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Disease on EC 3.6.1.9 - nucleotide diphosphatase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Radiation Syndrome
DEVELOPMENT OF A NATIONAL EMERGENCY PLAN FOR MEDICAL DIAGNOSTICS AND THERAPY OF DETERMINISTIC EFFECTS AFTER RADIATION ACCIDENTS.
Persistent infections and their relationship with selected oncologic and non-tumor pathologies.
adenosine deaminase deficiency
Inosine triphosphate pyrophosphohydrolase deficiency in a kindred with adenosine deaminase deficiency.
Adrenocortical Carcinoma
The antibody-drug conjugate target landscape across a broad range of tumour types.
Airway Obstruction
Drug-induced sleep endoscopy: new insights in lateral head rotation compared to lateral head and trunk rotation in (non)positional obstructive sleep apnea patients.
Anaphylaxis
A case of anaphylaxis to erythritol diagnosed by CD203c expression-based basophil activation test.
Anaphylaxis caused by butylscopolamine bromide: a case report.
CD203c expression-based basophil activation test for diagnosis of wheat-dependent exercise-induced anaphylaxis.
Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
Diagnostic utility of the basophil activation test in natto-induced hypersensitivity.
Evaluation of Basophil CD203c as a Predictor of Carboplatin-Related Hypersensitivity Reaction in Patients with Gynecologic Cancer.
Flow cytometric investigation of peri-anaesthetic anaphylaxis using CD63 and CD203c.
Hypersensitivity to fluoroquinolones: The expression of basophil activation markers depends on the clinical entity and the culprit fluoroquinolone.
Identification and Physicochemical Characterization of a New Allergen from Ascaris lumbricoides.
Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis.
Anemia
A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms.
An index to predict ribavirin-induced anemia in asian patients with chronic genotype 1 hepatitis C.
Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.
Association between inosine triphosphatase rs1127354 polymorphisms and ribavirin-induced anaemia and outcome in hepatitis C virus-infected patients: A meta-analysis.
Effect of gender and ITPA polymorphisms on ribavirin-induced anemia in chronic hepatitis C patients.
Effectiveness and safety of sofosbuvir plus ribavirin for HCV genotype 2 patients 65 and over with or without cirrhosis.
Effects of ribavirin/sofosbuvir treatment and ITPA phenotype on endogenous purines.
Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype.
Estimated glomerular filtration rate but not solute carrier polymorphisms influences anemia in HIV-hepatitis C virus coinfected patients treated with boceprevir or telaprevir-based therapy.
Gene expression profiles associated with anaemia and ITPA genotypes in patients with chronic hepatitis C (CH-C).
Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection.
Impact of inosine triphosphatase gene variants on the risk of anemia in HIV/hepatitis C virus-coinfected patients treated for chronic hepatitis C.
Increase in platelet count based on inosine triphosphatase genotype during interferon beta plus ribavirin combination therapy.
Induction of inosine triphosphatase activity during ribavirin treatment for chronic hepatitis C.
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Inosine triphosphatase allele frequency and association with ribavirin-induced anaemia in Brazilian patients receiving antiviral therapy for chronic hepatitis C.
Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy.
Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR.
Inosine Triphosphatase Polymorphisms and Ribavirin Pharmacokinetics as Determinants of Ribavirin-Associate Anemia in Patients Receiving Standard Anti-HCV Treatment.
Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function.
Inosine triphosphate pyrophosphatase polymorphisms are predictors of anemia in Chinese patients with chronic hepatitis C during therapy with ribavirin and interferon.
Inosine triphosphate pyrophosphohydrolase activity: more accurate predictor for ribavirin-induced anemia in hepatitis C infected patients than ITPA genotype.
ITPA deficiency and ribavirin level are still predictive of anaemia in HCV-HIV-coinfected patients receiving ribavirin combined with a first-generation DAA (ANRS HC27 study).
ITPA gene polymorphism (94C>A) effects on ribavirin-induced anemia during therapy in Egyptian patients with chronic hepatitis C.
ITPA gene variant may protect against anemia induced during pegylated interferon alfa and ribavirin combination treatment in Ukrainian patients with chronic hepatitis C.
ITPA genetic variants influence efficacy of PEG-IFN/RBV therapy in older patients infected with HCV genotype 1 and favourable IL28B type.
ITPA Genotype Protects Against Anemia During Peginterferon And Ribavirin Therapy But Does Not Influence Virological Response.
ITPA Genotypes Predict Anemia but Do Not Affect Virological Response with Interferon-Free Faldaprevir, Deleobuvir, and Ribavirin for HCV Infection.
ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
ITPA polymorphism effects on decrease of hemoglobin during simeprevir, pegylated interferon and ribavirin combination treatment for chronic hepatitis C.
ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.
ITPase activity modulates the severity of anaemia in HCV-related cirrhosis treated with ribavirin-containing interferon-free regimens.
Limited utility of ITPA deficiency to predict early anemia in HCV patients with advanced fibrosis receiving Telaprevir.
Management of anemia induced by triple therapy in patients with chronic hepatitis C: Challenges, opportunities and recommendations.
Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C.
Pharmacological exposure to ribavirin: A key player in the complex network of factors implicated in virological response and anaemia in hepatitis C treatment.
Polymorphism of the inosine triphosphate pyrophosphatase gene predicts ribavirin-induced anemia in chronic hepatitis C patients.
Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.
Protease inhibitors-based therapy induces acquired spherocytic-like anaemia and ineffective erythropoiesis in chronic hepatitis C virus patients.
Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens.
Relationship between ITPA polymorphisms and hemolytic anemia in HCV-infected patients after ribavirin-based therapy: a meta-analysis.
Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin.
Role of genetic polymorphisms in hepatitis C virus chronic infection.
Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection.
Role of ITPA and IL28B variants in the management of chronic hepatitis C treatment.
Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.
Roles of ITPA and IL28B genotypes in chronic hepatitis C patients treated with peginterferon plus ribavirin.
The role of ITPA and ribavirin transporter genes polymorphisms in prediction of ribavirin-induced anaemia in chronic hepatitis C Egyptian patients.
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction.
Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.
Viral and host factors associated with outcomes of hepatitis C virus infection (Review).
[Genetic polymorphisms as predictors of response to antiviral treatment in chronic hepatitis C virus infection].
[Genome-wide association study on and the clinical application to chronic hepatitis C].
Anemia, Hemolytic
Allelic inhibition of displacement activity: a simplified one tube allele-specific PCR for evaluation of ITPA polymorphisms.
Association of ITPA gene variation and serum ribavirin concentration with a decline in blood cell concentrations during pegylated interferon-alpha plus ribavirin therapy for chronic hepatitis C.
Association of ITPA polymorphisms rs6051702/rs1127354 instead of rs7270101/rs1127354 as predictor of ribavirin-associated anemia in chronic hepatitis C treated patients.
Comparison of three different methods for the evaluation of IL28 and ITPA polymorphisms in patients infected with HCV.
Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.
High Prevalence of ITPA Alleles Associated with Ribavirin-Induced Hemolytic Anemia Among Mexican Population.
Host genetic variants in the pathogenesis of hepatitis C.
Individualized Therapy for Hepatitis C Infection: Focus on the Interleukin-28B Polymorphism in Directing Therapy.
Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR.
Inosine Triphosphatase Polymorphisms and Ribavirin Pharmacokinetics as Determinants of Ribavirin-Associate Anemia in Patients Receiving Standard Anti-HCV Treatment.
Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus.
ITPA gene polymorphisms significantly affect hemoglobin decline and treatment outcomes in patients coinfected with HIV and HCV.
ITPA gene variant protects against anemia induced by pegylated interferon-? and ribavirin therapy for Japanese patients with chronic hepatitis C.
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.
ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin.
ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection.
Protease inhibitors-based therapy induces acquired spherocytic-like anaemia and ineffective erythropoiesis in chronic hepatitis C virus patients.
Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens.
Relationship between ITPA polymorphisms and hemolytic anemia in HCV-infected patients after ribavirin-based therapy: a meta-analysis.
The impact of human gene polymorphisms on HCV infection and disease outcome.
The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.
Variant Inosine Triphosphatase Phenotypes Are Associated With Increased Ribavirin Triphosphate Levels.
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction.
Angioedema
Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
Ankylosis
Regulation of cementoblast gene expression by inorganic phosphate in vitro.
Apnea
Comparison of nasal prong pressure and thermistor measurements for detecting respiratory events during sleep.
Positional vs nonpositional obstructive sleep apnea patients: anthropomorphic, nocturnal polysomnographic, and multiple sleep latency test data.
Role of nasal problems on positional and nonpositional obstructive sleep apnea.
Arthritis
Calcium pyrophosphate crystal deposition disease and other crystal deposition diseases.
Arthritis, Rheumatoid
Activities of enzymes that hydrolyze adenine nucleotides in platelets from patients with rheumatoid arthritis.
Synovial fluid pyrophosphate and nucleoside triphosphate pyrophosphatase: comparison between normal and diseased and between inflamed and non-inflamed joints.
Asbestosis
Mesothelioma mortality within two radiation monitored occupational cohorts.
Aspergillosis, Allergic Bronchopulmonary
Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis in cystic fibrosis.
Asthma
CD203c expression on human basophils is associated with asthma exacerbation.
Decreased expression of ectonucleotidase E-NPP1 in leukocytes from subjects with severe asthma exacerbation.
Effects of prostaglandin D(2) and 5-lipoxygenase products on the expression of CD203c and CD11b by basophils.
Expression of Basophil Activation Markers in Pediatric Asthma.
The utility of the basophil activation test in differentiating asthmatic subjects with and without allergic bronchopulmonary aspergillosis.
Autoimmune Diseases
NUDT15 and TPMT Genetic Polymorphisms Are Related to Azathioprine Intolerance in Chinese Patients with Rheumatic Diseases.
Red Blood cell IMPDH activity in adults and children with or without azathioprine: Relationship between thiopurine metabolites, ITPA and TPMT activities.
Azoospermia
Yeast model identifies ENTPD6 as a potential non-obstructive azoospermia pathogenic gene.
Bile Duct Diseases
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases.
Botulism
Botulinum neurotoxin inhibitor binding dynamics and kinetics relevant for drug design.
Brain Diseases
A novel ITPA variant causes epileptic encephalopathy with multiple-organ dysfunction.
[Interdepartmental division of functional biochemistry]
Brain Ischemia
Recent advance and possible future in TREK-2: a two-pore potassium channel may involved in the process of NPP, brain ischemia and memory impairment.
Breast Neoplasms
Differential expression of nucleotide pyrophosphatase/phosphodiesterases by Walker 256 mammary cancer cells in solid tumors and malignant ascites.
Carcinogenesis
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-I beta/B10/gp130RB13-6) in human colon carcinoma.
Understanding the molecular activity of alkaline sphingomyelinase (NPP7) by computer modeling.
Carcinoma
AGS16F Is a Novel Antibody Drug Conjugate Directed against ENPP3 for the Treatment of Renal Cell Carcinoma.
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases.
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-I beta/B10/gp130RB13-6) in human colon carcinoma.
Carcinoma, Hepatocellular
Cell-type specificity of ectonucleotidase expression and upregulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Carcinoma, Renal Cell
AGS16F Is a Novel Antibody Drug Conjugate Directed against ENPP3 for the Treatment of Renal Cell Carcinoma.
Cardiomyopathy, Dilated
ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy.
Cardiovascular Diseases
Mechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors.
THE ASSESSMENT OF COMORBID PATHOLOGY IN CLEAN-UP WORKERS OF THE ACCIDENT CONSEQUENCES AT THE CHORNOBYL NPP HAVING CARDIOVASCULAR DISEASES.
Castleman Disease
Siltuximab in relapsed/refractory multicentric Castleman disease: Experience of the Italian NPP program.
Cataract
Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.
Cholesteatoma
The accuracy and sensitivity of diffusion-weighted magnetic resonance imaging with Apparent Diffusion Coefficients in diagnosis of recurrent cholesteatoma.
Chondrocalcinosis
Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1. Relevance to calcium pyrophosphate dihydrate deposition disease.
Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes.
Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta.
Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs.
The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles.
[Mechanism of crystal deposition in the joints]
Choriocarcinoma
Expression of ENPP3 in human cyclic endometrium: a novel molecule involved in embryo implantation.
Chronic Urticaria
Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria.
Chronic urticaria sera increase basophil CD203c expression.
Improved Fc?RI-Mediated CD203c Basophil Responsiveness Reflects Rapid Responses to Omalizumab in Chronic Spontaneous Urticaria.
Increased level of basophil CD203c expression predicts severe chronic urticaria.
The autoimmune nature of chronic urticaria.
Coccidiosis
The interactive effects of Eimeria acervulina infection and phytase for broiler chicks.
Coinfection
Impact of inosine triphosphatase gene variants on the risk of anemia in HIV/hepatitis C virus-coinfected patients treated for chronic hepatitis C.
Myastenia and small doses of ionizing radiation: experience of successful use of rituximab for treatment of an irradiated with myasthenia gravis.
Colitis, Ulcerative
Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan.
Colonic Neoplasms
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-I beta/B10/gp130RB13-6) in human colon carcinoma.
Identification of two novel tumor-associated antigens recognized by HLA-B46-restricted cytotoxic T lymphocytes.
Coronary Disease
Analysis of some risk factors for myocardial infarction in a cohort of the Chornobyl clean-up workers (according to the data of Clinical and Epidemiological Registry).
ENPP1 K121Q (rs1044498?C?>?A) genetic polymorphism confers a high risk of susceptibility to coronary heart disease: A PRISMA-compliant article.
Structural and functional state of heart left ventricle depending on polymorphism rs966221 phosphodiesterase 4D gene in emergency workers of the Chornobyl NPP suffering from coronary heart disease.
Crohn Disease
Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.
Sequential evaluation of thiopurine methyltransferase, inosine triphosphate pyrophosphatase, and HPRT1 genes polymorphisms to explain thiopurines' toxicity and efficacy.
Cystic Fibrosis
Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis in cystic fibrosis.
CD203c in patients with cystic fibrosis and allergy to Aspergillus fumigatus.
The basophil surface marker CD203c identifies Aspergillus species sensitization in patients with cystic fibrosis.
Cysts
Analysis of the ectoenzymes ADA, ALP, ENPP1, and ENPP3, in the contents of ovarian endometriomas as candidate biomarkers of endometriosis.
dctp diphosphatase deficiency
A Japanese case with inosine triphosphate pyrophosphohydrolase deficiency attributable to an enzymatic defect in white blood cells.
Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients.
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population.
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.
Inosine triphosphate pyrophosphohydrolase deficiency in a kindred with adenosine deaminase deficiency.
PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification.
Dehydration
A simulation model of Bouteloua gracilis biomass dynamics on the North American shortgrass prairie.
Assessing the effects of management on forest growth across France: insights from a new functional-structural model.
Leaf-traits and growth allometry explain competition and differences in response to climatic change in a temperate forest landscape: a simulation study.
Response of net primary production to land use and climate changes in the middle-reaches of the Heihe River Basin.
The effect of water stress on net primary productivity in northwest China.
[Biochemical changes in the brain of the root vole (Microtus oeconomus) from a 30-kilometer zone around the Chernobyl Atomic Electric Power Station]
Dental Caries
ORAL HYGIENE IN CHILDREN WITH DISTURBANCES IN TOOTH FORMATION WHO WERE AFFECTED AS A CONSEQUENCE OF THE ChNPP ACCIDENT.
Diabetes Mellitus
MORPHOLOGICAL AND FUNCTIONAL MYOCARDIAL ABNORMALITIES IN THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS OF «IODINE» PERIOD HAVING GOT TYPE 2 DIABETES MELLITUS.
Diabetes Mellitus, Type 2
Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity.
Mechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors.
MORPHOLOGICAL AND FUNCTIONAL MYOCARDIAL ABNORMALITIES IN THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS OF «IODINE» PERIOD HAVING GOT TYPE 2 DIABETES MELLITUS.
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family.
Synthesis, biological evaluation, and docking studies of novel pyrrolo[2,3-b]pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents.
Diabetes, Gestational
Decreased insulin receptor tyrosine kinase activity and plasma cell membrane glycoprotein-1 overexpression in skeletal muscle from obese women with gestational diabetes mellitus (GDM): evidence for increased serine/threonine phosphorylation in pregnancy and GDM.
Diphtheria
Novel basophil- or eosinophil-depleted mouse models for functional analyses of allergic inflammation.
Drug Hypersensitivity
Diagnostic tests based on human basophils: potentials, pitfalls and perspectives.
Drug-Related Side Effects and Adverse Reactions
Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).
Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in exon 6.
Association between inosine triphosphatase rs1127354 polymorphisms and ribavirin-induced anaemia and outcome in hepatitis C virus-infected patients: A meta-analysis.
Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients.
Determination of inosine triphosphate pyrophosphatase phenotype in human red blood cells using HPLC.
Determination of ITPase activity in erythrocyte lysates obtained for determination of TPMT activity.
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.
Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation.
Pharmacogenetic significance of inosine triphosphatase.
Relevance of pharmacogenetic aspects of mercaptopurine metabolism in the treatment of interstitial lung disease.
Sequential evaluation of thiopurine methyltransferase, inosine triphosphate pyrophosphatase, and HPRT1 genes polymorphisms to explain thiopurines' toxicity and efficacy.
The effect of ITPA polymorphisms on the enzyme kinetic properties of human erythrocyte inosine triphosphatase toward its substrates ITP and 6-Thio-ITP.
Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.
Encephalomyelitis
Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia.
Endocrine System Diseases
Peculiarities of non-malignant endocrine disease in the Chornobyl NPP accident survivors, and hormonal interaction role.
Endometriosis
Analysis of the ectoenzymes ADA, ALP, ENPP1, and ENPP3, in the contents of ovarian endometriomas as candidate biomarkers of endometriosis.
Exanthema
Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine.
Fatty Liver
Peculiarities of viruses Herpesviridae family persistence in patients with non-alcoholic fatty liver disease who had been exposed to the factors of Chornobyl NPP accident.
Structure of comorbid diseases in patients with non-alcoholic fatty liver disease, exposed to ionizing radiation as a result of the Chornobyl NPP accident.
THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION.
Fibromyalgia
Serum nucleotide pyrophosphohydrolase activity; elevated levels in osteoarthritis, calcium pyrophosphate crystal deposition disease, scleroderma, and fibromyalgia.
Fibrosarcoma
Cloning of MafG homologue from the rat brain by differential display and its expression after hypercapnic stimulation.
Glaucoma
Radiation induced violations of blood circulation in the ciliary body and changes of the anterior chamber angle in the pathogenesis of glaucoma in clean up workers of the Chornobyl NPP accident and residents of contaminated areas.
Glioblastoma
Stem cell characteristics in glioblastoma are maintained by the ecto-nucleotidase E-NPP1.
Glioma
An ecto-nucleotide pyrophosphatase is one of the main enzymes involved in the extracellular metabolism of ATP in rat C6 glioma.
Hematologic Diseases
Rationale treatment and preventive measures for correction of bone structure in children with acute leukemia, exposed to ionizing radiation due to the Chornobyl accident.
Hematologic Neoplasms
Inosine triphosphate pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defects.
Hepatitis
The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.
Hepatitis C
Absence of interferon-? 4 enhances spontaneous clearance of acute hepatitis C virus genotypes 1-3 infection.
Association between inosine triphosphatase rs1127354 polymorphisms and ribavirin-induced anaemia and outcome in hepatitis C virus-infected patients: A meta-analysis.
Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype.
High Prevalence of ITPA Alleles Associated with Ribavirin-Induced Hemolytic Anemia Among Mexican Population.
Impact of inosine triphosphatase gene variants on the risk of anemia in HIV/hepatitis C virus-coinfected patients treated for chronic hepatitis C.
Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR.
Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus.
Inosine triphosphate pyrophosphohydrolase activity: more accurate predictor for ribavirin-induced anemia in hepatitis C infected patients than ITPA genotype.
Interleukin28B and inosine triphosphatase help to personalize hepatitis C treatment.
ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
Pharmacogenetics of hepatitis C.
Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.
Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens.
Relationship between ITPA polymorphisms and hemolytic anemia in HCV-infected patients after ribavirin-based therapy: a meta-analysis.
Role of genetic polymorphisms in hepatitis C virus chronic infection.
The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.
Translating pharmacogenetics into clinical practice: interleukin (IL)28B and inosine triphosphatase (ITPA) polymophisms in hepatitis C virus (HCV) infection.
Variant Inosine Triphosphatase Phenotypes Are Associated With Increased Ribavirin Triphosphate Levels.
Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.
Hepatitis C, Chronic
A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms.
Allelic inhibition of displacement activity: a simplified one tube allele-specific PCR for evaluation of ITPA polymorphisms.
An automated rapid detection system using the quenching probe method for detecting interleukin 28B and inosine triphosphatase single nucleotide polymorphisms in chronic hepatitis C.
An index to predict ribavirin-induced anemia in asian patients with chronic genotype 1 hepatitis C.
Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.
Association of ITPA gene variation and serum ribavirin concentration with a decline in blood cell concentrations during pegylated interferon-alpha plus ribavirin therapy for chronic hepatitis C.
Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype.
Impact of inosine triphosphatase gene variants on the risk of anemia in HIV/hepatitis C virus-coinfected patients treated for chronic hepatitis C.
Induction of inosine triphosphatase activity during ribavirin treatment for chronic hepatitis C.
Inosine triphosphatase allele frequency and association with ribavirin-induced anaemia in Brazilian patients receiving antiviral therapy for chronic hepatitis C.
Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy.
Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function.
Inosine triphosphate pyrophosphatase polymorphisms are predictors of anemia in Chinese patients with chronic hepatitis C during therapy with ribavirin and interferon.
ITPA gene polymorphism (94C>A) effects on ribavirin-induced anemia during therapy in Egyptian patients with chronic hepatitis C.
ITPA gene variant may protect against anemia induced during pegylated interferon alfa and ribavirin combination treatment in Ukrainian patients with chronic hepatitis C.
ITPA gene variant protects against anemia induced by pegylated interferon-? and ribavirin therapy for Japanese patients with chronic hepatitis C.
ITPA Genotypes Predict Anemia but Do Not Affect Virological Response with Interferon-Free Faldaprevir, Deleobuvir, and Ribavirin for HCV Infection.
ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.
ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection.
Polymorphism of the inosine triphosphate pyrophosphatase gene predicts ribavirin-induced anemia in chronic hepatitis C patients.
Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.
Rapidity and Severity of Hemoglobin Decreasing Associated with Erythrocyte Inosine Triphosphatase Activity and ATP Concentration during Chronic Hepatitis C Treatment.
Role of IL-28B and inosine triphosphatase polymorphisms in efficacy and safety of Peg-Interferon and ribavirin in chronic hepatitis C compensated cirrhosis with and without oesophageal varices.
Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection.
Role of ITPA and IL28B variants in the management of chronic hepatitis C treatment.
Roles of ITPA and IL28B genotypes in chronic hepatitis C patients treated with peginterferon plus ribavirin.
The impact of an inosine triphosphate pyrophosphatase genotype on bilirubin increase in chronic hepatitis C patients treated with simeprevir, pegylated interferon plus ribavirin.
The impact of inosine triphosphatase variants on hemoglobin level and sustained virologic response of chronic hepatitis C in korean.
The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.
The role of ITPA and ribavirin transporter genes polymorphisms in prediction of ribavirin-induced anaemia in chronic hepatitis C Egyptian patients.
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction.
Herpes Simplex
Myastenia and small doses of ionizing radiation: experience of successful use of rituximab for treatment of an irradiated with myasthenia gravis.
Peculiarities of viruses Herpesviridae family persistence in patients with non-alcoholic fatty liver disease who had been exposed to the factors of Chornobyl NPP accident.
Hyperalgesia
5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain.
Abnormal activation of complement C3 in the spinal dorsal horn is closely associated with progression of neuropathic pain.
The role of the GABA-A receptor of the adjacent intact dorsal root ganglion neurons in rats with neuropathic pain.
Hyperglycemia
Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice.
THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION.
Hyperostosis
Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells.
Hypersensitivity
A Case of Erythritol Allergy Studied by Basophil Histamine Release and CD203c Expression In Vitro in Addition to a Challenge Test In Vivo.
Allergenicity suppression of tropomyosin from Exopalaemon modestus by glycation with saccharides of different molecular sizes.
Basophil Activation Experiments in Immediate Drug Hypersensitivity: More Than a Diagnostic Aid.
Basophil Activation Test Based on CD203c Expression in the Diagnosis of Fish Allergy.
CD203c in patients with cystic fibrosis and allergy to Aspergillus fumigatus.
CD203c-based basophil activation test in allergy diagnosis: Characteristics and differences to CD63 upregulation.
Clinical Utility of Basophil CD203c as a Biomarker for Predicting the Timing of Hypersensitivity Reaction in Carboplatin Rechallenge: Three Case Reports.
Comparison of Basophil Activation Test and Skin Testing Performances in NMBA Allergy.
Comparison of basophil activation tests using CD63 or CD203c expression in patients with insect venom allergy.
Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
Diagnostic Tests Based on Human Basophils: More Potentials and Perspectives than Pitfalls.
Diagnostic tests based on human basophils: more potentials and perspectives than pitfalls. II. Technical issues.
Differential GABAergic disinhibition during the development of painful peripheral neuropathy.
Evaluation of Basophil CD203c as a Predictor of Carboplatin-Related Hypersensitivity Reaction in Patients with Gynecologic Cancer.
Expression of CD203c on basophils as a marker of immunoglobulin E-mediated l-asparaginase allergy.
Flow cytometry for basophil activation markers: the measurement of CD203c up-regulation is as reliable as CD63 expression in the diagnosis of cat allergy.
For allergy diagnostic flow cytometry, detection of CD203c instead of CD63 is not at all an improvement in other hands.
HDAC2, but not HDAC1, regulates Kv1.2 expression to mediate neuropathic pain in CCI rats.
Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals.
In Vitro Diagnosis of Immediate Drug Hypersensitivity Anno 2017: Potentials and Limitations.
Individual hymenoptera venom compounds induce upregulation of the basophil activation marker ectonucleotide pyrophosphatase/phosphodiesterase 3 (CD203c) in sensitized patients.
In Vitro Diagnosis of Immediate Drug Hypersensitivity During Anesthesia: A Review of the Literature.
Loxoprofen sodium induces the production of complement C5a in human serum.
Marked improvement of the basophil activation test by detecting CD203c instead of CD63.
Peripheral basophil reactivity, CD203c expression by Cryj1 stimulation, is useful for diagnosing seasonal allergic rhinitis by Japanese cedar pollen.
Recombinant allergens promote expression of CD203c on basophils in sensitized individuals.
The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis.
The Contribution of the Basophil Activation Test to the Diagnosis of Hypersensitivity Reactions to Oxaliplatin.
Updates on the surface antigens of basophils: CD16 on basophils of patients with respiratory or insect venom allergy and the rejection of CD203c and CD63 externalization decoupling by bisindolylmaleimides.
Hypertension
Possible role of new pressor protein in hypertensive anephric hemodialysis patients.
Relationship between Stroke Events during Pachinko Play and Prognosis.
Role of bradykinin B2-receptor in the sympathoadrenal effects of 'new pressor protein' related to human blood coagulation factor XII fragment.
The effects of two types of renin-angiotensin system inhibitors on the hypertension induced by new pressor protein associated with beta-factor XIIa in rats.
THE EXPERTISE OF THE CAUSAL RELATIONSHIP BETWEEN THE DEVELOPMENT OF ARTERIAL HYPERTENSION WITH PARTICIPATION IN WORKS FOR LIQUIDATION OF THE CONSEQUENCES OF CHORNOBYL NPP ACCIDENT IN REMOTE POSTACCIDENTAL PERIOD.
Hypophosphatasia
Normal activity of nucleoside triphosphate pyrophosphatase in alkaline phosphatase-deficient fibroblasts from patients with infantile hypophosphatasia.
Immune System Diseases
ITPA Activity in Children Treated by Azathioprine: Relationship to the Occurrence of Adverse Drug Reactions and Inflammatory Response.
Infections
A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms.
Absence of interferon-? 4 enhances spontaneous clearance of acute hepatitis C virus genotypes 1-3 infection.
Allelic inhibition of displacement activity: a simplified one tube allele-specific PCR for evaluation of ITPA polymorphisms.
Cassava brown streak virus Ham1 protein hydrolyses mutagenic nucleotides and is a necrosis determinant.
Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Erythrocyte Inosine triphosphatase activity: A potential biomarker for adverse events during combination antiretroviral therapy for HIV.
Flavin metabolism during respiratory infection in mice.
High Prevalence of ITPA Alleles Associated with Ribavirin-Induced Hemolytic Anemia Among Mexican Population.
Individualization of chronic hepatitis C treatment according to the host characteristics.
Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function.
Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus.
Interleukin28B and inosine triphosphatase help to personalize hepatitis C treatment.
ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.
ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection.
Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection.
Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.
Role of postnatal penicillin prophylaxis in prevention of neonatal group B streptococcus infection.
Tailor-made therapy for viral hepatitis: recent advances.
The interactive effects of Eimeria acervulina infection and phytase for broiler chicks.
Translating pharmacogenetics into clinical practice: interleukin (IL)28B and inosine triphosphatase (ITPA) polymophisms in hepatitis C virus (HCV) infection.
Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.
[Genetic polymorphisms as predictors of response to antiviral treatment in chronic hepatitis C virus infection].
Infertility
[Occupational exposure and the reproductive health of man--personnel of the producing department of Smolensk NPP].
Inflammatory Bowel Diseases
A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs.
Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases.
Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease.
Correlation of genotypes for thiopurine methyltransferase and inosine triphosphate pyrophosphatase with long-term clinical outcomes in Korean patients with inflammatory bowel diseases during treatment with thiopurine drugs.
Meta-analysis: Inosine triphosphate pyrophosphatase polymorphisms and thiopurine toxicity in the treatment of inflammatory bowel disease.
Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.
Influenza, Human
Estimated Human and Economic Burden of Four Major Adult Vaccine-Preventable Diseases in the United States, 2013.
Highly increased levels of IgE antibodies to vaccine components in children with influenza vaccine-associated anaphylaxis.
Induction of primary anti-viral cytotoxic T cells by in vitro stimulation with short synthetic peptide and interleukin-7.
Transfer of CD8+ T cells into SCID mice and activation of memory virus-specific cytotoxic T cells.
Insulin Resistance
Cognitive deficits associated with a high-fat diet and insulin resistance are potentiated by overexpression of Ecto-nucleotide pyrophosphatase phosphodiesterase-1.
Evaluation of the PC-1 K121Q and G2906C variants as independent risk factors for ischaemic stroke.
Expression of membrane-bound NPP-type ecto-phosphodiesterases in rat podocytes cultured at normal and high glucose concentrations.
Mechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors.
Joint Diseases
Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs.
Synovial fluid inorganic pyrophosphate concentration and nucleotide pyrophosphohydrolase activity in basic calcium phosphate deposition arthropathy and Milwaukee shoulder syndrome.
Synovial fluid pyrophosphate and nucleoside triphosphate pyrophosphatase: comparison between normal and diseased and between inflamed and non-inflamed joints.
Joint Instability
FEATURES OF CLINICAL SYMPTOMS AND SIGNS, HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN CHILDREN WITH JOINT HYPERMOBILITY IN A LATE PERIOD UPON THE CHORNOBYL NPP ACCIDENT.
Leukemia
A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs.
Acute leukemias in children from the city of Kiev and Kiev region after the Chernobyl NPP catastrophe.
Basophil-lineage commitment in acute promyelocytic leukemia predicts for severe bleeding after starting therapy.
Cancer incidence in the vicinity of Finnish nuclear power plants: an emphasis on childhood leukemia.
CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking.
EFFECT OF SOMEUNFAVORABLE FACTORS OF ENVIRONMENT ON THE SURVIVAL OF CHILDREN WITH ACUTE LEUKEMIA IN A LONG6TERM PERIOD AFTER ACCIDENT ON THE CHORNOBYL NPP.
Patterns of hematological malignancies in Chernobyl clean-up workers (1996-2005).
Rationale treatment and preventive measures for correction of bone structure in children with acute leukemia, exposed to ionizing radiation due to the Chornobyl accident.
[Periferal blood subpopulation and apoptosis indices in the treatment of chronic myelogenous leukemia with Imatinib]
Leukemia, Lymphocytic, Chronic, B-Cell
Chronic lymphocytic leukemia patients exposed to ionizing radiation due to the Chernobyl NPP accident--with focus on immunoglobulin heavy chain gene analysis.
MYC copy number and mRNA expression in chronic lymphocytic leukemia patients exposed to ionizing radiation due to the Chornobyl NPP accident.
NOTCH1 mutations in chronic lymphocytic leukemia patients sufferers of Chornobyl NPP accident.
THE SPECTRUM OF TP53, SF3B1, AND NOTCH1 MUTATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS EXPOSED TO IONIZING RADIATION DUE TO THE CHORNOBYL NPP ACCIDENT.
Leukemia, Mast-Cell
CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
The efficiency of tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia exposed to ionizing radiation due to the Chornobyl nuclear power plant accident.
Leukemia, Promyelocytic, Acute
Basophil-lineage commitment in acute promyelocytic leukemia predicts for severe bleeding after starting therapy.
Leukopenia
Influences of Thiopurine Methyltransferase Genotype and Activity on Thiopurine-induced Leukopenia in Korean Patients With Inflammatory Bowel Disease: A Retrospective Cohort Study.
Liver Cirrhosis
RETROSPECTIVE ASSESSMENT OF CLINICAL-MORPHOLOGICAL CHANGES OF THE HEPATOBILIARY SYSTEM IN LIVER CIRRHOSIS OF THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS.
The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.
Liver Diseases
Impact of IL28B, ITPA and PNPLA3 genetic variants on therapeutic outcome and progression of hepatitis C virus infection.
Peculiarities of viruses Herpesviridae family persistence in patients with non-alcoholic fatty liver disease who had been exposed to the factors of Chornobyl NPP accident.
Peculiarity of prooxidant-antioxidant balance indicators in patients with nonalcoholic fatty liver disease who have been exposed to ionizing radiation due to the Chornobyl NPP accident.
Structure of comorbid diseases in patients with non-alcoholic fatty liver disease, exposed to ionizing radiation as a result of the Chornobyl NPP accident.
Lung Diseases, Obstructive
?HRONIC OBSTRUCTIVE PULMONARY DISEASE IN THE CLEAN-UP WORKERS OF CHORNOBYL NPP ACCIDENT IN A REMOTE POST6ACCIDENT PERIOD (CLINICAL STUDY).
Lupus Erythematosus, Systemic
Inosine triphosphate pyrophosphatase 94C> A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine.
Pro32Thr polymorphism of inosine triphosphate pyrophosphatase gene predicts efficacy of low-dose azathioprine for patients with systemic lupus erythematosus.
Lymphocytosis
Lymphocytosis in children after the Chornobyl NPP accident.
Lymphoma, Non-Hodgkin
Leukaemia in young children in the vicinity of British nuclear power plants: a case-control study.
Macular Degeneration
The risk of macular degeneration development in persons antenatally irradiated as a result of Chornobyl NPP accident.
Malaria
Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable.
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum.
Neuropsychiatric problems in 2,500 long-term young travelers to the tropics.
Mastocytosis
Basophil Activation Test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy.
Mastocytosis, Systemic
CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking.
In vitro and in vivo efficacy of an anti-CD203c conjugated antibody (AGS-16C3F) in mouse models of advanced systemic mastocytosis.
Melanoma
Dabrafenib plus trametinib is effective in the treatment of BRAF V600-mutated metastatic melanoma patients: analysis of patients from the dabrafenib plus trametinib Named Patient Program (DESCRIBE II).
The antibody-drug conjugate target landscape across a broad range of tumour types.
Mesothelioma
Mesothelioma mortality within two radiation monitored occupational cohorts.
Milk Hypersensitivity
Basophil activation marker CD203c is useful in the diagnosis of hen's egg and cow's milk allergies in children.
Basophil activation test based on the expression of CD203c in the diagnostics of cow milk allergy in children.
Mucositis
Assessment of Peri-Implant Soft Tissues Conditions around Short and Ultra-Short Implant-Supported Single Crowns: A 3-Year Retrospective Study on Periodontally Healthy Patients and Patients with a History of Periodontal Disease.
Multiple Myeloma
EFFICIENCY OF BONE MARROW PRECURSOR CELL COLONY-FORMING AS A PREDICTOR OF DISEASE COURSE IN PLASMA CELL MYELOMA PATIENTS WITH A HISTORY OF RADIATION EXPOSURE.
MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma.
Muscle Weakness
Paralytic vs. "nonparalytic" polio: distinction without a difference?
Myasthenia Gravis
Myastenia and small doses of ionizing radiation: experience of successful use of rituximab for treatment of an irradiated with myasthenia gravis.
Myocardial Infarction
Analysis of some risk factors for myocardial infarction in a cohort of the Chornobyl clean-up workers (according to the data of Clinical and Epidemiological Registry).
Nasal Obstruction
Role of nasal problems on positional and nonpositional obstructive sleep apnea.
Neoplasm Metastasis
Ectonucleotide pyrophosphatase/phosphodiesterase (E-NPP) and adenosine deaminase (ADA) activities in prostate cancer patients: Influence of Gleason score, treatment and bone metastasis.
Effectiveness and safety of aflibercept for metastatic colorectal cancer: retrospective review within an early access program in Spain.
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family.
Neoplasms
AGS16F Is a Novel Antibody Drug Conjugate Directed against ENPP3 for the Treatment of Renal Cell Carcinoma.
Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome.
Can a trained non-physician provider perform transrectal ultrasound-guided prostatic biopsies as effectively as an experienced urologist?
Characterization of a new plasma membrane-associated ecto-5'-phosphodiesterase/nucleotide-pyrophosphatase from rat hepatocarcinoma AS-30D cells.
Childhood cancer and nuclear power plants in Switzerland: a census-based cohort study.
Collagen alpha1(XI) in normal and malignant breast tissue.
Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors.
Differential expression of nucleotide pyrophosphatase/phosphodiesterases by Walker 256 mammary cancer cells in solid tumors and malignant ascites.
Ectonucleotidase expression profile and activity in human cervical cancer cell lines.
Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis.
Epidemiological evidence of childhood leukaemia around nuclear power plants.
Evaluation of Basophil CD203c as a Predictor of Carboplatin-Related Hypersensitivity Reaction in Patients with Gynecologic Cancer.
Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia.
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases.
Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-I beta/B10/gp130RB13-6) in human colon carcinoma.
Global and local cancer risks after the Fukushima Nuclear Power Plant accident as seen from Chernobyl: a modeling study for radiocaesium ((134)Cs &(137)Cs).
Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase.
Identification of two novel tumor-associated antigens recognized by HLA-B46-restricted cytotoxic T lymphocytes.
Increased cancer risk in male hunters compared to the general male population in Northern Sweden after the Chernobyl Nuclear Power Plant accident?
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia.
Leukaemia in young children in the vicinity of British nuclear power plants: a case-control study.
Long-term outcome of transpupillary thermotherapy as primary treatment of selected choroidal melanoma.
Naphthalimide-phenanthroimidazole incorporated new fluorescent sensor for "turn-on" Cu2+ detection in living cancer cells.
Patterns of hematological malignancies in Chernobyl clean-up workers (1996-2005).
Perceived environmental and health risks of nuclear energy in Taiwan after Fukushima nuclear disaster.
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family.
Radiation and epidemiological analysis for solid cancer incidence among nuclear workers who participated in recovery operations following the accident at the Chernobyl NPP.
Risk perception, trust, and factors related to a planned new nuclear power plant in Taiwan after the 2011 Fukushima disaster.
Selective Induction of Tumor Cell Apoptosis by a Novel P450-mediated Reactive Oxygen Species (ROS) Inducer Methyl 3-(4-Nitrophenyl) Propiolate.
Structural basis of allotypes of ecto-nucleotide pyrophosphatase/phosphodiesterase (plasma cell membrane glycoprotein PC-1) in the mouse and rat, and analysis of allele-specific xenogeneic antibodies.
Study Protocol for radiation exposure and cancer risk assessment- The Taiwan Nuclear Power Plants and Epidemiology Cohort Study (TNPECS).
Synthesis, biological evaluation, and docking studies of novel pyrrolo[2,3-b]pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents.
The antibody-drug conjugate target landscape across a broad range of tumour types.
The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases.
The Maf transcription factors: regulators of differentiation.
Therapeutic impact of orally administered cannabinoid oil extracts in an experimental autoimmune encephalomyelitis animal model of multiple sclerosis.
Vascular markers for murine tumours.
[Current treatment approaches and prospects in thyroid cancer]
[The immunocorrection with Aerosil-350 of the natural resistance of mice found under conditions of an elevated radiation background]
[The mechanism of the immunomodulating action of Béres Drops Plus]
Neuralgia
5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain.
A pilot study of neuromuscular electrical stimulation for neuropathic pain caused by spinal cord injury.
HDAC2, but not HDAC1, regulates Kv1.2 expression to mediate neuropathic pain in CCI rats.
Incidence and predictors of neuropathic pain following breast surgery.
Normalizing JMJD6 Expression in Rat Spinal Dorsal Horn Alleviates Hyperalgesia Following Chronic Constriction Injury.
Neuroblastoma
Natural Compounds and their Analogues as Potent Antidotes against the Most Poisonous Bacterial toxin.
Neutropenia
A randomized, placebo-controlled trial of granulocyte colony-stimulating factor administration to newborn infants with neutropenia and clinical signs of early-onset sepsis.
Neutropenia related to an azathioprine metabolic disorder induced by an inosine triphosphate pyrophosphohydrolase (ITPA) gene mutation in a patient with PR3-ANCA-positive microscopic polyangiitis?.
Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine.
Non-alcoholic Fatty Liver Disease
Comparative characteristics of hepatoprotectors used for the treatment of non alcoholic steatohepatitis associated with herpesvirus infection in sufferers of the Chornobyl accident.
Peculiarities of viruses Herpesviridae family persistence in patients with non-alcoholic fatty liver disease who had been exposed to the factors of Chornobyl NPP accident.
Peculiarity of prooxidant-antioxidant balance indicators in patients with nonalcoholic fatty liver disease who have been exposed to ionizing radiation due to the Chornobyl NPP accident.
Structure of comorbid diseases in patients with non-alcoholic fatty liver disease, exposed to ionizing radiation as a result of the Chornobyl NPP accident.
nucleotide diphosphatase deficiency
A disease spectrum for ITPA variation: advances in biochemical and clinical research.
A Japanese case with inosine triphosphate pyrophosphohydrolase deficiency attributable to an enzymatic defect in white blood cells.
Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).
Allele frequency of inosine triphosphate pyrophosphatase gene polymorphisms in a Japanese population.
Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients.
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
DNA polymorphisms in ITPA including basis of inosine triphosphatase deficiency.
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population.
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.
Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.
Hy-Line W-36 and Hy-Line W-98 laying hens respond similarly to dietary phosphorus levels.
Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy.
Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR.
Inosine triphosphate pyrophosphohydrolase deficiency in a kindred with adenosine deaminase deficiency.
Interrelationship between environmental temperature and dietary nonphytate phosphorus in chicks.
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.
ITPA Genotype Protects Against Anemia During Peginterferon And Ribavirin Therapy But Does Not Influence Virological Response.
ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection.
ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy.
Mutation in the ITPA gene predicts intolerance to azathioprine.
PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification.
Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease.
Relationship between ITPA polymorphisms and hemolytic anemia in HCV-infected patients after ribavirin-based therapy: a meta-analysis.
Roles of ITPA and IL28B genotypes in chronic Hepatitis C patients treated with peginterferon plus ribavirin in Tunisian population.
The effect of ITPA polymorphisms on the enzyme kinetic properties of human erythrocyte inosine triphosphatase toward its substrates ITP and 6-Thio-ITP.
The effect of virginiamycin in diets with adequate or reduced dietary calcium or nonphytate phosphorus for broilers.
The ITPA and C20orf194 Polymorphisms and Hematological Changes During Treatment With Pegylated-Interferon Plus Ribavirin in Patients With Chronic Hepatitis C.
The ITPA c.94C>A and g.IVS2+21A>C sequence variants contribute to missplicing of the ITPA gene.
Typing TPMT and ITPase to detect azathioprine toxicity.
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction.
[Genetic polymorphisms as predictors of response to antiviral treatment in chronic hepatitis C virus infection].
Nut Hypersensitivity
Basophil CD203c Levels Are Increased at Baseline and Can Be Used to Monitor Omalizumab Treatment in Subjects with Nut Allergy.
Obesity
Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice.
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Serum content of total adipionectin in the ChNPP accident clean up workers of the «iodine period» suffering from type 2 diabetes mellitus (literature review and research data).
Occupational Diseases
Clinical aspects of the health disturbances in Chernobyl Nuclear Power Plant accident clean-up workers (liquidators) from Latvia.
Osteoarthritis
A unique ectonucleotide pyrophosphohydrolase associated with porcine chondrocyte-derived vesicles.
Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors.
Serum nucleotide pyrophosphohydrolase activity; elevated levels in osteoarthritis, calcium pyrophosphate crystal deposition disease, scleroderma, and fibromyalgia.
Synovial fluid pyrophosphate and nucleoside triphosphate pyrophosphatase: comparison between normal and diseased and between inflamed and non-inflamed joints.
The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles.
Osteosarcoma
Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta.
Expression of the nucleoside triphosphate pyrophosphohydrolase PC-1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast-like osteosarcoma cells.
The antibody-drug conjugate target landscape across a broad range of tumour types.
Ovarian Cysts
Analysis of the ectoenzymes ADA, ALP, ENPP1, and ENPP3, in the contents of ovarian endometriomas as candidate biomarkers of endometriosis.
Ovarian Neoplasms
[The incidence and clinical genealogical analysis of ovarian cancer in the Kharkiv region]
Overweight
Serum content of total adipionectin in the ChNPP accident clean up workers of the «iodine period» suffering from type 2 diabetes mellitus (literature review and research data).
Pancreatitis
Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine.
Paralysis
Abducens internuclear neurons and their role in conjugate horizontal gaze.
Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy.
Paresis
Abducens internuclear neurons and their role in conjugate horizontal gaze.
Parkinson Disease
Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy.
Parkinsonian Disorders
Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy.
Peanut Hypersensitivity
Basophil activation tests for the diagnosis of food allergy in children.
Basophil CD203c Levels Are Increased at Baseline and Can Be Used to Monitor Omalizumab Treatment in Subjects with Nut Allergy.
Peri-Implantitis
Assessment of Peri-Implant Soft Tissues Conditions around Short and Ultra-Short Implant-Supported Single Crowns: A 3-Year Retrospective Study on Periodontally Healthy Patients and Patients with a History of Periodontal Disease.
Peripheral Nerve Injuries
GABA(A) receptor modulation in dorsal root ganglia in vivo affects chronic pain after nerve injury.
iTRAQ-based proteomics profiling of Schwann cells before and after peripheral nerve injury.
Persistent Infection
Comparative characteristics of hepatoprotectors used for the treatment of non alcoholic steatohepatitis associated with herpesvirus infection in sufferers of the Chornobyl accident.
Plagiocephaly
Impact of an advanced practice provider-directed plagiocephaly clinic for neurosurgical practices.
Plasmacytoma
Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1.
Modulation of nucleotide pyrophosphatase in plasmacytoma cells.
Poliomyelitis
Paralytic vs. "nonparalytic" polio: distinction without a difference?
Pre-Eclampsia
Plasma Cell Membrane Glycoprotein-1 K121Q Polymorphism in Preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Comparative pharmacogenetic analysis of risk polymorphisms in Caucasian and Vietnamese children with acute lymphoblastic leukemia: prediction of therapeutic outcome?
Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia.
Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia.
Impact of age, gender and haplotypes of thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) genes on 6-mercaptopurine toxicity in children with acute lymphoblastic leukemia.
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.
Role of TPMT and ITPA variants in mercaptopurine disposition.
State of erythroid, granulocyte and platelet branches of hematopoiesis on stages of chemotherapy in children with acute lymphoblastic leukemia, who were exposed to ionizing radiation after the Chornobyl NPP accident.
The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children.
The Role of TPMT, ITPA, and NUDT15 Variants during Mercaptopurine Treatment of Swedish Pediatric Patients with Acute Lymphoblastic Leukemia.
Prostatic Neoplasms
Can a trained non-physician provider perform transrectal ultrasound-guided prostatic biopsies as effectively as an experienced urologist?
First results of endocavity evaluation of the microvascularization of malignant prostate tumors using contrast enhanced ultrasound (CEUS) including perfusion analysis: First results.
Prurigo
Basophil recruitment and activation in inflammatory skin diseases.
Pulmonary Disease, Chronic Obstructive
Late effects of ionizing radiation on functional status of bronchopulmonary system in COPD patients among the clean-up workers of the Chornobyl NPP accident.
Optimization of chronic obstructive pulmonary disease treatment in clean-up workers of the Chornobyl NPP accident in the remote period after irradiation.
Retinal Hemorrhage
Association of perpetrator relationship to abusive head trauma clinical outcomes.
Rett Syndrome
Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome.
Rheumatic Diseases
Serum nucleotide pyrophosphohydrolase activity; elevated levels in osteoarthritis, calcium pyrophosphate crystal deposition disease, scleroderma, and fibromyalgia.
Rhinitis, Allergic
Basophil biomarkers as useful predictors for sublingual immunotherapy in allergic rhinitis.
Peripheral basophil reactivity, CD203c expression by Cryj1 stimulation, is useful for diagnosing seasonal allergic rhinitis by Japanese cedar pollen.
Rhinitis, Allergic, Seasonal
Allergen-induced basophil CD203c expression as a biomarker for rush immunotherapy in patients with Japanese cedar pollinosis.
Allergen-specific basophil reactivity exhibits daily variations in seasonal allergic rhinitis.
Biomarkers for Allergen Immunotherapy in Cedar Pollinosis.
Peripheral basophil reactivity, CD203c expression by Cryj1 stimulation, is useful for diagnosing seasonal allergic rhinitis by Japanese cedar pollen.
Reliability of basophil activation test using CD203c expression in diagnosis of pollen allergy.
Rotator Cuff Tear Arthropathy
Synovial fluid inorganic pyrophosphate concentration and nucleotide pyrophosphohydrolase activity in basic calcium phosphate deposition arthropathy and Milwaukee shoulder syndrome.
Sarcoma
Sheep gene mapping: additional DNA markers included (CASB, CASK, LALBA, IGF-1 and AMH).
Seminoma
Ectonucleoside triphosphate diphosphohydrolase 6 expression in testis and testicular cancer and its implication in cisplatin resistance.
Sepsis
A randomized, placebo-controlled trial of granulocyte colony-stimulating factor administration to newborn infants with neutropenia and clinical signs of early-onset sepsis.
Role of postnatal penicillin prophylaxis in prevention of neonatal group B streptococcus infection.
Sleep Apnea Syndromes
Standardized framework to report on the role of sleeping position in sleep apnea patients.
Spinal Cord Injuries
A pilot study of neuromuscular electrical stimulation for neuropathic pain caused by spinal cord injury.
Squamous Cell Carcinoma of Head and Neck
Plasmacytoid dendritic cell subpopulations in head and neck squamous cell carcinoma.
Stillbirth
Birth defects in the vicinity of nuclear power plants in Germany.
Stroke
Neuropathic pain releasing calcitonin gene related peptide protects against stroke in rats.
Prothrombotic factors and the risk of acute onset non-cardioembolic stroke in young Asian Indians.
Supranuclear Palsy, Progressive
Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy.
Testicular Neoplasms
Ectonucleoside triphosphate diphosphohydrolase 6 expression in testis and testicular cancer and its implication in cisplatin resistance.
thiopurine s-methyltransferase deficiency
Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.
Thrombocytopenia
Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia.
Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine.
Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.
Severe thrombocytopenia in a patient with inosine triphosphatase (ITPA)-CC genotype caused by pegylated interferon (IFN)-?-2a with ribavirin therapy: a case report.
Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.
[The principles of and some experience with component therapy in acute radiation sickness]
Thrombophilia
Does recombinant factor VIIa, apart from overall hemostasis, regulate TAFI dependent fibrinolysis? In vitro analysis using overall hemostasis potential (OHP) assay.
Thyroid Neoplasms
Age and gender patterns of thyroid cancer incidence in Ukraine depending on thyroid radiation doses from radioactive iodine exposure after the Chornobyl NPP accident.
Age distribution of childhood thyroid cancer patients in Ukraine after Chernobyl and in Fukushima after the TEPCO-Fukushima Daiichi NPP accident.
Projecting thyroid cancer risk to the general public from radiation exposure following hypothetical severe nuclear accidents in Canada.
The cellular localization of autotaxin impacts on its biological functions in human thyroid carcinoma cells.
[Thyroid cancer: lessons of chernobyl and prognosis for Fukushima].
Transfusion Reaction
Anaphylactic transfusion reaction in homozygous haptoglobin deficiency detected by CD203c expression on basophils.
triphosphatase deficiency
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
Tuberculosis
Mycobacterial MazG is a novel NTP pyrophosphohydrolase involved in oxidative stress response.
The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Urticaria
Basophil recruitment and activation in inflammatory skin diseases.
Chronic urticaria sera increase basophil CD203c expression.
Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
Diagnostic utility of the basophil activation test in natto-induced hypersensitivity.
Improved Fc?RI-Mediated CD203c Basophil Responsiveness Reflects Rapid Responses to Omalizumab in Chronic Spontaneous Urticaria.
Increased level of basophil CD203c expression predicts severe chronic urticaria.
Varicose Veins
Role of IL-28B and inosine triphosphatase polymorphisms in efficacy and safety of Peg-Interferon and ribavirin in chronic hepatitis C compensated cirrhosis with and without oesophageal varices.
Vascular Calcification
Synthesis and computational studies of highly selective inhibitors of human recombinant tissue non-specific alkaline phosphatase (h-TNAP): A therapeutic target against vascular calcification.
Vascular Diseases
Evaluation of the PC-1 K121Q and G2906C variants as independent risk factors for ischaemic stroke.
Vesicular Stomatitis
Uncapping of viral messenger RNA by phosphodiesterase of fibroblast plasma membranes.
Wheat Hypersensitivity
Antigen-Induced Expression of CD203c on Basophils Predicts IgE-mediated Wheat Allergy.