Information on EC 3.6.4.6 - vesicle-fusing ATPase

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The expected taxonomic range for this enzyme is: Eukaryota, Archaea

EC NUMBER
COMMENTARY
3.6.4.6
-
RECOMMENDED NAME
GeneOntology No.
vesicle-fusing ATPase
SYSTEMATIC NAME
IUBMB Comments
ATP phosphohydrolase (vesicle-fusing)
A large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (_A_TPase _a_ssociated with a variety of cell _a_ctivities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger's syndrome.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
AAA ATPase Vps4
-
-
AAA ATPase Vps4
Q97ZJ7
-
AAA ATPase Vps4
Q97ZJ7
-
-
AAA-ATPase
P52917
-
ATP phosphohydrolase
-
-
ATP phosphohydrolase
-
-
ATPase N-ethylmaleimide sensitive factor
-
-
dNSF1
-
isoform 1
dNSF1
P46461
isoform 2
Hez-NSF
-
-
HsPEX1
-
-
HsPex1p
-
-
membrane deformation AAA ATPase
-
-
N-ethyl maleimide sensitive factor
-
-
N-ethylmaleimide sensitive factor
-
-
N-ethylmaleimide sensitive factor
-, P46461
-
N-ethylmaleimide sensitive factor
-
-
N-ethylmaleimide sensitive factor
-
-
N-ethylmaleimide sensitive factor
-
-
N-ethylmaleimide sensitive fusion protein
-
-
-
-
N-ethylmaleimide sensitive fusion protein
-
-
N-ethylmaleimide sensitive-factor
-
-
N-ethylmaleimide sensitive-factor
-
-
N-ethylmaleimide-sensitive factor
-
-
N-ethylmaleimide-sensitive factor
-
-
N-ethylmaleimide-sensitive factor
-
-
N-ethylmaleimide-sensitive fusion protein
-
-
N-ethylmaleimide-sensitive fusion protein
-
-
N-ethylmaleimide-sensitive fusion protein
-
-
N-ethylmaleimide-sensitive fusion protein
-
-
N-ethylmeleimide-sensitive factor
-
-
NEM-sensitive fusion protein
-
-
-
-
NEM-sensitive fusion protein
-
-
NSF
-
-
NSF
-
-
NSF protein
-
N-ethyl-maleimide-sensitive fusion protein
NSF protein
-
-
NSF protein
-
N-ethyl-maleimide-sensitive fusion protein
NSF-1
-
there are two NSF-1 isoforms, which are expressed in distinct tissues through two separate promoters
p97
protozoa
-
-
p97/VCP/Cdc48p
-
-
p97/VCP/Cdc48p homologue
-
-
p97ATPase
-
-
peptide p97
P46462
essential chaperone in endoplasmic reticulum-associated degradation and organelle biogenesis, contains two ATPases associated with various cellular activities domains (D1 and D2)
Pex1p
-
-
Pex6p
-
-
rat Pex6p
-
-
SEC18 gene product
-
-
SEC18p
-
-
SKD1/VPS4B
P46467
-
SKD2 protein
-
-
-
-
Sso0909
Q97ZJ7
locus name
Sso0909
Q97ZJ7
locus name
-
SsoVps4
Q97ZJ7
-
SsoVps4
Q97ZJ7
-
-
suppresor of potassium transport growth defect
-
-
vacular protein sorting 4 B
-
-
vacuolar protein sorting 4
-
-
vacuolar protein sorting 4
Q97ZJ7
-
vacuolar protein sorting 4
Q97ZJ7
-
-
vacuolar protein sorting 4 protein
P52917
-
vasolin-containing protein
P46462
-
VCP
P46462
-
vesicle-fusing ATPase
-
-
vesicle-fusing ATPase
-
-
Vesicular-fusion protein NSF
-
-
-
-
Vps 4B
-
-
VPS4 gene product
-
-
Vps4p
-
a type I ATPase associated with a variety of cellular activities ATPase
Vps4p AAA ATPase
-
-
CAS REGISTRY NUMBER
COMMENTARY
9000-83-3
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
long-tailed hamster
-
-
Manually annotated by BRENDA team
HeLa cells; human embryonic kidney HEK293 cells; human epidermoid carcinoma A-431 cells
-
-
Manually annotated by BRENDA team
protozoa
-
-
-
Manually annotated by BRENDA team
rat; rat hepatoma H-4-II-E cells
-
-
Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)