Information on EC 3.5.1.118 - gamma-glutamyl hercynylcysteine S-oxide hydrolase

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The expected taxonomic range for this enzyme is: Mycobacterium smegmatis

EC NUMBER
COMMENTARY hide
3.5.1.118
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RECOMMENDED NAME
GeneOntology No.
gamma-glutamyl hercynylcysteine S-oxide hydrolase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O = S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
ergothioneine biosynthesis I (bacteria)
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Histidine metabolism
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SYSTEMATIC NAME
IUBMB Comments
S-gamma-glutamyl hercynylcysteine S-oxide amidohydrolase
The enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O
S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O
S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
show the reaction diagram
PDB
SCOP
CATH
ORGANISM
UNIPROT
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
24139
x * 24139, calculated from sequence
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Show AA Sequence (721 entries)
Please use the Sequence Search for a specific query.