Information on EC 3.6.1.26 - CDP-diacylglycerol diphosphatase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY hide
3.6.1.26
-
RECOMMENDED NAME
GeneOntology No.
CDP-diacylglycerol diphosphatase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CDP-diacylglycerol + H2O = CMP + phosphatidate
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphorous acid anhydride hydrolysis
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-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Biosynthesis of secondary metabolites
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Glycerophospholipid metabolism
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-
SYSTEMATIC NAME
IUBMB Comments
CDP-diacylglycerol phosphatidylhydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
62213-20-1
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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-
-
Manually annotated by BRENDA team
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-
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CDP-1-stearoyl-2-oleoylglycerol + H2O
CMP + 1-stearoyl-2-oleoyl-sn-glycerol-3-phosphate
show the reaction diagram
-
-
-
?
CDP-1-stearoyl-2-stearoylglycerol + H2O
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
show the reaction diagram
-
-
-
?
CDPdiacylglycerol + H2O
CMP + phosphatidate
show the reaction diagram
CDPdipalmitoylglycerol + H2O
CMP + 1,2-dipalmitoyl-sn-glycerol-3-phosphate
show the reaction diagram
-
-
-
?
CDPdistearoylglycerol + H2O
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
CDPdiacylglycerol + H2O
CMP + phosphatidate
show the reaction diagram
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
no requirement for added metal ions
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
CMP
-
no inhibition
UMP
-
slight inhibition
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Triton X-100
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.04
CDP-1-stearoyl-2-oleoylglycerol
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-
0.047
CDP-1-stearoyl-2-stearoylglycerol
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-
0.063
CDPdipalmitoylglycerol
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-
0.14
CDPdistearoylglycerol
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-
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Show AA Sequence (1131 entries)
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