Reference on EC 3.5.1.92 - pantetheine hydrolase
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Dupre, S.; Chiaraluce, R.; Nardini, M.; Cannella, C.; Ricci, G.; Cavallini, D.
Continuous spectrophotometric assay of pantetheinase activity
Anal. Biochem.
142
175-181
1984
Equus caballus
Ricci, G.; Nardini, M.; Chiaraluce, R.; Dupre, S.; Cavallini, D.
Interaction of pantetheinase with sulfhydryl reagents and disulfides
Biochim. Biophys. Acta
870
82-91
1986
Sus scrofa
Pitari, G.; Maurizi, G.; Ascenzi, P.; Ricci, G.; Dupre, S.
A kinetic study on pantetheinase inhibition by disulfides
Eur. J. Biochem.
226
81-86
1994
Sus scrofa
Maras, B.; Barra, D.; Dupre, S.; Pitari, G.
Is pantetheinase the actual identity of mouse and human vanin-1 proteins?
FEBS Lett.
461
149-152
1999
BRENDA: Mus musculus, Sus scrofa
Textmining: Homo sapiens
Pitari, G.; Malergue, F.; Martin, F.; Philippe, J.M.; Massucci, M.T.; Chabret, C.; Maras, B.; Dupre, S.; Naquet, P.; Galland, F.
Pantetheinase activity of membrane-bound vanin-1: lack of free cysteamine in tissues of vanin-1 deficient mice
FEBS Lett.
483
149-154
2000
BRENDA: Mus musculus
Textmining: Mus sp.
Bowles, J.; Bullejos, M.; Koopman, P.
A subtractive gene expression screen suggests a role for vanin-1 in testis development in mice
Genesis
27
124-135
2000
BRENDA: Mus musculus
Textmining: Mus sp.
Aurrand-Lions, M.; Galland, F.; Bazin, H.; Zakharyev, V.M.; Imhof, B.A.; Naquet, P.
Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing
Immunity
5
391-405
1996
BRENDA: Mus musculus
Textmining: Homo sapiens
Martin, F.; Malergue, F.; Pitari, G.; Philippe, J.M.; Philips, S.; Chabret, C.; Granjeaud, S.; Mattei, M.G.; Mungall, A.J.; Naquet, P.; Galland, F.
Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes
Immunogenetics
53
296-306
2001
BRENDA: Mus musculus
Textmining: Homo sapiens
Wittwer, C.T.; Burkhard, D.; Ririe, K.; Rasmussen, R.; Brown, J.; Wyse, B.W.; Hansen, R.G.
Purification and properties of a pantetheine-hydrolyzing enzyme from pig kidney
J. Biol. Chem.
258
9733-9738
1983
Sus scrofa
Wilson, M.J.; Jeyasuria, P.; Parker, K.L.; Koopman, P.
The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development
J. Biol. Chem.
280
5917-5923
2005
BRENDA: Mus musculus
Textmining: Mus sp.
Martin, F.; Penet, M.F.; Malergue, F.; Lepidi, H.; Dessein, A.; Galland, F.; de Reggi, M.; Naquet, P.; Gharib, B.
Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores
J. Clin. Invest.
113
591-597
2004
Mus musculus
Calvino, J.A.; Barcia, R.
Purification and properties of pantetheinase from pig kidney
J. Food Biochem.
26
103-118
2002
Sus scrofa
Wittwer, C.T.; Wyse, B.W.; Hansen, R.G.
Enzymic hydrolysis of pantetheine
Methods Enzymol.
122
36-43
1986
Sus scrofa
Dupre, S.; Cavallini, D.
Purification and properties of pantetheinase from horse kidney
Methods Enzymol.
62
262-267
1979
Equus caballus
Berruyer, C.; Martin, F.M.; Castellano, R.; Macone, A.; Malergue, F.; Garrido-Urbani, S.; Millet, V.; Imbert, J.; Dupre, S.; Pitari, G.; Naquet, P.; Galland, F.
Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress
Mol. Cell. Biol.
24
7214-7224
2004
BRENDA: Mus musculus
Textmining: Mus sp.
Johnson, K.A.; Yao, W.; Lane, N.E.; Naquet, P.; Terkeltaub, R.A.
Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank mice
Am. J. Pathol.
172
440-453
2008
BRENDA: Mus musculus
Textmining: Mus sp.
Roisin-Bouffay, C.; Castellano, R.; Valero, R.; Chasson, L.; Galland, F.; Naquet, P.
Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes
Diabetologia
51
1192-1201
2008
BRENDA: Mus musculus
Textmining: Mus sp.
Meghari, S.; Berruyer, C.; Lepidi, H.; Galland, F.; Naquet, P.; Mege, J.L.
Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection
Eur. J. Immunol.
37
24-32
2007
BRENDA: Mus musculus
Textmining: Coxiella burnetii, Mus sp.
Berruyer, C.; Pouyet, L.; Millet, V.; Martin, F.M.; LeGoffic, A.; Canonici, A.; Garcia, S.; Bagnis, C.; Naquet, P.; Galland, F.
Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity
J. Exp. Med.
203
2817-2827
2006
Mus musculus
Nitto, T.; Inoue, T.; Node, K.
Alternative spliced variants in the pantetheinase family of genes expressed in human neutrophils
Gene
426
57-64
2008
BRENDA: Homo sapiens (O95497), Homo sapiens (O95498), Homo sapiens (Q9NY84), Homo sapiens
Textmining: Mus musculus
Jansen, P.A.; Kamsteeg, M.; Rodijk-Olthuis, D.; van Vlijmen-Willems, I.M.; de Jongh, G.J.; Bergers, M.; Tjabringa, G.S.; Zeeuwen, P.L.; Schalkwijk, J.
Expression of the Vanin Gene Family in Normal and Inflamed Human Skin: Induction by Proinflammatory Cytokines
J. Invest. Dermatol.
129
2167-2174
2009
BRENDA: Homo sapiens (O95497), Homo sapiens (O95498), Homo sapiens (Q9NY84), Homo sapiens
Textmining: Mus musculus
Ruan, B.H.; Cole, D.C.; Wu, P.; Quazi, A.; Page, K.; Wright, J.F.; Huang, N.; Stock, J.R.; Nocka, K.; Aulabaugh, A.; Krykbaev, R.; Fitz, L.J.; Wolfman, N.M.; Fleming, M.L.
A fluorescent assay suitable for inhibitor screening and vanin tissue quantification
Anal. Biochem.
399
284-292
2010
Homo sapiens, Mus musculus
Kaskow, B.J.; Michael Proffit, J.; Blangero, J.; Moses, E.K.; Abraham, L.J.
Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases
Biochem. Biophys. Res. Commun.
417
653-658
2012
Homo sapiens, Mus musculus
Zhang, B.; Lo, C.; Shen, L.; Sood, R.; Jones, C.; Cusmano-Ozog, K.; Park-Snyder, S.; Wong, W.; Jeng, M.; Cowan, T.; Engleman, E.G.; Zehnder, J.L.
The role of vanin-1 and oxidative stress-related pathways in distinguishing acute and chronic pediatric ITP
Blood
117
4569-4579
2011
Homo sapiens
Hosohata, K.; Ando, H.; Fujiwara, Y.; Fujimura, A.
Vanin-1: a potential biomarker for nephrotoxicant-induced renal injury
Toxicology
290
82-88
2011
BRENDA: Homo sapiens, Rattus norvegicus
Textmining: Rattus
Jansen, P.A.; van Diepen, J.A.; Ritzen, B.; Zeeuwen, P.L.; Cacciatore, I.; Cornacchia, C.; van Vlijmen-Willems, I.M.; de Heuvel, E.; Botman, P.N.; Blaauw, R.H.; Hermkens, P.H.; Rutjes, F.P.; Schalkwijk, J.
Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease
ACS Chem. Biol.
8
530-534
2013
BRENDA: Rattus norvegicus (Q4KLZ0)
Textmining: Rattus
Boersma, Y.L.; Newman, J.; Adams, T.E.; Cowieson, N.; Krippner, G.; Bozaoglu, K.; Peat, T.S.
The structure of vanin 1: a key enzyme linking metabolic disease and inflammation
Acta Crystallogr. Sect. D
70
3320-3329
2014
Homo sapiens (O95497), Homo sapiens
Sayasith, K.; Sirois, J.; Lussier, J.G.
Expression, regulation, and promoter activation of vanin-2 (VNN2) in bovine follicles prior to ovulation
Biol. Reprod.
89
98
2013
Bos taurus (A5D9D1), Bos taurus, Bos taurus Holstein (A5D9D1)
Hosohata, K.; Ando, H.; Fujimura, A.
Early detection of renal injury using urinary vanin-1 in rats with experimental colitis
J. Appl. Toxicol.
34
184-190
2014
BRENDA: Rattus norvegicus (Q4KLZ0), Rattus norvegicus, Rattus norvegicus Wistar (Q4KLZ0)
Textmining: Rattus
Hosohata, K.; Ando, H.; Fujimura, A.
Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury
J. Pharmacol. Exp. Ther.
341
656-662
2012
BRENDA: Rattus norvegicus (Q4KLZ0), Rattus norvegicus Wistar (Q4KLZ0)
Textmining: Rattus, animal
Wang, Y.J.; Tayo, B.O.; Bandyopadhyay, A.; Wang, H.; Feng, T.; Franceschini, N.; Tang, H.; Gao, J.; Sung, Y.J.; Sung, Y.J.; Elston, R.C.; Williams, S.M.; Cooper, R.S.; Mu, T.W.; Zhu, X.
The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function
PLoS Genet.
10
e1004641
2014
Homo sapiens (O95497)
Rommelaere, S.; Millet, V.; Rihet, P.; Atwell, S.; Helfer, E.; Chasson, L.; Beaumont, C.; Chimini, G.; Sambo, M.d.o. .R.; Viallat, A.; Penha-Goncalves, C.; Galland, F.; Naquet, P.
Serum pantetheinase/vanin levels regulate erythrocyte homeostasis and severity of malaria
Am. J. Pathol.
185
3039-3052
2015
Homo sapiens (O95497), Homo sapiens, Mus musculus (Q9Z0K8), Mus musculus, Mus musculus C57BL/6 (Q9Z0K8)
Lin, Y.; Gao, Y.; Ma, Z.; Li, Z.; Tang, C.; Qin, X.; Zhang, Z.; Wang, G.; Du, L.; Li, M.
Bioluminescent probe for detection of starvation-induced pantetheinase upregulation
Anal. Chem.
90
9545-9550
2018
BRENDA: Mus musculus (Q9Z0K8)
Textmining: animal
Yamashita, N.; Yashiro, M.; Ogawa, H.; Namba, H.; Nosaka, N.; Fujii, Y.; Morishima, T.; Tsukahara, H.; Yamada, M.
Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells
Biochem. Biophys. Res. Commun.
489
466-471
2017
Homo sapiens (O95497), Homo sapiens
Ferreira, D.W.; Naquet, P.; Manautou, J.E.
Influence of vanin-1 and catalytic products in liver during normal and oxidative stress conditions
Curr. Med. Chem.
22
2407-2416
2015
Mus musculus (Q9Z0K8), Mus musculus C57BL/6 (Q9Z0K8)
Bartucci, R.; Salvati, A.; Olinga, P.; Boersma, Y.L.
Vanin 1 its physiological function and role in diseases
Int. J. Mol. Sci.
20
3891
2019
Homo sapiens (O95497)
Bartucci, R.; Salvati, A.; Olinga, P.; Boersma, Y.L.
Vanin 1 its physiological function and role in diseases
Int. J. Mol. Sci.
20
E3891
2019
Rattus norvegicus, Sus scrofa (Q9BDJ5), Mus musculus (Q9Z0K8)
Kavian, N.; Mehlal, S.; Marut, W.; Servettaz, A.; Giessner, C.; Bourges, C.; Nicco, C.; Chereau, C.; Lemarechal, H.; Dutilh, M.F.; Cerles, O.; Guilpain, P.; Vuiblet, V.; Chouzenoux, S.; Galland, F.; Quere, I.; Weill, B.; Naquet, P.; Batteux, F.
Imbalance of the vanin-1 pathway in systemic sclerosis
J. Immunol.
197
3326-3335
2016
BRENDA: Mus musculus (Q9Z0K8), Mus musculus BALB/c (Q9Z0K8)
Textmining: Homo sapiens, Mus sp.
Giessner, C.; Millet, V.; Mostert, K.J.; Gensollen, T.; Vu Manh, T.P.; Garibal, M.; Dieme, B.; Attaf-Bouabdallah, N.; Chasson, L.; Brouilly, N.; Laprie, C.; Lesluyes, T.; Blay, J.Y.; Shintu, L.; Martin, J.C.; Strauss, E.; Galland, F.; Naquet, P.
Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity
Life Sci. Alliance
1
e201800073
2018
Mus musculus (Q9Z0K8)
Grimmond, S; Van Hateren, N; Siggers, P; Arkell, R; Larder, R; Soares, MB; de Fatima Bonaldo, M; Smith, L; Tymowska-Lalanne, Z; Wells, C; Greenfield, A
Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.
Hum Mol Genet
9
1553-60
2000
Mus musculus
Leuner, B; Ruhs, S; Brmme, HJ; Bierhaus, A; Sel, S; Silber, RE; Somoza, V; Simm, A; Nass, N
RAGE-dependent activation of gene expression of superoxide dismutase and vanins by AGE-rich extracts in mice cardiac tissue and murine cardiac fibroblasts.
Food Funct
2012
Mus musculus, Mus sp., Metazoa
Di Leandro, L; Maras, B; Schininà, ME; Dupré, S; Koutris, I; Martin, FM; Naquet, P; Galland, F; Pitari, G
Cystamine restores GSTA3 levels in Vanin-1 null mice.
Free Radic Biol Med
44
1088-96
2008
Mus sp., Mus musculus, Metazoa
Galland, F; Malergue, F; Bazin, H; Mattei, MG; Aurrand-Lions, M; Theillet, C; Naquet, P
Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6.
Genomics
53
203-13
1998
Homo sapiens, Mus musculus
Granjeaud, S; Naquet, P; Galland, F
An ESTs description of the new Vanin gene family conserved from fly to human.
Immunogenetics
49
964-72
1999
Drosophila, Homo sapiens, Mus musculus
Huang, J; Takeda, Y; Watanabe, T; Sendo, F
A sandwich ELISA for detection of soluble GPI-80, a glycosylphosphatidyl-inositol (GPI)-anchored protein on human leukocytes involved in regulation of neutrophil adherence and migration--its release from activated neutrophils and presence in synovial fluid of rheumatoid arthritis patients.
Microbiol Immunol
45
467-71
2001
Homo sapiens, Oryctolagus cuniculus
Koike, S; Takeda, Y; Hozumi, Y; Okazaki, S; Aoyagi, M; Sendo, F
Immunohistochemical localization in human tissues of GPI-80, a novel glycosylphosphatidyl inositol-anchored protein that may regulate neutrophil extravasation.
Cell Tissue Res
307
91-9
2002
Homo sapiens
Nitto, T; Araki, Y; Takeda, Y; Sendo, F
Pharmacological analysis for mechanisms of GPI-80 release from tumour necrosis factor-alpha-stimulated human neutrophils.
Br J Pharmacol
137
353-60
2002
Homo sapiens
Sendo, D; Takeda, Y; Ishikawa, H; Sendo, F; Araki, Y
Localization of GPI-80, a beta2-integrin-associated glycosylphosphatidyl-inositol anchored protein, on strongly CD14-positive human monocytes.
Immunobiology
207
217-21
2003
Homo sapiens
Dock, G
JULIUS PAGEL AND THE PAGEL COLLECTION OF BOOKS ON THE HISTORY OF MEDICINE IN THE WASHINGTON UNIVERSITY MEDICAL SCHOOL.
Bull Med Libr Assoc
3
21-5
1913
collection
Nitto, T; Takeda, Y; Yoshitake, H; Sendo, F; Araki, Y
Structural divergence of GPI-80 in activated human neutrophils.
Biochem Biophys Res Commun
359
227-33
2007
Homo sapiens
Trimble, V
Evolutionary Phenomena in Galaxies. J. E. Beckman and B. E. J. Pagel, Eds. Cambridge University Press, New York, 1989. viii, 468 pp., illus. $69.50. Based on an institute, Tenerife, Canary Islands.
Science
249
80
1990
Serinus canaria
Min-Oo, G; Ayi, K; Bongfen, SE; Tam, M; Radovanovic, I; Gauthier, S; Santiago, H; Rothfuchs, AG; Roffê, E; Sher, A; Mullick, A; Fortin, A; Stevenson, MM; Kain, KC; Gros, P
Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium.
Exp Parasitol
2010
Plasmodium, Plasmodium chabaudi AS, Plasmodium chabaudi, Mus sp.
Pagel, M; Krakauer, DC
Is the propagation of prion molecules in different hosts an example of lamarckian inheritance? Reply from M. Pagel and D.C. Krakauer.
Trends Ecol Evol
12
194
1997
prion
Fugmann, T; Borgia, B; Rvsz, C; God, M; Forsblom, C; Hamar, P; Holthfer, H; Neri, D; Roesli, C
Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy.
Kidney Int
80
272-81
2011
Rattus, Homo sapiens
Spry, C; Macuamule, C; Lin, Z; Virga, KG; Lee, RE; Strauss, E; Saliba, KJ
Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.
PLoS One
8
e54974
2013
Plasmodium falciparum
Elsalakawy, WA; Ali, MA; Hegazy, MG; Farweez, BA
Value of vanin-1 assessment in adult patients with primary immune thrombocytopenia.
Platelets
2013
Homo sapiens
Jansen, PA; Hermkens, PH; Zeeuwen, PL; Botman, PN; Blaauw, RH; Burghout, P; van Galen, PM; Mouton, JW; Rutjes, FP; Schalkwijk, J
Combination of Pantothenamides with Vanin Inhibitors as a Novel Antibiotic Strategy against Gram-Positive Bacteria.
Antimicrob Agents Chemother
57
4794-800
2013
Firmicutes, Staphylococcus epidermidis, Streptococcus, Streptococcus pneumoniae
At??, O; Aksoy, H; Kele?, M; Gm?dere, M
Serum vanin-1 levels in renal transplant patients.
Exp Clin Transplant
12
113-6
2014
Homo sapiens
Latre de Late, P; Wakil, AE; Jarjat, M; de Krijger, RR; Heckert, LL; Naquet, P; Lalli, E
Vanin-1 inactivation antagonizes the development of adrenocortical neoplasia in Sf-1 transgenic mice.
Endocrinology
en20141088
2014
Mus musculus
Ben, Dde C; Vanin, SA
A new troglobitic species of Coarazuphium Gnaspini, Vanin & Godoy (Coleoptera, Carabidae, Zuphiini) from a cave in Paran State, Southern Brazil.
Zootaxa
3779
288-96
2014
Carabidae
Vanin, SA; De Medeiros, BA
A new species of Sicoderus Vanin from Bolivia (Coleoptera: Curculionidae: Curculioninae: Otidocephalini).
Zootaxa
3734
81-5
2013
Curculionidae, Curculioninae, Sicoderus
Prashad, SL; Calvanese, V; Yao, CY; Kaiser, J; Wang, Y; Sasidharan, R; Crooks, G; Magnusson, M; Mikkola, HK
GPI-80 defines self-renewal ability in hematopoietic stem cells during human development.
Cell Stem Cell
16
80-7
2015
Homo sapiens, Mus sp.
Camplin, T
Wired for Culture: Origins of the Human Social Mind Mark Pagel , Wired for Culture: Origins of the Human Social Mind ( New York : W.W. Norton & Company , 2012 ), 432 pages. ISBN: 978-0393344202 . Softcover $18.95 .
Politics Life Sci
34
113-4
2015
Homo sapiens
Ferreira, DW; Goedken, MJ; Rommelaere, S; Chasson, L; Galland, F; Naquet, P; Manautou, JE
Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses.
Biochim Biophys Acta
1862
662-9
2016
Mus sp.
van Diepen, JA; Jansen, PA; Ballak, DB; Hijmans, A; Rutjes, FP; Tack, CJ; Netea, MG; Schalkwijk, J; Stienstra, R
Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes.
Sci Rep
6
21906
2016
animal, Mus sp., Rattus, Metazoa
Li, Y; Wang, X; Yu, J; Shao, F; Zhang, Y; Lu, X; Gu, Z
MiR-122 targets the vanin 1 gene to regulate its expression in chickens.
Poult Sci
95
1145-50
2016
Gallus gallus
Wedel, J; Jansen, PA; Botman, PN; Rutjes, FP; Schalkwijk, J; Hillebrands, JL
Pharmacological Inhibition of Vanin Activity Attenuates Transplant Vasculopathy in Rat Aortic Allografts.
Transplantation
2016
Rattus, Mus sp.
Hosohata, K; Washino, S; Kubo, T; Natsui, S; Fujisaki, A; Kurokawa, S; Ando, H; Fujimura, A; Morita, T
Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinoma.
Toxicology
359-360
71-5
2016
Homo sapiens
Matsuoka, Y; Sumide, K; Kawamura, H; Nakatsuka, R; Fujioka, T; Sonoda, Y
GPI-80 expression highly purifies human cord blood-derived primitive CD34-negative hematopoietic stem cells.
Blood
2016
Homo sapiens
Sobolesky, P; Parry, C; Boxall, B; Wells, R; Venn-Watson, S; Janech, MG
Proteomic Analysis of Non-depleted Serum Proteins from Bottlenose Dolphins Uncovers a High Vanin-1 Phenotype.
Sci Rep
6
33879
2016
Platanistidae, Homo sapiens, dolphin
Anderson, RS
The genus Sicoderus Vanin 1986 (Coleoptera: Curculionidae: Curculioninae: Erodiscini) in the West Indies.
Zootaxa
4497
301-345
2018
Curculionidae, Curculioninae, Sicoderus
Hosohata, K; Jin, D; Takai, S; Iwanaga, K
Vanin-1 in Renal Pelvic Urine Reflects Kidney Injury in a Rat Model of Hydronephrosis.
Int J Mol Sci
19
2018
Rattus
Hosohata, K; Jin, D; Takai, S; Iwanaga, K
Involvement of Vanin-1 in Ameliorating Effect of Oxidative Renal Tubular Injury in Dahl-Salt Sensitive Rats.
Int J Mol Sci
20
2019
Rattus
Zhang, Y; Qin, X
Commentary: Urinary vanin-1 and chronic kidney disease in hypertensive patients.
J Clin Hypertens (Greenwich)
2020
Homo sapiens
Hosohata, K; Matsuoka, H; Iwanaga, K; Kumagai, E
Urinary vanin-1 associated with chronic kidney disease in hypertensive patients: A pilot study.
J Clin Hypertens (Greenwich)
22
1458-1465
2020
Homo sapiens, Rattus
Gurung, AB; Bhutia, JT; Bhattacharjee, A
High-throughput virtual screening of novel potent inhibitor(s) for Human Vanin-1 enzyme.
J Biomol Struct Dyn
1-16
2020
Homo sapiens
Lu, H; Zhang, A; Wen, D; Du, J; Sun, J; Qiao, L; Du, D; Gu, W; Jiang, J
Plasma Vanin-1 as a Novel Biomarker of Sepsis for Trauma Patients: A Prospective Multicenter Cohort Study.
Infect Dis Ther
10
739-751
2021
Homo sapiens
Krzemie?, G; Pa?czyk-Tomaszewska, M; Grska, E; Szmigielska, A
Urinary vanin-1 for predicting acute pyelonephritis in young children with urinary tract infection: a pilot study.
Biomarkers
26
318-324
2021
Homo sapiens
Hosohata, K; Matsuoka, H; Kumagai, E
Association of urinary vanin-1 with kidney function decline in hypertensive patients.
J Clin Hypertens (Greenwich)
23
1316-1321
2021
Homo sapiens, Rattus
Yang, Y; Hu, Y; Shi, W; Ma, H
A near-infrared fluorescence probe for imaging of pantetheinase in cells and mice in vivo.
Chem Sci
11
12802-12806
2020
Mus sp., Mus musculus
Calvino JA;Barcia R
Purification and properties of pantetheinase from pig kidney.
Journal of food biochemistry
26
103-118
2002
Sus scrofa
Kulohoma, BW; Marriage, F; Vasieva, O; Mankhambo, L; Nguyen, K; Molyneux, ME; Molyneux, EM; Day, PJR; Carrol, ED
Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study.
BMJ Paediatr Open
1
e000092
2017
Human immunodeficiency virus 1
Schalkwijk, J; Allman, EL; Jansen, PAM; de Vries, LE; Verhoef, JMJ; Jackowski, S; Botman, PNM; Beuckens-Schortinghuis, CA; Koolen, KMJ; Bolscher, JM; Vos, MW; Miller, K; Reeves, SA; Pett, H; Trevitt, G; Wittlin, S; Scheurer, C; Sax, S; Fischli, C; Angulo-Barturen, I; Jimnez-Diaz, MB; Josling, G; Kooij, TWA; Bonnert, R; Campo, B; Blaauw, RH; Rutjes, FPJT; Sauerwein, RW; Llins, M; Hermkens, PHH; Dechering, KJ
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.
Sci Transl Med
11
2019
Mus musculus
Frank, O; Brors, B; Fabarius, A; Li, L; Haak, M; Merk, S; Schwindel, U; Zheng, C; Müller, MC; Gretz, N; Hehlmann, R; Hochhaus, A; Seifarth, W
Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients.
Leukemia
20
1400-7
2006
Homo sapiens
Kusebauch, U; Hernndez-Castellano, LE; Bislev, SL; Moritz, RL; Rntved, CM; Bendixen, E
Selected reaction monitoring mass spectrometry of mastitis milk reveals pathogen-specific regulation of bovine host response proteins.
J Dairy Sci
101
6532-6541
2018
Firmicutes
Oraby, MA; El-Yamany, MF; Safar, MM; Assaf, N; Ghoneim, HA
Amelioration of Early Markers of Diabetic Nephropathy by Linagliptin in Fructose-Streptozotocin-Induced Type 2 Diabetic Rats.
Nephron
1-14
2019
Rattus
Ijssennagger, N; de Wit, N; Mller, M; van der Meer, R
Dietary Heme-Mediated PPAR? Activation Does Not Affect the Heme-Induced Epithelial Hyperproliferation and Hyperplasia in Mouse Colon.
PLoS One
7
e43260
2012
Mus sp.
Suzuki, K; Watanabe, T; Sakurai, S; Ohtake, K; Kinoshita, T; Araki, A; Fujita, T; Takei, H; Takeda, Y; Sato, Y; Yamashita, T; Araki, Y; Sendo, F
A novel glycosylphosphatidyl inositol-anchored protein on human leukocytes: a possible role for regulation of neutrophil adherence and migration.
J Immunol
162
4277-84
1999
Homo sapiens, Mus sp.
Yu, Y; Araki, Y; Sendo, F
Tyrosine phosphorylation of a 34-kDa protein induced by cross-linking a novel glycosylphosphatidylinositol-anchored glycoprotein (GPI-80) on human neutrophils that may regulate their adherence and migration.
IUBMB Life
49
43-7
2000
Homo sapiens
Marquis, JF; Gros, P
Genetic analysis of resistance to infections in mice: A/J meets C57BL/6J.
Curr Top Microbiol Immunol
321
27-57
2008
Plasmodium
Helms, LR; Swenson, RP
Cloning and characterization of the flavodoxin gene from Desulfovibrio desulfuricans.
Biochim Biophys Acta
1089
417-9
1991
Desulfovibrio vulgaris
Helms, LR; Krey, GD; Swenson, RP
Identification, sequence determination, and expression of the flavodoxin gene from Desulfovibrio salexigens.
Biochem Biophys Res Commun
168
809-17
1990
Desulfovibrio vulgaris, Maridesulfovibrio salexigens
Kallós, P; Kallós, L
Experimental asthma in guinea pigs revisited.
Int Arch Allergy Appl Immunol
73
77-85
1984
Cavia
Sasaki, H; Ide, N; Sendo, F; Takeda, Y; Adachi, M; Fukai, I; Fujii, Y
Glycosylphosphatidyl inositol-anchored protein (GPI-80) gene expression is correlated with human thymoma stage.
Cancer Sci
94
809-13
2003
Mus musculus
Göring, HH; Curran, JE; Johnson, MP; Dyer, TD; Charlesworth, J; Cole, SA; Jowett, JB; Abraham, LJ; Rainwater, DL; Comuzzie, AG; Mahaney, MC; Almasy, L; Maccluer, JW; Kissebah, AH; Collier, GR; Moses, EK; Blangero, J
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes.
Nat Genet
39
1208-16
2007
Homo sapiens
Lurie, MB
THE CORRELATION BETWEEN THE HISTOLOGICAL CHANGES AND THE FATE OF LIVING TUBERCLE BACILLI IN THE ORGANS OF TUBERCULOUS RABBITS.
J Exp Med
55
31-54
1932
animal
Min-Oo, G; Gros, P
Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria.
Mamm Genome
2011
Mus musculus
Ball, GE; Shpeley, D
Western Hemisphere Zuphiini: descriptions of Coarazuphium whiteheadi, new species, and Zuphioides, new genus, and classification of the genera (Coleoptera, Carabidae).
Zookeys
17-54
2013
Zuphium, Parazuphium
Hosohata, K; Ando, H; Takeshita, Y; Misu, H; Takamura, T; Kaneko, S; Fujimura, A
Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats.
Diab Vasc Dis Res
11
243-250
2014
Rattus
Pellegrini, TG; Ferreira, RL
Ultrastructural analysis and polymorphisms in Coarazuphium caatinga (Coleoptera: Carabidae: Zuphiini), a new Brazilian troglobitic beetle.
Zootaxa
3765
526-40
2014
Coleoptera
Ivanovs, A; Medvinsky, A
In search of human hematopoietic stem cell identity.
Cell Stem Cell
16
5-6
2015
Homo sapiens
Hosohata, K; Yoshioka, D; Tanaka, A; Ando, H; Fujimura, A
Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake.
Hypertens Res
39
19-26
2016
Metazoa
Moradin, N; Torre, S; Gauthier, S; Tam, M; Hawari, J; Vandercruyssen, K; De Spiegeleer, B; Fortin, A; Stevenson, MM; Gros, P
Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria.
Malar J
15
260
2016
Mus sp.
Washino, S; Hosohata, K; Jin, D; Takai, S; Miyagawa, T
Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats.
Clin Exp Pharmacol Physiol
45
261-268
2018
Rattus
Oraby, MA; El-Yamany, MF; Safar, MM; Assaf, N; Ghoneim, HA
Dapagliflozin attenuates early markers of diabetic nephropathy in fructose-streptozotocin-induced diabetes in rats.
Biomed Pharmacother
109
910-920
2019
Rattus
Grabowski, JM; Nilsson, OR; Fischer, ER; Long, D; Offerdahl, DK; Park, Y; Scott, DP; Bloom, ME
Dissecting Flavivirus Biology in Salivary Gland Cultures from Fed and Unfed Ixodes scapularis (Black-Legged Tick).
MBio
10
2019
Ixodes scapularis
Xing, Y; Wei, H; Xiao, X; Chen, Z; Liu, H; Tong, X; Zhou, W
Methylated Vnn1 at promoter regions induces asthma occurrence via the PI3K/Akt/NF?B-mediated inflammation in the IUGR mice.
Biol Open
2020
Mus sp.
DE Medeiros, BAS; Vanin, SA
Systematic revision and morphological phylogenetic analysis ofAnchylorhynchus Schoenherr, 1836 (Coleoptera, Curculionidae: Derelomini).
Zootaxa
4839
zootaxa.4839.1.1
2020
Anchylorhynchus
Pett, HE; Jansen, PA; Hermkens, PH; Botman, PN; Beuckens-Schortinghuis, CA; Blaauw, RH; Graumans, W; van de Vegte-Bolmer, M; Koolen, KM; Rutjes, FP; Dechering, KJ; Sauerwein, RW; Schalkwijk, J
Novel pantothenate derivatives for anti-malarial chemotherapy.
Malar J
14
169
2015
Homo sapiens
Wittwer, CT; Schweitzer, C; Pearson, J; Song, WO; Windham, CT; Wyse, BW; Hansen, RG
Enzymes for liberation of pantothenic acid in blood: use of plasma pantetheinase.
Am J Clin Nutr
50
1072-8
1989
Homo sapiens, Sus scrofa
Pitari, G; Antonini, G; Mancini, R; Duprè, S
Thermal resistance of pantetheine hydrolase.
Biochim Biophys Acta
1298
31-6
1996
Sus scrofa
Pitari, G; D'Archivio, AA; Di Leandro, L; Antonini, G; Panatta, A; Tettamanti, E; Duprè, S; Malatesta, F
Conformational changes at the active site of pantetheine hydrolase during denaturation by guanidine hydrochloride.
J Protein Chem
18
785-9
1999
Electron
Dahlgren, C; Karlsson, A; Sendo, F
Neutrophil secretory vesicles are the intracellular reservoir for GPI-80, a protein with adhesion-regulating potential.
J Leukoc Biol
69
57-62
2001
Homo sapiens
Watanabe, T; Sendo, F
Physical association of beta 2 integrin with GPI-80, a novel glycosylphosphatidylinositol-anchored protein with potential for regulating adhesion and migration.
Biochem Biophys Res Commun
294
692-4
2002
Homo sapiens
Takeda, Y; Fu, J; Suzuki, K; Sendo, D; Nitto, T; Sendo, F; Araki, Y
Expression of GPI-80, a beta2-integrin-associated glycosylphosphatidylinositol-anchored protein, requires neutrophil differentiation with dimethyl sulfoxide in HL-60 cells.
Exp Cell Res
286
199-208
2003
Homo sapiens
Yoshitake, H; Takeda, Y; Nitto, T; Sendo, F; Araki, Y
GPI-80, a beta2 integrin associated glycosylphosphatidylinositol-anchored protein, concentrates on pseudopodia without association with beta2 integrin during neutrophil migration.
Immunobiology
208
391-9
2003
Homo sapiens
Fu, JF; Takeda, Y; Sendo, F; Araki, Y
[Different impacts of DMSO and RA on GPI-80 expression]
Shi Yan Sheng Wu Xue Bao
38
37-44
2005
Homo sapiens
Anzai-Takeda, Y; Takeda, Y; Sendo, F; Araki, Y
Inhibition of cell spreading in CHO cells transfected with cDNA of a glycosylphosphatidyl inositol-anchored protein, GPI-80.
Immunobiology
210
1-10
2005
Cricetulus griseus
Dammanahalli, KJ; Stevens, S; Terkeltaub, R
Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia.
PLoS One
7
e39106
2012
Mus musculus
Motomura, W; Yoshizaki, T; Takahashi, N; Kumei, S; Mizukami, Y; Jang, SJ; Kohgo, Y
Analysis of vanin-1 upregulation and lipid accumulation in hepatocytes in response to a high-fat diet and free fatty acids.
J Clin Biochem Nutr
51
163-9
2012
Mus sp.
Nitto, T; Onodera, K
The linkage between coenzyme a metabolism and inflammation: roles of pantetheinase.
J Pharmacol Sci
123
1-8
2013
Homo sapiens, Mammalia, Mus sp.
de Villiers, M; Macuamule, C; Spry, C; Hyun, YM; Strauss, E; Saliba, KJ
Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity.
ACS Med Chem Lett
4
784-9
2013
Plasmodium falciparum
Schalkwijk, J; Jansen, P
Chemical biology tools to study pantetheinases of the vanin family.
Biochem Soc Trans
42
1052-5
2014
Mus sp.
Naquet, P; Pitari, G; Dupr, S; Galland, F
Role of the Vnn1 pantetheinase in tissue tolerance to stress.
Biochem Soc Trans
42
1094-100
2014
Homo sapiens, Mus sp.
Takeda, Y; Kato, T; Ito, H; Kurota, Y; Yamagishi, A; Sakurai, T; Araki, A; Nara, H; Tsuchiya, N; Asao, H
The pattern of GPI-80 expression is a useful marker for unusual myeloid maturation in peripheral blood.
Clin Exp Immunol
2016
Homo sapiens
Hu, Y; Li, H; Shi, W; Ma, H
A Ratiometric Fluorescent Probe for Imaging of Pantetheinase in Living Cells.
Anal Chem
2017
Homo sapiens, Bos taurus
Kato, T; Takeda, Y; Ito, H; Kurota, Y; Yamagishi, A; Sakurai, T; Naito, S; Araki, A; Nara, H; Asao, H; Tsuchiya, N
GPI-80 as a Useful Index for Myeloid Cell Heterogeneity and a Potential Prognostic Biomarker for Metastatic Renal Cell Carcinoma.
Tohoku J Exp Med
249
203-212
2019
Homo sapiens
Chen, S; Zhang, W; Sun, C; Song, M; Liu, S; Xu, M; Zhang, X; Liu, L; Liu, C
Systemic Nanoparticle-Mediated Delivery of Pantetheinase Vanin-1 Regulates Lipolysis and Adiposity in Abdominal White Adipose Tissue.
Adv Sci (Weinh)
7
2000542
2020
Homo sapiens, Mus sp.
Qian, J; Zhang, L; Wang, J; Teng, Z; Cao, T; Zheng, L; Cao, Y; Qin, W; Liu, Y; Guo, H
Red emission ratio fluorescent probe for the activity of vanin-1 and imaging in vivo.
J Hazard Mater
401
123863
2021
Mus sp.
Unterschemmann, K; Ehrmann, A; Herzig, I; Andreevski, AL; Lustig, K; Schmeck, C; Eitner, F; Grundmann, M
Pharmacological inhibition of Vanin-1 is not protective in models of acute and chronic kidney disease.
Am J Physiol Renal Physiol
320
F61-F73
2021
Homo sapiens, Mus sp.
Lu, P; Zhang, C; Fu, L; Wei, Y; Huang, Y; Wang, X; Lv, C; Chen, L
Near-Infrared Fluorescent Probe for Imaging and Evaluating the Role of Vanin-1 in Chemotherapy.
Anal Chem
93
10378-10387
2021
Mus sp.
Pothuraju, R; Rachagani, S; Junker, WM; Chaudhary, S; Saraswathi, V; Kaur, S; Batra, SK
Pancreatic cancer associated with obesity and diabetes: an alternative approach for its targeting.
J Exp Clin Cancer Res
37
319
2018
Microbiota
Howieson, VM; Tran, E; Hoegl, A; Fam, HL; Fu, J; Sivonen, K; Li, XX; Auclair, K; Saliba, KJ
Triazole substitution of a labile amide bond stabilizes pantothenamides and improves their antiplasmodial potency.
Antimicrob Agents Chemother
2016
Homo sapiens
Barnard, L; Mostert, KJ; van Otterlo, WAL; Strauss, E
Developing Pantetheinase-Resistant Pantothenamide Antibacterials: Structural Modification Impacts on PanK Interaction and Mode of Action.
ACS Infect Dis
2018
Homo sapiens
Guan, J; Tjhin, ET; Howieson, VM; Kittikool, T; Spry, C; Saliba, KJ; Auclair, K
Structure-Activity Relationships of Antiplasmodial Pantothenamide Analogues Reveal a New Way by Which Triazoles Mimic Amide Bonds.
ChemMedChem
13
2677-2683
2018
Homo sapiens
O'Brian, CA; Chu, F
Post-translational disulfide modifications in cell signaling--role of inter-protein, intra-protein, S-glutathionyl, and S-cysteaminyl disulfide modifications in signal transmission.
Free Radic Res
39
471-80
2005
Mus sp.
Ling, L; Lu, HT; Wang, HF; Shen, MJ; Zhang, HB
MicroRNA-203 Acts as a Potent Suppressor in Septic Shock by Alleviating Lung Injury via Inhibition of VNN1.
Kidney Blood Press Res
44
565-582
2019
Mus musculus
Chen, HW; Chen, JJ; Yu, SL; Li, HN; Yang, PC; Su, CM; Au, HK; Chang, CW; Chien, LW; Chen, CS; Tzeng, CR
Transcriptome analysis in blastocyst hatching by cDNA microarray.
Hum Reprod
20
2492-501
2005
Saccharomyces cerevisiae
Murgola, EJ; Pagel, FT; Hijazi, KA
Codon context effects in missense suppression.
J Mol Biol
175
19-27
1984
Escherichia coli
Nakamura-Sato, Y; Sasaki, K; Watanabe, H; Araki, Y; Sendo, F
Clustering on the forward surfaces of migrating neutrophils of a novel GPI-anchored protein that may regulate neutrophil adherence and migration.
J Leukoc Biol
68
650-4
2000
Areas, Electron
Inoue, T; Kato, T; Hikichi, Y; Hashimoto, S; Hirase, T; Morooka, T; Imoto, Y; Takeda, Y; Sendo, F; Node, K
Stent-induced neutrophil activation is associated with an oxidative burst in the inflammatory process, leading to neointimal thickening.
Thromb Haemost
95
43-8
2006
Homo sapiens
Gensollen, T; Bourges, C; Rihet, P; Rostan, A; Millet, V; Noguchi, T; Bourdon, V; Sobol, H; Dubuquoy, L; Bertin, B; Fumery, M; Desreumaux, P; Colombel, JF; Hebuterne, X; Hofman, P; Naquet, P; Galland, F
Functional Polymorphisms in the Regulatory Regions of the VNN1 Gene Are Associated with Susceptibility to Inflammatory Bowel Diseases.
Inflamm Bowel Dis
19
2315-2325
2013
Mus musculus
Rommelaere, S; Millet, V; Vu Manh, TP; Gensollen, T; Andreoletti, P; Cherkaoui-Malki, M; Bourges, C; Escalire, B; Du, X; Xia, Y; Imbert, J; Beutler, B; Kanai, Y; Malissen, B; Malissen, M; Tailleux, A; Staels, B; Galland, F; Naquet, P
Sox17 regulates liver lipid metabolism and adaptation to fasting.
PLoS One
9
e104925
2014
Mus musculus, Mus sp.
Mariani, F; Roncucci, L
Role of the Vanins-Myeloperoxidase Axis in Colorectal Carcinogenesis.
Int J Mol Sci
18
2017
Homo sapiens
Hosohata, K
Biomarkers for Chronic Kidney Disease Associated with High Salt Intake.
Int J Mol Sci
18
2017
Rattus, animal
Wan, G; Ji, L; Xia, W; Cheng, L; Zhang, Y
Screening genes associated with elevated neutrophil?to?lymphocyte ratio in chronic heart failure.
Mol Med Rep
18
1415-1422
2018
Homo sapiens
Guan, J; Spry, C; Tjhin, ET; Yang, P; Kittikool, T; Howieson, VM; Ling, H; Starrs, L; Duncan, D; Burgio, G; Saliba, KJ; Auclair, K
Exploring Heteroaromatic Rings as a Replacement for the Labile Amide of Antiplasmodial Pantothenamides.
J Med Chem
64
4478-4497
2021
Plasmodium falciparum, Plasmodium knowlesi
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