; Tai, P.T.; Sakai, K.; Maeda, M.; Yohda, M.
Contribution of the C-terminal region of a group II chaperonin to its interaction with prefoldin and substrate transfer
J. Mol. Biol.
428
2405-2417
2016
Thermococcus sp. JCM 11816 (P61112 AND O24730)
Kim, S.; Lee, D.; Lee, J.; Song, H.; Kim, H.J.; Kim, K.T.
Vaccinia-related kinase 2 controls the stability of the eukaryotic chaperonin TRiC/CCT by inhibiting the deubiquitinating enzyme USP25
Mol. Cell. Biol.
35
1754-1762
2015
Mus musculus (P11983 AND P80314 AND P80318 AND P80315 AND P80316 AND P80317 AND P80313 AND P42932)
Knowlton, J.J.; Fernandez de Castro, I.; Ashbrook, A.W.; Gestaut, D.R.; Zamora, P.F.; Bauer, J.A.; Forrest, J.C.; Frydman, J.; Risco, C.; Dermody, T.S.
The TRiC chaperonin controls reovirus replication through outer-capsid folding
Nat. Microbiol.
3
481-493
2018
Homo sapiens (P17987 AND P78371 AND P49368 AND P50991 AND P48643 AND P40227 AND Q99832 AND P50990)
Zang, Y.; Jin, M.; Wang, H.; Cui, Z.; Kong, L.; Liu, C.; Cong, Y.
Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM
Nat. Struct. Mol. Biol.
23
1083-1091
2016
Saccharomyces cerevisiae (P12612 AND P39076 AND P39077 AND P39078 AND P40413 AND P39079 AND P42943 AND P47079), Saccharomyces cerevisiae
Kim, A.R.; Choi, K.W.
TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila
Oncogene
38
4739-4754
2019
Drosophila melanogaster (P12613 AND Q9W392 AND P48605 AND Q9VK69 AND Q7KKI0 AND Q9VXQ5 AND Q9VHL2 AND Q7K3J0)
Ohhara, Y.; Nakamura, A.; Kato, Y.; Yamakawa-Kobayashi, K.
Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila
PLoS Genet.
15
e1008121
2019
Drosophila melanogaster (P12613 AND Q9W392 AND P48605 AND Q9VK69 AND Q7KKI0 AND Q9VXQ5 AND Q9VHL2 AND Q7K3J0), Drosophila melanogaster Oregon R (P12613 AND Q9W392 AND P48605 AND Q9VK69 AND Q7KKI0 AND Q9VXQ5 AND Q9VHL2 AND Q7K3J0)
Yamamoto, Y.Y.; Uno, Y.; Sha, E.; Ikegami, K.; Ishii, N.; Dohmae, N.; Sekiguchi, H.; Sasaki, Y.C.; Yohda, M.
Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC
PLoS ONE
12
e0176054
2017
Thermochaetoides thermophila
Moparthi, S.B.; Carlsson, U.; Vincentelli, R.; Jonsson, B.H.; Hammarstroem, P.; Wenger, J.
Differential conformational modulations of MreB folding upon interactions with GroEL/ES and TRiC chaperonin components
Sci. Rep.
6
28386
2016
Bos taurus (Q32L40 AND Q3ZBH0 AND Q3T0K2 AND F1N0E5 AND F1MWD3 AND Q3MHL7 AND Q2NKZ1 AND Q3ZCI9)
html completed
