Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 3.5.1.41 - chitin deacetylase and Organism(s) Schizosaccharomyces pombe and UniProt Accession O13842

for references in articles please use BRENDA:EC3.5.1.41
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.41 chitin deacetylase
IUBMB Comments
Hydrolyses the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Schizosaccharomyces pombe
UNIPROT: O13842
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Schizosaccharomyces pombe
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
chitin deacetylase, lmcda2, lmcda1, bmcda7, cdayj, bmcda8, chitin deacetylase 1, fv-pda, ancda, clcda, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
chitin amidohydrolase
Hydrolyses the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin.
CAS REGISTRY NUMBER
COMMENTARY hide
56379-60-3
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
chitin + H2O
chitosan + acetate
show the reaction diagram
-
plain chitin is a poor substrate, but glycolated, reprecipitated or depolymerized chitins are good ones
-
-
?
chitin oligomer + H2O
?
show the reaction diagram
-
-
-
-
?
chitin-50 + H2O
?
show the reaction diagram
-
-
-
-
?
GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc + H2O
GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN + 3 acetate
show the reaction diagram
-
-
-
-
?
GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc + H2O
GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN + 4 acetate
show the reaction diagram
-
-
-
-
?
GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc + H2O
GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN + 5 acetate
show the reaction diagram
-
-
-
-
?
GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc + H2O
GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN + 6 acetate
show the reaction diagram
-
-
-
-
?
GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc + H2O
GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN-beta-(1-4)-GlcN + 7 acetate
show the reaction diagram
-
-
-
-
?
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
chitin + H2O
chitosan + acetate
show the reaction diagram
-
plain chitin is a poor substrate, but glycolated, reprecipitated or depolymerized chitins are good ones
-
-
?
additional information
?
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
-
the enzyme activity of chitin deacetylase can be enhanced in the presence of Ca2+ (1 mM)
Co2+
-
the enzyme activity of chitin deacetylase can be enhanced in the presence of Co2+ (1 mM)
Zn2+
-
the enzyme activity of chitin deacetylase can be enhanced in the presence of Zn2+ (1 mM)
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
EDTA
-
addition of EDTA eliminates total chitin deacetylase activity
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene cda1+, several strains, overview
Uniprot
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
-
chitin deacetylase is required for proper spore formation
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene cda1+ or SPAC19G12.03, interaction analysis using the two-hybrid system in Saccharomyces cerevisiae strain L40
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Matsuo, Y.; Tanaka, K.; Matsuda, H.; Kawamukai, M.
cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe
FEBS Lett.
579
2737-2743
2005
Schizosaccharomyces pombe (O13842), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Zhao, Y.; Park, R.D.; Muzzarelli, R.A.
Chitin deacetylases: properties and applications
Mar. Drugs
8
24-46
2010
Absidia caerulea, Amylomyces rouxii, Anopheles gambiae, Apis mellifera, Aspergillus nidulans, Colletotrichum lindemuthianum, Cryptococcus neoformans, Drosophila melanogaster, Flammulina velutipes, Helicoverpa armigera, Mamestra configurata, Metarhizium anisopliae, Mortierella sp., Rhizopus circinans, Rhizopus stolonifer, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Scopulariopsis brevicaulis, Tribolium castaneum, Trichoplusia ni, Vibrio cholerae serotype O1
Manually annotated by BRENDA team