Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 3.5.1.2 - glutaminase

for references in articles please use BRENDA:EC3.5.1.2
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.2 glutaminase
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
UNIPROT: O14907 not found.
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
glutaminase, l-glutaminase, phosphate-activated glutaminase, mitochondrial glutaminase, glutaminase 1, kidney-type glutaminase, phosphate activated glutaminase, glutaminase a, glnase, glutaminase c, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glutaminase L
-
phosphate-activated glutaminase
-
GLS
-
-
-
-
glutaminase I
-
-
-
-
glutamine aminohydrolase
-
-
-
-
K-glutaminase
-
-
-
-
L-glutaminase
-
-
-
-
L-glutamine amidohydrolase
-
-
-
-
PAG
-
-
-
-
phosphate activated glutaminase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
carboxylic acid amide hydrolysis
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
L-glutamine amidohydrolase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9001-47-2
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-glutamine + H2O
L-glutamate + NH3
show the reaction diagram
synthesis of neurotransmitter glutamate and regulates the concentrations of glutamine and glutamate, ammonia detoxification
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-glutamine + H2O
L-glutamate + NH3
show the reaction diagram
synthesis of neurotransmitter glutamate and regulates the concentrations of glutamine and glutamate, ammonia detoxification
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
TX1B3_HUMAN
124
0
13735
Swiss-Prot
-
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
13740
calculation from sequence of cDNA
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
no modification
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in yeast strain EGY48
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Olalla, L.; Aledo, J.C.; Bannenberg, G.; Marquez, J.
The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins
FEBS Lett.
488
116-122
2001
Homo sapiens (O14907), Homo sapiens
Manually annotated by BRENDA team