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Reference on EC 3.5.1.6 - beta-ureidopropionase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tamaki, N.; Mizutani, N.; Kikugawa, M.; Fujimoto, S.; Mizota, C.
Purification and properties of beta-ureidopropionase from the rat liver
Eur. J. Biochem.
169
21-26
1987
Rattus rattus
Manually annotated by BRENDA team
Matthews, M.M.; Traut, T.W.
Regulation of N-carbamoyl-beta-alanine amidohydrolase, the terminal enzyme in pyrimidine catabolism, by ligand-induced change in polymerization
J. Biol. Chem.
262
7232-7237
1987
Clostridium uracilicum, Euglena gracilis, Homo sapiens, Mus musculus, Rattus rattus, Clostridium uracilicum M5-2
Manually annotated by BRENDA team
Traut, T.W.; Loechel, S.
Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay
Biochemistry
23
2533-2539
1984
Escherichia coli, Euglena gracilis, Mus musculus, Rattus rattus
Manually annotated by BRENDA team
Hardiman, M.K.; Alfant, M.; Wakelin, V.P.; Tremblay, G.C.
Capacity of rat liver for pyrimidine synthesis and catabolism during fetal and neonatal development
Arch. Biochem. Biophys.
224
326-331
1983
Rattus rattus, Rattus rattus Cd
Manually annotated by BRENDA team
Kaspari, H.
Repression of beta-ureidopropionase by ammonia in Rhodopseudomonas capsulata
J. Gen. Microbiol.
122
95-100
1981
Clostridium uracilicum, Euglena gracilis, Rattus rattus, Rhodobacter capsulatus, Clostridium uracilicum M5-2
-
Manually annotated by BRENDA team
Wasternack, C.; Lippmann, G.; Reinbotte, H.
Pyrimidine-degrading enzymes purification and properties of beta-ureidopropionase of Euglena gracilis
Biochim. Biophys. Acta
570
341-351
1979
Clostridium uracilicum, Euglena gracilis, Mus musculus, Rattus rattus, Clostridium uracilicum M5-2
Manually annotated by BRENDA team
Campbell, L.L.
Reductive degradation of pyrimidines. V. Enzymatic conversion of N-carbamyl-beta-alanine to beta-alanine, carbon dioxide and ammonia
J. Biol. Chem.
235
2375-2379
1960
Canis lupus familiaris, Clostridium uracilicum, Oryctolagus cuniculus, Pigeon, Rattus rattus, Clostridium uracilicum M5-2
Manually annotated by BRENDA team
Caravaca, J.; Grisolia, S.
Enzymatic decarbamylation of carbamyl beta-alanine and carbamyl beta-aminoisobutyric acid
J. Biol. Chem.
231
357-365
1958
Canis lupus familiaris, Oryctolagus cuniculus, Pigeon, Rattus rattus
Manually annotated by BRENDA team
Waldmann, G.; Podschun, B.
Assay for beta-ureidopropionase by high-performance liquid chromatography
Anal. Biochem.
188
233-236
1990
Bos taurus, Clostridium uracilicum, Euglena gracilis, Mus musculus, Rattus rattus
Manually annotated by BRENDA team
Ogawa, J.; Shimizu, S.
beta-Ureidopropionase with N-carbamoyl-alpha-L-amino acid amidohydrolase activity from an aerobic bacterium, Pseudomonas putida IFO 12996
Eur. J. Biochem.
223
625-630
1994
Clostridium uracilicum, Comamonas sp., Euglena gracilis, Mus musculus, Pseudomonas putida, Rattus rattus
Manually annotated by BRENDA team
Ogawa, J.; Kaimura, T.; Yamada, H.; Shimizu, S.
Evaluation of pyrimidine- and hydantoin-degrading enzyme activities in aerobic bacteria
FEMS Microbiol. Lett.
122
55-60
1994
Agrobacterium sp., Arthrobacter sp., Bacillus sp. (in: Bacteria), Blastobacter sp., Comamonas sp., Pseudomonas putida, Comamonas sp. E222c
-
Manually annotated by BRENDA team
West, T.P.
Reductive catabolism of uracil and thymine by Burkholderia cepacia
Arch. Microbiol.
168
237-239
1997
Burkholderia cepacia
-
Manually annotated by BRENDA team
Van Kuilenburg, A.B.P.; Van Lenthe, H.; Van Gennip, A.H.
A radiochemical assay for beta-ureidopropionase using radiolabeled N-carbamyl-beta-alanine obtained via hydrolysis of [2-14C]5,6-dihydrouracil
Anal. Biochem.
272
250-253
1999
Homo sapiens, Rattus rattus
Manually annotated by BRENDA team
Vreken, P.; van Kuilenburg, A.B.P.; Hamajima, N.; Meinsma, R.; van Lenthe, H.; Goehlich-Ratmann, G.; Assmann, B.E.; Wevers, R.A.; van Gennip, A.H.
cDNA cloning, genomic structure and chromosomal localization of the human BUP-1 gene encoding beta-ureidopropionase
Biochim. Biophys. Acta
1447
251-257
1999
Rattus rattus, Homo sapiens (Q9UBR1), Homo sapiens
Manually annotated by BRENDA team
Dobritzsch, D.; Gojkovic, Z.; Andersen, B.; Piskur, J.
Crystallization and preliminary X-ray analysis of beta-alanine synthase from the yeast Saccharomyces kluyveri
Acta Crystallogr. Sect. D
59
1267-1269
2003
Lachancea kluyveri
Manually annotated by BRENDA team
Lundgren, S.; Gojkovic, Z.; Piskur, J.; Dobritzsch, D.
Yeast beta-alanine synthase shares a structural scaffold and origin with dizinc-dependent exopeptidases
J. Biol. Chem.
278
51851-51862
2003
Lachancea kluyveri (Q96W94), Lachancea kluyveri
Manually annotated by BRENDA team
Traut, T.W.
beta-Alanine synthase, an enzyme involved in catabolism of uracil and thymine
Methods Enzymol.
324
399-410
2000
Rattus norvegicus
Manually annotated by BRENDA team
Walsh, T.A.; Green, S.B.; Larrinua, I.M.; Schmitzer, P.R.
Characterization of plant beta-ureidopropionase and functional overexpression in Escherichia coli
Plant Physiol.
125
1001-1011
2001
Arabidopsis sp., Zea mays
Manually annotated by BRENDA team
Rawls, J.M.
Analysis of pyrimidine catabolism in Drosophila melanogaster using epistatic interactions with mutations of pyrimidine biosynthesis and beta-alanine metabolism
Genetics
172
1665-1674
2006
Drosophila melanogaster
Manually annotated by BRENDA team
West, T.P.
Pyrimidine base catabolism in Pseudomonas putida biotype B
Antonie van Leeuwenhoek
80
163-167
2001
Pseudomonas putida
Manually annotated by BRENDA team
Lundgren, S.; Andersen, B.; Piskur, J.; Dobritzsch, D.
Crystallization and preliminary X-ray data analysis of beta-alanine synthase from Drosophila melanogaster
Acta Crystallogr. Sect. F
63
874-877
2007
Drosophila melanogaster
Manually annotated by BRENDA team
Schnackerz, K.D.; Dobritzsch, D.
Amidohydrolases of the reductive pyrimidine catabolic pathway: Purification, characterization, structure, reaction mechanisms and enzyme deficiency
Biochim. Biophys. Acta
1784
431-444
2008
Arabidopsis thaliana, Bos taurus, Caenorhabditis elegans, Dictyostelium discoideum, Drosophila melanogaster, Euglena gracilis, Homo sapiens, Pseudomonas putida, Rattus norvegicus, Zea mays, Lachancea kluyveri
Manually annotated by BRENDA team
Lundgren, S.; Andersen, B.; Piskur, J.; Dobritzsch, D.
Crystal structures of yeast beta-alanine synthase complexes reveal the mode of substrate binding and large scale domain closure movements
J. Biol. Chem.
282
36037-36047
2007
Lachancea kluyveri (Q96W94), Lachancea kluyveri
Manually annotated by BRENDA team
Lundgren, S.; Lohkamp, B.; Andersen, B.; Piskur, J.; Dobritzsch, D.
The crystal structure of beta-alanine synthase from Drosophila melanogaster reveals a homooctameric helical turn-like assembly
J. Mol. Biol.
377
1544-1559
2008
Drosophila melanogaster
Manually annotated by BRENDA team
van Kuilenburg, A.B.; van Lenthe, H.; van Gennip, A.H.
Activity of pyrimidine degradation enzymes in normal tissues
Nucleosides Nucleotides Nucleic Acids
25
1211-1214
2006
Homo sapiens
Manually annotated by BRENDA team
Thomas, H.R.; Ezzeldin, H.H.; Guarcello, V.; Mattison, L.K.; Fridley, B.L.; Diasio, R.B.
Genetic regulation of beta-ureidopropionase and its possible implication in altered uracil catabolism
Pharmacogenet. Genomics
18
25-35
2008
Homo sapiens
Manually annotated by BRENDA team
Martinez-Gomez, A.I.; Martinez-Rodriguez, S.; Pozo-Dengra, J.; Tessaro, D.; Servi, S.; Clemente-Jimenez, J.M.; Rodriguez-Vico, F.; Las Heras-Vazquez, F.J.
Potential application of N-carbamoyl-beta-alanine amidohydrolase from Agrobacterium tumefaciens C58 for beta-amino acid production
Appl. Environ. Microbiol.
75
514-520
2009
Agrobacterium tumefaciens, Agrobacterium tumefaciens C58 / ATCC 33970
Manually annotated by BRENDA team
Zrenner, R.; Riegler, H.; Marquard, C.R.; Lange, P.R.; Geserick, C.; Bartosz, C.E.; Chen, C.T.; Slocum, R.D.
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis
New Phytol.
183
117-132
2009
Arabidopsis thaliana (Q8H183)
Manually annotated by BRENDA team
Kuhara, T.; Ohse, M.; Inoue, Y.; Shinka, T.
Five cases of beta-ureidopropionase deficiency detected by GC/MS analysis of urine metabolome
J. Mass Spectrom.
44
214-221
2009
Homo sapiens
Manually annotated by BRENDA team
Janowitz, T.; Ajonina, I.; Perbandt, M.; Woltersdorf, C.; Hertel, P.; Liebau, E.; Gigengack, U.
The 3-ureidopropionase of Caenorhabditis elegans, an enzyme involved in pyrimidine degradation
FEBS J.
277
4100-4109
2010
Caenorhabditis elegans (Q19437), Caenorhabditis elegans
Manually annotated by BRENDA team
Martinez-Gomez, A.I.; Andujar-Sanchez, M.; Clemente-Jimenez, J.M.; Neira, J.L.; Rodriguez-Vico, F.; Martinez-Rodriguez, S.; Las Heras-Vazquez, F.J.
N-Carbamoyl-beta-alanine amidohydrolase from Agrobacterium tumefaciens C58: a promiscuous enzyme for the production of amino acids
J. Chromatogr. B
879
3277-3282
2011
Agrobacterium tumefaciens, Agrobacterium tumefaciens C58 / ATCC 33970
Manually annotated by BRENDA team
Van Kuilenburg, A.; Dobritzsch, D.; Meijer, J.; Krumpel, M.; Selim, L.; Rashed, M.; Assmann, B.; Meinsma, R.; Lohkamp, B.; Ito, T.; Abeling, N.; Saito, K.; Eto, K.; Smitka, M.; Engvall, M.; Zhang, C.; Xu, W.; Zoetekouw, L.; Hennekam, R.
beta-Ureidopropionase deficiency: phenotype, genotype and protein structural consequences in 16 patients
Biochim. Biophys. Acta
1822
1096-1108
2012
Homo sapiens (Q9UBR1)
Manually annotated by BRENDA team
Lam, C.W.; Law, C.Y.; Leung, K.F.; Lai, C.K.; Pak-lam Chen, S.; Chan, B.; Chan, K.Y.; Yuen, Y.P.; Mak, C.M.; Yan-wo Chan, A.
NMR-based urinalysis for rapid diagnosis of beta-ureidopropionase deficiency in a patient with Dravet syndrome
Clin. Chim. Acta
440
201-204
2015
Homo sapiens (Q9UBR1), Homo sapiens
Manually annotated by BRENDA team
Meijer, J.; Nakajima, Y.; Zhang, C.; Meinsma, R.; Ito, T.; Van Kuilenburg, A.B.
Publishers note. Identification of a novel synonymous mutation in the human beta-ureidopropionase gene UPB1 affecting pre-mRNA splicing
Nucleosides Nucleotides Nucleic Acids
33
639-645
2014
Homo sapiens (Q9UBR1)
Manually annotated by BRENDA team
Fidlerova, J.; Kleiblova, P.; Kormunda, S.; Novotny, J.; Kleibl, Z.
Contribution of the beta-ureidopropionase (UPB1) gene alterations to the development of fluoropyrimidine-related toxicity
Pharmacol. Rep.
64
1234-1242
2012
Homo sapiens (Q9UBR1)
Manually annotated by BRENDA team
Shen, Y.; Chen, Y.; Liu, H.; Chiang, F.; Wang, Y.; Hou, L.; Lin, J.; Lin, C.; Lin, H.; Lai, H.; Jeng, S.
Expression of a gene encoding beta-ureidopropionase is critical for pollen germination in tomatoes
Physiol. Plant.
150
425-435
2014
Solanum lycopersicum, Solanum lycopersicum CL5915, Solanum lycopersicum L4783
Manually annotated by BRENDA team
Maurer, D.; Lohkamp, B.; Krumpel, M.; Widersten, M.; Dobritzsch, D.
Crystal structure and pH-dependent allosteric regulation of human beta-ureidopropionase, an enzyme involved in anticancer drug metabolism
Biochem. J.
475
2395-2416
2018
Homo sapiens (Q9UBR1)
Manually annotated by BRENDA team
Kummer, D.; Froehlich, T.K.; Joerger, M.; Aebi, S.; Sistonen, J.; Amstutz, U.; Largiader, C.R.
Dihydropyrimidinase and beta-ureidopropionase gene variation and severe fluoropyrimidine-related toxicity
Pharmacogenomics
16
1367-1377
2015
Homo sapiens (Q9UBR1)
Manually annotated by BRENDA team