Information on EC 3.5.1.8 - formylaspartate deformylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Pseudomonas sp.

EC NUMBER
COMMENTARY hide
3.5.1.8
-
RECOMMENDED NAME
GeneOntology No.
formylaspartate deformylase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N-formyl-L-aspartate + H2O = formate + L-aspartate
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of carboxylic acid amide
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Glyoxylate and dicarboxylate metabolism
-
-
Histidine metabolism
-
-
histidine metabolism
-
-
SYSTEMATIC NAME
IUBMB Comments
N-formyl-L-aspartate amidohydrolase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9025-09-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain ATCC 11299B, formylase I + II
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl-L-glutamic acid + H2O
acetate + L-glutamate
show the reaction diagram
-
only formylase II
-
?
chloroacetyl L-aspartic acid + H2O
chloroacetate + L-aspartate
show the reaction diagram
-
addition of Co2+ required
-
?
formylglutamic acid + H2O
formate + glutamate
show the reaction diagram
-
only formylase II
-
?
N-formyl-L-aspartate + H2O
formate + L-aspartate
show the reaction diagram
-
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mn2+
-
only formylase II
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.25 - 1.32
N-formyl-L-aspartate
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5940
-
formylase I
21000
-
formylase II
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7
-
formylase I
8
-
formylase II
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE