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Reference on EC 3.5.1.B15 - pyrazinamidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fyfe, P.; Rao, V.; Zemla, A.; Cameron, S.; Hunter, W.
Specificity and mechanism of Acinetobacter baumanii nicotinamidase: Implications for activation of the front-line tuberculosis drug pyrazinamide
Angew. Chem. Int. Ed. Engl.
48
9176-9179
2009
Acinetobacter baumannii
Manually annotated by BRENDA team
Stekhanova, T.N.; Bezsudnova, E.Y.; Mardanov, A.V.; Osipov, E.M.; Ravin, N.V.; Skryabin, K.G.; Popov, V.O.
Nicotinamidase from the thermophilic archaeon Acidilobus saccharovorans: structural and functional characteristics
Biochemistry
79
54-61
2014
Acidilobus saccharovorans (D9Q1R5)
Manually annotated by BRENDA team
Zhang, J.L.; Zheng, Q.C.; Li, Z.Q.; Zhang, H.X.
Molecular dynamics simulations suggest ligands binding to nicotinamidase/pyrazinamidase
PLoS ONE
7
e39546
2012
Acinetobacter baumannii (B0VA03)
Manually annotated by BRENDA team
Rueda, D.; Sheen, P.; Gilman, R.H.; Bueno, C.; Santos, M.; Pando-Robles, V.; Batista, C.V.; Zimic, M.
Nicotinamidase/pyrazinamidase of Mycobacterium tuberculosis forms homo-dimers stabilized by disulfide bonds
Tuberculosis
94
644-648
2014
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Manually annotated by BRENDA team
Du, X.; Wang, W.; Kim, R.; Yakota, H.; Nguyen, H.; Kim, S.H.
Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii
Biochemistry
40
14166-14172
2001
Pyrococcus horikoshii (O58727), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (O58727)
Manually annotated by BRENDA team
Shang, F.; Chen, J.; Wang, L.; Jin, L.; Zou, L.; Bu, T.; Dong, Y.; Ha, N.C.; Nam, K.H.; Quan, C.; Xu, Y.
Crystal structure of the nicotinamidase/pyrazinamidase PncA from Bacillus subtilis
Biochem. Biophys. Res. Commun.
503
2906-2911
2018
Bacillus subtilis
Manually annotated by BRENDA team
Zapata-Perez, R.; Garcia-Saura, A.G.; Jebbar, M.; Golyshin, P.N.; Sanchez-Ferrer, A.
Combined whole-cell high-throughput functional screening for identification of new nicotinamidases/pyrazinamidases in metagenomic/polygenomic libraries
Front. Microbiol.
7
1915
2016
uncultured bacterium
Manually annotated by BRENDA team
Ramirez-Busby, S.M.; Valafar, F.
Systematic review of mutations in pyrazinamidase associated with pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates
Antimicrob. Agents Chemother.
59
5267-5277
2015
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Vats, C.; Dhanjal, J.; Goyal, S.; Gupta, A.; Bharadvaja, N.; Grover, A.
Mechanistic analysis elucidating the relationship between Lys96 mutation in Mycobacterium tuberculosis pyrazinamidase enzyme and pyrazinamide susceptibility
BMC Genomics
16(Suppl 2)
S14
2015
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Rasool, N.; Husssain, W.; Khan, Y.D.
Revelation of enzyme activity of mutant pyrazinamidases from Mycobacterium tuberculosis upon binding with various metals using quantum mechanical approach
Comput. Biol. Chem.
83
107108
2019
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Pazhang, M.; Mardi, N.; Mehrnejad, F.; Chaparzadeh, N.
The combinatorial effects of osmolytes and alcohols on the stability of pyrazinamidase methanol affects the enzyme stability through hydrophobic interactions and hydrogen bonds
Int. J. Biol. Macromol.
108
1339-1347
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Khajehzadeh, M.; Mehrnejad, F.; Pazhang, M.; Doustdar, F.
Effects of sorbitol and glycerol on the structure, dynamics, and stability of Mycobacterium tuberculosis pyrazinamidase
Int. J. Mycobacteriol.
5 Suppl 1
S138-S139
2016
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Rueda, D.; Bernard, C.; Gandy, L.; Capton, E.; Boudjelloul, R.; Brossier, F.; Veziris, N.; Zimic, M.; Sougakoff, W.
Estimation of pyrazinamidase activity using a cell-free in vitro synthesis of pnca and its association with pyrazinamide susceptibility in Mycobacterium tuberculosis
Int. J. Mycobacteriol.
7
16-25
2018
Mycobacterium tuberculosis variant bovis, Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Khan, M.T.; Malik, S.I.
Structural dynamics behind variants in pyrazinamidase and pyrazinamide resistance
J. Biomol. Struct. Dyn.
38
3003-3017
2020
Mycobacterium tuberculosis (A0A2Z5CVM9), Mycobacterium tuberculosis
Manually annotated by BRENDA team
Esmaeeli, R.; Mehrnejad, F.; Mir-Derikvand, M.; Gopalpoor, N.
Computational insights into pH-dependence of structure and dynamics of pyrazinamidase A comparison of wild type and mutants
J. Cell. Biochem.
120
2502-2514
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Khan, M.; Junaid, M.; Mao, X.; Wang, Y.; Hussain, A.; Malik, S.; Wei, D.
Pyrazinamide resistance and mutations L19R, R140H, and E144K in pyrazinamidase of Mycobacterium tuberculosis
J. Cell. Biochem.
120
7154-7166
2019
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Junaid, M.; Khan, M.T.; Malik, S.I.; Wei, D.Q.
Insights into the mechanisms of the pyrazinamide resistance of three pyrazinamidase mutants N11K, P69T, and D126N
J. Chem. Inf. Model.
59
498-508
2019
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Aono, A.; Chikamatsu, K.; Yamada, H.; Igarashi, Y.; Murase, Y.; Takaki, A.; Mitarai, S.
A simplified pyrazinamidase test for pyrazinamide drug susceptibility in Mycobacterium tuberculosis
J. Microbiol. Methods
154
52-54
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Khadem-Maaref, M.; Mehrnejad, F.; Phirouznia, A.
Effects of metal-ion replacement on pyrazinamidase activity a quantum mechanical study
J. Mol. Graph. Model.
73
24-29
2017
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Rasool, N.; Iftikhar, S.; Amir, A.; Hussain, W.
Structural and quantum mechanical computations to elucidate the altered binding mechanism of metal and drug with pyrazinamidase from Mycobacterium tuberculosis due to mutagenicity
J. Mol. Graph. Model.
80
126-131
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team
Prabhavadhni, A.; Gorai, B.; Visalakshi, P.; Sivaraman, T.
In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium
J. Pharm. Sci. Res.
7
416-419
2015
Mycobacterium marinum (A0A3E2MTZ2), Mycobacteroides abscessus (B1MLY1), Mycobacterium kansasii (O07691), Mycobacterium avium (P94914), Mycolicibacterium smegmatis (Q9ZF59), Mycobacterium tuberculosis variant bovis (U5TP36), Mycobacteroides abscessus JCM 13569 (B1MLY1), Mycobacteroides abscessus CIP 104536 (B1MLY1), Mycobacteroides abscessus DSM 44196 (B1MLY1), Mycobacteroides abscessus ATCC 19977 (B1MLY1), Mycobacteroides abscessus NCTC 13031 (B1MLY1), Mycobacteroides abscessus TMC 1543 (B1MLY1)
-
Manually annotated by BRENDA team
Doustdar, F.; Pazhang, M.; Mehrnejad, F.; Safarzadeh, M.; Rabiei, D.; Chaparzadeh, N.; Falahati, H.; Mir-Derikvand, M.
Biochemical characterization and computational identification of Mycobacterium tuberculosis pyrazinamidase in some pyrazinamide-resistant isolates of Iran
Protein J.
34
181-192
2015
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Ahmadi, A.; Nazari, R.; Arjomandzadegan, M.; Zolfaghari, M.R.; Vahidi, V.; Poolad, T.; Kahbazi, M.; Sadrnia, M.; Tousheh, M.; Rafiee, P.
Insights into pyrazinamidase and DNA gyrase protein structures in resistant and susceptible clinical isolates of Mycobacterium tuberculosis
Tanaffos
15
147-153
2016
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65)
Manually annotated by BRENDA team