Information on EC 3.5.5.2 - ricinine nitrilase

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The expected taxonomic range for this enzyme is: Pseudomonas sp.

EC NUMBER
COMMENTARY hide
3.5.5.2
-
RECOMMENDED NAME
GeneOntology No.
ricinine nitrilase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ricinine + 2 H2O = 3-carboxy-4-methoxy-N-methyl-2-pyridone + NH3
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of amide bond
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
ricinine degradation
-
-
SYSTEMATIC NAME
IUBMB Comments
ricinine aminohydrolase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9075-40-5
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-cyano-2-pyridone + H2O
3-carboxy-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
3-cyano-4-methoxy-2-pyridone + H2O
3-carboxy-4-methoxy-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
N-ethyl-3-cyano-4-ethoxy-2-pyridone + H2O
N-ethyl-3-carboxy-4-ethoxy-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
N-ethyl-3-cyano-4-methoxy-2-pyridone + H2O
N-ethyl-3-carboxy-4-methoxy-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
N-methyl-3-cyano-2-pyridone + H2O
N-methyl-3-carboxy-2-pyridone
show the reaction diagram
-
-
-
-
?
N-methyl-3-cyano-4-ethoxy-2-pyridone + H2O
N-methyl-3-carboxy-4-ethoxy-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
N-methyl-3-cyano-4-methoxy-2-pyridone + H2O
N-methyl-3-carboxy-4-methoxy-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
ricinine + H2O
3-carboxy-4-methoxy-N-methyl-2-pyridone + NH3
show the reaction diagram
-
-
-
-
?
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
diisopropyl fluorophosphate
-
0.3 mM
p-hydroxymercuribenzoate
Sodium cyanide
-
29 mM
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.05
N-ethyl-3-cyano-4-methoxy-2-pyridone
-
-
0.019
ricinine
-
-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6 - 11
-
-
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE