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Information on EC 3.5.2.3 - dihydroorotase and Organism(s) Saccharomyces cerevisiae and UniProt Accession P20051

for references in articles please use BRENDA:EC3.5.2.3
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EC Tree
     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.3 dihydroorotase
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Saccharomyces cerevisiae
UNIPROT: P20051 not found.
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The taxonomic range for the selected organisms is: Saccharomyces cerevisiae
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
dihydroorotase, dho, dhoase, dihydroorotase domain, hudhoase, type i dhoase, human dhoase domain, type ii dho, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
carbamoylaspartic dehydrase
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-
-
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DHOase
dihydroorotate dehydrolase
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of cyclic amides
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-
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formation of cyclic amides
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PATHWAY SOURCE
PATHWAYS
-
-, -, -
SYSTEMATIC NAME
IUBMB Comments
(S)-dihydroorotate amidohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
9024-93-5
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression of yeast-hamster chimeric proteins in Escherichia coli
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
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growth conditions which maintain DHOase overproduction require supplementation of Yeast Carbon Base with asparagines 5 g/l, glucose 20 g/l at pH 5.5. In this medium DHOase activity decreases with time, thus in terms of DHOase yield, the best time for harvesting cells is reached after 30 to 38 h of growth
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Serre, V.; Guy, H.; Liu, X.; Penverne, B.; Herve, G.; Evans, D.
Allosteric regulation and substrate channeling in multifunctional pyrimidine biosynthetic complexes: analysis of isolated domains and yeast-mammalian chimeric proteins
J. Mol. Biol.
281
363-377
1998
Saccharomyces cerevisiae, Cricetinae
Manually annotated by BRENDA team
Lee, M.; Chan, C.W.; Mitchell Guss, J.; Christopherson, R.I.; Maher, M.J.
Dihydroorotase from Escherichia coli: loop movement and cooperativity between subunits
J. Mol. Biol.
348
523-533
2005
Arabidopsis thaliana (O04904), Escherichia coli (P05020), Escherichia coli, Mesocricetus auratus (P08955), Saccharomyces cerevisiae (P20051), Homo sapiens (P27708), Helicobacter pylori (P56465), Plasmodium falciparum (Q8IKA9)
Manually annotated by BRENDA team
Robles Lopez, S.M.; Hortua Triana, M.A.; Zimmermann, B.H.
Cloning and preliminary characterization of the dihydroorotase from Toxoplasma gondii
Mol. Biochem. Parasitol.
148
93-98
2006
Saccharomyces cerevisiae, Mycobacterium leprae, Plasmodium berghei (A0A509AX79), Arabidopsis thaliana (O04904), Trypanosoma cruzi (O76138), Escherichia coli (P05020), Mesocricetus auratus (P08955), Homo sapiens (P27708), Ustilago maydis (P31301), Toxoplasma gondii (Q8MXA5), Toxoplasma gondii
Manually annotated by BRENDA team
Adama, C.; Bernard, S.; Brice, B.; Felix, Y.; Joseph, D.
Optimization of biomass and dihydroorotase (DHOase) production by Saccharomyces cerevisiae MNJ3 (pMNJ1)
Afr. J. Biotechnol.
8
037-041
2009
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team