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Reference on EC 3.6.1.5 - apyrase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Curdova, E.; Jechova, V.; Hostalek, Z.
Properties of apyrase and inorganic pyrophosphatase in Streptomyces aureofaciens
Folia Microbiol. (Praha)
27
159-166
1982
Kitasatospora aureofaciens, Kitasatospora aureofaciens RIA 57
Manually annotated by BRENDA team
Mancilla, M.; Valenzuela, M.A.; Anich, M.; Kettlun, A.M.; Jara, O.; Traverso-Cori, A.
Identification of an apyrase activating protein and of calmodulin in Solanum tuberosum
Phytochemistry
26
2471-2474
1987
Solanum tuberosum
-
Manually annotated by BRENDA team
Miura, Y.; Hirota, K.; Arai, Y.; Yagi, K.
Purification and partial characterization of adenosine diphosphatase activity in bovine aorta microsomes
Thromb. Res.
46
685-695
1987
Bos taurus
Manually annotated by BRENDA team
Sarkis, J.J.F.; Guimares, J.A.; Ribeiro, J.M.C.
Salivary apyrase of Rhodnius prolixus. Kinetics and purification
Biochem. J.
233
885-891
1986
Rhodnius prolixus
Manually annotated by BRENDA team
Beaudoin, A.R.; Vachereau, A.; Grondin, G.; St-Jean, P.; Rosenberg, M.D.; Strobel, R.
Microvesicular secretion, a mode of cell secretion associated with the presence of an ATP-diphosphohydrolase
FEBS Lett.
203
1-2
1986
Rattus norvegicus
Manually annotated by BRENDA team
Mancilla, M.; Kettlun, A.M.; Valenzuela, M.A.; Traverso-Cori, A.
Structural studies of two apyrases from Solanum tuberosum
Phytochemistry
23
1397-1400
1984
Solanum tuberosum
-
Manually annotated by BRENDA team
Haromy, T.P.; Knight, W.B.; Dunaway-Mariano, D.; Sundaralingam, M.
Investigation of structure, protonation, and reactivity of tetraamine(imidodiphosphato)cobalt(III), a substrate for potato apyrase
Biochemistry
22
5015-5021
1985
Solanum tuberosum
-
Manually annotated by BRENDA team
Knowles, A.F.; Isler, R.E.; Reece, J.F.
The common occurrence of ATP diphosphohydrolase in mammalian plasma membranes
Biochim. Biophys. Acta
731
88-96
1983
Canis lupus, Homo sapiens, Mus sp.
Manually annotated by BRENDA team
Laliberte, J.F.; Beaudoin, A.R.
Sequential hydrolysis of the gamma- and beta-phosphate groups of ATP by the ATP diphosphohydrolase from pig pancreas
Biochim. Biophys. Acta
742
9-15
1983
Sus scrofa
Manually annotated by BRENDA team
Kettlun, A.M.; Uribe, L.; Calvo, V.; Silva, S.; Rivera, J.; Mancilla, M.; Valenzuela, M.A.; Traverso-Cori, A.
Properties of two apyrases from Solanum tuberosum
Phytochemistry
21
551-558
1982
Solanum tuberosum
-
Manually annotated by BRENDA team
Vara, F.; Serrano, R.
Purification and characterization of a membrane-bound ATP diphosphohydrolase from Cicer arietinum (chick-pea) roots
Biochem. J.
197
637-643
1981
Cicer arietinum
Manually annotated by BRENDA team
Laliberte, J.F.; St.Jean, P.; Beaudoin, A.R.
Kinetic effects of Ca2+ and Mg2+ on ATP hydrolysis by the purified ATP diphosphohydrolase
J. Biol. Chem.
257
3869-3874
1982
Sus scrofa
Manually annotated by BRENDA team
Smith, J.J.B.; Cornish, R.A.; Wilkens, J.
Properties of a calcium-dependent apyrase in the saliva of the blood sucking bug, Rhodnius prolixus
Experientia
36
898-900
1980
Rhodnius prolixus
-
Manually annotated by BRENDA team
LeBel, D.; Poirier, G.G.; Phaneuf, S.; St-Jean, P.; Laliberte, J.F.; Beaudoin, A.R.
Characterization and purification of a calcium-sensitive ATP diphosphohydrolase from pig pancreas
J. Biol. Chem.
255
1227-1233
1980
Sus scrofa
Manually annotated by BRENDA team
Traverso-Cori, A.; Traverso, S.; Reyes, H.
Different molecular forms of potato apyrase
Arch. Biochem. Biophys.
137
133-142
1970
Solanum tuberosum
Manually annotated by BRENDA team
Tognoli, L.; Marre E.
Purification and characterization of a divalent cation-activated ATP-ADPase from pea stem microsomes
Biochim. Biophys. Acta
642
1-14
1981
Pisum sativum
Manually annotated by BRENDA team
Biederbick, A.; Kosan, C.; Kunz, J.; Elsaesser, H.P.
First apyrase splice variants have different enzymatic properties
J. Biol. Chem.
275
19018-19024
2000
Homo sapiens
Manually annotated by BRENDA team
Lemmens, R.; Kupers, L.; Sevigny, J.; Beaudoin, A.R.; Grondin, G.; Kittel, A.; Waelkens, E.; Vanduffel, L.
Purification, characterization, and localisation of an ATP diphosphohydrolase in porcine kidney
Am. J. Physiol.
278
978-988
2000
Sus scrofa
-
Manually annotated by BRENDA team
Sevigny, J.; Robson, S.C.; Waelkens, E.; Csizmadia, E.; Smith, R.N.; Lemmens, R.
Identification and characterization of a novel hepatic canalicular ATP diphosphohydrolase
J. Biol. Chem.
275
5640-5647
2000
Sus scrofa
Manually annotated by BRENDA team
Lemmens, R.; Vanduffel, L.; Kittel, A.; Beaudoin, A.R.; Benrezzak, O.; Sevigny, J.
Distribution, cloning, and characterisation of porcine nucleoside triphosphate disphosphohydrolase-1
Eur. J. Biochem.
267
4106-4114
2000
Sus scrofa (Q9MYU4), Sus scrofa
Manually annotated by BRENDA team
Heine, P.; Braun, N.; Heilbronn, A.; Zimmermann, H.
Functional characterization of rat ecto-ATPase and ecto-ATP diphosphohydrolase after heterologous expression in CHO cells
Eur. J. Biochem.
262
102-107
1999
Rattus norvegicus
Manually annotated by BRENDA team
Shibata, K.; Morita, Y.; Stankovic, B.; Davies, E.
Apyrase from pea stems: Isolation, purification, characterization and identification of a NTPase from cytokeleton fraction of pea stem tissue
Plant Physiol. Biochem.
37
881-888
1999
Pisum sativum
-
Manually annotated by BRENDA team
Cheeseman, M.T.
Characterization of apyrase activity from the salivary glands of the cat flea Ctenocephalides felis
Insect Biochem. Mol. Biol.
28
1025-1030
1998
Ctenocephalides felis
Manually annotated by BRENDA team
Valenzuela, J.G.; Charlab, R.; Galperin, M.Y.; Ribeiro, J.M.C.
Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius
J. Biol. Chem.
273
30583-30590
1998
Cimex lectularius
Manually annotated by BRENDA team
Mans, B.J.; Gaspar, A.I.; Louw, A.I.; Neitz, A.W.H.
Purification and characterization of apyrase from the tick, Ornithodoros savignyi
Comp. Biochem. Physiol. B
120
617-624
1998
Ornithodoros savignyi
Manually annotated by BRENDA team
Sevigny, J.; Picher, M.; Grondin, G.; Beaudoin, A.R.
Purification and immunohistochemical localisation of the ATP diphosphohydrolase in bovine lungs
Am. J. Physiol.
272
939-950
1997
Bos taurus
-
Manually annotated by BRENDA team
Beaudoin, A.R; Sevigny, J.; Grondin, G.; Daoud, S.; Levesque, F.P.
Purification, characterization, and localisation of two ATP diphosphohydrolase isoforms in bovine heart
Am. J. Physiol.
273
673-681
1997
Bos taurus
-
Manually annotated by BRENDA team
De Oliveira, M.E.; Battastini, O.A.M.; Meirelles, M.N.; Moreira, M.C.; Dias, R.D.; Sarkis, J.J.
Characterization and localisation of an ATP diphosphohydrolase activity (EC 3.6.1.5) in sarcolemmal membrane from rat heart
Mol. Cell. Biochem.
170
115-123
1997
Rattus norvegicus
Manually annotated by BRENDA team
Kaczmarek, E.; Koziak, K.; Sevigny, J.; Siegel, J.B.; Anrather, J.; Beaudoin, A.R.; Bach, F.H.; Robson, S.C.
Identification and characterization of CD39/vascular ATP diphosphohydrolase
J. Biol. Chem.
271
33116-33122
1996
Bos taurus, Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Valenzuela, M.A; Ketttlun, A.M.; Sandoval, S.; Garcia, L.; Mancilla, M.; Neckelmann, G.; Chayet, L.; Alvarez, A.; Cuevas, F.; Collados, L.; Espinosa, V.; Traverso-Cori, A.; Bravo, I.; Acevedo, C.G.; Aranda, E.
Comparison of the biochemical properties, regulation and function of ATP diphosphohydrolase from human placenta and rat kidney
Braz. J. Med. Biol. Res.
29
589-597
1996
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Battastini, A.M.O.; Oliveira, E.M.; Moreira, C.M.; Bonan, C.D; Sarkis, J.J; Dias, R.D.
Solubilization and characterization of an ATP diphosphohydrolase (EC 3.6.1.5) from rat brain synaptic plasma membranes
Biochem. Mol. Biol. Int.
37
209-219
1995
Rattus norvegicus
Manually annotated by BRENDA team
Komoszynski, M.A.
Comparative studies of animal and plant apyrases (ATP diphosphohydrolase EC 3.6.1.5) with application of immunological techniques and various ATPase inhibitors
Comp. Biochem. Physiol. B
113
581-591
1996
Bos taurus, Hordeum vulgare, Lupinus luteus, Pisum sativum, Secale cereale, Solanum tuberosum, Triticosecale Wittmack, Triticum aestivum, Zea mays
Manually annotated by BRENDA team
Frassetto, S.S.; Dias, R.D.; Sarkis, J.J.
Inhibition and kinetic alterations by excess free ATP and ADP of the ATP disphosphohydrolase activity (EC 3.6.1.5) from rat blood platelets
Biochem. Mol. Biol. Int.
35
499-506
1995
Rattus norvegicus
Manually annotated by BRENDA team
Ziganshin, A.U.; Zigashina, L.E.; Bodin, P.; Bailey, D.; Burnstock, G.
Effect of P2-purinreceptor antagonist on ecto-nucleotidase activity of guinea-pig vas deferens cultured smooth muscle cells
Biochem. Mol. Biol. Int.
36
863-869
1995
Cavia porcellus
Manually annotated by BRENDA team
Kettlun, A.M.; Alvarez, A.; Quintar, R.; Valenzuela, M.A.; Collados, L.; Aranda, E.; Banda, A.; Chayet, L.; Chiong, M.; Mancilla, M.; Traverso-Cori, A.
Human placental ATP-diphosphohydrolase: biochemical characterization, regulation and function
Int. J. Biochem.
26
437-448
1994
Homo sapiens
Manually annotated by BRENDA team
Frassetto, S.S.; Dias, R.D.; Sarkis, J.J.
Characterization of an ATP diphosphohydrolase activity (apyrase EC 3.6.1.5) in rat blood platelets
Mol. Cell. Biochem.
129
47-55
1993
Rattus norvegicus
Manually annotated by BRENDA team
Cote, Y.P.; Quellet, S.; Beaudoin, A.R.
Kinetic properties of type-II ATP diphosphohydrolase from the tunica media of the bovine aorta
Biochim. Biophys. Acta
1160
246-250
1992
Bos taurus
Manually annotated by BRENDA team
Cote, Y.P.; Filep, J.G.; Battistini, B.; Gauvreau, J.; Sirois, P.; Beaudoin, A.R.
Characterization of ATP-diphosphohydrolase activities in the intima and media of bovine aorta: evidence for a regulatory role in platelet activation in vitro
Biochim. Biophys. Acta
1139
133-142
1992
Bos taurus
Manually annotated by BRENDA team
Guranowski, A.; Starzynska, E.; Rataj-Guranowska, M.; Sillero, M.A.G.
Purification of apyrase from yellow lupin cotyledons after extraction with perchloric acid
Protein Expr. Purif.
2
235-239
1991
Lupinus luteus
Manually annotated by BRENDA team
Ribeiro, J.M.C.; Vaughan, J.A.; Azad, A.F.
Characterization of the salivary apyrase activity of three rodent flea species
Comp. Biochem. Physiol. B
95
215-219
1990
Orchopeas howardi, Oropsylla bacchi, Xenopsylla cheopis
Manually annotated by BRENDA team
Fietto, J.L.R.; DeMarco, R.; Nascimento, I.P.; Castro, I.M.; Carvalho, T.M.U.; de Souza, W.; Bahia, M.T.; Alves, M.J.M.; Verjovski-Almeida, S.
Characterization and immunolocalization of an NTP diphosphohydrolase of Trypanosoma cruzi
Biochem. Biophys. Res. Commun.
316
454-460
2004
Trypanosoma cruzi (Q6QHT8)
Manually annotated by BRENDA team
Lavoie, E.G.; Kukulski, F.; Levesque, S.A.; Lecka, J.; Sevigny, J.
Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-3
Biochem. Pharmacol.
67
1917-1926
2004
Mus musculus (Q8BFW6), Mus musculus
Manually annotated by BRENDA team
Bigonnesse, F.; Levesque, S.A.; Kukulski, F.; Lecka, J.; Robson, S.C.; Fernandes, M.J.G.; Sevigny, J.
Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8
Biochemistry
43
5511-5519
2004
Mus musculus (Q8K0L2), Mus musculus
Manually annotated by BRENDA team
Demenis, M.A.; Furriel, R.P.M.; Leone, F.A.
Characterization of an ectonucleoside triphosphate diphosphohydrolase 1 activity in alkaline phosphatase-depleted rat osseous plate membranes: possible functional involvement in the calcification process
Biochim. Biophys. Acta
1646
216-225
2003
Rattus norvegicus
Manually annotated by BRENDA team
Sevigny, J.; Sundberg, C.; Braun, N.; Guckelberger, O.; Csizmadia, E.; Qawi, I.; Imai, M.; Zimmermann, H.; Robson, S.C.
Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation
Blood
99
2801-2809
2002
Mus musculus
Manually annotated by BRENDA team
Alves-Ferreira, M.; Dutra, P.M.; Lopes, A.H.; Ferreira-Pereira, A.; Scofano, H.M.; Meyer-Fernandes, J.R.
Magnesium-dependent ecto-ATP diphosphohydrolase activity in Herpetomonas muscarum muscarum
Curr. Microbiol.
47
265-271
2003
Herpetomonas muscarum
Manually annotated by BRENDA team
Heine, P.; Braun, N.; Sevigny, J.; Robson, S.C.; Servos, J.; Zimmermann, H.
The C-terminal cysteine-rich region dictates specific catalytic properties in chimeras of the ectonucleotidases NTPDase1 and NTPDase2
Eur. J. Biochem.
268
364-373
2001
Rattus norvegicus
Manually annotated by BRENDA team
Knowles, A.F.; Nagy, A.K.; Strobel, R.S.; Wu-Weis, M.
Purification, characterization, cloning, and expression of the chicken liver ecto-ATP-diphosphohydrolase
Eur. J. Biochem.
269
2373-2382
2002
Gallus gallus
Manually annotated by BRENDA team
Failer, B.U.; Aschrafi, A.; Schmalzing, G.; Zimmermann, H.
Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes
Eur. J. Biochem.
270
1802-1809
2003
Rattus norvegicus
Manually annotated by BRENDA team
Kukulski, F.; Komoszynski, M.
Purification and characterization of NTPDase1 (ecto-apyrase) and NTPDase2 (ecto-ATPase) from porcine brain cortex synaptosomes
Eur. J. Biochem.
270
3447-3454
2003
Sus scrofa
Manually annotated by BRENDA team
de Aguiar Matos, J.A.; Borges, F.P.; Tasca, T.; Bogo, M.R.; De Carli, G.A.; da Graca Fauth, M.; Dias, R.D.; Bonan, C.D.
Characterisation of an ATP diphosphohydrolase (Apyrase, EC 3.6.1.5) activity in Trichomonas vaginalis
Int. J. Parasitol.
31
770-775
2001
Trichomonas vaginalis
Manually annotated by BRENDA team
Shi, J.D.; Kukar, T.; Wang, C.Y.; Li, Q.Z.; Cruz, P.E.; Davoodi-Semiromi, A.; Yang, P.; Gu, Y.; Lian, W.; Wu, D.H.; She, J.X.
Molecular cloning and characterization of a novel mammalian endo-apyrase (LALP1)
J. Biol. Chem.
276
17474-17478
2001
Mus musculus (Q3TCT4), Mus musculus, Homo sapiens (Q9NQZ7), Homo sapiens
Manually annotated by BRENDA team
Murphy, D.M.; Ivanenkov, V.V.; Kirley, T.L.
Identification of cysteine residues responsible for oxidative cross-linking and chemical inhibition of human nucleoside-triphosphate diphosphohydrolase 3
J. Biol. Chem.
277
6162-6169
2002
Homo sapiens
Manually annotated by BRENDA team
Bruno, A.N.; Bonan, C.D.; Wofchuk, S.T.; Sarkis, J.J.; Battastini, A.M.
ATP diphosphohydrolase (NTPDase 1) in rat hippocampal slices and effect of glutamate on the enzyme activity in different phases of development
Life Sci.
71
215-225
2002
Rattus norvegicus
Manually annotated by BRENDA team
Pierre Oses, J.; Cardoso, C.M.; Albuquerque Germano, R.; Barreto Kirst, I.; Rucker, B.; Ribas Furstenau, C.; Wink, M.R.; Bonan, C.D.; Oliveira Battastini, A.M.; Freitas Sarkis, J.J.
Soluble NTPDase: An additional system of nucleotide hydrolysis in rat blood serum
Life Sci.
74
3275-3284
2004
Rattus norvegicus
Manually annotated by BRENDA team
Boeck, C.R.; Sarkis, J.J.; Vendite, D.
Kinetic characterization and immunodetection of ecto-ATP diphosphohydrolase (EC 3.6.1.5) in cultured hippocampal neurons
Neurochem. Int.
40
449-453
2002
Rattus norvegicus
Manually annotated by BRENDA team
Coimbra, E.S.; Goncalves-da-Costa, S.C.; Corte-Real, S.; De Freitas, F.G.; Durao, A.C.; Souza, C.S.; Silva-Santos, M.I.; Vasconcelos, E.G.
Characterization and cytochemical localization of an ATP diphosphohydrolase from Leishmania amazonensis promastigotes
Parasitology
124
137-143
2002
Leishmania amazonensis
Manually annotated by BRENDA team
Nedeljkovic, N.; Banjac, A.; Horvat, A.; Stojiljkovic, M.; Nikezic, G.
Ecto-ATPase and ecto-ATP-diphosphohydrolase are co-localized in rat hippocampal and caudate nucleus synaptic plasma membranes
Physiol. Res.
52
797-804
2003
Rattus norvegicus
Manually annotated by BRENDA team
Abe, S.; Moustafa, M.F.M.; Shibata, K.; Yoneda, M.; Davies, E.
Purification and characterization of the major isotypes of apyrase from the cytoskeleton fraction in Pisum sativum
Plant Physiol. Biochem.
40
1019-1023
2002
Pisum sativum
-
Manually annotated by BRENDA team
Nourizad, N.; Ehn, M.; Gharizadeh, B.; Hober, S.; Nyren, P.
Methylotrophic yeast Pichia pastoris as a host for production of ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum)
Protein Expr. Purif.
27
229-237
2003
Solanum tuberosum
Manually annotated by BRENDA team
Henz, S.L.; Ribeiro, C.G.; Rosa, A.; Chiarelli, R.A.; Casali, E.A.; Sarkis, J.J.
Kinetic characterization of ATP diphosphohydrolase and 5'-nucleotidase activities in cells cultured from submandibular salivary glands of rats
Cell Biol. Int.
30
214-220
2006
Rattus norvegicus
Manually annotated by BRENDA team
Devader, C.; Webb, R.J.; Thomas, G.M.; Dale, L.
Xenopus apyrase (xapy), a secreted nucleotidase that is expressed during early development
Gene
367
135-141
2006
Xenopus laevis
Manually annotated by BRENDA team
Faudry, E.; Santana, J.M.; Ebel, C.; Vernet, T.; Teixeira, A.R.
Salivary apyrases of Triatoma infestans are assembled into homo-oligomers
Biochem. J.
396
509-515
2006
Triatoma infestans
Manually annotated by BRENDA team
Leal, D.B.; Streher, C.A.; Neu, T.N.; Bittencourt, F.P.; Leal, C.A.; da Silva, J.E.; Morsch, V.M.; Schetinger, M.R.
Characterization of NTPDase (NTPDase1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6.1.5) activity in human lymphocytes
Biochim. Biophys. Acta
1721
9-15
2005
Homo sapiens
Manually annotated by BRENDA team
Vlajkovic, S.M.; Vinayagamoorthy, A.; Thorne, P.R.; Robson, S.C.; Wang, C.J.; Housley, G.D.
Noise-induced up-regulation of NTPDase3 expression in the rat cochlea: Implications for auditory transmission and cochlear protection
Brain Res.
1104
55-63
2006
Rattus norvegicus
Manually annotated by BRENDA team
Fonseca, F.V.; Fonseca de Souza, A.L.; Mariano, A.C.; Entringer, P.F.; Gondim, K.C.; Meyer-Fernandes, J.R.
Trypanosoma rangeli: characterization of a Mg-dependent ecto ATP-diphosphohydrolase activity
Exp. Parasitol.
112
76-84
2006
Trypanosoma rangeli
Manually annotated by BRENDA team
Pinheiro, C.M.; Martins-Duarte, E.S.; Ferraro, R.B.; Fonseca de Souza, A.L.; Gomes, M.T.; Lopes, A.H.; Vannier-Santos, M.A.; Santos, A.L.; Meyer-Fernandes, J.R.
Leishmania amazonensis: Biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities
Exp. Parasitol.
114
16-25
2006
Leishmania amazonensis
Manually annotated by BRENDA team
Faudry, E.; Rocha, P.S.; Vernet, T.; Lozzi, S.P.; Teixeira, A.R.
Kinetics of expression of the salivary apyrases in Triatoma infestans
Insect Biochem. Mol. Biol.
34
1051-1058
2004
Triatoma infestans (Q70GK8), Triatoma infestans
Manually annotated by BRENDA team
Nedeljkovic, N.; Banjac, A.; Horvat, A.; Stojiljkovic, M.; Nikezic, G.
Developmental profile of NTPDase activity in synaptic plasma membranes isolated from rat cerebral cortex
Int. J. Dev. Neurosci.
23
45-51
2005
Rattus norvegicus
Manually annotated by BRENDA team
Xu, W.; Jones, C.R.; Dunn, C.A.; Bessman, M.J.
Gene ytkD of Bacillus subtilis encodes an atypical nucleoside triphosphatase member of the Nudix hydrolase superfamily
J. Bacteriol.
186
8380-8384
2004
Bacillus subtilis
Manually annotated by BRENDA team
Faudry, E.; Lozzi, S.P.; Santana, J.M.; DSouza-Ault, M.; Kieffer, S.; Felix, C.R.; Ricart, C.A.; Sousa, M.V.; Vernet, T.; Teixeira, A.R.
Triatoma infestans apyrases belong to the 5-nucleotidase family
J. Biol. Chem.
279
19607-19613
2004
Triatoma infestans, Triatoma infestans (Q70GK8)
Manually annotated by BRENDA team
Haller, C.A.; Cui, W.; Wen, J.; Robson, S.C.; Chaikof, E.L.
Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties
J. Vasc. Surg.
43
816-823
2006
Homo sapiens
Manually annotated by BRENDA team
Barreto-Chaves, M.L.; Carneiro-Ramos, M.S.; Cotomacci, G.; Junior, M.B.; Sarkis, J.J.
E-NTPDase 3 (ATP diphosphohydrolase) from cardiomyocytes, activity and expression are modulated by thyroid hormone
Mol. Cell. Endocrinol.
251
49-55
2006
Rattus norvegicus
Manually annotated by BRENDA team
Belcher, S.M.; Zsarnovszky, A.; Crawford, P.A.; Hemani, H.; Spurling, L.; Kirley, T.L.
Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: Implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors
Neuroscience
137
1331-1346
2006
Rattus norvegicus
Manually annotated by BRENDA team
Faria-Pinto, P.; Meirelles, M.N.; Lenzi, H.L.; Mota, E.M.; Penido, M.L.; Coelho, P.M.; Vasconcelos, E.G.
ATP diphosphohydrolase from Schistosoma mansoni egg: characterization and immunocytochemical localization of a new antigen
Parasitology
129
51-57
2004
Schistosoma mansoni
Manually annotated by BRENDA team
Kettlun, A.M.; Espinosa, V.; Garcia, L.; Valenzuela, M.A.
Potato tuber isoapyrases: substrate specificity, affinity labeling, and proteolytic susceptibility
Phytochemistry
66
975-982
2005
Solanum tuberosum
Manually annotated by BRENDA team
McAlvin, C.B.; Stacey, G.
Transgenic expression of the soybean apyrase in Lotus japonicus enhances nodulation
Plant Physiol.
137
1456-1462
2005
Glycine max
Manually annotated by BRENDA team
Sun, D.; McNicol, A.; James, A.A.; Peng, Z.
Expression of functional recombinant mosquito salivary apyrase: a potential therapeutic platelet aggregation inhibitor
Platelets
17
178-184
2006
Aedes aegypti
Manually annotated by BRENDA team
Wakagi, T.; Oshima, T.
Membrane-bound ATPase of a thermoacidophilic archaebacterium, Sulfolobus acidocaldarius
Biochim. Biophys. Acta
817
33-41
1985
Sulfolobus acidocaldarius
Manually annotated by BRENDA team
Levano-Garcia, J.; Mortara, R.A.; Verjovski-Almeida, S.; DeMarco, R.
Characterization of Schistosoma mansoni ATPDase2 gene, a novel apyrase family member
Biochem. Biophys. Res. Commun.
352
384-389
2007
Schistosoma mansoni, Schistosoma mansoni (A1BXT9)
Manually annotated by BRENDA team
Leite, M.d.S.; Thomaz, R.; Fonseca, F.V.; Panizzutti, R.; Vercesi, A.E.; Meyer-Fernandes, J.R.
Trypanosoma brucei brucei: Biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities
Exp. Parasitol.
115
315-323
2007
Trypanosoma brucei brucei
Manually annotated by BRENDA team
Teixeira-Ferreira, A.; Alves, E.W.
Characterization of a novel ADPase in Bothrops jararaca snake venom involved in nucleotide hydrolysis
Protein Pept. Lett.
14
395-402
2007
Bothrops jararaca
Manually annotated by BRENDA team
Kozakiewicz, A.; Neumann, P.; Banach, M.; Komoszy?ski, M.; Wojtczak, A.
Modeling studies of potato nucleoside triphosphate diphosphohydrolase NTPDase1: an insight into the catalytic mechanism
Acta Biochim. Pol.
55
141-150
2008
Solanum tuberosum
Manually annotated by BRENDA team
Chiang, W.C.; Knowles, A.F.
Transmembrane domain interactions affect the stability of the extracellular domain of the human NTPDase 2
Arch. Biochem. Biophys.
472
89-99
2008
Gallus gallus (O93295), Gallus gallus, Homo sapiens (Q9Y5L3), Homo sapiens
Manually annotated by BRENDA team
Sivuk, V.F.; Rusina, I.M.; Makarchikov, A.F.
Purification and characteristics of functional properties of soluble nucleoside triphosphatase (apyrase) from bovine brain
Biochemistry (Moscow)
73
1047-1052
2008
Bos taurus
Manually annotated by BRENDA team
Lombardo, F.; Lycett, G.J.; Lanfrancotti, A.; Coluzzi, M.; Arca, B.
Analysis of apyrase 5 upstream region validates improved Anopheles gambiae transformation technique
BMC Res. Notes
2
24
2009
Anopheles gambiae
Manually annotated by BRENDA team
Stutzer, C.; Mans, B.J.; Gaspar, A.R.; Neitz, A.W.; Maritz-Olivier, C.
Ornithodoros savignyi: Soft tick apyrase belongs to the 5'-nucleotidase family
Exp. Parasitol.
122
318-327
2009
Ornithodoros savignyi (A7LH73), Ornithodoros savignyi (A7LH74), Ornithodoros savignyi
Manually annotated by BRENDA team
Sansom, F.M.; Riedmaier, P.; Newton, H.J.; Dunstone, M.A.; Mueller, C.E.; Stephan, H.; Byres, E.; Beddoe, T.; Rossjohn, J.; Cowan, P.J.; dApice, A.J.; Robson, S.C.; Hartland, E.L.
Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence
J. Biol. Chem.
283
12909-12918
2008
Legionella pneumophila
Manually annotated by BRENDA team
Hyman, M.C.; Petrovic-Djergovic, D.; Visovatti, S.H.; Liao, H.; Yanamadala, S.; Bouis, D.; Su, E.J.; Lawrence, D.A.; Broekman, M.J.; Marcus, A.J.; Pinsky, D.J.
Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39
J. Clin. Invest.
119
1136-1149
2009
Mus musculus
Manually annotated by BRENDA team
Guevara-Flores, A.; Olvera-Sanchez, S.; Gomez-Concha, C.; Juarez, O.; Esparza-Perusquia, M.; Pardo, J.P.; Mendoza-Hernandez, G.; Martinez, F.; Flores-Herrera, O.
5-p-Fluorosulfonyl benzoyl adenosine inhibits an ecto-ATP-diphosphohydrolase in the tegument surface of Taenia crassiceps cysticerci
Mol. Biochem. Parasitol.
162
123-133
2008
Taenia crassiceps
Manually annotated by BRENDA team
Uccelletti, D.; Pascoli, A.; Farina, F.; Alberti, A.; Mancini, P.; Hirschberg, C.B.; Palleschi, A.C.
APY-1, a novel Caenorhabditis elegans apyrase involved in unfolded protein response signalling and stress responses
Mol. Biol. Cell
19
1337-1345
2008
Homo sapiens
Manually annotated by BRENDA team
Faria-Pinto, P.; Rezende-Soares, F.A.; Molica, A.M.; Montesano, M.A.; Marques, M.J.; Rocha, M.O.; Gomes, J.A.; Enk, M.J.; Correa-Oliveira, R.; Coelho, P.M.; Neto, S.M.; Franco, O.L.; Vasconcelos, E.G.
Mapping of the conserved antigenic domains shared between potato apyrase and parasite ATP diphosphohydrolases: potential application in human parasitic diseases
Parasitology
135
943-953
2008
Schistosoma mansoni (A1BXT9), Schistosoma mansoni, Solanum tuberosum (P80595), Solanum tuberosum
Manually annotated by BRENDA team
Riewe, D.; Grosman, L.; Fernie, A.R.; Wucke, C.; Geigenberger, P.
The potato-specific apyrase is apoplastically localized and has influence on gene expression, growth, and development
Plant Physiol.
147
1092-1109
2008
Solanum tuberosum
Manually annotated by BRENDA team
Govindarajulu, M.; Kim, S.Y.; Libault, M.; Berg, R.H.; Tanaka, K.; Stacey, G.; Taylor, C.G.
GS52 ecto-apyrase plays a critical role during soybean nodulation
Plant Physiol.
149
994-1004
2009
Glycine soja
Manually annotated by BRENDA team
Santos, R.F.; Possa, M.A.; Bastos, M.S.; Guedes, P.M.; Almeida, M.R.; Demarco, R.; Verjovski-Almeida, S.; Bahia, M.T.; Fietto, J.L.
Influence of Ecto-nucleoside triphosphate diphosphohydrolase activity on Trypanosoma cruzi infectivity and virulence
PLoS Negl. Trop. Dis.
3
e387
2009
Trypanosoma cruzi (Q6QHT8), Trypanosoma cruzi
Manually annotated by BRENDA team
Ricatti, M.J.; Alfie, L.D.; Lavoie, E.G.; Sevigny, J.; Schwarzbaum, P.J.; Faillace, M.P.
Immunocytochemical localization of NTPDases1 and 2 in the neural retina of mouse and zebrafish
Synapse
63
291-307
2009
Danio rerio, Mus musculus (P55772), Mus musculus
Manually annotated by BRENDA team
Kiffer-Moreira, T.; Fernandes Sampaio, M.E.; Alviano, D.S.; Axelband, F.; Cesar, G.V.; Cosentino-Gomes, D.; Rodrigues, M.L.; Nimrichter, L.; Vieyra, A.; Alviano, C.S.; Meyer-Fernandes, J.R.
Biochemical characterization of an ecto-ATP diphosphohydrolase activity in Candida parapsilosis and its possible role in adenosine acquisition and pathogenesis
FEMS Yeast Res.
10
735-746
2010
Candida parapsilosis, Candida parapsilosis CCT3834
Manually annotated by BRENDA team
Hamasaki, R.; Kato, H.; Terayama, Y.; Iwata, H.; Valenzuela, J.G.
Functional characterization of a salivary apyrase from the sand fly, Phlebotomus duboscqi, a vector of Leishmania major
J. Insect Physiol.
55
1044-1049
2009
Phlebotomus duboscqi (Q06K73), Phlebotomus duboscqi (Q06K77), Phlebotomus duboscqi
Manually annotated by BRENDA team
Rezende-Soares, F.A.; Carvalho-Campos, C.; Marques, M.J.; Porcino, G.N.; Giarola, N.L.; Costa, B.L.; Taunay-Rodrigues, A.; Faria-Pinto, P.; Souza, M.A.; Diniz, V.A.; Corte-Real, S.; Juliano, M.A.; Juliano, L.; Vasconcelos, E.G.
Cytochemical localization of ATP diphosphohydrolase from Leishmania (Viannia) braziliensis promastigotes and identification of an antigenic and catalytically active isoform
Parasitology
137
773-783
2010
Leishmania braziliensis
Manually annotated by BRENDA team
Clark, G.; Torres, J.; Finlayson, S.; Guan, X.; Handley, C.; Lee, J.; Kays, J.E.; Chen, Z.J.; Roux, S.J.
Apyrase (nucleoside triphosphate-diphosphohydrolase) and extracellular nucleotides regulate cotton fiber elongation in cultured ovules
Plant Physiol.
152
1073-1083
2010
Gossypium hirsutum
Manually annotated by BRENDA team
Yoneda, M.; Davies, E.; Morita, E.H.; Abe, S.
Immunohistochemical localization of apyrase during initial differentiation and germination of pea seeds
Planta
231
47-56
2009
Pisum sativum (Q9FEA6), Pisum sativum
Manually annotated by BRENDA team
Fausther, M.; Lecka, J.; Soliman, E.; Kauffenstein, G.; Pelletier, J.; Sheung, N.; Dranoff, J.; Sevigny, J.
Coexpression of ecto-5'-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver
Am. J. Physiol. Gastrointest. Liver Physiol.
302
447-459
2012
Rattus norvegicus (O35795), Rattus norvegicus (P97687), Rattus norvegicus (Q5DRK1), Rattus norvegicus Sprague-Dawley (O35795), Rattus norvegicus Sprague-Dawley (P97687), Rattus norvegicus Sprague-Dawley (Q5DRK1)
Manually annotated by BRENDA team
Li, C.; Lee, Y.; Knowles, A.
The stability of chicken nucleoside triphosphate diphosphohydrolase 8 requires both of its transmembrane domains
Biochemistry
49
134-146
2010
Gallus gallus (O93295), Gallus gallus
Manually annotated by BRENDA team
Fenckova, M.; Hobizalova, R.; Fric, Z.F.; Dolezal, T.
Functional characterization of ecto-5-nucleotidases and apyrases in Drosophila melanogaster
Insect Biochem. Mol. Biol.
41
956-967
2011
Drosophila melanogaster
Manually annotated by BRENDA team
Zebisch, M.; Krauss, M.; Schaefer, P.; Straeter, N.
Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1
J. Mol. Biol.
415
288-306
2012
Rattus norvegicus (P97687)
Manually annotated by BRENDA team
Andrade, C.; Wink, M.; Margis, R.; Borojevic, R.; Battastini, A.; Guma, F.
Changes in E-NTPDase 3 expression and extracellular nucleotide hydrolysis during the myofibroblast/lipocyte differentiation
Mol. Cell. Biochem.
339
79-87
2010
Mus musculus
Manually annotated by BRENDA team
Dong, F.; Fu, Y.; Li, X.; Jiang, J.; Sun, J.; Cheng, X.
Cloning, expression, and characterization of salivary apyrase from Aedes albopictus
Parasitol. Res.
110
931-937
2012
Aedes albopictus (E0D877), Aedes albopictus
Manually annotated by BRENDA team
Tanaka, K.; Nguyen, C.T.; Libault, M.; Cheng, J.; Stacey, G.
Enzymatic activity of the soybean ecto-apyrase GS52 is essential for stimulation of nodulation
Plant Physiol.
155
1988-1998
2011
Glycine max
Manually annotated by BRENDA team
Clark, G.; Fraley, D.; Steinebrunner, I.; Cervantes, A.; Onyirimba, J.; Liu, A.; Torres, J.; Tang, W.; Kim, J.; Roux, S.J.
Extracellular nucleotides and apyrases regulate stomatal aperture in Arabidopsis
Plant Physiol.
156
1740-1753
2011
Arabidopsis thaliana
Manually annotated by BRENDA team
Okuhata, R.; Takishima, T.; Nishimura, N.; Ueda, S.; Tsuchiya, T.; Kanzawa, N.
Purification and biochemical characterization of a novel ecto-apyrase, MP67, from Mimosa pudica
Plant Physiol.
157
464-475
2011
Mimosa pudica, Mimosa pudica (G1UFQ9)
Manually annotated by BRENDA team
Tanaka, K.; Nguyen, T.H.; Stacey, G.
Enzymatic role for soybean ecto-apyrase in nodulation
Plant Signal. Behav.
6
1034-1036
2011
Glycine soja (Q9FVC2)
Manually annotated by BRENDA team
Manque, P.A.; Woehlbier, U.; Lara, A.M.; Tenjo, F.; Alves, J.M.; Buck, G.A.
Identification and characterization of a novel calcium-activated apyrase from Cryptosporidium parasites and its potential role in pathogenesis
PLoS ONE
7
e31030
2012
Cryptosporidium parvum (Q5CXD0), Cryptosporidium parvum
Manually annotated by BRENDA team
Zebisch, M.; Schaefer, P.; Lauble, P.; Straeter, N.
New crystal forms of NTPDase1 from the bacterium Legionella pneumophila
Acta Crystallogr. Sect. F
69
257-262
2013
Legionella pneumophila
Manually annotated by BRENDA team
Syed, S.K.; Kauffman, A.L.; Beavers, L.S.; Alston, J.T.; Farb, T.B.; Ficorilli, J.; Marcelo, M.C.; Brenner, M.B.; Bokvist, K.; Barrett, D.G.; Efanov, A.M.
Ectonucleotidase NTPDase3 is abundant in pancreatic beta-cells and regulates glucose-induced insulin secretion
Am. J. Physiol. Endocrinol. Metab.
305
E1319-E1326
2013
Homo sapiens (O75355), Homo sapiens, Mus musculus (Q8BFW6), Mus musculus
Manually annotated by BRENDA team
De Lima Detoni, M.; Faria-Pinto, P.; Quellis, L.; Rust, N.; Tavares, L.; De Oliveira Santos, M.; Isaias, R.; Santos, J.; Fernandes, G.; Soares, G.; Vasconcelos, E.
Galls from Calliandra brevipes BENTH (Fabaceae: Mimosoidae): Evidence of apyrase activity contribution in a plant-insect interaction
Aust. J. Bot.
60
559-567
2012
Calliandra brevipes
-
Manually annotated by BRENDA team
Schiller, M.; Massalski, C.; Kurth, T.; Steinebrunner, I.
The Arabidopsis apyrase AtAPY1 is localized in the Golgi instead of the extracellular space
BMC Plant Biol.
12
123
2012
Arabidopsis thaliana (Q9SQG2)
Manually annotated by BRENDA team
Krug, U.; Totzauer, R.; Zebisch, M.; Straeter, N.
The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base
ChemBioChem
14
2292-2300
2013
Toxoplasma gondii (Q27895), Toxoplasma gondii
Manually annotated by BRENDA team
Porcino, G.N.; Carvalho-Campos, C.; Maia, A.C.; Detoni, M.L.; Faria-Pinto, P.; Coimbra, E.S.; Marques, M.J.; Juliano, M.A.; Juliano, L.; Diniz, V.A.; Corte-Real, S.; Vasconcelos, E.G.
Leishmania (Viannia) braziliensis nucleoside triphosphate diphosphohydrolase (NTPDase 1): localization and in vitro inhibition of promastigotes growth by polyclonal antibodies
Exp. Parasitol.
132
293-299
2012
Leishmania braziliensis, Leishmania braziliensis MHOM/BR/1975/M2903
Manually annotated by BRENDA team
Rooklin, D.W.; Lu, M.; Zhang, Y.
Revelation of a catalytic calcium-binding site elucidates unusual metal dependence of a human apyrase
J. Am. Chem. Soc.
134
15595-15603
2012
Homo sapiens (Q8WVQ1), Homo sapiens
Manually annotated by BRENDA team
Zebisch, M.; Baqi, Y.; Schaefer, P.; Mueller, C.E.; Straeter, N.
Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071
J. Struct. Biol.
185
336-341
2014
Rattus norvegicus (O35795)
Manually annotated by BRENDA team
Maia, A.C.; Porcino, G.N.; Detoni, M.d.e..L.; Emidio, N.B.; Marconato, D.G.; Faria-Pinto, P.; Fessel, M.R.; Reis, A.B.; Juliano, L.; Juliano, M.A.; Marques, M.J.; Vasconcelos, E.G.
An antigenic domain within a catalytically active Leishmania infantum nucleoside triphosphate diphosphohydrolase (NTPDase 1) is a target of inhibitory antibodies
Parasitol. Int.
62
44-52
2013
Leishmania infantum
Manually annotated by BRENDA team
Wujak, M.; Banach, M.; Porowinska, D.; Piskulak, K.; Komoszynski, M.
Isolation and bioinformatic analysis of seven genes encoding potato apyrase. Bacterial overexpresssion, refolding and initial kinetic studies on some recombinant potato apyrases
Phytochemistry
93
8-17
2013
Solanum tuberosum
Manually annotated by BRENDA team
Yang, J.; Wu, J.; Romanovicz, D.; Clark, G.; Roux, S.J.
Co-regulation of exine wall patterning, pollen fertility and anther dehiscence by Arabidopsis apyrases 6 and 7
Plant Physiol. Biochem.
69
62-73
2013
Arabidopsis thaliana
Manually annotated by BRENDA team
Liu, X.; Wu, J.; Clark, G.; Lundy, S.; Lim, M.; Arnold, D.; Chan, J.; Tang, W.; Muday, G.K.; Gardner, G.; Roux, S.J.
Role for apyrases in polar auxin transport in Arabidopsis
Plant Physiol.
160
1985-1995
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Okuhata, R.; Otsuka, Y.; Tsuchiya, T.; Kanzawa, N.
Mutagenesis of apyrase conserved region 1 alters the nucleotide substrate specificity
Plant Signal. Behav.
8
e24131
2013
Mimosa pudica (G1UFQ9), Mimosa pudica (G1UFR4), Mimosa pudica
Manually annotated by BRENDA team
Clark, G.; Darwin, C.; Mehta, V.; Jackobs, F.; Perry, T.; Hougaard, K.; Roux, S.
Effects of chemical inhibitors and apyrase enzyme further document a role for apyrases and extracellular ATP in the opening and closing of stomates in Arabidopsis
Plant Signal. Behav.
8
e26093
2013
Arabidopsis thaliana
Manually annotated by BRENDA team
Massalski, C.; Bloch, J.; Zebisch, M.; Steinebrunner, I.
The biochemical properties of the Arabidopsis ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 contradict a direct role in purinergic signaling
PLoS ONE
10
e0115832
2015
Arabidopsis thaliana (Q9SQG2)
Manually annotated by BRENDA team
Ho, C.L.; Yang, C.Y.; Lin, W.J.; Lin, C.H.
Ecto-nucleoside triphosphate diphosphohydrolase 2 modulates local ATP-induced calcium signaling in human HaCaT keratinocytes
PLoS ONE
8
e57666
2013
Homo sapiens (Q9Y5L3), Homo sapiens
Manually annotated by BRENDA team
Vandenbeuch, A.; Anderson, C.B.; Parnes, J.; Enjyoji, K.; Robson, S.C.; Finger, T.E.; Kinnamon, S.C.
Role of the ectonucleotidase NTPDase2 in taste bud function
Proc. Natl. Acad. Sci. USA
110
14789-14794
2013
Mus musculus (O55026)
Manually annotated by BRENDA team
Krug, U.; Totzauer, R.; Straeter, N.
The crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 represents a conformational intermediate in the reductive activation mechanism of the tetrameric enzyme
Proteins
81
1271-1276
2013
Toxoplasma gondii (Q27895), Toxoplasma gondii
Manually annotated by BRENDA team
Moustafa, M.
Apyrase, streptavidin-binding proteins, and antimicrobial activity in Pisum sativum
Russ. J. Plant Physiol.
61
496-502
2014
Pisum sativum (Q9FEA6)
-
Manually annotated by BRENDA team
Pelletier, J.; Salem, M.; Lecka, J.; Fausther, M.; Bigonnesse, F.; Sevigny, J.
Generation and characterization of specific antibodies to the murine and human ectonucleotidase NTPDase8
Front. Pharmacol.
8
115
2017
Homo sapiens (Q5MY95), Homo sapiens, Mus musculus (Q8K0L2), Mus musculus
Manually annotated by BRENDA team
Fiene, A.; Baqi, Y.; Lecka, J.; Sevigny, J.; Mueller, C.
Fluorescence polarization immunoassays for monitoring nucleoside triphosphate diphosphohydrolase (NTPDase) activity
Analyst
140
140-148
2015
Homo sapiens (O75355), Homo sapiens (P49961), Homo sapiens (Q5MY95), Homo sapiens (Q9Y5L3)
Manually annotated by BRENDA team
Lee, S.Y.; Luo, X.; Namasivayam, V.; Geiss, J.; Mirza, S.; Pelletier, J.; Stephan, H.; Sevigny, J.; Mueller, C.E.
Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39)
Analyst
143
5417-5430
2018
Homo sapiens (O75355), Homo sapiens (P49961), Homo sapiens (Q5MY95), Homo sapiens (Q9Y5L3), Homo sapiens
Manually annotated by BRENDA team
Chiu, T.Y.; Lao, J.; Manalansan, B.; Loque, D.; Roux, S.J.; Heazlewood, J.L.
Biochemical characterization of Arabidopsis APYRASE family reveals their roles in regulating endomembrane NDP/NMP homoeostasis
Biochem. J.
472
43-54
2015
no activity by Arabidopsis thaliana isozyme AtAPY7, Arabidopsis thaliana (O80612), Arabidopsis thaliana (Q6NQA8), Arabidopsis thaliana (Q8H1D8), Arabidopsis thaliana (Q9SPM5), Arabidopsis thaliana (Q9SQG2), Arabidopsis thaliana (Q9XI62)
Manually annotated by BRENDA team
Beckenkamp, L.R.; Iser, I.C.; Onzi, G.R.; Fontoura, D.M.S.D.; Bertoni, A.P.S.; Sevigny, J.; Lenz, G.; Wink, M.R.
Characterization of soluble CD39 (SolCD39/NTPDase1) from PiggyBac nonviral system as a tool to control the nucleotides level
Biochem. J.
476
1637-1651
2019
Rattus norvegicus (P97687)
Manually annotated by BRENDA team
Endo, S.; Kato, R.; Sawada, K.; Hattori, T.
Two-dimensional array ATP/ADP sensitive image sensor with a uniform distribution of chemically immobilized apyrase
Bull. Chem. Soc. JPN
91
304-310
2018
Solanum tuberosum (P80595)
-
Manually annotated by BRENDA team
Dias, D.A.; de Barros Penteado, B.; Dos Santos, L.D.; Dos Santos, P.M.; Arruda, C.C.P.; Schetinger, M.R.C.; Leal, D.B.R.; Dos Santos Jaques, J.A.
Characterization of ectonucleoside triphosphate diphosphohydrolase (E-NTPDase; EC 3.6.1.5) activity in mouse peritoneal cavity cells
Cell Biochem. Funct.
35
358-363
2017
Mus musculus (P55772), Mus musculus, Mus musculus BALB/c (P55772)
Manually annotated by BRENDA team
Paes-Vieira, L.; Gomes-Vieira, A.L.; Meyer-Fernandes, J.R.
NTPDase activities possible roles on Leishmania spp. infectivity and virulence
Cell Biol. Int.
42
670-682
2018
Leishmania major (Q4QFI1)
Manually annotated by BRENDA team
Tonin, A.; Da Silva, A.; Zanini, D.; Pelinson, L.; Schetinger, M.; Camillo, G.; Vogel, F.; de La Rue, M.; Jaques, J.; Lopes, S.
Biochemical detection of enzymes NTPDase in tachyzoites of Toxoplasma gondii and possible functional correlations
Comp. Clin. Pathol.
24
393-397
2015
Toxoplasma gondii, Toxoplasma gondii RH
-
Manually annotated by BRENDA team
Channar, P.A.; Afzal, S.; Ejaz, S.A.; Saeed, A.; Larik, F.A.; Mahesar, P.A.; Lecka, J.; Sevigny, J.; Erben, M.F.; Iqbal, J.
Exploration of carboxy pyrazole derivatives synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile
Eur. J. Med. Chem.
156
461-478
2018
Rattus norvegicus (O35795), Rattus norvegicus (P97687), Rattus norvegicus (Q5DRK1), Rattus norvegicus (Q80Z26)
Manually annotated by BRENDA team
Maia, A.C.R.G.; Porcino, G.N.; Detoni, M.L.; Quellis, L.R.; Emidio, N.B.; Marconato, D.G.; Messias, W.F.; Soldati, L.L.; Faria-Pinto, P.; Capriles, P.V.; Coimbra, E.S.; Marques, M.J.; Vasconcelos, E.G.
Leishmania infantum amastigote nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) Its inhibition as a new insight into mode of action of pentamidine
Exp. Parasitol.
200
1-6
2019
Leishmania infantum, Leishmania infantum MHOM/BR/1972/BH46
Manually annotated by BRENDA team
Cao, L.; Liu, B.; Li, J.; Yu, N.; Zou, X.; Chen, L.
Light- and temperature-regulated BjAPY2 may have a role in stem expansion of Brassica juncea
Funct. Integr. Genomics
15
753-762
2015
Brassica juncea
Manually annotated by BRENDA team
Kalita, B.; Patra, A.; Jahan, S.; Mukherjee, A.K.
First report of the characterization of a snake venom apyrase (Ruviapyrase) from Indian Russells viper (Daboia russelii) venom
Int. J. Biol. Macromol.
111
639-648
2018
Daboia russelii
Manually annotated by BRENDA team
Ramachandran, B.; Muthuvijayan, V.
Kinetic study of NTPDase immobilization and its effect of haemocompatibility on polyethylene terephthalate
J. Biomat. Sci.
30
437-449
2019
Solanum tuberosum
Manually annotated by BRENDA team
Magalhaes, L.; de Oliveira, A.H.C.; de Souza Vasconcellos, R.; Mariotini-Moura, C.; de Cassia Firmino, R.; Fietto, J.L.R.; Cardoso, C.L.
Label-free assay based on immobilized capillary enzyme reactor of Leishmania infantum nucleoside triphosphate diphosphohydrolase (LicNTPDase-2-ICER-LC/UV)
J. Chromatogr. B
1008
98-107
2016
Leishmania infantum (K7ZBX8), Leishmania infantum
Manually annotated by BRENDA team
Thievent, K.; Zilio, G.; Hauser, G.; Koella, J.C.
Malaria load affects the activity of mosquito salivary apyrase
J. Insect Physiol.
116
10-16
2019
Anopheles gambiae (Q9TW03), Anopheles gambiae
Manually annotated by BRENDA team
da Silva, C.; Paim, F.; Wolkmer, P.; Abdalla, F.; Carvalho, F.; Palma, H.; Mello, C.; Flores, E.; Andrade, C.; Lopes, S.
NTPDase and 5'-nucleotidase activities in synaptosomes of rabbits experimentally infected with BoHV-5
J. Neurovirol.
21
518-524
2015
Oryctolagus cuniculus
Manually annotated by BRENDA team
Ji, Y.; Adeola, O.; Strawn, T.L.; Jeong, S.S.; Chen, R.; Fay, W.P.
Recombinant soluble apyrase APT102 inhibits thrombosis and intimal hyperplasia in vein grafts without adversely affecting hemostasis or re-endothelialization
J. Thromb. Haemost.
15
814-825
2017
Homo sapiens
Manually annotated by BRENDA team
Liu, W.; Ni, J.; Shah, F.A.; Ye, K.; Hu, H.; Wang, Q.; Wang, D.; Yao, Y.; Huang, S.; Hou, J.; Liu, C.; Wu, L.
Genome-wide identification, characterization and expression pattern analysis of APYRASE family members in response to abiotic and biotic stresses in wheat
PeerJ
7
e7622
2019
Triticum aestivum
Manually annotated by BRENDA team
Veerappa, R.; Slocum, R.D.; Siegenthaler, A.; Wang, J.; Clark, G.; Roux, S.J.
Ectopic expression of a pea apyrase enhances root system architecture and drought survival in Arabidopsis and soybean
Plant Cell Environ.
42
337-353
2019
Pisum sativum (Q9FEA6), Pisum sativum, Arabidopsis thaliana (Q9SPM5), Arabidopsis thaliana (Q9SQG2), Arabidopsis thaliana ecotype Columbia, CS907 (Q9SPM5), Arabidopsis thaliana ecotype Columbia, CS907 (Q9SQG2)
Manually annotated by BRENDA team
Yang, X.; Wang, B.; Farris, B.; Clark, G.; Roux, S.J.
Modulation of root skewing in Arabidopsis by apyrases and extracellular ATP
Plant Cell Physiol.
56
2197-2206
2015
Arabidopsis thaliana (Q9SPM5), Arabidopsis thaliana (Q9SQG2)
Manually annotated by BRENDA team
Deng, S.; Sun, J.; Zhao, R.; Ding, M.; Zhang, Y.; Sun, Y.; Wang, W.; Tan, Y.; Liu, D.; Ma, X.; Hou, P.; Wang, M.; Lu, C.; Shen, X.; Chen, S.
Populus euphratica APYRASE2 enhances cold tolerance by modulating vesicular trafficking and extracellular ATP in Arabidopsis plants
Plant Physiol.
169
530-548
2015
Populus euphratica
Manually annotated by BRENDA team
Madry, C.; Arancibia-Carcamo, I.L.; Kyrargyri, V.; Chan, V.T.T.; Hamilton, N.B.; Attwell, D.
Effects of the ecto-ATPase apyrase on microglial ramification and surveillance reflect cell depolarization, not ATP depletion
Proc. Natl. Acad. Sci. USA
115
E1608-E1617
2018
Solanum tuberosum
Manually annotated by BRENDA team
Veloria, J.R.; Devkota, A.K.; Cho, E.J.; Dalby, K.N.
Optimization of a luminescence-based high-throughput screening assay for detecting apyrase activity
SLAS Discov.
22
94-101
2017
Solanum tuberosum
Manually annotated by BRENDA team
Roberts, V.; Campbell, D.J.; Lu, B.; Chia, J.; Cowan, P.J.; Dwyer, K.M.
The differential effect of apyrase treatment and hCD39 overexpression on chronic renal fibrosis after ischemia-reperfusion injury
Transplantation
101
e194-e204
2017
Homo sapiens (P49961), Homo sapiens
Manually annotated by BRENDA team
Maia, A.C.R.G.; Porcino, G.N.; Faria-Pinto, P.; Mendes, T.V.; Antinarelli, L.M.R.; Coimbra, E.S.; Reis, A.B.; Juliano, L.; Juliano, M.A.; Marques, M.J.; Vasconcelos, E.G.
Leishmania infantum nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) B-domain Antibody antiproliferative effect on the promastigotes and IgG subclass responses in canine visceral leishmaniasis
Vet. Parasitol.
271
38-44
2019
Leishmania braziliensis (A4H7X3), Leishmania infantum (A4HWA0), Leishmania infantum MHOM/BR/1972/BH46 (A4HWA0)
Manually annotated by BRENDA team