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2'-N-acetylparomamine hydrolase (acetate-forming)
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. The enzyme from the bacterium Streptomyces fradiae can also accept 2'''-acetyl-6'''-hydroxyneomycin C as substrate, cf. EC 18.104.22.168, 2'''-acetyl-6'''-hydroxyneomycin C deacetylase .