Information on EC 3.5.1.127 - jasmonoyl-L-amino acid hydrolase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.5.1.127
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RECOMMENDED NAME
GeneOntology No.
jasmonoyl-L-amino acid hydrolase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a jasmonoyl-L-amino acid + H2O = jasmonate + an L-amino acid
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
jasmonoyl-L-isoleucine inactivation
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SYSTEMATIC NAME
IUBMB Comments
jasmonoyl-L amino acid amidohydrolase
This entry includes a family of enzymes that recyle jasmonoyl-amino acid conjugates back to jasmonates. The enzymes from Arabidopsis thaliana have been shown to also act on 12-hydroxyjasmonoyl-L-isoleucine, generating tuberonic acid.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
12-hydroxyjasmonoyl-L-isoleucine + H2O
12-hydroxyjasmonic acid + L-isoleucine
show the reaction diagram
indole acetic acid-L-alanine + H2O
indole acetic acid + L-alanine
show the reaction diagram
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?
indole-3-acetic-acid-L-alanine + H2O
indole-3-acetic acid + L-alanine
show the reaction diagram
jasmonoyl-L-glutamine + H2O
jasmonic acid + L-glutamine
show the reaction diagram
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?
jasmonoyl-L-isoleucine + H2O
jasmonic acid + L-isoleucine
show the reaction diagram
jasmonoyl-L-leucine + H2O
jasmonic acid + L-leucine
show the reaction diagram
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?
jasmonoyl-L-phenylalanine + H2O
jasmonic acid + L-phenylalanine
show the reaction diagram
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?
jasmonoyl-L-threonine + H2O
jasmonic acid + L-threonine
show the reaction diagram
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?
jasmonoyl-L-valine + H2O
jasmonic acid + L-valine
show the reaction diagram
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?
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
indole acetic acid-L-alanine + H2O
indole acetic acid + L-alanine
show the reaction diagram
Q8VYX0
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?
jasmonoyl-L-isoleucine + H2O
jasmonic acid + L-isoleucine
show the reaction diagram
Q8VYX0
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?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mn2+
optimal divalent cation
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0000014
jasmonoyl-L-glutamine, pH 8.0, 28°C
0.0000015
jasmonoyl-L-valine, pH 8.0, 28°C
0.0000021
12hydroxyjasmonoyl-L-isoleucine, pH 8.0, 28°C
0.0000022
jasmonoyl-L-threonine, pH 8.0, 28°C
0.0000039
jasmonoyl-L-leucine, pH 8.0, 28°C
0.0000085
jasmonoyl-L-isoleucine, pH 8.0, 28°C
0.000045
12hydroxyjasmonoyl-L-isoleucine, pH 8.0, 28°C; jasmonoyl-L-glutamine, pH 8.0, 28°C
0.000052
jasmonoyl-L-valine, pH 8.0, 28°C
0.000059
jasmonoyl-L-isoleucine, pH 8.0, 28°C
0.000064
jasmonoyl-L-phenylalanine, pH 8.0, 28°C
0.000067
jasmonoyl-L-threonine, pH 8.0, 28°C
0.000084
jasmonoyl-L-leucine, pH 8.0, 28°C
0.000456
indole-3-acetic-acid-L-alanine, pH 8.0, 28°C
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Ill6 colocalizes with the endoplasmic reticulum-localized jasmonoyl-isoleucine 12-hydroxylase, CYP94B3; Ill6 colocalizes with the endoplasmic reticulum-localized jasmonoyl-isoleucine 12-hydroxylase, CYP94B3
Manually annotated by BRENDA team
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli; expression in Escherichia coli
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression of aminohydrolases Ilr1, Ill6 and Iar3 in leaves is up-regulated by wounding or jasmonic acid, but not by indole-3-acetic acid; expression of aminohydrolases Ilr1, Ill6 and Iar3 in leaves is up-regulated by wounding or jasmonic acid, but not by indole-3-acetic acid
gene expression is strongly upregulated by herbivory
rapid and transient induction upon wounding; rapid and transient induction upon wounding