Information on EC 3.6.1.2 - trimetaphosphatase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.6.1.2
-
RECOMMENDED NAME
GeneOntology No.
trimetaphosphatase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
trimetaphosphate + H2O = triphosphate
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphorous acid anhydride hydrolysis
SYSTEMATIC NAME
IUBMB Comments
trimetaphosphate hydrolase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9024-84-4
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Pekin duck
-
-
Manually annotated by BRENDA team
fowl
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
beta-glycerophosphate + H2O
?
show the reaction diagram
-
-
-
-
?
cytidine-5'-monophosphate + H2O
?
show the reaction diagram
-
-
-
-
?
trimetaphosphate
tripolyphosphate
show the reaction diagram
trimetaphosphate + H2O
triphosphate
show the reaction diagram
trimetaphosphate + H2O
triphosphate + diphosphate + phosphate
show the reaction diagram
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
trimetaphosphate
tripolyphosphate
show the reaction diagram
trimetaphosphate + H2O
triphosphate
show the reaction diagram
additional information
?
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Cu2+
-
inhibitory
Fe2+
-
inhibitory
Mg2+
-
very strong activation of enzyme
Ni2+
-
very weak activation
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
arsenate
-
slight inhibition
azide
-
slight inhibition
glutathione
-
slight inhibition
KCN
-
strong inhibitor
NaF
-
strong inhibitor
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37
-
assay at
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
in round or elongated vesicles in intestinal extrahepatic stellate cells
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
130000
-
gel filtration
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
33
-
40% loss of activity within 3 h
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partial purification
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
-
histochemical marker for lysosomes in light and electron microscopy
diagnostics
-
the enzyme is a cytochemical marker for lysosomes